Profile of agomelatine and its potential in the treatment of generalized anxiety disorder.

abstract：OBJECTIVES:Although bipolar disorder has been understood classically as a cyclic disease with full recovery between mood episodes, in the last decade, evidence has accumulated supporting progressive features. The clinical picture of advanced or end-stage bipolar disorder is heterogeneous with possible deficits in cogni...

journal_title：Neuropsychiatric disease and treatment

authors： Dols A,Krudop W,Möller C,Shulman K,Sajatovic M,Pijnenburg YA

更新日期：2016-09-07 00:00:00

abstract：Purpose:Cardiovascular and metabolic adverse events are costly to treat, and their incidence is increased amongst people with schizophrenia, with different rates observed for second-generation antipsychotics. To inform treatment choice, this study sought to estimate the lifetime costs associated with antipsychotic choi...

journal_title：Neuropsychiatric disease and treatment

authors： Kearns B,Cooper K,Cantrell A,Thomas C

更新日期：2021-01-20 00:00:00

abstract：BACKGROUND:The aim of this paper is to report maternal and neonatal outcomes in pregnant women treated with escitalopram during pregnancy and breastfeeding. METHODS:Women enrolled in the DEGRA Database at the Clinic of Affective Disorders in Pregnancy and Postpartum in Italy, treated during pregnancy with escitalopram...

journal_title：Neuropsychiatric disease and treatment

authors： Bellantuono C,Bozzi F,Orsolini L

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Approximately 30%-60% of adults diagnosed with bipolar disorder (BD) report onset between the ages 15 and 19 years; however, a correct diagnosis is often delayed by several years. Therefore, investigations of the early features of BD are important for adequately understanding the prodromal stages of the illn...

journal_title：Neuropsychiatric disease and treatment

authors： Goetz M,Novak T,Vesela M,Hlavka Z,Brunovsky M,Povazan M,Ptacek R,Sebela A

更新日期：2015-11-04 00:00:00

abstract：:Melatonin (n-acetyl-5-methoxy-tryptamine), a naturally occurring indole produced mainly by the pineal gland, is a well known antioxidant. Stroke (cerebral ischemia) is the second leading cause of death worldwide. To date, however, effective and safe treatment for stroke remains unavailable. Melatonin is both lipid- an...

journal_title：Neuropsychiatric disease and treatment

authors： Lin HW,Lee EJ

更新日期：2009-01-01 00:00:00

abstract：Purpose:Numerous preclinical studies have demonstrated the potential neuroprotective effects of N-acetylcysteine (NAC) in the treatment of brain ischemia. Accordingly, the present study aimed to assess the potential therapeutic effects of oral NAC in patients with acute ischemic stroke. Patients and Methods:In a rando...

journal_title：Neuropsychiatric disease and treatment

authors： Sabetghadam M,Mazdeh M,Abolfathi P,Mohammadi Y,Mehrpooya M

更新日期：2020-05-18 00:00:00

abstract：BACKGROUND:Electroconvulsive therapy (ECT) is commonly used to treat depression in older adults. Despite its efficacy in this regard, an associated increase in the risk of falls in this population is a downside of treatment. ECT research has focused on the incidence of falls, but its effect on balance and gait - intrin...

journal_title：Neuropsychiatric disease and treatment

authors： Plakiotis C,Barson F,Vengadasalam B,Haines TP,O'Connor DW

更新日期：2013-01-01 00:00:00

abstract：:Neuropsychiatric symptoms are common in older adults with dementia and can be associated with a rapid decline in cognitive and functional status. This article reviews the current literature supporting the use of atypical antipsychotic medications in this population. Among the currently available atypical antipsychotic...

journal_title：Neuropsychiatric disease and treatment

authors： Lee PE,Gill SS,Rochon P

更新日期：2006-12-01 00:00:00

abstract：Purpose:Dual diagnosis (DD) is the co-occurrence of both a mental illness and a substance use disorder (SUD). Lots of studies have analysed the integrated clinical approach, which involves both psychiatry and toxicology medical experts. The purpose of this study is to analyse the socio-demographic characteristics and t...

journal_title：Neuropsychiatric disease and treatment

authors： Milano G,Vergani HM,Cattedra S,Carrozzino R,Mattioli F,Robbiano L,Martelli A

更新日期：2019-12-18 00:00:00

abstract：Objective:Ser9Gly (rs6280) is a functional single-nucleotide polymorphism (SNP) in the dopamine receptor D3 (DRD3) gene that may be associated with schizophrenia. We performed a meta-analysis to determine whether Ser9Gly influences the risk of schizophrenia and examined the relationship between the Ser9Gly SNP and the ...

journal_title：Neuropsychiatric disease and treatment

authors： Qi XL,Xuan JF,Xing JX,Wang BJ,Yao J

更新日期：2017-11-23 00:00:00

abstract：Purpose:Whole-exome sequencing (WES) of multiplex families is a promising strategy for identifying causative variations for common diseases. To identify rare recessive risk variations for schizophrenia, we performed a WES study in a consanguineous family with affected siblings. We then performed follow-up sequencing of...

journal_title：Neuropsychiatric disease and treatment

authors： Igeta H,Watanabe Y,Morikawa R,Ikeda M,Otsuka I,Hoya S,Koizumi M,Egawa J,Hishimoto A,Iwata N,Someya T

更新日期：2019-08-19 00:00:00

abstract：Goal:The goal of this study was to explore the impact of self-stigma on the treatment outcomes in patients with anxiety disorders and to find possible mediators of this relationship. Method:Two hundred and nine patients with anxiety disorders, who were hospitalized in a psychotherapeutic department, attended the study...

journal_title：Neuropsychiatric disease and treatment

authors： Ociskova M,Prasko J,Vrbova K,Kasalova P,Holubova M,Grambal A,Machu K

更新日期：2018-01-26 00:00:00

abstract：Purpose:Stroke remains the primary cause of pain, suffering, and death in patients. One of the major thrusts in stroke therapy is to find an effective prevention strategy. Objectives of this study are to testify the neuro-protection effect of stigmasterol in ischemic/reperfusion injury model. Methods:The dosage-depend...

journal_title：Neuropsychiatric disease and treatment

authors： Sun J,Li X,Liu J,Pan X,Zhao Q

更新日期：2019-10-18 00:00:00

abstract：:Tourette's syndrome (TS) is a neurodevelopmental disorder that comprises vocal and motor tics associated with a high frequency of psychiatric comorbidities, which has an important impact on quality of life. The onset is mainly in childhood and the symptoms can either fade away or require pharmacological therapies asso...

journal_title：Neuropsychiatric disease and treatment

authors： Casagrande SCB,Cury RG,Alho EJL,Fonoff ET

更新日期：2019-04-29 00:00:00

abstract：:The history and present status of the definition, prevalence, neurobiology, and treatment of atypical depression (AD) is presented. The concept of AD has evolved through the years, and currently, in Diagnostic and Statistical Manual of Mental Disorders (DSM), Fifth Edition, the specifier of depressive episode with aty...

journal_title：Neuropsychiatric disease and treatment

authors： Łojko D,Rybakowski JK

更新日期：2017-09-20 00:00:00

abstract：Background:Alarming somatic symptoms, in particular, cardiovascular symptoms, are the characteristic feature of panic attacks. Increased cardiac mortality and morbidity have been found in these patients. Power spectral analysis of electrocardiogram R-R intervals is known to be a particularly successful tool in the dete...

journal_title：Neuropsychiatric disease and treatment

authors： Kotianova A,Kotian M,Slepecky M,Chupacova M,Prasko J,Tonhajzerova I

更新日期：2018-02-07 00:00:00

abstract：:Tourette syndrome (TS) is a neuropsychiatric disorder with typical onset in childhood and characterized by chronic occurrence of motor and vocal tics. The disorder can lead to serious impairments of both quality of life and psychosocial functioning, particularly for those individuals displaying complex tics. In such p...

journal_title：Neuropsychiatric disease and treatment

authors： Huys D,Hardenacke K,Poppe P,Bartsch C,Baskin B,Kuhn J

更新日期：2012-01-01 00:00:00

abstract：:Restless legs syndrome (RLS) is one of the commonest movement disorders affecting sleep and also daytime functioning. The prevalence may be 8%-10% of the white Caucasian population. The diagnosis is simple and is based on a well-validated clinical questionnaire, yet misdiagnosis is common and the condition remains und...

journal_title：Neuropsychiatric disease and treatment

authors： Byrne R,Sinha S,Chaudhuri KR

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:We aimed to investigate the current prevalence of sexual dysfunction (SD), mood, anxiety, and personality disorders in female patients with fibromyalgia (FM). METHODS:This case-control study involved 96 patients with FM and 94 healthy women. The SD diagnosis was based on a psychiatric interview in accordanc...

journal_title：Neuropsychiatric disease and treatment

authors： Kayhan F,Küçük A,Satan Y,İlgün E,Arslan Ş,İlik F

更新日期：2016-02-16 00:00:00

abstract：Purpose:Typically, the diagnosis of conversion motor disorder (CMD) is achieved by the exclusion of a wide range of organic illnesses rather than by applying positive criteria. New diagnostic criteria are highly needed in this scenario. The main aim of this study was to explore the use of behavioral features as an incl...

journal_title：Neuropsychiatric disease and treatment

authors： Pastore A,Pierri G,Fabio G,Ferramosca S,Gigante A,Superbo M,Pellicciari R,Margari F

更新日期：2018-05-18 00:00:00

abstract：Aim:This meta-analysis aimed to assess the effect of high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) for the treatment of depression in patients with Parkinson's disease (PD). Methods:The design was a meta-analysis of randomized controlled trials (RCTs). The participants were patients with PD who...

journal_title：Neuropsychiatric disease and treatment

authors： Qin B,Chen H,Gao W,Zhao LB,Zhao MJ,Qin HX,Yang MX

更新日期：2018-01-11 00:00:00

abstract：Aim:Cardiovascular risk factors are also risk factors for cognitive impairment. They have cumulative effect in target organ damage. The precise correlation between cardiovascular risk factors and cognitive impairment, as well as assessing the extent to which they may affect cognitive functioning, is difficult to ascert...

journal_title：Neuropsychiatric disease and treatment

authors： Yaneva-Sirakova T,Traykov L,Petrova J,Gruev I,Vassilev D

更新日期：2017-12-05 00:00:00

abstract：Purpose:Entropy analysis of resting-state functional magnetic resonance imaging (R-fMRI) has recently been adopted to characterize brain temporal dynamics in some neuropsychological or psychiatric diseases. Thalamus-related dysfunction might be a potential trait marker of major depressive disorder (MDD), but the abnorm...

journal_title：Neuropsychiatric disease and treatment

authors： Xue SW,Wang D,Tan Z,Wang Y,Lian Z,Sun Y,Hu X,Wang X,Zhou X

更新日期：2019-09-11 00:00:00

abstract：:Depression is a major psychiatric disorder. The standard treatment for depression is antidepressant medication, but the responses to antidepressant treatment are only partial, even poor, among 30%-45% of patients. Refractory depression is defined as depression that does not respond to antidepressant therapy after 4 we...

journal_title：Neuropsychiatric disease and treatment

authors： Chen SJ,Chang CH,Tsai HC,Chen ST,Lin CCh

更新日期：2013-01-01 00:00:00

abstract：:Transcranial magnetic stimulation is an increasingly popular FDA-approved treatment for resistant depression, migraines, and OCD. Research is also underway for its use in various other psychiatric and medical disorders. Although rare, seizures are a potential adverse event of TMS treatment. In this article, we discuss...

journal_title：Neuropsychiatric disease and treatment

authors： Stultz DJ,Osburn S,Burns T,Pawlowska-Wajswol S,Walton R

更新日期：2020-12-07 00:00:00

abstract：Objective:Impairments in emotion regulation, and more specifically in cognitive reappraisal, are thought to play a key role in the pathogenesis of anxiety disorders. However, the available evidence on such deficits is inconsistent. To further illustrate the neurobiological underpinnings of anxiety disorder, the present...

journal_title：Neuropsychiatric disease and treatment

authors： Wang HY,Zhang XX,Si CP,Xu Y,Liu Q,Bian HT,Zhang BW,Li XL,Yan ZR

更新日期：2018-05-09 00:00:00

abstract：:Quetiapine is an atypical antipsychotic agent which is also prescribed for delirium due to its anti-dopaminergic effects; aphasia is an unusual side effect associated with the drug. Here, we report the case of an 83-year-old woman who was prescribed quetiapine (50 mg per day) for delirium. Unexpected, global aphasia o...

journal_title：Neuropsychiatric disease and treatment

authors： Chien CF,Huang P,Hsieh SW

更新日期：2017-08-28 00:00:00

abstract：Purpose:This study examined the links between 24-hour activity patterns (specifically, amplitude and timing of wrist activity) and the persisting qualities of clinical antidepressant response to the glutamatergic modulator ketamine. Methods:Twenty-four-hour activity patterns were compared across 5 days of 24-hour acti...

journal_title：Neuropsychiatric disease and treatment

authors： Duncan WC Jr,Slonena EE,Hejazi NS,Brutsche N,Park LT,Henter ID,Ballard ED,Zarate CA Jr

更新日期：2018-10-16 00:00:00

abstract：BACKGROUND:Low-volume high-intensity interval training (HIIT) is emerging as a time-efficient exercise strategy for improving cardiorespiratory fitness and for controlling blood sugar levels and hypertension. In addition, patient acceptance of HIIT may improve adherence to exercise programs. This study evaluated the ef...

journal_title：Neuropsychiatric disease and treatment

authors： Wu MH,Lee CP,Hsu SC,Chang CM,Chen CY

更新日期：2015-05-25 00:00:00

abstract：OBJECTIVES:This article addresses the clinical role for ziprasidone used adjunctively with a mood stabilizer in maintenance treatment of bipolar disorder. This review also addresses the strengths and limitations of design features in adjunctive studies of second-generation antipsychotic drugs added to mood stabilizers....

journal_title：Neuropsychiatric disease and treatment

authors： Bowden CL

更新日期：2011-01-01 00:00:00