Involvement of cyclin B1 in progesterone-mediated cell growth inhibition, G2/M cell cycle arrest, and apoptosis in human endometrial cell.

abstract：:Cloning by nuclear transfer using mammalian somatic cells has enormous potential application. However, somatic cloning has been inefficient in all species in which live clones have been produced. High abortion and fetal mortality rates are commonly observed. These developmental defects have been attributed to incomple...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Tian XC,Kubota C,Enright B,Yang X

更新日期：2003-11-13 00:00:00

abstract：:Although Calbindin-D9k (CaBP-9k), a cytosolic calcium binding protein which has calcium binding sites, is expressed in various tissues, i.e., intestine, uterus, and placenta, potential roles of this gene and its protein are not clearly understood. Uterine CaBP-9k may be involved in controlling myometrial activity rela...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Choi KC,Leung PC,Jeung EB

更新日期：2005-11-16 00:00:00

abstract：:The endometrium undergoes cyclic remodelling throughout the menstrual cycle in preparation for embryo implantation which occurs in a short window during the mid-secretory phase. It is during this short 'receptive window' that the endometrial luminal epithelium acquires adhesive capacity permitting blastocysts firm adh...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Santos LL,Ling CK,Dimitriadis E

更新日期：2020-12-14 00:00:00

abstract：BACKGROUND:A limited number of publications have assessed the prevalence of hypertension (HTN) in polycystic ovary syndrome (PCOS) patients with inconclusive results. Since in general populations the occurrence of hypertension is related to age per se, we investigated the prevalence (P) / relative risk (RR) of HTN in p...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Amiri M,Ramezani Tehrani F,Behboudi-Gandevani S,Bidhendi-Yarandi R,Carmina E

更新日期：2020-03-17 00:00:00

abstract：BACKGROUND:New anticancer treatments have increased survival rates for cancer patients, but often at the cost of sterility. Several strategies are currently available for preserving fertility. However, the chances of achieving a pregnancy with one technique are still limited. A combination of methods is therefore recom...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Dittrich R,Lotz L,Mueller A,Hoffmann I,Wachter DL,Amann KU,Beckmann MW,Hildebrandt T

更新日期：2013-03-05 00:00:00

abstract：BACKGROUND:Despite being born with a significant number of primordial cells which representing the ancestor cells of the germ-line, women experience a depletion of ovarian reserve and sub-fertility mid-way into their healthy lives. The poor ovarian response is a substantial limiting factor amplified with higher materna...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Khan HL,Bhatti S,Suhail S,Gul R,Awais A,Hamayun H,Enver F,Abbas S,Hassan Z,Nisar R,Sardar S,Asif W

更新日期：2019-02-11 00:00:00

abstract：BACKGROUND:Several medical conditions can affect and disrupt human sexuality. The alteration of sexuality in these medical conditions often hinder effective communication and empathy between the patients and their sexual partners because of cultural attitudes, social norms and negative feelings such as anxiety and guil...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Amidu N,Owiredu WK,Woode E,Appiah R,Quaye L,Gyasi-Sarpong CK

更新日期：2010-10-13 00:00:00

abstract：BACKGROUND:There is limited literature investigating the effects of body mass index (BMI) and androgen level on in vitro fertilization (IVF) outcomes with a gonadotropin-releasing hormone (GnRH)-antagonist protocol in polycystic ovary syndrome (PCOS). Androgen-related variation in the effect of body mass index (BMI) on...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Yang W,Yang R,Lin M,Yang Y,Song X,Zhang J,Yang S,Song Y,Li J,Pang T,Deng F,Zhang H,Wang Y,Li R,Jiao J

更新日期：2018-11-19 00:00:00

abstract：BACKGROUND:It is not well established whether the increased number of leukocytes in the seminal fluid impairs the outcomes of assisted reproductive technology (ART). This investigation analysed the outcomes of the intracytoplasmic sperm injection (ICSI) and intracytoplasmic morphologically selected sperm injection (IMS...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Cavagna M,Oliveira JB,Petersen CG,Mauri AL,Silva LF,Massaro FC,Baruffi RL,Franco JG Jr

更新日期：2012-06-15 00:00:00

abstract：BACKGROUND:Di(2-ethylhexyl) phthalate (DEHP) exposure reduces embryo implantations, increases embryonic loss, and decreases fetal body weights. However, whether it is associated with the alteration of luteal function remains unknown. Thus, our aim in this study was to explore the effect and mechanism of DEHP on luteal ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Guo M,Lai L,Zong T,Lin Y,Yang B,Zhang L,Li M,Kuang H

更新日期：2015-03-03 00:00:00

abstract：BACKGROUND:During the estrous cycle, the rat uterine endometrium undergoes many changes such as cell proliferation and apoptosis. If implantation occurs, stromal cells differentiate into decidual cells and near the end of pregnancy, a second wave of apoptosis occurs. This process called decidual regression, is tightly ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Caron PL,Fréchette-Frigon G,Shooner C,Leblanc V,Asselin E

更新日期：2009-08-05 00:00:00

abstract：BACKGROUND:Despite the clinical outcomes of ovarian stimulation with either GnRH-agonist or GnRH-antagonist analogues for in vitro fertilization (IVF) being well analysed, the effect of analogues on oocyte/embryo quality and embryo development is still not known in detail. The aim of this case-control study was to comp...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Murber A,Fancsovits P,Ledó N,Gilán ZT,Rigó J Jr,Urbancsek J

更新日期：2009-09-25 00:00:00

abstract：BACKGROUND:Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder associated with ovulatory dysfunction, abdominal obesity, hyperandrogenism, hypertension, and insulin resistance. METHODS:Our objectives in this study were (1) to estimate sympathetic-adrenal medullary (SAM) activity by measuring...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Stener-Victorin E,Ploj K,Larsson BM,Holmäng A

更新日期：2005-09-07 00:00:00

abstract：BACKGROUND:With infertility populations rapidly aging, treatments improving pregnancy chances assume increasing clinical importance. Dehydroepiandrosterone (DHEA) has been reported to improve pregnancy rates and lower miscarriage rates in women with diminished ovarian function. This study was planned to evaluate whethe...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Tartagni M,Cicinelli MV,Baldini D,Tartagni MV,Alrasheed H,DeSalvia MA,Loverro G,Montagnani M

更新日期：2015-03-09 00:00:00

abstract：BACKGROUND:Bovine luteal parenchymal cells express class II major histocompatibility complex (MHC) molecules and stimulate class II MHC-dependent activation of T cells in vitro. The ability of a class II MHC-expressing cell type to elicit a response from T cells in vivo is also dependent on expression of costimulatory ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Cannon MJ,Davis JS,Pate JL

更新日期：2007-01-31 00:00:00

abstract：BACKGROUND:We examined the presence and function of tachykinins and the tachykinin-degrading enzymes neprilysin (NEP) and neprilysin-2 (NEP2) in human spermatozoa. METHODS:Freshly ejaculated semen was collected from forty-eight normozoospermic human donors. We analyzed the expression of substance P, neurokinin A, neur...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Pinto FM,Ravina CG,Subiran N,Cejudo-Román A,Fernández-Sánchez M,Irazusta J,Garrido N,Candenas L

更新日期：2010-08-26 00:00:00

abstract：BACKGROUND:The transformation of endometrium into decidua is essential for normal implantation of the blastocyst. However, the post-transcriptional regulation and the miRNAs involved in decidualization remain poorly understood. Here, we examined microRNA-181a (miR-181a) expression in decidualized human endometrial stro...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zhang Q,Zhang H,Jiang Y,Xue B,Diao Z,Ding L,Zhen X,Sun H,Yan G,Hu Y

更新日期：2015-03-26 00:00:00

abstract：:Cloning mammals by nuclear transfer is a powerful technique that is quickly advancing the development of genetically defined animal models. However, the overall efficiency of nuclear transfer is still very low and several hurdles remain before the power of this technique will be fully harnessed. Among these hurdles in...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Li X,Li Z,Jouneau A,Zhou Q,Renard JP

更新日期：2003-11-07 00:00:00

abstract：BACKGROUND:Leukocytes represent the predominant source of reactive oxygen species both in seminal plasma and in sperm suspensions and have been demonstrated to negatively influence sperm function and fertilization rate in assisted reproduction procedures. Peroxidase test is the standard method recommended by WHO to det...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Ricci G,Perticarari S,Boscolo R,Simeone R,Martinelli M,Fischer-Tamaro L,Guaschino S,Presani G

更新日期：2009-11-19 00:00:00

abstract：BACKGROUND:Decidualization is a prerequisite for successful implantation and the establishment of pregnancy. A critical role of impaired decidualization in subfertility has been established. In human endometrial stromal cells (hESCs), Krüppel-like factor 12 (KLF12) and Nur77 are novel regulators of decidualization. We ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Huang C,Jiang Y,Zhou J,Yan Q,Jiang R,Cheng X,Xing J,Ding L,Sun J,Yan G,Sun H

更新日期：2017-03-31 00:00:00

abstract：BACKGROUND:The purpose of this study was to test the hypothesis that menstruation is associated with a higher concentration of endometrial cells in peritoneal fluid(PF) and with increased white and red blood cell concentration in PF when compared to nonmenstrual phases of the cycle. METHODS:PF was obtained at laparosc...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Bokor A,Debrock S,Drijkoningen M,Goossens W,Fülöp V,D'Hooghe T

更新日期：2009-10-30 00:00:00

abstract：BACKGROUND:Considering that clinical trial studies are limited in polycystic ovary syndrome (PCOS) patients, and there is no consensus on an optimum endometrial preparation protocol for frozen embryo transfer (FET), the present study was designed as a randomized clinical trial to compare the reproductive outcomes follo...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Hosseini-Najarkolaei A,Moini A,Kashani L,Farid Mojtahedi M,Hosseini-Najarkolaee E,Salehi E

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND:Male factor infertility is quite common as 30-50% of infertility cases are due to sperm defects. The high sperm DNA fragmentation is one of the causes of male factor infertility. Many factors cause sperm DNA fragmentation and could be testicular or post-testicular. The purpose of this study was to assess rel...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Al Omrani B,Al Eisa N,Javed M,Al Ghedan M,Al Matrafi H,Al Sufyan H

更新日期：2018-05-19 00:00:00

abstract：BACKGROUND:This study was aimed at screening out the potential key genes and pathways associated with gestational diabetes mellitus (GDM). METHODS:The GSE70493 dataset used for this study was obtained from the Gene Expression Omnibus database. Differentially expressed genes (DEGs) in the placental tissue of women with...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Wang Y,Yu H,Liu F,Song X

更新日期：2019-11-29 00:00:00

abstract：BACKGROUND:The aim of this study was to determine the relationship between a purported luteinizing hormone/chorionic gonadotropin (LHCGR) high function polymorphism (rs4539842/insLQ) and outcome to controlled ovarian hyperstimulation (COH). METHODS:This was a prospective study of 172 patients undergoing COH at the Fer...

journal_title：Reproductive biology and endocrinology : RB&E

authors： O'Brien TJ,Kalmin MM,Harralson AF,Clark AM,Gindoff I,Simmens SJ,Frankfurter D,Gindoff P

更新日期：2013-07-25 00:00:00

abstract：BACKGROUND:Testicular microliths are calcifications found within the seminiferous tubules. In humans, testicular microlithiasis (TM) has an unknown etiology but may be significantly associated with testicular germ cell tumors. Factors inducing microlith development may also, therefore, act as susceptibility factors for...

journal_title：Reproductive biology and endocrinology : RB&E

authors： O'Shaughnessy PJ,Monteiro A,Verhoeven G,De Gendt K,Abel MH

更新日期：2009-08-27 00:00:00

abstract：BACKGROUND:Polycystic ovary syndrome (PCOS) has been recognized as a metabolic disorder, manifested by abdominal obesity, insulin resistance, dyslipidemia and hypertension. Pigment epithelium-derived factor (PEDF), a member of the serine protease inhibitor family, is a pleiotropic protein known for its antiangiogenic, ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Lecke SB,Morsch D,Spritzer PM

更新日期：2013-08-14 00:00:00

abstract：BACKGROUND:The alterations of the glutathione peroxidase enzyme complex system occur in physiological conditions such as aging and oxidative stress consequent to strenuous exercise. METHODS:Authors optimize the spectrophotometric method to measure glutathione peroxidase activity in rat red blood cell membranes. RESUL...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gallo G,Martino G

更新日期：2009-01-26 00:00:00

abstract：BACKGROUND:Intracytoplasmic morphologically selected sperm injection (IMSI) is still proposed and employed in the clinical practice to improve the reproductive outcome in infertile couples scheduled for conventional intracytoplasmic sperm injection (cICSI). The aim of the current randomized controlled trial (RCT) was t...

journal_title：Reproductive biology and endocrinology : RB&E

authors： La Sala GB,Nicoli A,Fornaciari E,Falbo A,Rondini I,Morini D,Valli B,Villani MT,Palomba S

更新日期：2015-08-27 00:00:00

abstract：BACKGROUND:High levels of dopamine (DA) were described in human ovary and recently evidence for DA receptors in granulosa and luteal cells has been provided, as well. However, neither the full repertoire of ovarian receptors for DA, nor their specific role, is established. Human granulosa cells (GCs) derived from women...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Rey-Ares V,Lazarov N,Berg D,Berg U,Kunz L,Mayerhofer A

更新日期：2007-10-25 00:00:00