MKlp2 inhibitor paprotrain affects polar body extrusion during mouse oocyte maturation.

abstract：BACKGROUND:Secreted protein of Ly-6 domain 1 (SOLD1), a secretory-type member of the Ly-6 superfamily, is expressed in both fetal and maternal tissues throughout gestation. SOLD1 mRNA is expressed in the endometrium and in trophoblast mononucleate and binucleate cells, suggesting it plays an important role not only in ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Awad M,Koshi K,Kizaki K,Takahashi T,Hashizume K

更新日期：2014-06-21 00:00:00

abstract：OBJECTIVES:It is essential to understand the molecular basis of ovarian cancer etiology and tumor development to provide more effective preventive and therapeutic approaches to reduce mortality. Particularly, the molecular targets and pathways involved in early malignant transformation are still not clear. Pro-inflamma...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zhang L,Wang D,Jiang W,Edwards D,Qiu W,Barroilhet LM,Rho JH,Jin L,Seethappan V,Vitonis A,Wang J,Mok SC,Crum C,Cramer DW,Ye B

更新日期：2010-06-24 00:00:00

abstract：BACKGROUND:Male factor infertility is quite common as 30-50% of infertility cases are due to sperm defects. The high sperm DNA fragmentation is one of the causes of male factor infertility. Many factors cause sperm DNA fragmentation and could be testicular or post-testicular. The purpose of this study was to assess rel...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Al Omrani B,Al Eisa N,Javed M,Al Ghedan M,Al Matrafi H,Al Sufyan H

更新日期：2018-05-19 00:00:00

abstract：BACKGROUND:ATF6α, one of the sensor proteins in the stress signaling pathway of the endoplasmic reticulum, is located in the membrane of the endoplasmic reticulum. To date, the physiological function of ATF6α in the process of embryo implantation has not been reported. METHODS:In this study, the expression pattern of ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Xiong Y,Li W,Lin P,Wang L,Wang N,Chen F,Li X,Wang A,Jin Y

更新日期：2016-10-07 00:00:00

abstract：BACKGROUND:Previous caesarean scar pregnancy is one type of ectopic pregnancy in myometrium and fibrous tissue of previous caesarean scar. One of the therapeutic methods of this type of ectopic pregnancy is treatment with methotrexate. Given various findings on the treatment of caesarean scar pregnancy with methotrexat...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Salari N,Kazeminia M,Shohaimi S,Nankali AA,Mohammadi M

更新日期：2020-11-09 00:00:00

abstract：BACKGROUND:Serum leptin levels are augmented in obese infertile men and in men with azoospermia. They also correlate inversely with sperm concentration, motility and normal forms. The mechanisms underlying the adverse effects of excess leptin on male reproductive function remain unclear. The present study aimed to eval...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Wang X,Zhang X,Hu L,Li H

更新日期：2018-05-31 00:00:00

abstract：BACKGROUND:Adults with polycystic ovary syndrome (PCOS) can have multiple metabolic abnormalities. However, studies in the adolescent population are still limited and these results seem to vary widely. This study was to investigate the metabolic abnormalities in adolescents with PCOS in South China and the potential ri...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Huang J,Ni R,Chen X,Huang L,Mo Y,Yang D

更新日期：2010-11-17 00:00:00

abstract：BACKGROUND:The aim of this study was to determine the relationship between a purported luteinizing hormone/chorionic gonadotropin (LHCGR) high function polymorphism (rs4539842/insLQ) and outcome to controlled ovarian hyperstimulation (COH). METHODS:This was a prospective study of 172 patients undergoing COH at the Fer...

journal_title：Reproductive biology and endocrinology : RB&E

authors： O'Brien TJ,Kalmin MM,Harralson AF,Clark AM,Gindoff I,Simmens SJ,Frankfurter D,Gindoff P

更新日期：2013-07-25 00:00:00

abstract：BACKGROUND:Morphological aspect of polycystic ovaries (PCO) is a very common finding in an IVF center population: this includes PCOS patients identified in 18-25% of the couples presenting with infertility and so called "sonographic PCO only" the prevalence of which has been estimated as high as 33% in asymptomatic pat...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Decanter C,Robin G,Thomas P,Leroy M,Lefebvre C,Soudan B,Lefebvre-Khalil V,Leroy-Martin B,Dewailly D

更新日期：2013-06-19 00:00:00

abstract：BACKGROUND:Relaxin is detected in seminal plasma of many species and its association with sperm motility may be beneficial in some aspects of assisted reproduction. Here, we immunolocalized relaxin receptors and investigated the effects of exogenous relaxin on motility characteristics, viability, and cAMP content of bo...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Feugang JM,Rodríguez-Muñoz JC,Dillard DS,Crenshaw MA,Willard ST,Ryan PL

更新日期：2015-03-31 00:00:00

abstract：:Although Calbindin-D9k (CaBP-9k), a cytosolic calcium binding protein which has calcium binding sites, is expressed in various tissues, i.e., intestine, uterus, and placenta, potential roles of this gene and its protein are not clearly understood. Uterine CaBP-9k may be involved in controlling myometrial activity rela...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Choi KC,Leung PC,Jeung EB

更新日期：2005-11-16 00:00:00

abstract：:The corpus luteum is an endocrine gland whose limited lifespan is hormonally programmed. This debate article summarizes findings of our research group that challenge the principle that the end of function of the corpus luteum or luteal regression, once triggered, cannot be reversed. Overturning luteal regression by ph...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Telleria CM

更新日期：2006-10-30 00:00:00

abstract：BACKGROUND:The association of recombinant FSH plus recombinant LH in 2:1 ratio may be used not only to induce ovulation in anovulatory women with hypogonadotropic hypogonadism but also to achieve multiple follicular developments in human IVF. The aim of this analysis was to estimate the cost-effectiveness of Controlled...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Mennini FS,Marcellusi A,Viti R,Bini C,Carosso A,Revelli A,Benedetto C

更新日期：2018-07-18 00:00:00

abstract：BACKGROUND:In assisted reproductive technology, prediction of treatment failure remains a great challenge. The development of more sensitive assays for measuring anti-Müllerian hormone (AMH) has allowed for the possibility to investigate if a lower threshold of AMH can be established predicting very limited or no respo...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Grynnerup AG,Løssl K,Pilsgaard F,Lunding SA,Storgaard M,Bogstad JW,Prætorius L,Zedeler A,Bungum L,Nyboe Andersen A,Pinborg A

更新日期：2019-01-11 00:00:00

abstract：BACKGROUND:Peripheral and uterine natural killer cells (pNK and uNK cells) are key players in the establishment and maintenance of pregnancy and are disturbed in patients with recurrent miscarriage (RM). Different immunologic risk factors have been proposed between patients with primary RM (pRM, no previous live birth)...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Toth B,Vomstein K,Togawa R,Böttcher B,Hudalla H,Strowitzki T,Daniel V,Kuon RJ

更新日期：2019-08-31 00:00:00

abstract：BACKGROUND:The objective of this study was to identify substantially increased proteins in bovine cystic follicular fluid (FF) in order to clarify the pathology and etiology of bovine ovarian follicular cysts (BOFC). METHODS:Proteins in normal and cystic FF samples were subjected to two-dimensional polyacrylamide gel ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Maniwa J,Izumi S,Isobe N,Terada T

更新日期：2005-06-08 00:00:00

abstract：BACKGROUND:The placenta is an essential organ that provides nutrients and oxygen to the developing fetus and removes toxic waste products from the fetal circulation. Maintaining placental blood osmotic pressure and blood flow is crucial for viable offspring. The renin-angiotensin system (RAS) in the placenta is a key p...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Vaswani K,Chan HW,Verma P,Dekker Nitert M,Peiris HN,Wood-Bradley RJ,Armitage JA,Rice GE,Mitchell MD

更新日期：2015-08-12 00:00:00

abstract：BACKGROUND:Oocyte donation is a medical technique used principally for woman with ovarian failure. Optimizing donor recruitment is essential to obtain the best results with this technique. Understanding how donor parameters influence outcome for the recipients is fundamental. The aim of this study was to determine whet...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Delesalle AS,Robin G,Thomas-Desrousseaux P,Dewailly D,Catteau-Jonard S

更新日期：2016-01-19 00:00:00

abstract：:LINE1 retrotransposons are mobile DNA elements that copy and paste themselves into new sites in the genome. To ensure their evolutionary success, heritable new LINE-1 insertions accumulate in cells that can transmit genetic information to the next generation (i.e., germ cells and embryonic stem cells). It is our hypot...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Lou C,Goodier JL,Qiang R

更新日期：2020-01-21 00:00:00

abstract：BACKGROUND:Endometriosis has been shown to be associated with second- to third-trimester pregnancy complications such as preterm birth and placenta previa, but the evidence is inconsistent. We hypothesized that endometriosis severity might affect these inconsistent results. Therefore we aimed to conduct a retrospective...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Fujii T,Wada-Hiraike O,Nagamatsu T,Harada M,Hirata T,Koga K,Fujii T,Osuga Y

更新日期：2016-11-03 00:00:00

abstract：:Transient receptor potential cation channel, subfamily V, member 6 (TRPV6) is an epithelial Ca2+ channel protein expressed in calcium absorbing organs. In the present study, we investigated the expression and regulation of uterine and placental TRPV6 during gestation in rodents. Uterine TRPV6 peaked at pregnancy day (...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Lee BM,Lee GS,Jung EM,Choi KC,Jeung EB

更新日期：2009-05-21 00:00:00

abstract：:Preimplantation embryo development involves four stages: fertilization, cell cleavage, morula and blastocyst formation. During these stages, maternal and zygotic epigenetic factors play crucial roles. The gene expression profile is changed dramatically, chromatin is modified and core histone elements undergo significa...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Shi L,Wu J

更新日期：2009-06-05 00:00:00

abstract：:The prolonged lockdown of health services providing high-complexity fertility treatments -as currently recommended by many reproductive medicine entities- is detrimental for society as a whole, and infertility patients in particular. Globally, approximately 0.3% of all infants born every year are conceived using assis...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Alviggi C,Esteves SC,Orvieto R,Conforti A,La Marca A,Fischer R,Andersen CY,Bühler K,Sunkara SK,Polyzos NP,Strina I,Carbone L,Bento FC,Galliano D,Yarali H,Vuong LN,Grynberg M,Drakopoulos P,Xavier P,Llacer J,Neuspil

更新日期：2020-05-13 00:00:00

abstract：:During the follicular phase of the primate menstrual cycle, a single follicle usually matures to the preovulatory stage and releases its oocyte for fertilization and the potential establishment of pregnancy. In assisted reproductive technology procedures, it is desirable to override the natural process of follicle sel...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zeleznik AJ

更新日期：2004-06-16 00:00:00

abstract：BACKGROUND:Despite the clinical outcomes of ovarian stimulation with either GnRH-agonist or GnRH-antagonist analogues for in vitro fertilization (IVF) being well analysed, the effect of analogues on oocyte/embryo quality and embryo development is still not known in detail. The aim of this case-control study was to comp...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Murber A,Fancsovits P,Ledó N,Gilán ZT,Rigó J Jr,Urbancsek J

更新日期：2009-09-25 00:00:00

abstract：BACKGROUND:The Rapid-i is a new FDA cleared closed carrier for embryo vitrification. The cooling rate of - 1220°C/min is far lower than that reported with open vitrification systems such as the cryoloop (-15,000°C/min). Little published data is currently available on this device. This study presents our initial clinica...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Desai NN,Goldberg JM,Austin C,Falcone T

更新日期：2013-05-15 00:00:00

abstract：BACKGROUND:Bovine luteal parenchymal cells express class II major histocompatibility complex (MHC) molecules and stimulate class II MHC-dependent activation of T cells in vitro. The ability of a class II MHC-expressing cell type to elicit a response from T cells in vivo is also dependent on expression of costimulatory ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Cannon MJ,Davis JS,Pate JL

更新日期：2007-01-31 00:00:00

abstract：BACKGROUND:In several species, considerably higher levels of estradiol-17 (E2) are synthesized in the CL. E2 has been suggested to participate in the regulation of luteal steroidogenesis and luteal cell morphology. In pregnant rats, several experiments have been carried out to examine the effects of inhibition of lutea...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Tripathy S,Asaithambi K,Jayaram P,Medhamurthy R

更新日期：2016-04-12 00:00:00

abstract：BACKGROUND:In natural cycles, women conceive when intercourse takes place during a six-day period ending on the day of ovulation. The current practice in intrauterine insemination (IUI) cycles is to perform the IUI 24-36 hours after the hCG administration, when the ovulation is already imminent. In this study hCG was a...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Järvelä IY,Tapanainen JS,Martikainen H

更新日期：2010-02-23 00:00:00

abstract：BACKGROUND:Relaxin levels in seminal plasma have been associated with positive effects on sperm motility and quality, and thus having potential roles in male fertility. However, the origin of seminal relaxin, within the male reproductive tract, and the moment of its release in the vicinity of spermatozoa remain unclear...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Feugang JM,Greene JM,Sanchez-Rodríguez HL,Stokes JV,Crenshaw MA,Willard ST,Ryan PL

更新日期：2015-05-20 00:00:00