Effects of N-acetyl-cysteine supplementation on sperm quality, chromatin integrity and level of oxidative stress in infertile men.

abstract：BACKGROUND:The G protein-coupled estrogen receptor (GPER) is thought to be involved in non-genomic estrogen responses as well as processes such as cell proliferation and migration. In this study, we analyzed GPER expression patterns from endometriosis samples and normal endometrial tissue samples and compared these exp...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Samartzis N,Samartzis EP,Noske A,Fedier A,Dedes KJ,Caduff R,Fink D,Imesch P

更新日期：2012-04-20 00:00:00

abstract：BACKGROUND:To evaluate the association between leukocytes (polymorphonuclear granulocytes -PMNL) and semen parameters at different leukocyte concentrations. METHODS:This was a retrospective clinical study at a university hospital andrology clinic. Semen samples from infertile men were analyzed for sperm morphology and...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Lackner JE,Agarwal A,Mahfouz R,du Plessis SS,Schatzl G

更新日期：2010-02-05 00:00:00

abstract：BACKGROUND:Relaxin is detected in seminal plasma of many species and its association with sperm motility may be beneficial in some aspects of assisted reproduction. Here, we immunolocalized relaxin receptors and investigated the effects of exogenous relaxin on motility characteristics, viability, and cAMP content of bo...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Feugang JM,Rodríguez-Muñoz JC,Dillard DS,Crenshaw MA,Willard ST,Ryan PL

更新日期：2015-03-31 00:00:00

abstract：BACKGROUND:The cell membrane water channel protein, aquaporins (AQPs), regulate cellular water transport and cell volume and play a key role in water homeostasis. Recently, AQPs are considered as important players in the field of reproduction. In previous studies, we have established the presence of AQP1 and 5 in porci...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Skowronska A,Młotkowska P,Wojciechowicz B,Okrasa S,Nielsen S,Skowronski MT

更新日期：2015-02-18 00:00:00

abstract：BACKGROUND:hCG is a wonder. Firstly, because hCG is such an extreme molecule. hCG is the most acidic glycoprotein containing the highest proportion of sugars. Secondly, hCG exists in 5 common forms. Finally, it has so many functions ranging from control of human pregnancy to human cancer. This review examines these mol...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Cole LA

更新日期：2012-03-28 00:00:00

abstract：:Macaques are menstruating nonhuman primates that provide important animal models for studies of hormonal regulation in the uterus. In women and macaques the decline of progesterone (P) at the end of the cycle triggers endometrial expression of a variety of matrix metalloproteinase (MMP) enzymes that participate in tis...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Slayden OD,Brenner RM

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:With infertility populations rapidly aging, treatments improving pregnancy chances assume increasing clinical importance. Dehydroepiandrosterone (DHEA) has been reported to improve pregnancy rates and lower miscarriage rates in women with diminished ovarian function. This study was planned to evaluate whethe...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Tartagni M,Cicinelli MV,Baldini D,Tartagni MV,Alrasheed H,DeSalvia MA,Loverro G,Montagnani M

更新日期：2015-03-09 00:00:00

abstract：BACKGROUND:Limitations in our current knowledge of normative physiologic changes in thyroid function during the periconception window narrow our ability to establish an optimal approach to screening and diagnosis of thyroid disease in pregnant women. The objective of this study was to characterize changes in thyroid fu...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Balthazar U,Steiner AZ

更新日期：2012-03-21 00:00:00

abstract：BACKGROUND:Serum leptin levels are augmented in obese infertile men and in men with azoospermia. They also correlate inversely with sperm concentration, motility and normal forms. The mechanisms underlying the adverse effects of excess leptin on male reproductive function remain unclear. The present study aimed to eval...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Wang X,Zhang X,Hu L,Li H

更新日期：2018-05-31 00:00:00

abstract：BACKGROUND:To assess the amount of variability in ovarian follicular growth rate and maximum follicular diameter related to different centers, women and cycles of the same women in a multicenter observational study of follicular growth. METHODS:Secondary analysis of a prospective cohort study from eight centers in Eur...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Mikolajczyk RT,Stanford JB,Ecochard R

更新日期：2008-12-10 00:00:00

abstract：BACKGROUND:Polycystic Ovary Syndrome (PCOS) is the most common gynecological endocrinopathy in women of reproductive age. Despite its heavy burden on female reproduction and general health, there is no study regarding PCOS prevalence in Palestine. This study aims to establish prevalence of PCOS among female university ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Musmar S,Afaneh A,Mo'alla H

更新日期：2013-05-20 00:00:00

abstract：OBJECTIVE:To assess the effectiveness and safety of omega-3 fatty acid for patients with PCOS. METHODS:In this meta-analysis, data from randomized controlled trials were obtained to assess the effects of omega-3 fatty acid versus placebo or western medicine in women with PCOS. The study's registration number is CRD420...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Yang K,Zeng L,Bao T,Ge J

更新日期：2018-03-27 00:00:00

abstract：BACKGROUND:Macrophage migration inhibitory factor (MIF) has special pro-inflammatory roles, affecting the functions of macrophages and lymphocytes and counter-regulating the effects of glucocorticoids on the immune response. The conspicuous expression of MIF during human implantation and early embryonic development als...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Faria MR,Hoshida MS,Ferro EA,Ietta F,Paulesu L,Bevilacqua E

更新日期：2010-08-04 00:00:00

abstract：BACKGROUND:Turkey reproduction is by artificial insemination using pooled semen so there is interest in storing semen. Fertilizing capacity declines after six hours storage, possibly due to poor sperm mobility. Prostaglandins (PG) affect mammalian sperm motility, but avian sperm has not been widely studied. For this st...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Kennedy JH,Korn N,Thurston RJ

更新日期：2003-10-09 00:00:00

abstract：BACKGROUND:Despite being born with a significant number of primordial cells which representing the ancestor cells of the germ-line, women experience a depletion of ovarian reserve and sub-fertility mid-way into their healthy lives. The poor ovarian response is a substantial limiting factor amplified with higher materna...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Khan HL,Bhatti S,Suhail S,Gul R,Awais A,Hamayun H,Enver F,Abbas S,Hassan Z,Nisar R,Sardar S,Asif W

更新日期：2019-02-11 00:00:00

abstract：BACKGROUND:Mammalian oocyte meiotic maturation involves a number of important processes, including spindle assembly and migration, cortical reorganization and polar body extrusion. Numerous proteins contribute to these processes, but it is unknown whether MKlp2 (mitotic kinesin-like protein 2; also called KIF20A), a mi...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Liu J,Wang QC,Cui XS,Wang ZB,Kim NH,Sun SC

更新日期：2013-12-21 00:00:00

abstract：BACKGROUND:Endometriosis is a known cause of infertility. Differences in immune tolerance caused by regulatory T cells (Tregs) and transforming growth factor-β (TGF-β) are thought to be involved in the pathology of endometriosis. Evidence has indicated that Tregs can be separated into three functionally and phenotypica...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Hanada T,Tsuji S,Nakayama M,Wakinoue S,Kasahara K,Kimura F,Mori T,Ogasawara K,Murakami T

更新日期：2018-02-01 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) is a common endocrine disorder, affecting 9-18% of women in reproductive age that causes hyperandrogenism and infertility due to dysfunctional follicular maturation and anovulation. The etiology of PCOS is still poorly known, and information from experimental animal models may help imp...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Paixão L,Ramos RB,Lavarda A,Morsh DM,Spritzer PM

更新日期：2017-02-10 00:00:00

abstract：BACKGROUND:Endometriosis is a well-known cause of infertility, and the anti-Mullerian hormone (AMH) is an accepted biomarker of ovarian reserve and response to artificial reproductive technology procedures. The present study was a prospective analysis of age-dependent AMH serum concentration in women with bilateral and...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Nieweglowska D,Hajdyla-Banas I,Pitynski K,Banas T,Grabowska O,Juszczyk G,Ludwin A,Jach R

更新日期：2015-11-24 00:00:00

abstract：BACKGROUND:Nomegestrol acetate (NOMAC), a synthetic progestogen derived from 19-nor-progesterone, recently completed clinical trials for use with 17beta-estradiol in a new monophasic combined oral contraceptive. In this review, published as well as previously unpublished preclinical studies that detail the effects of N...

journal_title：Reproductive biology and endocrinology : RB&E

authors： van Diepen HA

更新日期：2012-10-08 00:00:00

abstract：BACKGROUND:Di(2-ethylhexyl) phthalate (DEHP) exposure reduces embryo implantations, increases embryonic loss, and decreases fetal body weights. However, whether it is associated with the alteration of luteal function remains unknown. Thus, our aim in this study was to explore the effect and mechanism of DEHP on luteal ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Guo M,Lai L,Zong T,Lin Y,Yang B,Zhang L,Li M,Kuang H

更新日期：2015-03-03 00:00:00

abstract：:The prolonged lockdown of health services providing high-complexity fertility treatments -as currently recommended by many reproductive medicine entities- is detrimental for society as a whole, and infertility patients in particular. Globally, approximately 0.3% of all infants born every year are conceived using assis...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Alviggi C,Esteves SC,Orvieto R,Conforti A,La Marca A,Fischer R,Andersen CY,Bühler K,Sunkara SK,Polyzos NP,Strina I,Carbone L,Bento FC,Galliano D,Yarali H,Vuong LN,Grynberg M,Drakopoulos P,Xavier P,Llacer J,Neuspil

更新日期：2020-05-13 00:00:00

abstract：BACKGROUND:Overweight and obese women have been shown to have an increased risk of recurrent miscarriage as well as other adverse reproductive outcomes, but it is yet unclear whether this is due to an effect on the endometrium, embryo or both. The current study employs proteomic analysis to examine for a potential endo...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Metwally M,Preece R,Thomas J,Ledger W,Li TC

更新日期：2014-08-05 00:00:00

abstract：BACKGROUND:Adequate maternal nutrition during gestation is requisite for fetal nutrition and development. While a large group of epidemiological studies indicate poor fetal nutrition increases heart disease risk and mortality in later life, little work has focused on the effects of impaired maternal nutrition on fetal ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gilbert JS,Lang AL,Nijland MJ

更新日期：2005-07-14 00:00:00

abstract：BACKGROUND:Age at menarche is the reflection of cumulative pre-adolescent exposure of girls to either adverse environment such as food insecurity or affluent living conditions. Food insecurity could result in inadequate nutrient intake and stress, both of which are hypothesized to have opposing effects on the timing of...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Belachew T,Hadley C,Lindstrom D,Getachew Y,Duchateau L,Kolsteren P

更新日期：2011-09-13 00:00:00

abstract：BACKGROUND:Pregnant women have high serum concentrations of sex steroid hormones, which are major regulators of paracrine and autocrine responses for many maternal and placental functions. The main purpose of this study was to compare patients with preeclampsia and patients with uncomplicated pregnancies in terms of se...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Lan KC,Lai YJ,Cheng HH,Tsai NC,Su YT,Tsai CC,Hsu TY

更新日期：2020-02-18 00:00:00

abstract：BACKGROUND:Brain-derived ectonucleoside triphosphate diphosphohydrolases (NTPDases) have been known as plasma membrane-incorporated enzymes with their ATP-hydrolyzing domain outside of the cell. As such, these enzymes are thought to regulate purinergic intercellular signaling by hydrolyzing ATP to ADP-AMP, thus regulat...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zsarnovszky A,Bartha T,Frenyo LV,Diano S

更新日期：2009-06-16 00:00:00

abstract：BACKGROUND:To study the expression of Plexin-B1, Glycodelin, and MMP7 during the menstrual cycle in the endometrium and in the fallopian tube. METHODS:The research included women undergoing hysterectomy, tubal sterilization or salpingo-oophoerectomy. Total RNA from endometrial and fallopian tube tissues was extracted ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Amir M,Romano S,Goldman S,Shalev E

更新日期：2009-12-29 00:00:00

abstract：BACKGROUND:The physiological state of the dominant follicle is important as it may be linked to the competence of the oocyte within. The objective of this study was to analyze, by transcriptomic analysis, the changes occurring in granulosa cells from dominant follicles at different phases of follicular growth. METHODS...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Girard A,Dufort I,Douville G,Sirard MA

更新日期：2015-03-08 00:00:00

abstract：BACKGROUND:Dehydroepinadrosterone (DHEA) supplementation improves pregnancy chances in women with diminished ovarian reserve (DOR), by possibly reducing aneuploidy. Since a large majority of spontaneous miscarriages are associated with aneuploidy, one can speculate that DHEA supplementation may also reduce miscarriage ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gleicher N,Ryan E,Weghofer A,Blanco-Mejia S,Barad DH

更新日期：2009-10-07 00:00:00