Protective Role of Astrocyte-Derived Exosomal microRNA-361 in Cerebral Ischemic-Reperfusion Injury by Regulating the AMPK/mTOR Signaling Pathway and Targeting CTSB.

abstract：:We report a case in which selegiline, an irreversible monoamine oxidase B (MAO-B) inhibitor, greatly improved depressive symptoms in an adult with stage 5 treatment-resistant major depressive disorder. Four antidepressants and four augmentation therapies had previously been ineffective or intolerable, and electroconvu...

journal_title：Neuropsychiatric disease and treatment

authors： Kitaichi Y,Inoue T,Mitsui N,Nakagawa S,Kameyama R,Hayashishita Y,Shiga T,Kusumi I,Koyama T

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:Many previous reports have demonstrated significant neural anatomy changes in the brain of high myopic (HM) patients, whereas the spontaneous brain activity changes in the HM patients at rest are not well studied. Our objective was to use amplitude of low-frequency fluctuation (ALFF) method to investigate the...

journal_title：Neuropsychiatric disease and treatment

authors： Huang X,Zhou FQ,Hu YX,Xu XX,Zhou X,Zhong YL,Wang J,Wu XR

更新日期：2016-11-14 00:00:00

abstract：BACKGROUND:The majority of previous neuroimaging studies have demonstrated both structural and functional abnormalities in obstructive sleep apnea (OSA). However, few studies have focused on the regional intensity of spontaneous fluctuations during the resting state and the relationship between the abnormal properties ...

journal_title：Neuropsychiatric disease and treatment

authors： Li HJ,Dai XJ,Gong HH,Nie X,Zhang W,Peng DC

更新日期：2015-01-23 00:00:00

abstract：BACKGROUND:Patients with schizophrenia show disturbances in both visual perception and social cognition. Perception of biological motion (BM) is a higher-level visual process, and is known to be associated with social cognition. BM induces activation in the "social brain network", including the superior temporal sulcus...

journal_title：Neuropsychiatric disease and treatment

authors： Hashimoto N,Toyomaki A,Hirai M,Miyamoto T,Narita H,Okubo R,Kusumi I

更新日期：2014-11-17 00:00:00

abstract：:Epilepsy is a common pediatric neurologic disorder that is difficult to manage in a substantial portion of children. Levetiracetam (LEV) is a novel antiepileptic drug (AED) that has recently been approved as add-on treatment for various seizure types in epilepsy populations that include children: for refractory partia...

journal_title：Neuropsychiatric disease and treatment

authors： Wheless JW

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Following the approval of lisdexamfetamine dimesylate (LDX) in several European countries for the treatment of attention-deficit/hyperactivity disorder (ADHD) in children and adolescents with an inadequate response to methylphenidate (MPH) treatment, the aim of the present analysis was to establish the respo...

journal_title：Neuropsychiatric disease and treatment

authors： Coghill DR,Banaschewski T,Lecendreux M,Soutullo C,Zuddas A,Adeyi B,Sorooshian S

更新日期：2014-10-29 00:00:00

abstract：BACKGROUND AND PURPOSE:Little is known about the functional and structural connectivity (FC and SC) of the hippocampus and amygdala, which are two important structures involved in cognitive processes, or their involvement in relapsing-remitting multiple sclerosis (RRMS). In this study, we aimed to examine the connectiv...

journal_title：Neuropsychiatric disease and treatment

authors： Zhou F,Zhuang Y,Wang L,Zhang Y,Wu L,Zeng X,Gong H

更新日期：2015-07-17 00:00:00

abstract：AIM:The relationship between psychological stress and platelet activation has been widely studied. It is well known that platelets may reflect certain biochemical changes that occur in the brain when different mental conditions occur. Platelet 5-hydroxytryptamine (5-HT) is also extensively studied in psychiatry. The me...

journal_title：Neuropsychiatric disease and treatment

authors： Göğçegöz Gül I,Eryılmaz G,Ozten E,Hızlı Sayar G

更新日期：2014-09-04 00:00:00

abstract：BACKGROUND:The size and increasing burden of disease due to mental disorders in Europe poses substantial challenges to its population and to the health policy of the European Union. This warrants a specific research agenda concerning clinical mental health research as one of the cornerstones of sustainable mental healt...

journal_title：Neuropsychiatric disease and treatment

authors： van der Feltz-Cornelis CM,van Os J,Knappe S,Schumann G,Vieta E,Wittchen HU,Lewis SW,Elfeddali I,Wahlbeck K,Linszen D,Obradors-Tarragó C,Haro JM

更新日期：2014-06-27 00:00:00

abstract：Purpose:Entropy analysis of resting-state functional magnetic resonance imaging (R-fMRI) has recently been adopted to characterize brain temporal dynamics in some neuropsychological or psychiatric diseases. Thalamus-related dysfunction might be a potential trait marker of major depressive disorder (MDD), but the abnorm...

journal_title：Neuropsychiatric disease and treatment

authors： Xue SW,Wang D,Tan Z,Wang Y,Lian Z,Sun Y,Hu X,Wang X,Zhou X

更新日期：2019-09-11 00:00:00

abstract：BACKGROUND:Oral cholinesterase inhibitors at doses efficacious for the treatment of Alzheimer's disease (AD) are often prematurely discontinued due to gastrointestinal side effects. In controlled clinical trials, transdermal rivastigmine demonstrated less such effects at similar efficacy. The current study aimed to ver...

journal_title：Neuropsychiatric disease and treatment

authors： Seibert J,Tracik F,Articus K,Spittler S

更新日期：2012-01-01 00:00:00

abstract：:Traumatic brain injury (TBI) remains the main cause of disability and a major public health problem worldwide. This review focuses on the neurophysiology of TBI, and the rationale and current state of evidence of clinical application of brain stimulation to promote TBI recovery, particularly on consciousness, cognitiv...

journal_title：Neuropsychiatric disease and treatment

authors： Li S,Zaninotto AL,Neville IS,Paiva WS,Nunn D,Fregni F

更新日期：2015-06-30 00:00:00

abstract：OBJECTIVE:The study aimed at exploring bereavement and complicated grief (CG) symptoms among subjects without a history of coronary heart disease (CHD) at the time of a first acute coronary syndrome (ACS) and to evaluate the relationship of CG symptoms and ACS. METHOD:Overall, 149 subjects with ACS (namely, acute myoc...

journal_title：Neuropsychiatric disease and treatment

authors： Pini S,Gesi C,Abelli M,Cardini A,Lari L,Felice F,Di Stefano R,Mazzotta G,Bovenzi F,Bertoli D,Borelli L,Michi P,Oligeri C,Balbarini A,Manicavasagar V

更新日期：2015-10-07 00:00:00

abstract：PURPOSE:The aim of the study reported here was to examine the safety and effectiveness of high-frequency repetitive transcranial magnetic stimulation (rTMS) in elderly patients with depression. PATIENTS AND METHODS:Sixty-five depressed elderly patients received rTMS over their left prefrontal cortex for 6 days per wee...

journal_title：Neuropsychiatric disease and treatment

authors： Hizli Sayar G,Ozten E,Tan O,Tarhan N

更新日期：2013-01-01 00:00:00

abstract：:Neuropsychiatric symptoms are common in older adults with dementia and can be associated with a rapid decline in cognitive and functional status. This article reviews the current literature supporting the use of atypical antipsychotic medications in this population. Among the currently available atypical antipsychotic...

journal_title：Neuropsychiatric disease and treatment

authors： Lee PE,Gill SS,Rochon P

更新日期：2006-12-01 00:00:00

abstract：:An 87-year-old woman had both Lewy body dementia and normal pressure hydrocephalus simultaneously. One should not automatically exclude the possibility of normal pressure hydrocephalus simply because another neurodegenerative disorder is present, especially if the second disorder masks typical symptoms of normal press...

journal_title：Neuropsychiatric disease and treatment

authors： Alisky J

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Metabolic syndrome (MetS) is one of the primary reasons for increased mortality in patients with schizophrenia. The mechanisms involved in its pathogenesis are not well understood. OBJECTIVE:To estimate the prevalence of MetS in adult outpatients with schizophrenia according to the presence or absence of ne...

journal_title：Neuropsychiatric disease and treatment

authors： Sicras-Mainar A,Maurino J,Ruiz-Beato E,Navarro-Artieda R

更新日期：2014-12-30 00:00:00

abstract：Purpose:This study examined the links between 24-hour activity patterns (specifically, amplitude and timing of wrist activity) and the persisting qualities of clinical antidepressant response to the glutamatergic modulator ketamine. Methods:Twenty-four-hour activity patterns were compared across 5 days of 24-hour acti...

journal_title：Neuropsychiatric disease and treatment

authors： Duncan WC Jr,Slonena EE,Hejazi NS,Brutsche N,Park LT,Henter ID,Ballard ED,Zarate CA Jr

更新日期：2018-10-16 00:00:00

abstract：PURPOSE:To investigate the perception of dignity among patients hospitalized in a psychiatric setting using the Patient Dignity Inventory (PDI), which had been first validated in oncologic field among terminally ill patients. PATIENTS AND METHODS:After having modified two items, we administered the Italian version of ...

journal_title：Neuropsychiatric disease and treatment

authors： Di Lorenzo R,Cabri G,Carretti E,Galli G,Giambalvo N,Rioli G,Saraceni S,Spiga G,Del Giovane C,Ferri P

更新日期：2017-01-23 00:00:00

abstract：:Ischemic stroke is one of the leading causes of brain disease, with high morbidity, disability, and mortality. MicroRNAs (miRNAs) have been identified as vital gene regulators in various types of human diseases. Accumulating evidence has suggested that aberrant expression of miRNAs play critical roles in the pathologi...

journal_title：Neuropsychiatric disease and treatment

authors： Yao S,Tang B,Li G,Fan R,Cao F

更新日期：2016-12-05 00:00:00

abstract：Purpose:The study aimed to analyze the incidence of postoperative delirium (POD) and associated risk factors after liver transplantation (LT). Patients and Methods:We identified and enrolled patients undergoing LT at the Second Xiangya Hospital, Central South University between August 2018 and May 2019. We abstracted ...

journal_title：Neuropsychiatric disease and treatment

authors： Chen J,Wang H,He Z,Li T

更新日期：2020-07-03 00:00:00

abstract：:Elevation of plasma inflammatory factors in major depressive disorder (MDD) has been repeatedly observed, but contradictory results have also been reported. Alteration of complement components in MDD may also contribute to the pathophysiology of MDD by participating in inflammation. The recent findings that complement...

journal_title：Neuropsychiatric disease and treatment

authors： Wei J,Liu Y,Zhao L,Yang X,Ni P,Wang Y,Li T,Ma X

更新日期：2017-12-20 00:00:00

abstract：Background:Intentional methanol intoxication (IMI) is an emerging public health issue in Asian countries, but few data are available in the literature on underlying psychiatric comorbidities in these suicide attempters. Patients and methods:We conducted a retrospective chart review on patients with methanol intoxicati...

journal_title：Neuropsychiatric disease and treatment

authors： Yang WS,Yen TH,Juang YY,Lee SH,Wang BH,Lee CP

更新日期：2019-01-31 00:00:00

abstract：:It is proposed that lithium's therapeutic effects occur indirectly by augmenting a cascade of protective "fail-safe" pathways pre-configured to activate in response to a dangerous low cell [Mg++] situation, eg, posttraumatic brain injury, alongside relative cell adenosine triphosphate depletion. Lithium activates cell...

journal_title：Neuropsychiatric disease and treatment

authors： van Woerkom AE

更新日期：2017-01-31 00:00:00

abstract：Aim:This meta-analysis aimed to assess the effect of high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) for the treatment of depression in patients with Parkinson's disease (PD). Methods:The design was a meta-analysis of randomized controlled trials (RCTs). The participants were patients with PD who...

journal_title：Neuropsychiatric disease and treatment

authors： Qin B,Chen H,Gao W,Zhao LB,Zhao MJ,Qin HX,Yang MX

更新日期：2018-01-11 00:00:00

abstract：:Natalizumab is a monoclonal antibody that acts as an α4 integrin antagonist to prevent leukocyte trafficking into the central nervous system. It is US Food and Drug Administration (FDA) approved for the treatment of relapsing-remitting multiple sclerosis (RRMS). Natalizumab demonstrated high efficacy in Phase III tria...

journal_title：Neuropsychiatric disease and treatment

authors： Brandstadter R,Katz Sand I

更新日期：2017-06-28 00:00:00

abstract：Background:Based on inconsistent sensory alterations demonstrated in cluster headache (CH), the aim of this study was to determine whether patients with CH develop sensory changes in the symptomatic side compared to the asymptomatic side. Methods:Quantitative sensory testing (QST), including pressure pain threshold (P...

journal_title：Neuropsychiatric disease and treatment

authors： Malo-Urriés M,Hidalgo-García C,Estébanez-de-Miguel E,Tricás-Moreno JM,Santos-Lasaosa S,Jahanshahi M

更新日期：2018-12-10 00:00:00

abstract：BACKGROUND:Although many generalized anxiety disorder (GAD) patients respond to the available pharmacological treatments, nearly half of them do not present the expected results. Besides, the side effects associated to some drugs have a negative impact on treatment adherence. Therefore, the aim of this review was to re...

journal_title：Neuropsychiatric disease and treatment

authors： Levitan MN,Papelbaum M,Nardi AE

更新日期：2015-05-05 00:00:00

abstract：:Tuberous sclerosis complex (TSC) is a relatively rare genetic disorder, affecting one in 6,000 births. Mammalian target of rapamycin (mTOR) inhibitors, such as everolimus, which have been previously used to prevent solid organ transplant rejection, augment anticancer treatment regimens, and prevent neovascularization ...

journal_title：Neuropsychiatric disease and treatment

authors： Capal JK,Franz DN

更新日期：2016-08-25 00:00:00

abstract：PURPOSE:The aim of this study was to ascertain the clinical characteristics of drug-induced sleep-related eating disorder (SRED). PATIENTS AND METHODS:We retrospectively reviewed the medical records of 30 patients with primary SRED (without any comorbid sleep disorders and who were not taking any possible causative me...

journal_title：Neuropsychiatric disease and treatment

authors： Komada Y,Takaesu Y,Matsui K,Nakamura M,Nishida S,Kanno M,Usui A,Inoue Y

更新日期：2016-05-26 00:00:00