Spatiotemporal patterns of macrophage migration inhibitory factor (Mif) expression in the mouse placenta.

abstract：:Trophoblast cells are unique because they are one of the few mammalian cell types that do not express major histocompatibility complex (MHC) class II antigens, either constitutively or after exposure to IFN-gamma. The absence of MHC class II antigen expression on trophoblast cells has been postulated to be one of the ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Murphy SP,Choi JC,Holtz R

更新日期：2004-07-05 00:00:00

abstract：BACKGROUND:Alpha 2 macroglobulin (A2M; also known as ovostatin), a homotetrameric protein with four disulfide-linked subunits, has the unique feature of inactivating/inhibiting most known proteases including serine-, threonine-, cysteine-, aspartic- and metalloproteases. In chickens, A2M has been identified and charact...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Lim W,Jeong W,Kim JH,Lee JY,Kim J,Bazer FW,Han JY,Song G

更新日期：2011-10-07 00:00:00

abstract：:The present study evaluates the participation of the vagus nerve in pre-pubertal rats with unilateral ovariectomy on puberty onset, and on progesterone, testosterone and estradiol serum levels, and the compensatory responses of the ovary. Unilateral vagotomy did not modify the onset of puberty in unilaterally ovariect...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Morales L,Ricardo B,Bolaños A,Chavira R,Domínguez R

更新日期：2007-06-13 00:00:00

abstract：BACKGROUND:17alpha-Estradiol has been considered as the hormonally inactive isomer of 17beta-estradiol. Recently, nongenomic (smooth muscle relaxation) and genomic (light estrogenic activity) effects of 17alpha-estradiol have been reported, but no reports have yet determined its possible antiestrogenic activity. Theref...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Perusquía M,Navarrete E

更新日期：2005-07-21 00:00:00

abstract：BACKGROUND:The in vitro maturation (IVM) technique has physical and financial benefits, but a lower efficiency and outcome that is still unclear whether it is related to polycystic ovary syndrome (PCOS) itself or the IVM procedure. In this study, we analyzed the clinical and laboratory outcomes of an optimized IVM prot...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Elshewy N,Ji D,Zhang Z,Chen D,Chen B,Xue R,Wu H,Wang J,Zhou P,Cao Y

更新日期：2020-07-15 00:00:00

abstract：BACKGROUND:Puberty onset is a complex, organized biological process with multilevel regulation, and its physiopathological mechanisms are yet to be elucidated. RFRP-3, the mammalian ortholog to gonadotropin-inhibitory hormone, is implicated in inhibiting the synthesis and release of gonadotropin in mammals. However, it...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Han X,He Y,Zeng G,Wang Y,Sun W,Liu J,Sun Y,Yu J

更新日期：2017-05-02 00:00:00

abstract：BACKGROUND:Premutation range CGGn repeats of the FMR1 gene denote risk toward primary ovarian insufficiency (POI), also called premature ovarian failure (POF). This prospective cohort study was undertaken to determine if X-chromosome inactivation skew (sXCI) is associated with variations in FMR1 CGG repeat length and, ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Barad DH,Darmon S,Weghofer A,Latham GJ,Filipovic-Sadic,Wang Q,Kushnir VA,Albertini DF,Gleicher N

更新日期：2017-04-28 00:00:00

abstract：BACKGROUND:Gestational diabetes mellitus (GDM) is a common complication in pregnancy that poses a serious threat to the health of both mother and child. While the specific etiology and pathogenesis of this disease are not fully understood, it is thought to arise due to a combination of insulin resistance, inflammation,...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Wang H,Zhou W,She G,Yu B,Sun L

更新日期：2020-05-20 00:00:00

abstract：BACKGROUND:Wolfram Syndrome (WS) is an autosomal recessive disorder characterised by non-autoimmune diabetes mellitus, optic atrophy, cranial diabetes insipidus and sensorineural deafness. Some reports have described hypogonadism in male WS patients. The aim of our study was to find out whether Wfs1 deficient (Wfs1KO) ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Noormets K,Kõks S,Kavak A,Arend A,Aunapuu M,Keldrimaa A,Vasar E,Tillmann V

更新日期：2009-08-10 00:00:00

abstract：BACKGROUND:We found previously that the expression of SET gene was up-regulated in polycystic ovaries. Evidences suggested that SET protein was essential for regulating both the promoter activity of CYP17A1 and the biological activity of P450c17. In this study, we explored whether SET regulated androgen production in p...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Xu B,Gao L,Cui Y,Gao L,Dai X,Li M,Zhang Y,Ma X,Diao F,Liu J

更新日期：2013-02-19 00:00:00

abstract：BACKGROUND:The aim of this study was to compare pregnancy rates in patients undergoing IVF/ICSI with embryo transfer after 4 and 5 days of culture in a closed incubation system with integrated time-lapse imaging. METHODS:Out of n = 2207 in vitro fertilization (IVF)/ intracytoplasmic sperm injection (ICSI) cycles perfo...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Holschbach V,Weigert J,Dietrich JE,Roesner S,Montag M,Strowitzki T,Toth B

更新日期：2017-05-08 00:00:00

abstract：BACKGROUND:Overweight and obese women have been shown to have an increased risk of recurrent miscarriage as well as other adverse reproductive outcomes, but it is yet unclear whether this is due to an effect on the endometrium, embryo or both. The current study employs proteomic analysis to examine for a potential endo...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Metwally M,Preece R,Thomas J,Ledger W,Li TC

更新日期：2014-08-05 00:00:00

abstract：:A recent reassessment of the phylogenetic affinities of cetaceans makes it timely to compare their placentation with that of the artiodactyls. We studied the placentae of two sympatric species of dolphin from the Amazon River Basin, representing two distinct families. The umbilical cord branched to supply a bilobed al...

journal_title：Reproductive biology and endocrinology : RB&E

authors： da Silva VM,Carter AM,Ambrosio CE,Carvalho AF,Bonatelli M,Lima MC,Miglino MA

更新日期：2007-06-28 00:00:00

abstract：BACKGROUND:There is limited literature investigating the effects of body mass index (BMI) and androgen level on in vitro fertilization (IVF) outcomes with a gonadotropin-releasing hormone (GnRH)-antagonist protocol in polycystic ovary syndrome (PCOS). Androgen-related variation in the effect of body mass index (BMI) on...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Yang W,Yang R,Lin M,Yang Y,Song X,Zhang J,Yang S,Song Y,Li J,Pang T,Deng F,Zhang H,Wang Y,Li R,Jiao J

更新日期：2018-11-19 00:00:00

abstract：BACKGROUND:Morphometric and morphokinetic evaluation of in vitro cultured human embryos allows evaluation without time restriction and reduces intra- and inter-observer variability. Even though these technologies have been reported to improve the quality of cleavage stage embryo evaluation during fresh culture, possibl...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Fernandez Gallardo E,Spiessens C,D'Hooghe T,Debrock S

更新日期：2017-10-03 00:00:00

abstract：BACKGROUND:Polycystic ovary syndrome (PCOS) has been recognized as a metabolic disorder, manifested by abdominal obesity, insulin resistance, dyslipidemia and hypertension. Pigment epithelium-derived factor (PEDF), a member of the serine protease inhibitor family, is a pleiotropic protein known for its antiangiogenic, ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Lecke SB,Morsch D,Spritzer PM

更新日期：2013-08-14 00:00:00

abstract：BACKGROUND:Studies suggested that microRNAs influence cellular activities in the uterus including cell differentiation and embryo implantation. In assisted reproduction cycles, luteal phase support, given to improve endometrial characteristics and to facilitate the implantation process, has been a standard practice. Th...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zhao Y,Zacur H,Cheadle C,Ning N,Fan J,Vlahos NF

更新日期：2012-09-06 00:00:00

abstract：BACKGROUND:In early pregnancy, increased plasma levels of the endocannabinoid anandamide (AEA) are associated with miscarriage through mechanisms that might affect the developing placenta or maternal decidua. METHODS:In this study, we compare AEA levels in failed and viable pregnancies with the levels of the trophobla...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Taylor AH,Finney M,Lam PM,Konje JC

更新日期：2011-11-29 00:00:00

abstract：:Recent reports indicate that functional mouse oocytes and sperm can be derived in vitro from somatic cell lines. We hypothesize that in adult human ovaries, mesenchymal cells in the tunica albuginea (TA) are bipotent progenitors with a commitment for both primitive granulosa and germ cells. We investigated ovaries of ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Bukovsky A,Caudle MR,Svetlikova M,Upadhyaya NB

更新日期：2004-04-28 00:00:00

abstract：BACKGROUND:Mammalian oocyte meiotic maturation involves a number of important processes, including spindle assembly and migration, cortical reorganization and polar body extrusion. Numerous proteins contribute to these processes, but it is unknown whether MKlp2 (mitotic kinesin-like protein 2; also called KIF20A), a mi...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Liu J,Wang QC,Cui XS,Wang ZB,Kim NH,Sun SC

更新日期：2013-12-21 00:00:00

abstract：:Although much is known about the reproductive biology of pond-breeding frogs, there is comparatively little information about terrestrial-breeding anurans, a highly successful and diverse group. This study investigates the activation and in vitro fertilization of eggs of the Puerto Rican coqui frog obtained by hormona...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Toro E,Michael SF

更新日期：2004-08-05 00:00:00

abstract：BACKGROUND:Meta-analysis revealed that embryo placement 20 mm from the fundal endometrial surface resulted in higher pregnancy rate, ongoing pregnancy rate, and live birth rate compared with placement 10 mm from the fundal endometrial surface. Pregnancy and implantation rates according to relative position were higher ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Kwon H,Choi DH,Kim EK

更新日期：2015-07-29 00:00:00

abstract：BACKGROUND:The study was designed to test the hypothesis that granulosa cell (GC) gene expression response differs between recombinant FSH and human menopausal gonadotropin (hMG) stimulation regimens. METHODS:Females < 35 years-old undergoing IVF for tubal or male factor infertility were prospectively randomized to on...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Brannian J,Eyster K,Mueller BA,Bietz MG,Hansen K

更新日期：2010-03-12 00:00:00

abstract：BACKGROUND:Low functional ovarian reserve (LFOR) has been associated with hypoandrogenemia and increased embryo aneuploidy, while androgen supplementation has been reported to improve aneuploidy rates. We, therefore, assessed whether in infertile women undergoing in vitro fertilization (IVF) androgen concentrations are...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gleicher N,McCulloh DH,Kushnir VA,Ganguly N,Barad DH,Goldman KN,Kushnir MM,Albertini DF,Grifo JA

更新日期：2015-05-06 00:00:00

abstract：BACKGROUND:Gonadal differentiation in the mammalian fetus involves a complex dose-dependent genetic network. Initiation and progression of fetal ovarian and testicular pathways are accompanied by dynamic expression patterns of thousands of genes. We postulate these expression patterns are regulated by small non-coding ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Torley KJ,da Silveira JC,Smith P,Anthony RV,Veeramachaneni DN,Winger QA,Bouma GJ

更新日期：2011-01-11 00:00:00

abstract：BACKGROUND:Claudin-4 (CLDN4) is one of several proteins that act as molecular mediators of embryo implantation. Recently, we examined immunolabeling of leukemia inhibitory factor (LIF) in the endometrial tissue of 52 IVF patients, and found that LIF staining intensity was strongly correlated with successful pregnancy i...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Serafini PC,Silva ID,Smith GD,Motta EL,Rocha AM,Baracat EC

更新日期：2009-04-19 00:00:00

abstract：BACKGROUND:The World Health Organization (WHO) international body mass index (BMI) cut-off points defining pre-pregnancy BMI categories in the Institute of Medicine (IOM) guidelines are not directly applicable to Asians. We aimed to define the optimal gestational weight gain (GWG) for the Korean population based on Asi...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Choi SK,Lee G,Kim YH,Park IY,Ko HS,Shin JC

更新日期：2017-08-22 00:00:00

abstract：BACKGROUND:Endocrine mechanisms governing canine reproductive function remain still obscure. Progesterone (P4) of luteal origin is required for maintenance of pregnancy. Corpora lutea (CL) are gonadotrop-independent during the first third of dioestrus; afterwards prolactin (PRL) is the primary luteotropic factor. Inter...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Kowalewski MP,Michel E,Gram A,Boos A,Guscetti F,Hoffmann B,Aslan S,Reichler I

更新日期：2011-08-03 00:00:00

abstract：:A majority of common metabolic diseases can result in excessive lipolysis, leading to elevated levels of non-esterified fatty acids (NEFAs) in the body fluids. In females, increased NEFA levels in the follicular fluid markedly alter the functions of intrafollicular cells such as granulosa cells (GCs) and oocytes. Ther...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Baddela VS,Sharma A,Vanselow J

更新日期：2020-06-06 00:00:00

abstract：BACKGROUND:Relaxin levels in seminal plasma have been associated with positive effects on sperm motility and quality, and thus having potential roles in male fertility. However, the origin of seminal relaxin, within the male reproductive tract, and the moment of its release in the vicinity of spermatozoa remain unclear...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Feugang JM,Greene JM,Sanchez-Rodríguez HL,Stokes JV,Crenshaw MA,Willard ST,Ryan PL

更新日期：2015-05-20 00:00:00