Stigmasterol Exerts Neuro-Protective Effect Against Ischemic/Reperfusion Injury Through Reduction Of Oxidative Stress And Inactivation Of Autophagy.

abstract：:With respect to the high burden of ischemic stroke and the absence of pharmacological treatment for promoting rehabilitation, promising candidates with specific effects on long-term functional recovery are highly desired. Candidates need reasonable experimental paradigms to evaluate the long-term functional outcome fo...

journal_title：Neuropsychiatric disease and treatment

authors： Jiao CX,Zhou H,Yang CX,Ma C,Yang YX,Mao RR,Xu L,Zhou QX

更新日期：2017-04-26 00:00:00

abstract：Background:Evidence has shown that microRNAs (miRNAs) are implicated in ischemic diseases. Therefore, the aim of the present study was to identify the functions of astrocyte (ATC)-derived exosomal miR-361 on cerebral ischemic-reperfusion (I/R) injury. Methods:A rat model of cerebral I/R injury was initially establishe...

journal_title：Neuropsychiatric disease and treatment

authors： Bu X,Li D,Wang F,Sun Q,Zhang Z

更新日期：2020-07-31 00:00:00

abstract：:Family history, which includes both common environmental and genetic effects, is associated with an increased risk for many neuropsychiatric diseases. Investigators have identified several disease-causing mutations for specific neuropsychiatric disorders that display Mendelian segregation. Such discoveries can lead to...

journal_title：Neuropsychiatric disease and treatment

authors： Keller MA,Gwinn K,Nash J,Horsford J,Zhang R,Rich SS,Corriveau RA

更新日期：2007-01-01 00:00:00

abstract：:Obsessive compulsive and impulsive symptoms are prevalent in patients with Tourette's Syndrome (TS) and well recognized as part of the TS spectrum. However, some complex obsessive compulsive and impulsive behaviors may be mistaken for other symptoms, such as complex tics or psychotic behavior. In addition, the overlap...

journal_title：Neuropsychiatric disease and treatment

authors： Palumbo D,Kurlan R

更新日期：2007-01-01 00:00:00

abstract：Background:Impulsivity is one of the principal symptoms of bipolar and related disorders (BD). Unsafe sex and unplanned pregnancies are serious problems in clinical practice. The aim of this study was to investigate impulsivity levels, contraception methods, and levels of planned pregnancies among women with bipolar an...

journal_title：Neuropsychiatric disease and treatment

authors： Zengin Eroglu M,Lus MG

更新日期：2020-02-07 00:00:00

abstract：:We report a case in which selegiline, an irreversible monoamine oxidase B (MAO-B) inhibitor, greatly improved depressive symptoms in an adult with stage 5 treatment-resistant major depressive disorder. Four antidepressants and four augmentation therapies had previously been ineffective or intolerable, and electroconvu...

journal_title：Neuropsychiatric disease and treatment

authors： Kitaichi Y,Inoue T,Mitsui N,Nakagawa S,Kameyama R,Hayashishita Y,Shiga T,Kusumi I,Koyama T

更新日期：2013-01-01 00:00:00

abstract：:Whipple disease (WD) is a rare systemic disorder caused by the bacteria Tropheryma whipplei. In its classic form, it manifests with gastrointestinal problems including diarrhea, abdominal pain, and weight loss. However, various other systems can be affected, including the central nervous system (CNS). Even more rarely...

journal_title：Neuropsychiatric disease and treatment

authors： Peregrin J,Malikova H

更新日期：2015-09-25 00:00:00

abstract：AIMS:This study aimed to analyze the scientific literature about social networks and social support in eating disorders (ED). METHODS:By combining keywords, an integrative review was performed. It included publications from 2006-2013, retrieved from the MEDLINE, LILACS, PsycINFO, and CINAHL databases. The selection of...

journal_title：Neuropsychiatric disease and treatment

authors： Leonidas C,Dos Santos MA

更新日期：2014-05-21 00:00:00

abstract：:Stem cells are self-renewing undifferentiated cells that give rise to multiple types of specialized cells of the body. In the adult, stem cells are multipotents and contribute to homeostasis of the tissues and regeneration after injury. Until recently, it was believed that the adult brain was devoid of stem cells, hen...

journal_title：Neuropsychiatric disease and treatment

authors： Taupin P

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:The primary objective of this prospective observational study was to evaluate changes in self-reported disability in patients with anxiety or mood disorders 3 months after initiating antidepressant treatment. METHODS:This study included 8396 patients consulting 2433 general practitioners in France for a maj...

journal_title：Neuropsychiatric disease and treatment

authors： Gérard A,Liard F,Crochard A,Goni S,Millet B

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To constitute the third revision of the guidelines for the treatment of bipolar disorder issued by the Korean Medication Algorithm Project for Bipolar Disorder (KMAP-BP 2014). METHODS:A 56-item questionnaire was used to obtain the consensus of experts regarding pharmacological treatment strategies for the va...

journal_title：Neuropsychiatric disease and treatment

authors： Woo YS,Lee JG,Jeong JH,Kim MD,Sohn I,Shim SH,Jon DI,Seo JS,Shin YC,Min KJ,Yoon BH,Bahk WM

更新日期：2015-02-26 00:00:00

abstract：Purpose:This study examined the links between 24-hour activity patterns (specifically, amplitude and timing of wrist activity) and the persisting qualities of clinical antidepressant response to the glutamatergic modulator ketamine. Methods:Twenty-four-hour activity patterns were compared across 5 days of 24-hour acti...

journal_title：Neuropsychiatric disease and treatment

authors： Duncan WC Jr,Slonena EE,Hejazi NS,Brutsche N,Park LT,Henter ID,Ballard ED,Zarate CA Jr

更新日期：2018-10-16 00:00:00

abstract：BACKGROUND:Migraine without aura (MoA) is a painful syndrome, particularly in childhood; it is often accompanied by severe impairments, including emotional dysfunction, absenteeism from school, and poor academic performance, as well as issues relating to poor cognitive function, sleep habits, and motor coordination. M...

journal_title：Neuropsychiatric disease and treatment

authors： Esposito M,Ruberto M,Gimigliano F,Marotta R,Gallai B,Parisi L,Lavano SM,Roccella M,Carotenuto M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Concurrent personality disorder (PD) and substance use disorder (SUD) are common in clinical practice. However, SUD is the main criterion for study exclusion in most psychotherapeutic studies of PD. As a result, data on treatment outcomes in patients with concurrent PD/SUD are scarce. METHODS:The study samp...

journal_title：Neuropsychiatric disease and treatment

authors： Lana F,Sánchez-Gil C,Adroher ND,Pérez V,Feixas G,Martí-Bonany J,Torrens M

更新日期：2016-06-21 00:00:00

abstract：OBJECTIVE OF THE STUDY:To evaluate the value of serum creatine phosphokinase-brain specific (CK-BB) and urinary lactate/creatinine (L/C) ratio as early indicators of brain damage in full-term newborns with hypoxic ischemic encephalopathy (HIE). PATIENTS AND METHODS:A case-control study including 25 full-term new-born ...

journal_title：Neuropsychiatric disease and treatment

authors： Alkholy UM,Abdalmonem N,Zaki A,Ali YF,Mohamed SA,Abdelsalam NI,Hashim MIA,Sekkien MA,Elsherbiny YM

更新日期：2017-08-08 00:00:00

abstract：INTRODUCTION:Antipsychotics are recommended as first-line therapy for acute mania and maintenance treatment of bipolar disorder; however, published literature suggests their real-world use remains limited. Understanding attitudes toward these medications may help identify barriers and inform personalized therapy. This ...

journal_title：Neuropsychiatric disease and treatment

authors： Sajatovic M,DiBiasi F,Legacy SN

更新日期：2017-08-30 00:00:00

abstract：PURPOSE:The aim of the study reported here was to examine the safety and effectiveness of high-frequency repetitive transcranial magnetic stimulation (rTMS) in elderly patients with depression. PATIENTS AND METHODS:Sixty-five depressed elderly patients received rTMS over their left prefrontal cortex for 6 days per wee...

journal_title：Neuropsychiatric disease and treatment

authors： Hizli Sayar G,Ozten E,Tan O,Tarhan N

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Bipolar disorder (BD) is a chronic, relapsing, episodic mental illness associated with other psychiatric comorbidities. There is a substantial economic burden with BD, which makes it challenging to treat. The aim of this review is to evaluate the pharmacology, clinical efficacy, and safety data related to pa...

journal_title：Neuropsychiatric disease and treatment

authors： Marino J,English C,Caballero J,Harrington C

更新日期：2012-01-01 00:00:00

abstract：:Dopaminergic agents, anticonvulsants, benzodiazepines, opiates, and iron supplementation comprise the classes of medications commonly used to treat restless legs syndrome (RLS), which is a disorder that is estimated to affect about 1 in 10 individuals worldwide and impacts an affected patient's sleep, mood, daytime fu...

journal_title：Neuropsychiatric disease and treatment

authors： Kushida CA

更新日期：2006-12-01 00:00:00

abstract：:Cognitive impairment is closely related to real-life functioning in patients with schizophrenia. The aim of the present study was to evaluate the effects of adjunctive treatment with donepezil on cognition in patients with chronic schizophrenia. This was a 12-week, double-blind, randomized, placebo-controlled study of...

journal_title：Neuropsychiatric disease and treatment

authors： Zhu W,Zhang Z,Qi J,Liu F,Chen J,Zhao J,Guo X

更新日期：2014-07-14 00:00:00

abstract：BACKGROUND:Mirtazapine, which is classified as a noradrenergic and specific serotonergic antidepressant, is widely prescribed for the treatment of major depressive disorder. The potential predictive factors of the efficacy of mirtazapine and the tolerability based on the incidence of oversedation and jitteriness/anxiet...

journal_title：Neuropsychiatric disease and treatment

authors： Tsutsumi T,Sugawara H,Ito R,Asano M,Shimizu S,Ishigooka J,Nishimura K

更新日期：2016-10-05 00:00:00

abstract：:Traumatic brain injury (TBI) is a well recognized public health problem worldwide. TBI has previously been considered as a rare cause of hypopituitarism, but an increased prevalence of neuroendocrine dysfunction in patients with TBI has been reported during the last 15 years in most of the retrospective and prospectiv...

journal_title：Neuropsychiatric disease and treatment

authors： Tanriverdi F,Kelestimur F

更新日期：2015-07-27 00:00:00

abstract：BACKGROUND:We aimed to investigate the current prevalence of sexual dysfunction (SD), mood, anxiety, and personality disorders in female patients with fibromyalgia (FM). METHODS:This case-control study involved 96 patients with FM and 94 healthy women. The SD diagnosis was based on a psychiatric interview in accordanc...

journal_title：Neuropsychiatric disease and treatment

authors： Kayhan F,Küçük A,Satan Y,İlgün E,Arslan Ş,İlik F

更新日期：2016-02-16 00:00:00

abstract：PURPOSE:Infant resting-state networks do not exhibit the same connectivity patterns as those of young children and adults. Current theories of brain development emphasize developmental progression in regional and network specialization. We compared infant and adult functional connectivity, predicting that infants would...

journal_title：Neuropsychiatric disease and treatment

authors： Wylie KP,Rojas DC,Ross RG,Hunter SK,Maharajh K,Cornier MA,Tregellas JR

更新日期：2014-07-21 00:00:00

abstract：BACKGROUND:Relapse is common in schizophrenia, and seriously impacts patients' quality of life and social functioning. Many factors have been identified that may potentially increase the risk of relapse. This study was designed to investigate the relapse rate in the year following hospital discharge among Chinese patie...

journal_title：Neuropsychiatric disease and treatment

authors： Xiao J,Mi W,Li L,Shi Y,Zhang H

更新日期：2015-05-08 00:00:00

abstract：:A plethora of research has implicated hundreds of putative biomarkers for depression, but has not yet fully elucidated their roles in depressive illness or established what is abnormal in which patients and how biologic information can be used to enhance diagnosis, treatment and prognosis. This lack of progress is par...

journal_title：Neuropsychiatric disease and treatment

authors： Strawbridge R,Young AH,Cleare AJ

更新日期：2017-05-10 00:00:00

abstract：:Parkinson's disease (PD) is one of the most frequent neurological diseases. Despite the modern imaging and nuclear techniques which help to diagnose it in a very early stage and lead to a better discrimination of similar diseases, PD has remained a clinical diagnosis. The increasing number of available treatment optio...

journal_title：Neuropsychiatric disease and treatment

authors： Pedrosa DJ,Timmermann L

更新日期：2013-01-01 00:00:00

abstract：:The purpose of this pilot study was to assess the efficacy of a new social cognition (SC) remediation intervention, the Social Cognition Individualized Activities Lab (SoCIAL), for subjects with schizophrenia. The training includes a module for emotion recognition and one for theory of mind. A comparison with a valida...

journal_title：Neuropsychiatric disease and treatment

authors： Palumbo D,Mucci A,Piegari G,D'Alise V,Mazza A,Galderisi S

更新日期：2017-07-20 00:00:00

abstract：BACKGROUND:The size and increasing burden of disease due to mental disorders in Europe poses substantial challenges to its population and to the health policy of the European Union. This warrants a specific research agenda concerning clinical mental health research as one of the cornerstones of sustainable mental healt...

journal_title：Neuropsychiatric disease and treatment

authors： van der Feltz-Cornelis CM,van Os J,Knappe S,Schumann G,Vieta E,Wittchen HU,Lewis SW,Elfeddali I,Wahlbeck K,Linszen D,Obradors-Tarragó C,Haro JM

更新日期：2014-06-27 00:00:00

abstract：BACKGROUND:Decreased relapse rate and slower disease progression have been reported with long-term use of immunomodulatory treatments (IMTs, interferon beta or glatiramer acetate) in relapsing-remitting multiple sclerosis. There are, however, patients who do not respond to such treatments, and they can be potential can...

journal_title：Neuropsychiatric disease and treatment

authors： Mezei Z,Bereczki D,Racz L,Csiba L,Csepany T

更新日期：2012-01-01 00:00:00