Protective effects of in vitro treatment with zinc, d-aspartate and coenzyme q10 on human sperm motility, lipid peroxidation and DNA fragmentation.

abstract：BACKGROUND:Age at menarche is the reflection of cumulative pre-adolescent exposure of girls to either adverse environment such as food insecurity or affluent living conditions. Food insecurity could result in inadequate nutrient intake and stress, both of which are hypothesized to have opposing effects on the timing of...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Belachew T,Hadley C,Lindstrom D,Getachew Y,Duchateau L,Kolsteren P

更新日期：2011-09-13 00:00:00

abstract：BACKGROUND:Alpha 2 macroglobulin (A2M; also known as ovostatin), a homotetrameric protein with four disulfide-linked subunits, has the unique feature of inactivating/inhibiting most known proteases including serine-, threonine-, cysteine-, aspartic- and metalloproteases. In chickens, A2M has been identified and charact...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Lim W,Jeong W,Kim JH,Lee JY,Kim J,Bazer FW,Han JY,Song G

更新日期：2011-10-07 00:00:00

abstract：BACKGROUND:The objective of this study was to identify substantially increased proteins in bovine cystic follicular fluid (FF) in order to clarify the pathology and etiology of bovine ovarian follicular cysts (BOFC). METHODS:Proteins in normal and cystic FF samples were subjected to two-dimensional polyacrylamide gel ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Maniwa J,Izumi S,Isobe N,Terada T

更新日期：2005-06-08 00:00:00

abstract：BACKGROUND:Polycystic Ovary Syndrome (PCOS) is the most common gynecological endocrinopathy in women of reproductive age. Despite its heavy burden on female reproduction and general health, there is no study regarding PCOS prevalence in Palestine. This study aims to establish prevalence of PCOS among female university ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Musmar S,Afaneh A,Mo'alla H

更新日期：2013-05-20 00:00:00

abstract：BACKGROUND:Mammalian oocyte meiotic maturation involves a number of important processes, including spindle assembly and migration, cortical reorganization and polar body extrusion. Numerous proteins contribute to these processes, but it is unknown whether MKlp2 (mitotic kinesin-like protein 2; also called KIF20A), a mi...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Liu J,Wang QC,Cui XS,Wang ZB,Kim NH,Sun SC

更新日期：2013-12-21 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) is a common endocrine disorder, affecting 9-18% of women in reproductive age that causes hyperandrogenism and infertility due to dysfunctional follicular maturation and anovulation. The etiology of PCOS is still poorly known, and information from experimental animal models may help imp...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Paixão L,Ramos RB,Lavarda A,Morsh DM,Spritzer PM

更新日期：2017-02-10 00:00:00

abstract：BACKGROUND:Pregnancy-associated plasma protein-A2 (PAPP-A2) is consistently upregulated in the placentae of pregnancies complicated by preeclampsia and fetal growth restriction. The causes and significance of this upregulation remain unknown, but it has been hypothesized that it is a compensatory response to improve pl...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Christians JK,Lennie KI,Huicochea Munoz MF,Binning N

更新日期：2018-06-12 00:00:00

abstract：BACKGROUND:Despite the clinical outcomes of ovarian stimulation with either GnRH-agonist or GnRH-antagonist analogues for in vitro fertilization (IVF) being well analysed, the effect of analogues on oocyte/embryo quality and embryo development is still not known in detail. The aim of this case-control study was to comp...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Murber A,Fancsovits P,Ledó N,Gilán ZT,Rigó J Jr,Urbancsek J

更新日期：2009-09-25 00:00:00

abstract：BACKGROUND:There is limited literature investigating the effects of body mass index (BMI) and androgen level on in vitro fertilization (IVF) outcomes with a gonadotropin-releasing hormone (GnRH)-antagonist protocol in polycystic ovary syndrome (PCOS). Androgen-related variation in the effect of body mass index (BMI) on...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Yang W,Yang R,Lin M,Yang Y,Song X,Zhang J,Yang S,Song Y,Li J,Pang T,Deng F,Zhang H,Wang Y,Li R,Jiao J

更新日期：2018-11-19 00:00:00

abstract：BACKGROUND:Antagonists of growth hormone-releasing hormone (GHRH) are being developed for the treatment of various human cancers. METHODS:MTT assay was used to test the proliferation of SKOV3 and CaOV3. The splice variant expression of GHRH receptors was examined by RT-PCR. The expression of protein in signal pathway ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Guo J,Schally AV,Zarandi M,Varga J,Leung PC

更新日期：2010-05-28 00:00:00

abstract：BACKGROUND:hCG is a term referring to 4 independent molecules, each produced by separate cells and each having completely separate functions. These are hCG produced by villous syncytiotrophoblast cells, hyperglycosylated hCG produced by cytotrophoblast cells, free beta-subunit made by multiple primary non-trophoblastic...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Cole LA

更新日期：2010-08-24 00:00:00

abstract：BACKGROUND:Hyperandrogenic conditions have been associated with a high prevalence of endometrial pathologies related to cell survival. However, the action of androgens on proliferation and apoptosis in endometrial cells is poorly understood. Therefore, the aim of the present study was to evaluate the effect of androste...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Maliqueo MA,Quezada S,Clementi M,Bacallao K,Anido M,Johnson C,Vega M

更新日期：2004-12-10 00:00:00

abstract：BACKGROUND:The association of recombinant FSH plus recombinant LH in 2:1 ratio may be used not only to induce ovulation in anovulatory women with hypogonadotropic hypogonadism but also to achieve multiple follicular developments in human IVF. The aim of this analysis was to estimate the cost-effectiveness of Controlled...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Mennini FS,Marcellusi A,Viti R,Bini C,Carosso A,Revelli A,Benedetto C

更新日期：2018-07-18 00:00:00

abstract：BACKGROUND:In-situ hybridisation studies demonstrate that Notch receptors and ligands are expressed in granulosa cells (GCs) and in the theca layer vasculature of growing follicles. Notch signaling involves cell-to-cell interaction mediated by transmembrane receptors and ligands. This signaling pathway may represent a ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Jovanovic VP,Sauer CM,Shawber CJ,Gomez R,Wang X,Sauer MV,Kitajewski J,Zimmermann RC

更新日期：2013-05-15 00:00:00

abstract：:Macaques are menstruating nonhuman primates that provide important animal models for studies of hormonal regulation in the uterus. In women and macaques the decline of progesterone (P) at the end of the cycle triggers endometrial expression of a variety of matrix metalloproteinase (MMP) enzymes that participate in tis...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Slayden OD,Brenner RM

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:The injection of estradiol valerate in female rats induces polycystic ovary syndrome, which is characterized by polycystic ovaries, anovulation, and hyperandrogenism. These characteristics have been associated with an increase in the ovarian concentration of norepinephrine, which occurs before establishing t...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Espinoza JA,Alvarado W,Venegas B,Domínguez R,Morales-Ledesma L

更新日期：2018-09-07 00:00:00

abstract：:LINE1 retrotransposons are mobile DNA elements that copy and paste themselves into new sites in the genome. To ensure their evolutionary success, heritable new LINE-1 insertions accumulate in cells that can transmit genetic information to the next generation (i.e., germ cells and embryonic stem cells). It is our hypot...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Lou C,Goodier JL,Qiang R

更新日期：2020-01-21 00:00:00

abstract：BACKGROUND:Infertile men have higher levels of semen reactive oxygen species (ROS) than fertile men. High levels of semen ROS can cause sperm dysfunction, sperm DNA damage and reduced male reproductive potential. This study investigated the effects of supplementation with N-acetyl-cysteine (NAC) on the sperm quality, c...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Jannatifar R,Parivar K,Roodbari NH,Nasr-Esfahani MH

更新日期：2019-02-16 00:00:00

abstract：BACKGROUND:The Rapid-i is a new FDA cleared closed carrier for embryo vitrification. The cooling rate of - 1220°C/min is far lower than that reported with open vitrification systems such as the cryoloop (-15,000°C/min). Little published data is currently available on this device. This study presents our initial clinica...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Desai NN,Goldberg JM,Austin C,Falcone T

更新日期：2013-05-15 00:00:00

abstract：BACKGROUND:Estradiol (E2) and progesterone (P) are well known regulators of progesterone receptor (PR) expression in the rat uterus. However, it is not known which receptor subtypes are involved. Little knowledge exist about possible differences in PR regulation through ERalpha or ERbeta, and whether the PR subtypes ar...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Sahlin L,Masironi B,Akerberg S,Eriksson H

更新日期：2006-09-11 00:00:00

abstract：:The corpus luteum is an endocrine gland whose limited lifespan is hormonally programmed. This debate article summarizes findings of our research group that challenge the principle that the end of function of the corpus luteum or luteal regression, once triggered, cannot be reversed. Overturning luteal regression by ph...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Telleria CM

更新日期：2006-10-30 00:00:00

abstract：BACKGROUND:High levels of dopamine (DA) were described in human ovary and recently evidence for DA receptors in granulosa and luteal cells has been provided, as well. However, neither the full repertoire of ovarian receptors for DA, nor their specific role, is established. Human granulosa cells (GCs) derived from women...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Rey-Ares V,Lazarov N,Berg D,Berg U,Kunz L,Mayerhofer A

更新日期：2007-10-25 00:00:00

abstract：:The prolonged lockdown of health services providing high-complexity fertility treatments -as currently recommended by many reproductive medicine entities- is detrimental for society as a whole, and infertility patients in particular. Globally, approximately 0.3% of all infants born every year are conceived using assis...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Alviggi C,Esteves SC,Orvieto R,Conforti A,La Marca A,Fischer R,Andersen CY,Bühler K,Sunkara SK,Polyzos NP,Strina I,Carbone L,Bento FC,Galliano D,Yarali H,Vuong LN,Grynberg M,Drakopoulos P,Xavier P,Llacer J,Neuspil

更新日期：2020-05-13 00:00:00

abstract：BACKGROUND:We examined the presence and function of tachykinins and the tachykinin-degrading enzymes neprilysin (NEP) and neprilysin-2 (NEP2) in human spermatozoa. METHODS:Freshly ejaculated semen was collected from forty-eight normozoospermic human donors. We analyzed the expression of substance P, neurokinin A, neur...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Pinto FM,Ravina CG,Subiran N,Cejudo-Román A,Fernández-Sánchez M,Irazusta J,Garrido N,Candenas L

更新日期：2010-08-26 00:00:00

abstract：BACKGROUND:In several species, considerably higher levels of estradiol-17 (E2) are synthesized in the CL. E2 has been suggested to participate in the regulation of luteal steroidogenesis and luteal cell morphology. In pregnant rats, several experiments have been carried out to examine the effects of inhibition of lutea...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Tripathy S,Asaithambi K,Jayaram P,Medhamurthy R

更新日期：2016-04-12 00:00:00

abstract：BACKGROUND:Seminal plasma serves as a natural reservoir of antioxidants. It helps to remove excessive formation of reactive oxygen species (ROS) and consequently, reduce oxidative stress. Proteomic profiling of seminal plasma proteins is important to understand the molecular mechanisms underlying oxidative stress and s...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Sharma R,Agarwal A,Mohanty G,Du Plessis SS,Gopalan B,Willard B,Yadav SP,Sabanegh E

更新日期：2013-09-03 00:00:00

abstract：BACKGROUND:Relaxin levels in seminal plasma have been associated with positive effects on sperm motility and quality, and thus having potential roles in male fertility. However, the origin of seminal relaxin, within the male reproductive tract, and the moment of its release in the vicinity of spermatozoa remain unclear...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Feugang JM,Greene JM,Sanchez-Rodríguez HL,Stokes JV,Crenshaw MA,Willard ST,Ryan PL

更新日期：2015-05-20 00:00:00

abstract：BACKGROUND:Mares have an annual reproductive rhythm, with a phase of inactivity in midwinter. The aim of this study was to determine the impact of food restriction on physiological and metabolic hallmarks of this rhythm. METHODS:Over three successive years, 3 groups of 10 mares were kept under natural photoperiod. A '...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Salazar-Ortiz J,Camous S,Briant C,Lardic L,Chesneau D,Guillaume D

更新日期：2011-09-29 00:00:00

abstract：BACKGROUND:Anti-thyroid antibodies (ATA), even if not associated with thyroid dysfunction, are suspected to cause poorer outcome of in vitro fertilization (IVF). METHODS:We retrospectively analyzed: (a) the prevalence of ATA in euthyroid infertile women, (b) IVF outcome in euthyroid, ATA+ patients, and (c) the effect ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Revelli A,Casano S,Piane LD,Grassi G,Gennarelli G,Guidetti D,Massobrio M

更新日期：2009-11-27 00:00:00

abstract：:Human spermatozoa generate low levels of reactive oxygen species in order to stimulate key events, such as tyrosine phosphorylation, associated with sperm capacitation. However, if the generation of these potentially pernicious oxygen metabolites becomes elevated for any reason, spermatozoa possess a limited capacity ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Baker MA,Aitken RJ

更新日期：2005-11-29 00:00:00