hCG, the wonder of today's science.

abstract：BACKGROUND:A decrease in HOXA11 expression in eutopic mid-secretory endometrium has been found in women with endometriosis-associated infertility. METHODS:Using Real-time quantitative PCR (RQ-PCR) and western blotting analysis we studied the HOXA11 transcript and protein levels in mid-luteal eutopic endometrium from e...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Szczepańska M,Wirstlein P,Skrzypczak J,Jagodziński PP

更新日期：2012-01-10 00:00:00

abstract：BACKGROUND:Flow cytometric sorting can be used to separate sperm based on sex chromosome content. Differential fluorescence emitted by stained X- vs. Y-chromosome-bearing sperm enables sorting and collection of samples enriched in either X- or Y-bearing sperm for use to influence the likelihood that the offspring will ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Karabinus DS,Marazzo DP,Stern HJ,Potter DA,Opanga CI,Cole ML,Johnson LA,Schulman JD

更新日期：2014-11-24 00:00:00

abstract：BACKGROUND:Adrenomedullin (ADM), a novel vasorelaxant peptide, was found in human/rat ovaries. The present study investigated the interaction of ADM and endothelin-1 (ET-1) in follicles and newly formed corpora lutea (CL) and the actions of ADM on progesterone production in CL during pregnancy. METHODS:The peptide and...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Li L,O WS,Tang F

更新日期：2011-08-09 00:00:00

abstract：BACKGROUND:Infertile men have higher levels of semen reactive oxygen species (ROS) than fertile men. High levels of semen ROS can cause sperm dysfunction, sperm DNA damage and reduced male reproductive potential. This study investigated the effects of supplementation with N-acetyl-cysteine (NAC) on the sperm quality, c...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Jannatifar R,Parivar K,Roodbari NH,Nasr-Esfahani MH

更新日期：2019-02-16 00:00:00

abstract：BACKGROUND:Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder associated with ovulatory dysfunction, abdominal obesity, hyperandrogenism, hypertension, and insulin resistance. METHODS:Our objectives in this study were (1) to estimate sympathetic-adrenal medullary (SAM) activity by measuring...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Stener-Victorin E,Ploj K,Larsson BM,Holmäng A

更新日期：2005-09-07 00:00:00

abstract：BACKGROUND:Despite being born with a significant number of primordial cells which representing the ancestor cells of the germ-line, women experience a depletion of ovarian reserve and sub-fertility mid-way into their healthy lives. The poor ovarian response is a substantial limiting factor amplified with higher materna...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Khan HL,Bhatti S,Suhail S,Gul R,Awais A,Hamayun H,Enver F,Abbas S,Hassan Z,Nisar R,Sardar S,Asif W

更新日期：2019-02-11 00:00:00

abstract：BACKGROUND:The fibrinolytic system and its inhibitors play a number of roles, apart from their function in blood haemostasis and thrombosis, namely in ovarian folliculogenesis and in ovulation. Plasminogen is converted to active plasmin at the time of follicular rupture through a decrease in plasminogen activator inhib...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Burchall GF,Pouniotis DS,Teede HJ,Ranasinha S,Walters KA,Piva TJ

更新日期：2019-03-16 00:00:00

abstract：BACKGROUND:Estradiol (E2) and progesterone (P) are well known regulators of progesterone receptor (PR) expression in the rat uterus. However, it is not known which receptor subtypes are involved. Little knowledge exist about possible differences in PR regulation through ERalpha or ERbeta, and whether the PR subtypes ar...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Sahlin L,Masironi B,Akerberg S,Eriksson H

更新日期：2006-09-11 00:00:00

abstract：:Human embryonic stem cells (hESC) have emerged as attractive candidates for cell-based therapies that are capable of restoring lost cell and tissue function. These unique cells are able to self-renew indefinitely and have the capacity to differentiate in to all three germ layers (ectoderm, endoderm and mesoderm). Harn...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Desai N,Rambhia P,Gishto A

更新日期：2015-02-22 00:00:00

abstract：BACKGROUND:The G protein-coupled estrogen receptor (GPER) is thought to be involved in non-genomic estrogen responses as well as processes such as cell proliferation and migration. In this study, we analyzed GPER expression patterns from endometriosis samples and normal endometrial tissue samples and compared these exp...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Samartzis N,Samartzis EP,Noske A,Fedier A,Dedes KJ,Caduff R,Fink D,Imesch P

更新日期：2012-04-20 00:00:00

abstract：BACKGROUND:Adequate maternal nutrition during gestation is requisite for fetal nutrition and development. While a large group of epidemiological studies indicate poor fetal nutrition increases heart disease risk and mortality in later life, little work has focused on the effects of impaired maternal nutrition on fetal ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gilbert JS,Lang AL,Nijland MJ

更新日期：2005-07-14 00:00:00

abstract：:The corpus luteum is an endocrine gland whose limited lifespan is hormonally programmed. This debate article summarizes findings of our research group that challenge the principle that the end of function of the corpus luteum or luteal regression, once triggered, cannot be reversed. Overturning luteal regression by ph...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Telleria CM

更新日期：2006-10-30 00:00:00

abstract：:Endometrial carcinoma is the most common neoplasm of the female genital tract, accounting for nearly one half of all gynecologic cancers in the Western world. Although intensive research on pathological phenomena of endometrial cancer is currently going on, but exact cause and biological aspects of this disease are no...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Park DW,Choi KC,MacCalman CD,Leung PC

更新日期：2009-08-05 00:00:00

abstract：BACKGROUND:In early pregnancy, increased plasma levels of the endocannabinoid anandamide (AEA) are associated with miscarriage through mechanisms that might affect the developing placenta or maternal decidua. METHODS:In this study, we compare AEA levels in failed and viable pregnancies with the levels of the trophobla...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Taylor AH,Finney M,Lam PM,Konje JC

更新日期：2011-11-29 00:00:00

abstract：BACKGROUND:Intracytoplasmic morphologically selected sperm injection (IMSI) is still proposed and employed in the clinical practice to improve the reproductive outcome in infertile couples scheduled for conventional intracytoplasmic sperm injection (cICSI). The aim of the current randomized controlled trial (RCT) was t...

journal_title：Reproductive biology and endocrinology : RB&E

authors： La Sala GB,Nicoli A,Fornaciari E,Falbo A,Rondini I,Morini D,Valli B,Villani MT,Palomba S

更新日期：2015-08-27 00:00:00

abstract：BACKGROUND:The injection of estradiol valerate in female rats induces polycystic ovary syndrome, which is characterized by polycystic ovaries, anovulation, and hyperandrogenism. These characteristics have been associated with an increase in the ovarian concentration of norepinephrine, which occurs before establishing t...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Espinoza JA,Alvarado W,Venegas B,Domínguez R,Morales-Ledesma L

更新日期：2018-09-07 00:00:00

abstract：BACKGROUND:ATF6α, one of the sensor proteins in the stress signaling pathway of the endoplasmic reticulum, is located in the membrane of the endoplasmic reticulum. To date, the physiological function of ATF6α in the process of embryo implantation has not been reported. METHODS:In this study, the expression pattern of ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Xiong Y,Li W,Lin P,Wang L,Wang N,Chen F,Li X,Wang A,Jin Y

更新日期：2016-10-07 00:00:00

abstract：BACKGROUND:Seminal plasma serves as a natural reservoir of antioxidants. It helps to remove excessive formation of reactive oxygen species (ROS) and consequently, reduce oxidative stress. Proteomic profiling of seminal plasma proteins is important to understand the molecular mechanisms underlying oxidative stress and s...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Sharma R,Agarwal A,Mohanty G,Du Plessis SS,Gopalan B,Willard B,Yadav SP,Sabanegh E

更新日期：2013-09-03 00:00:00

abstract：BACKGROUND:In natural cycles, women conceive when intercourse takes place during a six-day period ending on the day of ovulation. The current practice in intrauterine insemination (IUI) cycles is to perform the IUI 24-36 hours after the hCG administration, when the ovulation is already imminent. In this study hCG was a...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Järvelä IY,Tapanainen JS,Martikainen H

更新日期：2010-02-23 00:00:00

abstract：:We have investigated the effects of indomethacin (IM), a non-steroidal anti-inflammatory drug, and the role of prostaglandins on the accumulation of leukocytes in the rat ovary during the periovulatory period. Adult cycling rats were injected sc with 1 mg of IM in olive oil or vehicle on the morning of proestrus. Some...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gaytán F,Morales C,Bellido C,Tarradas E,Sánchez-Criado JE

更新日期：2003-02-14 00:00:00

abstract：BACKGROUND:Stereology is an established method to extrapolate three-dimensional quantities from two-dimensional images. It was applied to placentation in the mouse, but not yet for other rodents. Herein, we provide the first study on quantitative placental development in a sigmodontine rodent species with relatively si...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Favaron PO,Mess AM,de Oliveira MF,Gabory A,Miglino MA,Chavatte-Palmer P,Tarrade A

更新日期：2013-02-21 00:00:00

abstract：BACKGROUND:In animals, low levels of vitamin D are associated with estrus cycle disturbances, but there are virtually no human data. We examined the association of 25-hydroxyvitamin D (25(OH)D) (a biomarker for vitamin D status) with menstrual cycle characteristics. METHODS:Women aged 35-44 were randomly selected from...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Jukic AM,Steiner AZ,Baird DD

更新日期：2015-03-11 00:00:00

abstract：BACKGROUND:Despite significant advances in contraceptive options for women, vasectomy and condoms are the only options available for male contraception. Due to this limitation, the burden of contraception resides on the shoulders of females only. Therefore, there is an urgent need to develop a safe, effective and rever...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Chauhan A,Thaper D,Prabha V

更新日期：2020-09-30 00:00:00

abstract：:Preimplantation embryo development involves four stages: fertilization, cell cleavage, morula and blastocyst formation. During these stages, maternal and zygotic epigenetic factors play crucial roles. The gene expression profile is changed dramatically, chromatin is modified and core histone elements undergo significa...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Shi L,Wu J

更新日期：2009-06-05 00:00:00

abstract：:Although much is known about the reproductive biology of pond-breeding frogs, there is comparatively little information about terrestrial-breeding anurans, a highly successful and diverse group. This study investigates the activation and in vitro fertilization of eggs of the Puerto Rican coqui frog obtained by hormona...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Toro E,Michael SF

更新日期：2004-08-05 00:00:00

abstract：BACKGROUND:Women with Polycystic Ovary Syndrome (PCOS) present a heterogeneous reproductive and metabolic profile with an increased lifetime risk of Type 2 Diabetes (T2D). Early biomarkers of these metabolic disturbances in PCOS women have not been identified. The abundance of circulating insulin gene promotor cell-fre...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Udesen PB,Sørensen AE,Joglekar MV,Hardikar AA,Wissing MLM,Englund AM,Dalgaard LT

更新日期：2019-04-05 00:00:00

abstract：BACKGROUND:Through this prospective study, we aimed to explore the change of molecular modification after the transient scrotal hyperthermia on human sperm. METHODS:Ten healthy subjects selected with strict screening criteria underwent testicular warming in a 43 °C water bath for 30 min a day for 10 consecutive days. ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Wu YQ,Rao M,Hu SF,Ke DD,Zhu CH,Xia W

更新日期：2020-08-12 00:00:00

abstract：BACKGROUND:Di(2-ethylhexyl) phthalate (DEHP) exposure reduces embryo implantations, increases embryonic loss, and decreases fetal body weights. However, whether it is associated with the alteration of luteal function remains unknown. Thus, our aim in this study was to explore the effect and mechanism of DEHP on luteal ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Guo M,Lai L,Zong T,Lin Y,Yang B,Zhang L,Li M,Kuang H

更新日期：2015-03-03 00:00:00

abstract：BACKGROUND:Macrophage migration inhibitory factor (MIF) has special pro-inflammatory roles, affecting the functions of macrophages and lymphocytes and counter-regulating the effects of glucocorticoids on the immune response. The conspicuous expression of MIF during human implantation and early embryonic development als...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Faria MR,Hoshida MS,Ferro EA,Ietta F,Paulesu L,Bevilacqua E

更新日期：2010-08-04 00:00:00

abstract：BACKGROUND:L-carnitine (LC), and its acetylated form, acetyl L-carnitine (ALC), have immense functional capabilities to regulate the oxidative and metabolic status of the female reproductive system. The vulnerability of this system to free radicals demand for advanced strategies to combat them. For this purpose, the 'q...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Agarwal A,Sengupta P,Durairajanayagam D

更新日期：2018-01-26 00:00:00