Profile of everolimus in the treatment of tuberous sclerosis complex: an evidence-based review of its place in therapy.

abstract：BACKGROUND:Anhedonia constitutes a coherent construct, with neural correlates and negative clinical impact, independent of depression. However, little is known about the neural correlates of anhedonia in stroke patients. In this study, we investigated the association of post-stroke anhedonia with salivary cortisol leve...

journal_title：Neuropsychiatric disease and treatment

authors： Terroni L,Amaro E Jr,Iosifescu DV,Mattos P,Yamamoto FI,Tinone G,Conforto AB,Sobreiro MF,Guajardo VD,De Lucia MC,Moreira AC,Scaff M,Leite CC,Fraguas R

更新日期：2015-02-03 00:00:00

abstract：:Headaches in children and adolescents are still under-diagnosed. 75% of children are affected by primary headache by the age of 15 with 28% fitting the ICHD2 criteria of migraine. Migraine is considered a chronic disorder that can severely impact a child's daily activities, including schooling and socializing. Early r...

journal_title：Neuropsychiatric disease and treatment

authors： Kabbouche MA,Gilman DK

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:The Dark Triad (DT) describes a set of three closely related personality traits: Machiavellianism, narcissism, and psychopathy. Mental toughness (MT) refers to a psychological construct combining confidence, commitment, control, and challenge. High MT is related to greater physical activity (PA) and, relative...

journal_title：Neuropsychiatric disease and treatment

authors： Sabouri S,Gerber M,Sadeghi Bahmani D,Lemola S,Clough PJ,Kalak N,Shamsi M,Holsboer-Trachsler E,Brand S

更新日期：2016-01-27 00:00:00

abstract：Objective:Our study aimed to estimate the frequency of inborn errors of metabolism (IEMs) in patients presenting with acute encephalopathy-like picture at an emergency department (ED). Subjects and methods:Our study was a prospective observational study conducted on 30 patients admitted to the pediatric ED with unexpl...

journal_title：Neuropsychiatric disease and treatment

authors： Abdel Maksoud M,ELsayed SM,Shatla RH,Imam AA,Elsayed RM,Mosabah AA,Sherif AM

更新日期：2018-06-29 00:00:00

abstract：Objective:Ser9Gly (rs6280) is a functional single-nucleotide polymorphism (SNP) in the dopamine receptor D3 (DRD3) gene that may be associated with schizophrenia. We performed a meta-analysis to determine whether Ser9Gly influences the risk of schizophrenia and examined the relationship between the Ser9Gly SNP and the ...

journal_title：Neuropsychiatric disease and treatment

authors： Qi XL,Xuan JF,Xing JX,Wang BJ,Yao J

更新日期：2017-11-23 00:00:00

abstract：:Prior studies have demonstrated the importance of treatment persistence with anti-psychotic agents in sustaining control of schizophrenic symptoms. However, the conventional approach in measuring treatment persistence tended to use only the first prescription episode even though some patients received multiple prescri...

journal_title：Neuropsychiatric disease and treatment

authors： Ren XS,Qian S,Kazis LE

更新日期：2007-04-01 00:00:00

abstract：Background:Displaced people experience different traumatic events. This can have serious and long-lasting consequences in terms of physical and mental health outcome. Post-traumatic stress disorder (PTSD) is the most frequent mental disorder following traumatic exposure. In 2018 Ethiopia saw the highest number of inter...

journal_title：Neuropsychiatric disease and treatment

authors： Madoro D,Kerebih H,Habtamu Y,G\/Tsadik M,Mokona H,Molla A,Wondie T,Yohannes K

更新日期：2020-10-07 00:00:00

abstract：BACKGROUND:Stroke has high mortality and morbidity. Biomarkers are required for to predict stroke outcomes, which could help clinicians to provide rationale approaches for patient management. The dynamic changes in circulating immune cells have been reported in stroke patients and animal models of stroke. AIM:The aim ...

journal_title：Neuropsychiatric disease and treatment

authors： Wang Y,Liu J,Wang X,Liu Z,Li F,Chen F,Geng X,Ji Z,Du H,Hu X

更新日期：2017-10-03 00:00:00

abstract：:A plethora of research has implicated hundreds of putative biomarkers for depression, but has not yet fully elucidated their roles in depressive illness or established what is abnormal in which patients and how biologic information can be used to enhance diagnosis, treatment and prognosis. This lack of progress is par...

journal_title：Neuropsychiatric disease and treatment

authors： Strawbridge R,Young AH,Cleare AJ

更新日期：2017-05-10 00:00:00

abstract：:This case report describes the detection of homonymous hemianopsia and delirium during the admission physical examination of a patient with esophageal adenocarcinoma, resulting in the new diagnosis of subacute hemorrhagic stroke. The poststroke visual field defect can result in significant disability and reduction in ...

journal_title：Neuropsychiatric disease and treatment

authors： Tsymbalov KS,Fetkenhour DR

更新日期：2016-06-15 00:00:00

abstract：:Obsessive compulsive and impulsive symptoms are prevalent in patients with Tourette's Syndrome (TS) and well recognized as part of the TS spectrum. However, some complex obsessive compulsive and impulsive behaviors may be mistaken for other symptoms, such as complex tics or psychotic behavior. In addition, the overlap...

journal_title：Neuropsychiatric disease and treatment

authors： Palumbo D,Kurlan R

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:There have not been any reports in Japan clarifying the efficacy and safety of intramuscular (IM) olanzapine and IM levomepromazine in agitated elderly patients with schizophrenia. This study was a comparative investigation of the clinical efficacy and safety of IM olanzapine and IM levomepromazine in agitat...

journal_title：Neuropsychiatric disease and treatment

authors： Suzuki H,Gen K

更新日期：2013-01-01 00:00:00

abstract：Purpose:Color preferences vary among normal individuals and psychiatric patients, and this might be related to their different levels of hypnotic susceptibility. We hypothesized that individuals with higher hypnotic susceptibility prefer more arousing colors such as red. Patients and methods:Out of 440 participants, w...

journal_title：Neuropsychiatric disease and treatment

authors： Yu E,Zhu J,Tan Y,Liao Z,Qiu Y,Zhang B,Wang C,Wang W

更新日期：2018-01-30 00:00:00

abstract：BACKGROUND:No study has examined the financial impact of relapses on schizophrenia from the perspective of Japanese society. This study aimed to estimate the societal costs in Japan caused by the relapses of schizophrenia. METHODS:The societal costs in Japan in 2013 due to relapses of schizophrenia were estimated by s...

journal_title：Neuropsychiatric disease and treatment

authors： Nakamura Y,Mahlich J

更新日期：2017-05-17 00:00:00

abstract：BACKGROUND:Metabolic syndrome (MetS) is one of the primary reasons for increased mortality in patients with schizophrenia. The mechanisms involved in its pathogenesis are not well understood. OBJECTIVE:To estimate the prevalence of MetS in adult outpatients with schizophrenia according to the presence or absence of ne...

journal_title：Neuropsychiatric disease and treatment

authors： Sicras-Mainar A,Maurino J,Ruiz-Beato E,Navarro-Artieda R

更新日期：2014-12-30 00:00:00

abstract：:Obsessive-compulsive disorder (OCD) is a chronic anxiety disorder. While medication and psychotherapy advances have been very helpful to patients, many patients do not respond adequately to initial trials of serotonergic medication or cognitive-behavioral therapy (CBT) and require multiple treatment trials or combinat...

journal_title：Neuropsychiatric disease and treatment

authors： Walsh KH,McDougle CJ

更新日期：2011-01-01 00:00:00

abstract：Background:Road traffic crashes (RTCs) can cause serious and long-lasting consequences for drivers, both in terms of physical and mental health outcomes. Posttraumatic stress disorder (PTSD) is the most frequent mental disorder occurring after traumatic exposure. Ethiopian drivers experience RTCs more frequently than o...

journal_title：Neuropsychiatric disease and treatment

authors： Alenko A,Berhanu H,Abera Tareke A,Reta W,Bariso M,Mulat E,Kenenisa C,Debebe W,Tolesa K,Girma S

更新日期：2019-12-24 00:00:00

abstract：:Abnormal prion proteins are responsible for several fatal neurodegenerative diseases in humans and in animals, including Creutzfeldt-Jakob disease (CJD), Gerstmann-Sträussler-Scheinker disease, and fatal familial insomnia. Genetics is important in prion diseases, but in the most cases, cause of diseases remained unkno...

journal_title：Neuropsychiatric disease and treatment

authors： Bagyinszky E,Giau VV,Youn YC,An SSA,Kim S

更新日期：2018-08-14 00:00:00

abstract：OBJECTIVE:To investigate the predictors of suicidal ideation and attempts among Turkish Parkinson's disease (PD) patients. MATERIALS AND METHODS:The study comprised 120 patients with PD. Clinical findings were obtained by using the Unified Parkinson's Disease Rating Scale. Disease severity was measured by the Hoehn an...

journal_title：Neuropsychiatric disease and treatment

authors： Ozdilek B,Gultekin BK

更新日期：2014-03-26 00:00:00

abstract：:Aripiprazole is a third generation atypical antipsychotic with compelling evidence as a highly effective treatment option in the management of acute manic and mixed episodes of bipolar I disorders. It has a unique mode of action, acting as a partial agonist at dopamine D2 and D3, and serotonin 5-HT1A; and exhibiting a...

journal_title：Neuropsychiatric disease and treatment

authors： Sayyaparaju KK,Grunze H,Fountoulakis KN

更新日期：2014-03-13 00:00:00

abstract：OBJECTIVE:The study aimed at exploring bereavement and complicated grief (CG) symptoms among subjects without a history of coronary heart disease (CHD) at the time of a first acute coronary syndrome (ACS) and to evaluate the relationship of CG symptoms and ACS. METHOD:Overall, 149 subjects with ACS (namely, acute myoc...

journal_title：Neuropsychiatric disease and treatment

authors： Pini S,Gesi C,Abelli M,Cardini A,Lari L,Felice F,Di Stefano R,Mazzotta G,Bovenzi F,Bertoli D,Borelli L,Michi P,Oligeri C,Balbarini A,Manicavasagar V

更新日期：2015-10-07 00:00:00

abstract：:Objective: To explore the efficacy and safety of "cocktail therapy" in Parkinson's disease with dementia (PDD). Patients and methods: Sixty patients with PDD were randomly assigned to the test group (n=30) and a control group (n=30). The control group received 10 mg of donepezil hydrochloride tablets orally, once a da...

journal_title：Neuropsychiatric disease and treatment

authors： Zhang C,Zang Y,Song Q,Li H,Hu L,Zhao W,Feng S,Gu F,Zhao F,Zhang C

更新日期：2019-06-24 00:00:00

abstract：:Stroke is one of the common causes of death and disability in the world. The intraluminal middle cerebral artery occlusion/reperfusion (MCAO/R) model is a "gold standard" in surgical ischemic stroke models. Here, we optimized the procedure of this model by ligating on external carotid artery (ECA) stump and two ligatu...

journal_title：Neuropsychiatric disease and treatment

authors： Cai Q,Xu G,Liu J,Wang L,Deng G,Liu J,Chen Z

更新日期：2016-11-03 00:00:00

abstract：INTRODUCTION:Essential tremor (ET) is the most common movement disorder in the adult population. At present ET treatment shows limited efficacy, particularly in patients with severe and disabling symptoms. This study evaluates the clinical efficacy of mirtazapine in an untreated ET patient population. MATERIALS AND ME...

journal_title：Neuropsychiatric disease and treatment

authors： Uccellini D,Grampa G,La Spina I,Nasuelli D,Neromante I,Politini L,Reverberi F,Porazzi D,Carli V,Camardese G

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Although many generalized anxiety disorder (GAD) patients respond to the available pharmacological treatments, nearly half of them do not present the expected results. Besides, the side effects associated to some drugs have a negative impact on treatment adherence. Therefore, the aim of this review was to re...

journal_title：Neuropsychiatric disease and treatment

authors： Levitan MN,Papelbaum M,Nardi AE

更新日期：2015-05-05 00:00:00

abstract：:Multiple Sclerosis (MS) is an inflammatory and neurodegenerative disease of the central nervous system, and both T and B cells are involved in its pathogenesis. The vast majority of disease-modifying drugs used for MS act on the inflammatory component of the disease and are approved for use in relapsing-remitting (RR)...

journal_title：Neuropsychiatric disease and treatment

authors： Frau J,Coghe G,Lorefice L,Fenu G,Cocco E

更新日期：2018-04-23 00:00:00

abstract：Purpose:Parkinson's disease (PD) is a common neurodegenerative movement disorder, but the pathogenesis remains elusive. This study was aimed to explore key genes and long noncoding RNAs (lncRNAs) associated with PD. Materials and methods:Three patients with PD and three normal controls were enrolled in the present stu...

journal_title：Neuropsychiatric disease and treatment

authors： Zhou Y,Gu C,Li J,Zhu L,Huang G,Dai J,Huang H

更新日期：2018-11-22 00:00:00

abstract：:To determine relationships between the need for dental treatments of institutionalized elderly people and cognitive impairment and the general level of care needed. Two hundred and sixty-eight residents of long-term care facilities in Germany were included in this study. Age, sex, diseases, number of frequently taken ...

journal_title：Neuropsychiatric disease and treatment

authors： Zenthöfer A,Rammelsberg P,Cabrera T,Hassel AJ

更新日期：2014-12-02 00:00:00

abstract：Background:Evidence has shown that microRNAs (miRNAs) are implicated in ischemic diseases. Therefore, the aim of the present study was to identify the functions of astrocyte (ATC)-derived exosomal miR-361 on cerebral ischemic-reperfusion (I/R) injury. Methods:A rat model of cerebral I/R injury was initially establishe...

journal_title：Neuropsychiatric disease and treatment

authors： Bu X,Li D,Wang F,Sun Q,Zhang Z

更新日期：2020-07-31 00:00:00

abstract：:Depression is a major psychiatric disorder. The standard treatment for depression is antidepressant medication, but the responses to antidepressant treatment are only partial, even poor, among 30%-45% of patients. Refractory depression is defined as depression that does not respond to antidepressant therapy after 4 we...

journal_title：Neuropsychiatric disease and treatment

authors： Chen SJ,Chang CH,Tsai HC,Chen ST,Lin CCh

更新日期：2013-01-01 00:00:00