Association of skewed X-chromosome inactivation with FMR1 CGG repeat length and anti-Mullerian hormone levels: a cohort study.

abstract：BACKGROUND:Human uterine leiomyoma (fibroids; LYO) are the most common benign neoplasms in reproductive-aged women. Dysregulated extracellular matrix and irregular LYO reversion-inducing cysteine-rich protein with Kazal motifs (RECK) expression are thought to be mediated by aberrant microRNA (miR) expression. The relat...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Guan Y,Guo L,Zukerberg L,Rueda BR,Styer AK

更新日期：2016-08-17 00:00:00

abstract：BACKGROUND:Antagonists of growth hormone-releasing hormone (GHRH) are being developed for the treatment of various human cancers. METHODS:MTT assay was used to test the proliferation of SKOV3 and CaOV3. The splice variant expression of GHRH receptors was examined by RT-PCR. The expression of protein in signal pathway ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Guo J,Schally AV,Zarandi M,Varga J,Leung PC

更新日期：2010-05-28 00:00:00

abstract：BACKGROUND:The objectives of this study were to develop an easy and rapid method for measuring gene expression in a small number of cells by real-time PCR without RNA extraction and purification, and to use this method to determine more precisely IGF-I gene expression in the cumulus cells surrounding oocytes. METHODS:...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Kumamoto K,Wang H,Yamashiro H,Terada T

更新日期：2005-10-27 00:00:00

abstract：:Human spermatozoa generate low levels of reactive oxygen species in order to stimulate key events, such as tyrosine phosphorylation, associated with sperm capacitation. However, if the generation of these potentially pernicious oxygen metabolites becomes elevated for any reason, spermatozoa possess a limited capacity ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Baker MA,Aitken RJ

更新日期：2005-11-29 00:00:00

abstract：BACKGROUND:To assess the amount of variability in ovarian follicular growth rate and maximum follicular diameter related to different centers, women and cycles of the same women in a multicenter observational study of follicular growth. METHODS:Secondary analysis of a prospective cohort study from eight centers in Eur...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Mikolajczyk RT,Stanford JB,Ecochard R

更新日期：2008-12-10 00:00:00

abstract：BACKGROUND:To examine the effects of IVF, ICSI and FET, as well as in vitro culture, on the safety of offspring, this study was conducted from the perspective of genetic imprinting to investigate whether assisted reproductive technology would influence the parental and maternal imprinting genes. METHODS:Eighteen foetu...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Ji M,Wang X,Wu W,Guan Y,Liu J,Wang J,Liu W,Shen C

更新日期：2018-07-05 00:00:00

abstract：BACKGROUND:The E2F family of transcription factors is required for the activation or repression of differentially expressed gene programs during the cell cycle in normal and abnormal development of tissues. We previously determined that members of the retinoblastoma protein family that interacts with the E2F family are...

journal_title：Reproductive biology and endocrinology : RB&E

authors： El-Darwish KS,Parvinen M,Toppari J

更新日期：2006-12-05 00:00:00

abstract：:The endometrium undergoes cyclic remodelling throughout the menstrual cycle in preparation for embryo implantation which occurs in a short window during the mid-secretory phase. It is during this short 'receptive window' that the endometrial luminal epithelium acquires adhesive capacity permitting blastocysts firm adh...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Santos LL,Ling CK,Dimitriadis E

更新日期：2020-12-14 00:00:00

abstract：BACKGROUND:The objective was to determine the effect of prepartum diets supplemented with rolled canola seed (high in oleic acid) or sunflower seed (high in linoleic acid) on luteinizing hormone (LH) pulsatility and gonadotropin releasing hormone (GnRH)-induced LH release during early postpartum. METHODS:Thirty-one pr...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Salehi R,Colazo MG,Oba M,Ambrose DJ

更新日期：2015-07-03 00:00:00

abstract：BACKGROUND:Di(2-ethylhexyl) phthalate (DEHP) exposure reduces embryo implantations, increases embryonic loss, and decreases fetal body weights. However, whether it is associated with the alteration of luteal function remains unknown. Thus, our aim in this study was to explore the effect and mechanism of DEHP on luteal ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Guo M,Lai L,Zong T,Lin Y,Yang B,Zhang L,Li M,Kuang H

更新日期：2015-03-03 00:00:00

abstract：BACKGROUND:There is limited literature investigating the effects of body mass index (BMI) and androgen level on in vitro fertilization (IVF) outcomes with a gonadotropin-releasing hormone (GnRH)-antagonist protocol in polycystic ovary syndrome (PCOS). Androgen-related variation in the effect of body mass index (BMI) on...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Yang W,Yang R,Lin M,Yang Y,Song X,Zhang J,Yang S,Song Y,Li J,Pang T,Deng F,Zhang H,Wang Y,Li R,Jiao J

更新日期：2018-11-19 00:00:00

abstract：BACKGROUND:The World Health Organization (WHO) international body mass index (BMI) cut-off points defining pre-pregnancy BMI categories in the Institute of Medicine (IOM) guidelines are not directly applicable to Asians. We aimed to define the optimal gestational weight gain (GWG) for the Korean population based on Asi...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Choi SK,Lee G,Kim YH,Park IY,Ko HS,Shin JC

更新日期：2017-08-22 00:00:00

abstract：:Cloning by nuclear transfer using mammalian somatic cells has enormous potential application. However, somatic cloning has been inefficient in all species in which live clones have been produced. High abortion and fetal mortality rates are commonly observed. These developmental defects have been attributed to incomple...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Tian XC,Kubota C,Enright B,Yang X

更新日期：2003-11-13 00:00:00

abstract：BACKGROUND:Studies suggested that microRNAs influence cellular activities in the uterus including cell differentiation and embryo implantation. In assisted reproduction cycles, luteal phase support, given to improve endometrial characteristics and to facilitate the implantation process, has been a standard practice. Th...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zhao Y,Zacur H,Cheadle C,Ning N,Fan J,Vlahos NF

更新日期：2012-09-06 00:00:00

abstract：BACKGROUND:Spermatic cord torsion can lead to testis ischemia (I) and subsequent ischemia-reperfusion (I/R) causing germ cell-specific apoptosis. Previously, we demonstrated that the hypoxia-inducible factor-1 (HIF-1) transcription factor, a key regulator of physiological responses to hypoxia, is abundant in Leydig cel...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Palladino MA,Shah A,Tyson R,Horvath J,Dugan C,Karpodinis M

更新日期：2012-12-05 00:00:00

abstract：:The aim of this study was to analyse the multigenerational effects of para-nonylphenol (NP) and resveratrol (RES) on the body weight, organ weight and reproductive fitness of outbred CD-1 mice. The data indicate that in male mice, NP had an effect on the weight of selected reproductive organs and the kidneys in the pa...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Kyselova V,Peknicova J,Buckiova D,Boubelik M

更新日期：2003-03-24 00:00:00

abstract：:Human embryonic stem cells (hESC) have emerged as attractive candidates for cell-based therapies that are capable of restoring lost cell and tissue function. These unique cells are able to self-renew indefinitely and have the capacity to differentiate in to all three germ layers (ectoderm, endoderm and mesoderm). Harn...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Desai N,Rambhia P,Gishto A

更新日期：2015-02-22 00:00:00

abstract：:During the follicular phase of the primate menstrual cycle, a single follicle usually matures to the preovulatory stage and releases its oocyte for fertilization and the potential establishment of pregnancy. In assisted reproductive technology procedures, it is desirable to override the natural process of follicle sel...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zeleznik AJ

更新日期：2004-06-16 00:00:00

abstract：BACKGROUND:Prostaglandins are important for female reproduction. Prostaglandin-E2 acts via four different receptor subtypes, EP1, EP2, EP3 and EP4 whereas prostaglandin-F2alpha acts through FP. The functions of prostaglandins depend on the expression of their receptors in different uterine cell types. Our aim was to in...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Blesson CS,Büttner E,Masironi B,Sahlin L

更新日期：2012-01-18 00:00:00

abstract：BACKGROUND:Polycystic ovary syndrome (PCOS) has been recognized as a metabolic disorder, manifested by abdominal obesity, insulin resistance, dyslipidemia and hypertension. Pigment epithelium-derived factor (PEDF), a member of the serine protease inhibitor family, is a pleiotropic protein known for its antiangiogenic, ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Lecke SB,Morsch D,Spritzer PM

更新日期：2013-08-14 00:00:00

abstract：:Macaques are menstruating nonhuman primates that provide important animal models for studies of hormonal regulation in the uterus. In women and macaques the decline of progesterone (P) at the end of the cycle triggers endometrial expression of a variety of matrix metalloproteinase (MMP) enzymes that participate in tis...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Slayden OD,Brenner RM

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Sperm of poor quality can negatively affect embryo development to the blastocyst stage. The aim of this comparative prospective randomized study was to evaluate the role of an intracytoplasmic morphologically selected sperm injection (IMSI) in the same infertile couples included in the programme of intracyto...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Knez K,Zorn B,Tomazevic T,Vrtacnik-Bokal E,Virant-Klun I

更新日期：2011-08-29 00:00:00

abstract：BACKGROUND:We examined the presence and function of tachykinins and the tachykinin-degrading enzymes neprilysin (NEP) and neprilysin-2 (NEP2) in human spermatozoa. METHODS:Freshly ejaculated semen was collected from forty-eight normozoospermic human donors. We analyzed the expression of substance P, neurokinin A, neur...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Pinto FM,Ravina CG,Subiran N,Cejudo-Román A,Fernández-Sánchez M,Irazusta J,Garrido N,Candenas L

更新日期：2010-08-26 00:00:00

abstract：:Cloning mammals by nuclear transfer is a powerful technique that is quickly advancing the development of genetically defined animal models. However, the overall efficiency of nuclear transfer is still very low and several hurdles remain before the power of this technique will be fully harnessed. Among these hurdles in...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Li X,Li Z,Jouneau A,Zhou Q,Renard JP

更新日期：2003-11-07 00:00:00

abstract：BACKGROUND:Endometriosis is an estrogen dependent, inflammatory disorder occurring in 5-10% of reproductive-aged women. Women with endometriosis have a lower body mass index (BMI) and decreased body fat compared to those without the disease, yet few studies have focused on the metabolic abnormalities in adipose tissue ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zolbin MM,Mamillapalli R,Nematian SE,Goetz L,Taylor HS

更新日期：2019-04-15 00:00:00

abstract：BACKGROUND:Overweight and obese women have been shown to have an increased risk of recurrent miscarriage as well as other adverse reproductive outcomes, but it is yet unclear whether this is due to an effect on the endometrium, embryo or both. The current study employs proteomic analysis to examine for a potential endo...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Metwally M,Preece R,Thomas J,Ledger W,Li TC

更新日期：2014-08-05 00:00:00

abstract：:The aim of our research was to examine the ability of density gradient preparation BoviPure and swim up method on bull sperm separation and in vitro embryo production (IVP) systems. Frozen/thawed semen from six Simmental bulls was pooled and treated using both methods. The sperm motility, concentration, membrane activ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Samardzija M,Karadjole M,Getz I,Makek Z,Cergolj M,Dobranic T

更新日期：2006-11-13 00:00:00

abstract：BACKGROUND:Limitations in our current knowledge of normative physiologic changes in thyroid function during the periconception window narrow our ability to establish an optimal approach to screening and diagnosis of thyroid disease in pregnant women. The objective of this study was to characterize changes in thyroid fu...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Balthazar U,Steiner AZ

更新日期：2012-03-21 00:00:00

abstract：BACKGROUND:The purpose of this study was to test the hypothesis that menstruation is associated with a higher concentration of endometrial cells in peritoneal fluid(PF) and with increased white and red blood cell concentration in PF when compared to nonmenstrual phases of the cycle. METHODS:PF was obtained at laparosc...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Bokor A,Debrock S,Drijkoningen M,Goossens W,Fülöp V,D'Hooghe T

更新日期：2009-10-30 00:00:00

abstract：:Fertilin alpha (ADAM-1) and beta (ADAM-2) are integral membrane proteins of the ADAM family that form a fertilin complex involved in key steps of the sperm-oocyte membrane interaction. In the present work, we analyzed the presence of ADAM-1 and ADAM-2 mRNAs, the spermatozoa proteins' processing and their sub-cellular ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Fàbrega A,Guyonnet B,Dacheux JL,Gatti JL,Puigmulé M,Bonet S,Pinart E

更新日期：2011-06-30 00:00:00