The physiology of follicle selection.

abstract：BACKGROUND:Polo-like kinase 1 (Plk1), as a characteristic regulator in meiosis, organizes multiple biological events of cell division. Although Plk1 has been implicated in various functions in somatic cell mitotic processes, considerably less is known regarding its function during the transition from metaphase I (MI) t...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zhang Z,Chen C,Ma L,Yu Q,Li S,Abbasi B,Yang J,Rui R,Ju S

更新日期：2017-08-29 00:00:00

abstract：BACKGROUND:Puberty onset is a complex, organized biological process with multilevel regulation, and its physiopathological mechanisms are yet to be elucidated. RFRP-3, the mammalian ortholog to gonadotropin-inhibitory hormone, is implicated in inhibiting the synthesis and release of gonadotropin in mammals. However, it...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Han X,He Y,Zeng G,Wang Y,Sun W,Liu J,Sun Y,Yu J

更新日期：2017-05-02 00:00:00

abstract：BACKGROUND:The association of recombinant FSH plus recombinant LH in 2:1 ratio may be used not only to induce ovulation in anovulatory women with hypogonadotropic hypogonadism but also to achieve multiple follicular developments in human IVF. The aim of this analysis was to estimate the cost-effectiveness of Controlled...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Mennini FS,Marcellusi A,Viti R,Bini C,Carosso A,Revelli A,Benedetto C

更新日期：2018-07-18 00:00:00

abstract：BACKGROUND:Declining numbers of wild giant anteaters highlight the importance of sustainable captive populations. Unfortunately, captive reproductive management is limited by the lack of external physical indicators of female reproductive status and the aggressive behavior of males. We examined the endocrinology of the...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Knott KK,Roberts BM,Maly MA,Vance CK,Debeachaump J,Majors J,Riger P,Decaluwe H,Kouba AJ

更新日期：2013-08-27 00:00:00

abstract：BACKGROUND:Spermatozoa are extremely vulnerable to oxidative stress caused by the unbalance between concentrations of reactive oxygen species and antioxidant scavenging systems present inside the male reproductive tract. In spite of a large number of clinical studies that claimed the beneficial effects of antioxidant o...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Talevi R,Barbato V,Fiorentino I,Braun S,Longobardi S,Gualtieri R

更新日期：2013-08-16 00:00:00

abstract：BACKGROUND:Coordinated differentiation of the endometrial compartments in the second half of the menstrual cycle is a prerequisite for the establishment of pregnancy. Endometrial stromal cells (ESC) decidualize under the influence of ovarian progesterone to accommodate implantation of the blastocyst and support establi...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Samalecos A,Reimann K,Wittmann S,Schulte HM,Brosens JJ,Bamberger AM,Gellersen B

更新日期：2009-07-20 00:00:00

abstract：BACKGROUND:We characterized the spectrum and etiology of hypogonadism in a cohort of Prader-Willi syndrome (PWS) adolescents and adults. METHODS:Reproductive hormonal profiles and physical examination were performed on 19 males and 16 females ages 16-34 years with PWS. Gonadotropins, sex-steroids, inhibin B (INB) and ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gross-Tsur V,Hirsch HJ,Benarroch F,Eldar-Geva T

更新日期：2012-05-06 00:00:00

abstract：BACKGROUND:Polycystic ovary syndrome (PCOS) has been recognized as a metabolic disorder, manifested by abdominal obesity, insulin resistance, dyslipidemia and hypertension. Pigment epithelium-derived factor (PEDF), a member of the serine protease inhibitor family, is a pleiotropic protein known for its antiangiogenic, ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Lecke SB,Morsch D,Spritzer PM

更新日期：2013-08-14 00:00:00

abstract：:The aim of our research was to examine the ability of density gradient preparation BoviPure and swim up method on bull sperm separation and in vitro embryo production (IVP) systems. Frozen/thawed semen from six Simmental bulls was pooled and treated using both methods. The sperm motility, concentration, membrane activ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Samardzija M,Karadjole M,Getz I,Makek Z,Cergolj M,Dobranic T

更新日期：2006-11-13 00:00:00

abstract：BACKGROUND:In-situ hybridisation studies demonstrate that Notch receptors and ligands are expressed in granulosa cells (GCs) and in the theca layer vasculature of growing follicles. Notch signaling involves cell-to-cell interaction mediated by transmembrane receptors and ligands. This signaling pathway may represent a ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Jovanovic VP,Sauer CM,Shawber CJ,Gomez R,Wang X,Sauer MV,Kitajewski J,Zimmermann RC

更新日期：2013-05-15 00:00:00

abstract：BACKGROUND:We examined the presence and function of tachykinins and the tachykinin-degrading enzymes neprilysin (NEP) and neprilysin-2 (NEP2) in human spermatozoa. METHODS:Freshly ejaculated semen was collected from forty-eight normozoospermic human donors. We analyzed the expression of substance P, neurokinin A, neur...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Pinto FM,Ravina CG,Subiran N,Cejudo-Román A,Fernández-Sánchez M,Irazusta J,Garrido N,Candenas L

更新日期：2010-08-26 00:00:00

abstract：BACKGROUND:Seminal plasma serves as a natural reservoir of antioxidants. It helps to remove excessive formation of reactive oxygen species (ROS) and consequently, reduce oxidative stress. Proteomic profiling of seminal plasma proteins is important to understand the molecular mechanisms underlying oxidative stress and s...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Sharma R,Agarwal A,Mohanty G,Du Plessis SS,Gopalan B,Willard B,Yadav SP,Sabanegh E

更新日期：2013-09-03 00:00:00

abstract：BACKGROUND:Gonadal differentiation in the mammalian fetus involves a complex dose-dependent genetic network. Initiation and progression of fetal ovarian and testicular pathways are accompanied by dynamic expression patterns of thousands of genes. We postulate these expression patterns are regulated by small non-coding ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Torley KJ,da Silveira JC,Smith P,Anthony RV,Veeramachaneni DN,Winger QA,Bouma GJ

更新日期：2011-01-11 00:00:00

abstract：:Preimplantation embryo development involves four stages: fertilization, cell cleavage, morula and blastocyst formation. During these stages, maternal and zygotic epigenetic factors play crucial roles. The gene expression profile is changed dramatically, chromatin is modified and core histone elements undergo significa...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Shi L,Wu J

更新日期：2009-06-05 00:00:00

abstract：BACKGROUND:The objective was to determine the effect of prepartum diets supplemented with rolled canola seed (high in oleic acid) or sunflower seed (high in linoleic acid) on luteinizing hormone (LH) pulsatility and gonadotropin releasing hormone (GnRH)-induced LH release during early postpartum. METHODS:Thirty-one pr...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Salehi R,Colazo MG,Oba M,Ambrose DJ

更新日期：2015-07-03 00:00:00

abstract：BACKGROUND:Sperm of poor quality can negatively affect embryo development to the blastocyst stage. The aim of this comparative prospective randomized study was to evaluate the role of an intracytoplasmic morphologically selected sperm injection (IMSI) in the same infertile couples included in the programme of intracyto...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Knez K,Zorn B,Tomazevic T,Vrtacnik-Bokal E,Virant-Klun I

更新日期：2011-08-29 00:00:00

abstract：BACKGROUND:In animals, low levels of vitamin D are associated with estrus cycle disturbances, but there are virtually no human data. We examined the association of 25-hydroxyvitamin D (25(OH)D) (a biomarker for vitamin D status) with menstrual cycle characteristics. METHODS:Women aged 35-44 were randomly selected from...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Jukic AM,Steiner AZ,Baird DD

更新日期：2015-03-11 00:00:00

abstract：:Fertilin alpha (ADAM-1) and beta (ADAM-2) are integral membrane proteins of the ADAM family that form a fertilin complex involved in key steps of the sperm-oocyte membrane interaction. In the present work, we analyzed the presence of ADAM-1 and ADAM-2 mRNAs, the spermatozoa proteins' processing and their sub-cellular ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Fàbrega A,Guyonnet B,Dacheux JL,Gatti JL,Puigmulé M,Bonet S,Pinart E

更新日期：2011-06-30 00:00:00

abstract：OBJECTIVE:To assess the effectiveness and safety of omega-3 fatty acid for patients with PCOS. METHODS:In this meta-analysis, data from randomized controlled trials were obtained to assess the effects of omega-3 fatty acid versus placebo or western medicine in women with PCOS. The study's registration number is CRD420...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Yang K,Zeng L,Bao T,Ge J

更新日期：2018-03-27 00:00:00

abstract：BACKGROUND:Endocrine mechanisms governing canine reproductive function remain still obscure. Progesterone (P4) of luteal origin is required for maintenance of pregnancy. Corpora lutea (CL) are gonadotrop-independent during the first third of dioestrus; afterwards prolactin (PRL) is the primary luteotropic factor. Inter...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Kowalewski MP,Michel E,Gram A,Boos A,Guscetti F,Hoffmann B,Aslan S,Reichler I

更新日期：2011-08-03 00:00:00

abstract：BACKGROUND:Septate uterus, one of the most common forms of congenital uterine malformations, negatively affects female reproductive health. METHODS:In a retrospective cohort study, we evaluated the reproductive outcome after hysteroscopic septoplasty in 64 women with septate uterus and primary or secondary infertility...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Nouri K,Ott J,Huber JC,Fischer EM,Stögbauer L,Tempfer CB

更新日期：2010-05-21 00:00:00

abstract：BACKGROUND:There is limited literature investigating the effects of body mass index (BMI) and androgen level on in vitro fertilization (IVF) outcomes with a gonadotropin-releasing hormone (GnRH)-antagonist protocol in polycystic ovary syndrome (PCOS). Androgen-related variation in the effect of body mass index (BMI) on...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Yang W,Yang R,Lin M,Yang Y,Song X,Zhang J,Yang S,Song Y,Li J,Pang T,Deng F,Zhang H,Wang Y,Li R,Jiao J

更新日期：2018-11-19 00:00:00

abstract：BACKGROUND:Male factor infertility is quite common as 30-50% of infertility cases are due to sperm defects. The high sperm DNA fragmentation is one of the causes of male factor infertility. Many factors cause sperm DNA fragmentation and could be testicular or post-testicular. The purpose of this study was to assess rel...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Al Omrani B,Al Eisa N,Javed M,Al Ghedan M,Al Matrafi H,Al Sufyan H

更新日期：2018-05-19 00:00:00

abstract：BACKGROUND:Turkey reproduction is by artificial insemination using pooled semen so there is interest in storing semen. Fertilizing capacity declines after six hours storage, possibly due to poor sperm mobility. Prostaglandins (PG) affect mammalian sperm motility, but avian sperm has not been widely studied. For this st...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Kennedy JH,Korn N,Thurston RJ

更新日期：2003-10-09 00:00:00

abstract：BACKGROUND:During the estrous cycle, the rat uterine endometrium undergoes many changes such as cell proliferation and apoptosis. If implantation occurs, stromal cells differentiate into decidual cells and near the end of pregnancy, a second wave of apoptosis occurs. This process called decidual regression, is tightly ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Caron PL,Fréchette-Frigon G,Shooner C,Leblanc V,Asselin E

更新日期：2009-08-05 00:00:00

abstract：BACKGROUND:The aim of this study was to compare pregnancy rates in patients undergoing IVF/ICSI with embryo transfer after 4 and 5 days of culture in a closed incubation system with integrated time-lapse imaging. METHODS:Out of n = 2207 in vitro fertilization (IVF)/ intracytoplasmic sperm injection (ICSI) cycles perfo...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Holschbach V,Weigert J,Dietrich JE,Roesner S,Montag M,Strowitzki T,Toth B

更新日期：2017-05-08 00:00:00

abstract：BACKGROUND:The aim of this randomized controlled trial was to compare the efficacy of extended letrozole regimen with clomiphene citrate in women with unexplained infertility undergoing superovulation and intrauterine insemination (IUI). METHODS:Two hundred and fourteen patients with unexplained infertility were rando...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Fouda UM,Sayed AM

更新日期：2011-06-21 00:00:00

abstract：:The adaptive immune system of placental mammals has evolved to tolerate the fetus. Rejection of the fetus by adaptive immune responses is therefore a rare event, with abortion being caused more frequently by inflammation in the placenta. This review will cover recent aspects of immune privilege and the innate immune s...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Kanellopoulos-Langevin C,Caucheteux SM,Verbeke P,Ojcius DM

更新日期：2003-12-02 00:00:00

abstract：BACKGROUND:Implantation of the embryo and successful pregnancy are dependent on the differentiation of endometrial stromal cells into decidual cells. Female interleukin-11 receptor alpha (IL-11Ralpha) deficient mice are infertile due to disrupted decidualization, suggesting a critical role for IL-11 and its target gene...

journal_title：Reproductive biology and endocrinology : RB&E

authors： White CA,Robb L,Salamonsen LA

更新日期：2004-11-10 00:00:00

abstract：BACKGROUND:Morphological aspect of polycystic ovaries (PCO) is a very common finding in an IVF center population: this includes PCOS patients identified in 18-25% of the couples presenting with infertility and so called "sonographic PCO only" the prevalence of which has been estimated as high as 33% in asymptomatic pat...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Decanter C,Robin G,Thomas P,Leroy M,Lefebvre C,Soudan B,Lefebvre-Khalil V,Leroy-Martin B,Dewailly D

更新日期：2013-06-19 00:00:00