Extended letrozole regimen versus clomiphene citrate for superovulation in patients with unexplained infertility undergoing intrauterine insemination: a randomized controlled trial.

abstract：BACKGROUND:Gonadal differentiation in the mammalian fetus involves a complex dose-dependent genetic network. Initiation and progression of fetal ovarian and testicular pathways are accompanied by dynamic expression patterns of thousands of genes. We postulate these expression patterns are regulated by small non-coding ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Torley KJ,da Silveira JC,Smith P,Anthony RV,Veeramachaneni DN,Winger QA,Bouma GJ

更新日期：2011-01-11 00:00:00

abstract：BACKGROUND:hCG is a term referring to 4 independent molecules, each produced by separate cells and each having completely separate functions. These are hCG produced by villous syncytiotrophoblast cells, hyperglycosylated hCG produced by cytotrophoblast cells, free beta-subunit made by multiple primary non-trophoblastic...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Cole LA

更新日期：2010-08-24 00:00:00

abstract：BACKGROUND:To assess the amount of variability in ovarian follicular growth rate and maximum follicular diameter related to different centers, women and cycles of the same women in a multicenter observational study of follicular growth. METHODS:Secondary analysis of a prospective cohort study from eight centers in Eur...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Mikolajczyk RT,Stanford JB,Ecochard R

更新日期：2008-12-10 00:00:00

abstract：BACKGROUND:Relaxin levels in seminal plasma have been associated with positive effects on sperm motility and quality, and thus having potential roles in male fertility. However, the origin of seminal relaxin, within the male reproductive tract, and the moment of its release in the vicinity of spermatozoa remain unclear...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Feugang JM,Greene JM,Sanchez-Rodríguez HL,Stokes JV,Crenshaw MA,Willard ST,Ryan PL

更新日期：2015-05-20 00:00:00

abstract：BACKGROUND:With infertility populations rapidly aging, treatments improving pregnancy chances assume increasing clinical importance. Dehydroepiandrosterone (DHEA) has been reported to improve pregnancy rates and lower miscarriage rates in women with diminished ovarian function. This study was planned to evaluate whethe...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Tartagni M,Cicinelli MV,Baldini D,Tartagni MV,Alrasheed H,DeSalvia MA,Loverro G,Montagnani M

更新日期：2015-03-09 00:00:00

abstract：BACKGROUND:Stereology is an established method to extrapolate three-dimensional quantities from two-dimensional images. It was applied to placentation in the mouse, but not yet for other rodents. Herein, we provide the first study on quantitative placental development in a sigmodontine rodent species with relatively si...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Favaron PO,Mess AM,de Oliveira MF,Gabory A,Miglino MA,Chavatte-Palmer P,Tarrade A

更新日期：2013-02-21 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated that progestin-primed ovarian stimulation (PPOS) protocol was a feasible and efficient method in in vitro fertilization (IVF) cycle. However, its application in women with advanced age has not been determined yet. The purpose of this study was to investigate its efficacy in...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Peng Q,Cao X,Wang J,Wang L,Xu J,Ji X,Liu S,Zhu J,Dong X

更新日期：2019-11-09 00:00:00

abstract：BACKGROUND:Di(2-ethylhexyl) phthalate (DEHP) exposure reduces embryo implantations, increases embryonic loss, and decreases fetal body weights. However, whether it is associated with the alteration of luteal function remains unknown. Thus, our aim in this study was to explore the effect and mechanism of DEHP on luteal ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Guo M,Lai L,Zong T,Lin Y,Yang B,Zhang L,Li M,Kuang H

更新日期：2015-03-03 00:00:00

abstract：BACKGROUND:Anti-thyroid antibodies (ATA), even if not associated with thyroid dysfunction, are suspected to cause poorer outcome of in vitro fertilization (IVF). METHODS:We retrospectively analyzed: (a) the prevalence of ATA in euthyroid infertile women, (b) IVF outcome in euthyroid, ATA+ patients, and (c) the effect ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Revelli A,Casano S,Piane LD,Grassi G,Gennarelli G,Guidetti D,Massobrio M

更新日期：2009-11-27 00:00:00

abstract：BACKGROUND:We demonstrated that E2 conjugated to BSA (E2BSA) induces a rapid membrane-initiated inhibition of LH secretion followed hours later by a slight increase in LH secretion. Whether these actions of E2BSA are restricted to the pituitary gland and whether the membrane-initiated pathway of E2BSA contributes to th...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Arreguin-Arevalo JA,Ashley RL,Wagenmaker ER,Oakley AE,Karsch FJ,Nett TM

更新日期：2010-05-10 00:00:00

abstract：:During the follicular phase of the primate menstrual cycle, a single follicle usually matures to the preovulatory stage and releases its oocyte for fertilization and the potential establishment of pregnancy. In assisted reproductive technology procedures, it is desirable to override the natural process of follicle sel...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zeleznik AJ

更新日期：2004-06-16 00:00:00

abstract：BACKGROUND:Embryo selection has been an integral feature of in vitro fertilization (IVF) almost since its inception. Since the advent of extended blastocyst stage embryo culture, and especially with increasing popularity of elective single embryo transfer (eSET), the concept of embryo selection has increasingly become ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gleicher N,Kushnir VA,Barad DH

更新日期：2015-01-11 00:00:00

abstract：BACKGROUND:Serum leptin levels are augmented in obese infertile men and in men with azoospermia. They also correlate inversely with sperm concentration, motility and normal forms. The mechanisms underlying the adverse effects of excess leptin on male reproductive function remain unclear. The present study aimed to eval...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Wang X,Zhang X,Hu L,Li H

更新日期：2018-05-31 00:00:00

abstract：BACKGROUND:Progesterone plays an important role in the proliferation and differentiation of human endometrial cells (hECs). Large-dose treatment with progesterone has been used for treatment of endometrial proliferative disorders. However, the mechanisms behind remain unknown. METHODS:To investigate the role of cyclin...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Tang L,Zhang Y,Pan H,Luo Q,Zhu XM,Dong MY,Leung PC,Sheng JZ,Huang HF

更新日期：2009-12-07 00:00:00

abstract：BACKGROUND:In animals, low levels of vitamin D are associated with estrus cycle disturbances, but there are virtually no human data. We examined the association of 25-hydroxyvitamin D (25(OH)D) (a biomarker for vitamin D status) with menstrual cycle characteristics. METHODS:Women aged 35-44 were randomly selected from...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Jukic AM,Steiner AZ,Baird DD

更新日期：2015-03-11 00:00:00

abstract：BACKGROUND:Despite being born with a significant number of primordial cells which representing the ancestor cells of the germ-line, women experience a depletion of ovarian reserve and sub-fertility mid-way into their healthy lives. The poor ovarian response is a substantial limiting factor amplified with higher materna...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Khan HL,Bhatti S,Suhail S,Gul R,Awais A,Hamayun H,Enver F,Abbas S,Hassan Z,Nisar R,Sardar S,Asif W

更新日期：2019-02-11 00:00:00

abstract：BACKGROUND:The full maturational capability of mammalian oocytes is accompanied by nuclear and cytoplasmic modifications, which are associated with proliferation and differentiation of surrounding cumulus cells. These events are regulated on molecular level by the expression of target genes involved in signal transduct...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Budna J,Rybska M,Ciesiółka S,Bryja A,Borys S,Kranc W,Wojtanowicz-Markiewicz K,Jeseta M,Sumelka E,Bukowska D,Antosik P,Brüssow KP,Bruska M,Nowicki M,Zabel M,Kempisty B

更新日期：2017-06-02 00:00:00

abstract：BACKGROUND:Adults with polycystic ovary syndrome (PCOS) can have multiple metabolic abnormalities. However, studies in the adolescent population are still limited and these results seem to vary widely. This study was to investigate the metabolic abnormalities in adolescents with PCOS in South China and the potential ri...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Huang J,Ni R,Chen X,Huang L,Mo Y,Yang D

更新日期：2010-11-17 00:00:00

abstract：BACKGROUND:The published results regarding lymphocytes immunotherapy for unexplained recurrent miscarriage (uRM) patients are conflicting due to different screening criteria and therapeutic protocols. The objective of the present study is to evaluate the effectiveness of immunotherapy using low-dose lymphocytes in pati...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Liu M,Zhen X,Song H,Chen J,Sun X,Li X,Zhou J,Yan G,Ding L,Sun H

更新日期：2017-12-16 00:00:00

abstract：BACKGROUND:Women with Polycystic Ovary Syndrome (PCOS) present a heterogeneous reproductive and metabolic profile with an increased lifetime risk of Type 2 Diabetes (T2D). Early biomarkers of these metabolic disturbances in PCOS women have not been identified. The abundance of circulating insulin gene promotor cell-fre...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Udesen PB,Sørensen AE,Joglekar MV,Hardikar AA,Wissing MLM,Englund AM,Dalgaard LT

更新日期：2019-04-05 00:00:00

abstract：BACKGROUND:The objective was to determine the effect of prepartum diets supplemented with rolled canola seed (high in oleic acid) or sunflower seed (high in linoleic acid) on luteinizing hormone (LH) pulsatility and gonadotropin releasing hormone (GnRH)-induced LH release during early postpartum. METHODS:Thirty-one pr...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Salehi R,Colazo MG,Oba M,Ambrose DJ

更新日期：2015-07-03 00:00:00

abstract：BACKGROUND:The transformation of endometrium into decidua is essential for normal implantation of the blastocyst. However, the post-transcriptional regulation and the miRNAs involved in decidualization remain poorly understood. Here, we examined microRNA-181a (miR-181a) expression in decidualized human endometrial stro...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zhang Q,Zhang H,Jiang Y,Xue B,Diao Z,Ding L,Zhen X,Sun H,Yan G,Hu Y

更新日期：2015-03-26 00:00:00

abstract：BACKGROUND:In several species, considerably higher levels of estradiol-17 (E2) are synthesized in the CL. E2 has been suggested to participate in the regulation of luteal steroidogenesis and luteal cell morphology. In pregnant rats, several experiments have been carried out to examine the effects of inhibition of lutea...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Tripathy S,Asaithambi K,Jayaram P,Medhamurthy R

更新日期：2016-04-12 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) is a common endocrine disorder, affecting 9-18% of women in reproductive age that causes hyperandrogenism and infertility due to dysfunctional follicular maturation and anovulation. The etiology of PCOS is still poorly known, and information from experimental animal models may help imp...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Paixão L,Ramos RB,Lavarda A,Morsh DM,Spritzer PM

更新日期：2017-02-10 00:00:00

abstract：BACKGROUND:The G protein-coupled estrogen receptor (GPER) is thought to be involved in non-genomic estrogen responses as well as processes such as cell proliferation and migration. In this study, we analyzed GPER expression patterns from endometriosis samples and normal endometrial tissue samples and compared these exp...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Samartzis N,Samartzis EP,Noske A,Fedier A,Dedes KJ,Caduff R,Fink D,Imesch P

更新日期：2012-04-20 00:00:00

abstract：BACKGROUND:Flow cytometric sorting can be used to separate sperm based on sex chromosome content. Differential fluorescence emitted by stained X- vs. Y-chromosome-bearing sperm enables sorting and collection of samples enriched in either X- or Y-bearing sperm for use to influence the likelihood that the offspring will ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Karabinus DS,Marazzo DP,Stern HJ,Potter DA,Opanga CI,Cole ML,Johnson LA,Schulman JD

更新日期：2014-11-24 00:00:00

abstract：BACKGROUND:Endometriosis is a well-known cause of infertility, and the anti-Mullerian hormone (AMH) is an accepted biomarker of ovarian reserve and response to artificial reproductive technology procedures. The present study was a prospective analysis of age-dependent AMH serum concentration in women with bilateral and...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Nieweglowska D,Hajdyla-Banas I,Pitynski K,Banas T,Grabowska O,Juszczyk G,Ludwin A,Jach R

更新日期：2015-11-24 00:00:00

abstract：BACKGROUND:Hatching is crucial for mammalian embryo implantation, since difficulties during this process can lead to implantation failure, ectopic pregnancy and consequent infertility. Despite years of intensive researches, how internal and external factors affecting embryo hatch are still largely unclear. METHODS:The...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zhan S,Cao S,Du H,Sun Y,Li L,Ding C,Zheng H,Huang J

更新日期：2018-04-21 00:00:00

abstract：BACKGROUND:In natural cycles, women conceive when intercourse takes place during a six-day period ending on the day of ovulation. The current practice in intrauterine insemination (IUI) cycles is to perform the IUI 24-36 hours after the hCG administration, when the ovulation is already imminent. In this study hCG was a...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Järvelä IY,Tapanainen JS,Martikainen H

更新日期：2010-02-23 00:00:00

abstract：BACKGROUND:Hyperandrogenic conditions have been associated with a high prevalence of endometrial pathologies related to cell survival. However, the action of androgens on proliferation and apoptosis in endometrial cells is poorly understood. Therefore, the aim of the present study was to evaluate the effect of androste...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Maliqueo MA,Quezada S,Clementi M,Bacallao K,Anido M,Johnson C,Vega M

更新日期：2004-12-10 00:00:00