Epidemiology of polycystic ovary syndrome: a cross sectional study of university students at An-Najah national university-Palestine.

abstract：BACKGROUND:Experiments were designed to identify the developmental expression and function of the Dickkopf-Like1 (DKKL1/Dkkl1) gene in humans and mice. METHODS:Mouse testes cDNA samples were collected at multiple postnatal times (days 4, 9, 18, 35, and 54, as well as at 6 months) and hybridized to Affymetrix mouse who...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Yan Q,Wu X,Chen C,Diao R,Lai Y,Huang J,Chen J,Yu Z,Gui Y,Tang A,Cai Z

更新日期：2012-07-21 00:00:00

abstract：BACKGROUND:Women with Polycystic Ovary Syndrome (PCOS) present a heterogeneous reproductive and metabolic profile with an increased lifetime risk of Type 2 Diabetes (T2D). Early biomarkers of these metabolic disturbances in PCOS women have not been identified. The abundance of circulating insulin gene promotor cell-fre...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Udesen PB,Sørensen AE,Joglekar MV,Hardikar AA,Wissing MLM,Englund AM,Dalgaard LT

更新日期：2019-04-05 00:00:00

abstract：BACKGROUND:Serum leptin levels are augmented in obese infertile men and in men with azoospermia. They also correlate inversely with sperm concentration, motility and normal forms. The mechanisms underlying the adverse effects of excess leptin on male reproductive function remain unclear. The present study aimed to eval...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Wang X,Zhang X,Hu L,Li H

更新日期：2018-05-31 00:00:00

abstract：BACKGROUND:Endocrine mechanisms governing canine reproductive function remain still obscure. Progesterone (P4) of luteal origin is required for maintenance of pregnancy. Corpora lutea (CL) are gonadotrop-independent during the first third of dioestrus; afterwards prolactin (PRL) is the primary luteotropic factor. Inter...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Kowalewski MP,Michel E,Gram A,Boos A,Guscetti F,Hoffmann B,Aslan S,Reichler I

更新日期：2011-08-03 00:00:00

abstract：OBJECTIVES:It is essential to understand the molecular basis of ovarian cancer etiology and tumor development to provide more effective preventive and therapeutic approaches to reduce mortality. Particularly, the molecular targets and pathways involved in early malignant transformation are still not clear. Pro-inflamma...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zhang L,Wang D,Jiang W,Edwards D,Qiu W,Barroilhet LM,Rho JH,Jin L,Seethappan V,Vitonis A,Wang J,Mok SC,Crum C,Cramer DW,Ye B

更新日期：2010-06-24 00:00:00

abstract：BACKGROUND:The study was designed to test the hypothesis that granulosa cell (GC) gene expression response differs between recombinant FSH and human menopausal gonadotropin (hMG) stimulation regimens. METHODS:Females < 35 years-old undergoing IVF for tubal or male factor infertility were prospectively randomized to on...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Brannian J,Eyster K,Mueller BA,Bietz MG,Hansen K

更新日期：2010-03-12 00:00:00

abstract：BACKGROUND:17alpha-Estradiol has been considered as the hormonally inactive isomer of 17beta-estradiol. Recently, nongenomic (smooth muscle relaxation) and genomic (light estrogenic activity) effects of 17alpha-estradiol have been reported, but no reports have yet determined its possible antiestrogenic activity. Theref...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Perusquía M,Navarrete E

更新日期：2005-07-21 00:00:00

abstract：BACKGROUND:We examined the presence and function of tachykinins and the tachykinin-degrading enzymes neprilysin (NEP) and neprilysin-2 (NEP2) in human spermatozoa. METHODS:Freshly ejaculated semen was collected from forty-eight normozoospermic human donors. We analyzed the expression of substance P, neurokinin A, neur...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Pinto FM,Ravina CG,Subiran N,Cejudo-Román A,Fernández-Sánchez M,Irazusta J,Garrido N,Candenas L

更新日期：2010-08-26 00:00:00

abstract：BACKGROUND:Peripheral and uterine natural killer cells (pNK and uNK cells) are key players in the establishment and maintenance of pregnancy and are disturbed in patients with recurrent miscarriage (RM). Different immunologic risk factors have been proposed between patients with primary RM (pRM, no previous live birth)...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Toth B,Vomstein K,Togawa R,Böttcher B,Hudalla H,Strowitzki T,Daniel V,Kuon RJ

更新日期：2019-08-31 00:00:00

abstract：:Decidualization is an intricate biological process where extensive morphological, functional, and genetic changes take place in endometrial stromal cells to support the development of an implanting blastocyst. Deficiencies in decidualization are associated with pregnancy complications and reproductive diseases. Decidu...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Ni N,Li Q

更新日期：2017-10-13 00:00:00

abstract：BACKGROUND:Gonadal differentiation in the mammalian fetus involves a complex dose-dependent genetic network. Initiation and progression of fetal ovarian and testicular pathways are accompanied by dynamic expression patterns of thousands of genes. We postulate these expression patterns are regulated by small non-coding ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Torley KJ,da Silveira JC,Smith P,Anthony RV,Veeramachaneni DN,Winger QA,Bouma GJ

更新日期：2011-01-11 00:00:00

abstract：:Gonadotropin-primed immature rats (GPIR) constitute a widely used model for the study of ovulation. Although the equivalence between the ovulatory process in immature and adult rats is generally assumed, the morphological and functional characteristics of ovulation in immature rats have been scarcely considered. We de...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gaytan M,Bellido C,Morales C,Gonzalez-Padilla M,Sanchez-Criado JE,Gaytan F

更新日期：2004-09-03 00:00:00

abstract：BACKGROUND:Di(2-ethylhexyl) phthalate (DEHP) exposure reduces embryo implantations, increases embryonic loss, and decreases fetal body weights. However, whether it is associated with the alteration of luteal function remains unknown. Thus, our aim in this study was to explore the effect and mechanism of DEHP on luteal ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Guo M,Lai L,Zong T,Lin Y,Yang B,Zhang L,Li M,Kuang H

更新日期：2015-03-03 00:00:00

abstract：BACKGROUND:Patients hoping to preserve their fertility receive conservative treatment with high-dose medroxyprogesterone acetate (MPA) for well-differentiated endometrioid adenocarcinoma (EC) or atypical endometrial hyperplasia (AEH) . Such treatment generally involves frequent intrauterine operations, including dilati...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Inoue O,Hamatani T,Susumu N,Yamagami W,Ogawa S,Takemoto T,Hirasawa A,Banno K,Kuji N,Tanaka M,Aoki D

更新日期：2016-01-15 00:00:00

abstract：BACKGROUND:In several species, considerably higher levels of estradiol-17 (E2) are synthesized in the CL. E2 has been suggested to participate in the regulation of luteal steroidogenesis and luteal cell morphology. In pregnant rats, several experiments have been carried out to examine the effects of inhibition of lutea...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Tripathy S,Asaithambi K,Jayaram P,Medhamurthy R

更新日期：2016-04-12 00:00:00

abstract：:Sexual health is strictly related with general health in both genders. In presence of a sexual dysfunction, the expert in sexual medicine aims to discover the specific weight of the physical and psychological factors can cause or con-cause the sexual problem. At the same time, a sexual dysfunction can represent a mark...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Mollaioli D,Ciocca G,Limoncin E,Di Sante S,Gravina GL,Carosa E,Lenzi A,Jannini EAF

更新日期：2020-02-17 00:00:00

abstract：BACKGROUND:The placenta is an essential organ that provides nutrients and oxygen to the developing fetus and removes toxic waste products from the fetal circulation. Maintaining placental blood osmotic pressure and blood flow is crucial for viable offspring. The renin-angiotensin system (RAS) in the placenta is a key p...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Vaswani K,Chan HW,Verma P,Dekker Nitert M,Peiris HN,Wood-Bradley RJ,Armitage JA,Rice GE,Mitchell MD

更新日期：2015-08-12 00:00:00

abstract：BACKGROUND:The aim of this study was to compare pregnancy rates in patients undergoing IVF/ICSI with embryo transfer after 4 and 5 days of culture in a closed incubation system with integrated time-lapse imaging. METHODS:Out of n = 2207 in vitro fertilization (IVF)/ intracytoplasmic sperm injection (ICSI) cycles perfo...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Holschbach V,Weigert J,Dietrich JE,Roesner S,Montag M,Strowitzki T,Toth B

更新日期：2017-05-08 00:00:00

abstract：BACKGROUND:High altitude is associated with both low pulse oxygen saturation at birth and more pre-term deliveries. The present study was performed to determine pulse oxygen saturation in newborns at term in Cerro de Pasco (4340 m) and Lima (150 m) to test the hypothesis that low pulse oxygen saturation at birth at hig...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gonzales GF,Salirrosas A

更新日期：2005-09-12 00:00:00

abstract：:Establishment and maintenance of pregnancy in the pig involves intricate communication between the developing conceptuses and the maternal endometrium. This process occurs during trophoblast elongation which is spaciotemporally associated with conceptus synthesis and release of IL1B concomitant with pregnancy-specific...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Ross JW,Ashworth MD,Mathew D,Reagan P,Ritchey JW,Hayashi K,Spencer TE,Lucy M,Geisert RD

更新日期：2010-04-28 00:00:00

abstract：BACKGROUND:Spontaneous abortion is one of the most common complications in early pregnancy. A preventive test to identify women who will experience a miscarriage, even before first symptoms occur, is not established. Activation of maternal immunological tolerance seems to be essential for early fetal development and va...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Freis A,Schlegel J,Daniel V,Jauckus J,Strowitzki T,Germeyer A

更新日期：2018-09-28 00:00:00

abstract：:The response of Meishan conceptuses to an exogenous precursor for oestradiol-17beta biosynthesis was investigated in vitro, to determine whether gestational age or morphological stage of development elicit changes in hormone metabolism. Conceptuses were recovered on days 11, 12, 13 or 15 after the onset of oestrus and...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Pickard AR,Miller SJ,Ashworth CJ

更新日期：2003-02-11 00:00:00

abstract：BACKGROUND:Adequate maternal nutrition during gestation is requisite for fetal nutrition and development. While a large group of epidemiological studies indicate poor fetal nutrition increases heart disease risk and mortality in later life, little work has focused on the effects of impaired maternal nutrition on fetal ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gilbert JS,Lang AL,Nijland MJ

更新日期：2005-07-14 00:00:00

abstract：BACKGROUND:The syncytialization of cytotrophoblast cells to syncytiotrophoblast is central to human placental transport and hormone production. Many techniques for in vitro study of this process have been proposed and new investigators to the field may find the literature in the field daunting. Here, we present a strai...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Li L,Schust DJ

更新日期：2015-07-09 00:00:00

abstract：BACKGROUND:Dehydroepinadrosterone (DHEA) supplementation improves pregnancy chances in women with diminished ovarian reserve (DOR), by possibly reducing aneuploidy. Since a large majority of spontaneous miscarriages are associated with aneuploidy, one can speculate that DHEA supplementation may also reduce miscarriage ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gleicher N,Ryan E,Weghofer A,Blanco-Mejia S,Barad DH

更新日期：2009-10-07 00:00:00

abstract：BACKGROUND:There is limited literature investigating the effects of body mass index (BMI) and androgen level on in vitro fertilization (IVF) outcomes with a gonadotropin-releasing hormone (GnRH)-antagonist protocol in polycystic ovary syndrome (PCOS). Androgen-related variation in the effect of body mass index (BMI) on...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Yang W,Yang R,Lin M,Yang Y,Song X,Zhang J,Yang S,Song Y,Li J,Pang T,Deng F,Zhang H,Wang Y,Li R,Jiao J

更新日期：2018-11-19 00:00:00

abstract：BACKGROUND:Claudin-4 (CLDN4) is one of several proteins that act as molecular mediators of embryo implantation. Recently, we examined immunolabeling of leukemia inhibitory factor (LIF) in the endometrial tissue of 52 IVF patients, and found that LIF staining intensity was strongly correlated with successful pregnancy i...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Serafini PC,Silva ID,Smith GD,Motta EL,Rocha AM,Baracat EC

更新日期：2009-04-19 00:00:00

abstract：BACKGROUND:The injection of estradiol valerate in female rats induces polycystic ovary syndrome, which is characterized by polycystic ovaries, anovulation, and hyperandrogenism. These characteristics have been associated with an increase in the ovarian concentration of norepinephrine, which occurs before establishing t...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Espinoza JA,Alvarado W,Venegas B,Domínguez R,Morales-Ledesma L

更新日期：2018-09-07 00:00:00

abstract：BACKGROUND:Relaxin is detected in seminal plasma of many species and its association with sperm motility may be beneficial in some aspects of assisted reproduction. Here, we immunolocalized relaxin receptors and investigated the effects of exogenous relaxin on motility characteristics, viability, and cAMP content of bo...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Feugang JM,Rodríguez-Muñoz JC,Dillard DS,Crenshaw MA,Willard ST,Ryan PL

更新日期：2015-03-31 00:00:00

abstract：BACKGROUND:Prostaglandins are important for female reproduction. Prostaglandin-E2 acts via four different receptor subtypes, EP1, EP2, EP3 and EP4 whereas prostaglandin-F2alpha acts through FP. The functions of prostaglandins depend on the expression of their receptors in different uterine cell types. Our aim was to in...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Blesson CS,Büttner E,Masironi B,Sahlin L

更新日期：2012-01-18 00:00:00