Chemokines in the corpus luteum: implications of leukocyte chemotaxis.

abstract：:Establishment and maintenance of pregnancy in the pig involves intricate communication between the developing conceptuses and the maternal endometrium. This process occurs during trophoblast elongation which is spaciotemporally associated with conceptus synthesis and release of IL1B concomitant with pregnancy-specific...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Ross JW,Ashworth MD,Mathew D,Reagan P,Ritchey JW,Hayashi K,Spencer TE,Lucy M,Geisert RD

更新日期：2010-04-28 00:00:00

abstract：BACKGROUND:TGF-beta is a multifunctional growth factor involved in regulating a variety of cellular activities. Unlike mammals, the function of TGF-beta in the reproduction of lower vertebrates, such as fish, is not clear. Recently, we showed that TGF-beta1 inhibits gonadotropin- and 17alpha, 20beta-dihydroxyprogestero...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Kohli G,Clelland E,Peng C

更新日期：2005-09-30 00:00:00

abstract：BACKGROUND:Several medical conditions can affect and disrupt human sexuality. The alteration of sexuality in these medical conditions often hinder effective communication and empathy between the patients and their sexual partners because of cultural attitudes, social norms and negative feelings such as anxiety and guil...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Amidu N,Owiredu WK,Woode E,Appiah R,Quaye L,Gyasi-Sarpong CK

更新日期：2010-10-13 00:00:00

abstract：BACKGROUND:Methadone is the therapeutic agent of choice for the treatment of opiate addiction in pregnancy. The co-consumption (heroin, cocaine) which may influence the effects of methadone is frequent. Therefore, the impact of cocaine and heroin on the placental transfer of methadone and the placental tissue was inves...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Malek A,Obrist C,Wenzinger S,von Mandach U

更新日期：2009-06-11 00:00:00

abstract：BACKGROUND:Premutation range CGGn repeats of the FMR1 gene denote risk toward primary ovarian insufficiency (POI), also called premature ovarian failure (POF). This prospective cohort study was undertaken to determine if X-chromosome inactivation skew (sXCI) is associated with variations in FMR1 CGG repeat length and, ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Barad DH,Darmon S,Weghofer A,Latham GJ,Filipovic-Sadic,Wang Q,Kushnir VA,Albertini DF,Gleicher N

更新日期：2017-04-28 00:00:00

abstract：BACKGROUND:Doxorubicin is a potent chemotherapeutic drug used against a variety of cancers. It acts through interaction with polymerases and topoisomerase II and free radical production. Doxorubicin activity is not specific to cancer cells and can also damage healthy cells, especially those undergoing rapid proliferati...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Brilhante O,Okada FK,Sasso-Cerri E,Stumpp T,Miraglia SM

更新日期：2012-09-11 00:00:00

abstract：BACKGROUND:Serum leptin levels are augmented in obese infertile men and in men with azoospermia. They also correlate inversely with sperm concentration, motility and normal forms. The mechanisms underlying the adverse effects of excess leptin on male reproductive function remain unclear. The present study aimed to eval...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Wang X,Zhang X,Hu L,Li H

更新日期：2018-05-31 00:00:00

abstract：:Cloning by nuclear transfer using mammalian somatic cells has enormous potential application. However, somatic cloning has been inefficient in all species in which live clones have been produced. High abortion and fetal mortality rates are commonly observed. These developmental defects have been attributed to incomple...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Tian XC,Kubota C,Enright B,Yang X

更新日期：2003-11-13 00:00:00

abstract：BACKGROUND:Endocrine mechanisms governing canine reproductive function remain still obscure. Progesterone (P4) of luteal origin is required for maintenance of pregnancy. Corpora lutea (CL) are gonadotrop-independent during the first third of dioestrus; afterwards prolactin (PRL) is the primary luteotropic factor. Inter...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Kowalewski MP,Michel E,Gram A,Boos A,Guscetti F,Hoffmann B,Aslan S,Reichler I

更新日期：2011-08-03 00:00:00

abstract：BACKGROUND:Relaxin is detected in seminal plasma of many species and its association with sperm motility may be beneficial in some aspects of assisted reproduction. Here, we immunolocalized relaxin receptors and investigated the effects of exogenous relaxin on motility characteristics, viability, and cAMP content of bo...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Feugang JM,Rodríguez-Muñoz JC,Dillard DS,Crenshaw MA,Willard ST,Ryan PL

更新日期：2015-03-31 00:00:00

abstract：:A majority of common metabolic diseases can result in excessive lipolysis, leading to elevated levels of non-esterified fatty acids (NEFAs) in the body fluids. In females, increased NEFA levels in the follicular fluid markedly alter the functions of intrafollicular cells such as granulosa cells (GCs) and oocytes. Ther...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Baddela VS,Sharma A,Vanselow J

更新日期：2020-06-06 00:00:00

abstract：BACKGROUND:Prostaglandins are important for female reproduction. Prostaglandin-E2 acts via four different receptor subtypes, EP1, EP2, EP3 and EP4 whereas prostaglandin-F2alpha acts through FP. The functions of prostaglandins depend on the expression of their receptors in different uterine cell types. Our aim was to in...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Blesson CS,Büttner E,Masironi B,Sahlin L

更新日期：2012-01-18 00:00:00

abstract：BACKGROUND:The aim of this randomized controlled trial was to compare the efficacy of extended letrozole regimen with clomiphene citrate in women with unexplained infertility undergoing superovulation and intrauterine insemination (IUI). METHODS:Two hundred and fourteen patients with unexplained infertility were rando...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Fouda UM,Sayed AM

更新日期：2011-06-21 00:00:00

abstract：BACKGROUND:Despite significant advances in contraceptive options for women, vasectomy and condoms are the only options available for male contraception. Due to this limitation, the burden of contraception resides on the shoulders of females only. Therefore, there is an urgent need to develop a safe, effective and rever...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Chauhan A,Thaper D,Prabha V

更新日期：2020-09-30 00:00:00

abstract：BACKGROUND:Women with Polycystic Ovary Syndrome (PCOS) present a heterogeneous reproductive and metabolic profile with an increased lifetime risk of Type 2 Diabetes (T2D). Early biomarkers of these metabolic disturbances in PCOS women have not been identified. The abundance of circulating insulin gene promotor cell-fre...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Udesen PB,Sørensen AE,Joglekar MV,Hardikar AA,Wissing MLM,Englund AM,Dalgaard LT

更新日期：2019-04-05 00:00:00

abstract：BACKGROUND:Spermatic cord torsion can lead to testis ischemia (I) and subsequent ischemia-reperfusion (I/R) causing germ cell-specific apoptosis. Previously, we demonstrated that the hypoxia-inducible factor-1 (HIF-1) transcription factor, a key regulator of physiological responses to hypoxia, is abundant in Leydig cel...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Palladino MA,Shah A,Tyson R,Horvath J,Dugan C,Karpodinis M

更新日期：2012-12-05 00:00:00

abstract：BACKGROUND:Low functional ovarian reserve (LFOR) has been associated with hypoandrogenemia and increased embryo aneuploidy, while androgen supplementation has been reported to improve aneuploidy rates. We, therefore, assessed whether in infertile women undergoing in vitro fertilization (IVF) androgen concentrations are...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gleicher N,McCulloh DH,Kushnir VA,Ganguly N,Barad DH,Goldman KN,Kushnir MM,Albertini DF,Grifo JA

更新日期：2015-05-06 00:00:00

abstract：:Gonadotropins extracted from the urine of post-menopausal women have traditionally been used to stimulate folliculogenesis in the treatment of infertility and in assisted reproductive technology (ART). Products, such as human menopausal gonadotropin (hMG), consist not only of a mixture of the hormones, follicle-stimul...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Ezcurra D,Humaidan P

更新日期：2014-10-03 00:00:00

abstract：:Cloning mammals by nuclear transfer is a powerful technique that is quickly advancing the development of genetically defined animal models. However, the overall efficiency of nuclear transfer is still very low and several hurdles remain before the power of this technique will be fully harnessed. Among these hurdles in...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Li X,Li Z,Jouneau A,Zhou Q,Renard JP

更新日期：2003-11-07 00:00:00

abstract：BACKGROUND:Claudin-4 (CLDN4) is one of several proteins that act as molecular mediators of embryo implantation. Recently, we examined immunolabeling of leukemia inhibitory factor (LIF) in the endometrial tissue of 52 IVF patients, and found that LIF staining intensity was strongly correlated with successful pregnancy i...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Serafini PC,Silva ID,Smith GD,Motta EL,Rocha AM,Baracat EC

更新日期：2009-04-19 00:00:00

abstract：BACKGROUND:The study was designed to test the hypothesis that granulosa cell (GC) gene expression response differs between recombinant FSH and human menopausal gonadotropin (hMG) stimulation regimens. METHODS:Females < 35 years-old undergoing IVF for tubal or male factor infertility were prospectively randomized to on...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Brannian J,Eyster K,Mueller BA,Bietz MG,Hansen K

更新日期：2010-03-12 00:00:00

abstract：BACKGROUND:Secreted protein of Ly-6 domain 1 (SOLD1), a secretory-type member of the Ly-6 superfamily, is expressed in both fetal and maternal tissues throughout gestation. SOLD1 mRNA is expressed in the endometrium and in trophoblast mononucleate and binucleate cells, suggesting it plays an important role not only in ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Awad M,Koshi K,Kizaki K,Takahashi T,Hashizume K

更新日期：2014-06-21 00:00:00

abstract：BACKGROUND:The aim of this study was to explore the impact of endometrial thickness change after progesterone administration on pregnancy outcome in patients transferred with single frozen-thawed blastocyst. METHODS:This observational cohort study included a total of 3091 patients undergoing their first frozen-thawed ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Bu Z,Yang X,Song L,Kang B,Sun Y

更新日期：2019-11-25 00:00:00

abstract：:Although Calbindin-D9k (CaBP-9k), a cytosolic calcium binding protein which has calcium binding sites, is expressed in various tissues, i.e., intestine, uterus, and placenta, potential roles of this gene and its protein are not clearly understood. Uterine CaBP-9k may be involved in controlling myometrial activity rela...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Choi KC,Leung PC,Jeung EB

更新日期：2005-11-16 00:00:00

abstract：BACKGROUND:We examined the presence and function of tachykinins and the tachykinin-degrading enzymes neprilysin (NEP) and neprilysin-2 (NEP2) in human spermatozoa. METHODS:Freshly ejaculated semen was collected from forty-eight normozoospermic human donors. We analyzed the expression of substance P, neurokinin A, neur...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Pinto FM,Ravina CG,Subiran N,Cejudo-Román A,Fernández-Sánchez M,Irazusta J,Garrido N,Candenas L

更新日期：2010-08-26 00:00:00

abstract：BACKGROUND:The synthesis of sex steroids is controlled by several enzymes such as17α-hydroxylase cytochrome P450 (P450c17) catalyzing androgen synthesis and aromatase cytochrome P450 (P450arom) catalyzing estrogen synthesis, both of which must complex with the redox partner NADPH-cytochrome P450 oxidoreductase (CPR) fo...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Dos Santos AC,Conley AJ,de Oliveira MF,Oliveira GB,Viana DC,Assis Neto AC

更新日期：2017-04-24 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated that progestin-primed ovarian stimulation (PPOS) protocol was a feasible and efficient method in in vitro fertilization (IVF) cycle. However, its application in women with advanced age has not been determined yet. The purpose of this study was to investigate its efficacy in...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Peng Q,Cao X,Wang J,Wang L,Xu J,Ji X,Liu S,Zhu J,Dong X

更新日期：2019-11-09 00:00:00

abstract：BACKGROUND:This study was designed to determine whether small diameter needles for oocyte retrieval alter oocyte yields in patients undergoing IVF in comparison to standard large diameter needles. METHODS:We conducted a prospective pilot study of 21 consecutive favorable prognosis patients. In each patient one ovary w...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Kushnir VA,Kim A,Gleicher N,Barad DH

更新日期：2013-03-20 00:00:00

abstract：BACKGROUND:Pregnant women have high serum concentrations of sex steroid hormones, which are major regulators of paracrine and autocrine responses for many maternal and placental functions. The main purpose of this study was to compare patients with preeclampsia and patients with uncomplicated pregnancies in terms of se...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Lan KC,Lai YJ,Cheng HH,Tsai NC,Su YT,Tsai CC,Hsu TY

更新日期：2020-02-18 00:00:00

abstract：BACKGROUND:This study was aimed at screening out the potential key genes and pathways associated with gestational diabetes mellitus (GDM). METHODS:The GSE70493 dataset used for this study was obtained from the Gene Expression Omnibus database. Differentially expressed genes (DEGs) in the placental tissue of women with...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Wang Y,Yu H,Liu F,Song X

更新日期：2019-11-29 00:00:00