Oncofertility: combination of ovarian stimulation with subsequent ovarian tissue extraction on the day of oocyte retrieval.

abstract：BACKGROUND:Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder associated with ovulatory dysfunction, abdominal obesity, hyperandrogenism, hypertension, and insulin resistance. METHODS:Our objectives in this study were (1) to estimate sympathetic-adrenal medullary (SAM) activity by measuring...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Stener-Victorin E,Ploj K,Larsson BM,Holmäng A

更新日期：2005-09-07 00:00:00

abstract：BACKGROUND:TGF-beta is a multifunctional growth factor involved in regulating a variety of cellular activities. Unlike mammals, the function of TGF-beta in the reproduction of lower vertebrates, such as fish, is not clear. Recently, we showed that TGF-beta1 inhibits gonadotropin- and 17alpha, 20beta-dihydroxyprogestero...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Kohli G,Clelland E,Peng C

更新日期：2005-09-30 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated that progestin-primed ovarian stimulation (PPOS) protocol was a feasible and efficient method in in vitro fertilization (IVF) cycle. However, its application in women with advanced age has not been determined yet. The purpose of this study was to investigate its efficacy in...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Peng Q,Cao X,Wang J,Wang L,Xu J,Ji X,Liu S,Zhu J,Dong X

更新日期：2019-11-09 00:00:00

abstract：BACKGROUND:Considering that clinical trial studies are limited in polycystic ovary syndrome (PCOS) patients, and there is no consensus on an optimum endometrial preparation protocol for frozen embryo transfer (FET), the present study was designed as a randomized clinical trial to compare the reproductive outcomes follo...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Hosseini-Najarkolaei A,Moini A,Kashani L,Farid Mojtahedi M,Hosseini-Najarkolaee E,Salehi E

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND:Intracytoplasmic morphologically selected sperm injection (IMSI) is still proposed and employed in the clinical practice to improve the reproductive outcome in infertile couples scheduled for conventional intracytoplasmic sperm injection (cICSI). The aim of the current randomized controlled trial (RCT) was t...

journal_title：Reproductive biology and endocrinology : RB&E

authors： La Sala GB,Nicoli A,Fornaciari E,Falbo A,Rondini I,Morini D,Valli B,Villani MT,Palomba S

更新日期：2015-08-27 00:00:00

abstract：BACKGROUND:Adults with polycystic ovary syndrome (PCOS) can have multiple metabolic abnormalities. However, studies in the adolescent population are still limited and these results seem to vary widely. This study was to investigate the metabolic abnormalities in adolescents with PCOS in South China and the potential ri...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Huang J,Ni R,Chen X,Huang L,Mo Y,Yang D

更新日期：2010-11-17 00:00:00

abstract：BACKGROUND:Dehydroepinadrosterone (DHEA) supplementation improves pregnancy chances in women with diminished ovarian reserve (DOR), by possibly reducing aneuploidy. Since a large majority of spontaneous miscarriages are associated with aneuploidy, one can speculate that DHEA supplementation may also reduce miscarriage ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gleicher N,Ryan E,Weghofer A,Blanco-Mejia S,Barad DH

更新日期：2009-10-07 00:00:00

abstract：BACKGROUND:Sperm of poor quality can negatively affect embryo development to the blastocyst stage. The aim of this comparative prospective randomized study was to evaluate the role of an intracytoplasmic morphologically selected sperm injection (IMSI) in the same infertile couples included in the programme of intracyto...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Knez K,Zorn B,Tomazevic T,Vrtacnik-Bokal E,Virant-Klun I

更新日期：2011-08-29 00:00:00

abstract：:Fertilin alpha (ADAM-1) and beta (ADAM-2) are integral membrane proteins of the ADAM family that form a fertilin complex involved in key steps of the sperm-oocyte membrane interaction. In the present work, we analyzed the presence of ADAM-1 and ADAM-2 mRNAs, the spermatozoa proteins' processing and their sub-cellular ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Fàbrega A,Guyonnet B,Dacheux JL,Gatti JL,Puigmulé M,Bonet S,Pinart E

更新日期：2011-06-30 00:00:00

abstract：:Although Calbindin-D9k (CaBP-9k), a cytosolic calcium binding protein which has calcium binding sites, is expressed in various tissues, i.e., intestine, uterus, and placenta, potential roles of this gene and its protein are not clearly understood. Uterine CaBP-9k may be involved in controlling myometrial activity rela...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Choi KC,Leung PC,Jeung EB

更新日期：2005-11-16 00:00:00

abstract：BACKGROUND:The transformation of endometrium into decidua is essential for normal implantation of the blastocyst. However, the post-transcriptional regulation and the miRNAs involved in decidualization remain poorly understood. Here, we examined microRNA-181a (miR-181a) expression in decidualized human endometrial stro...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zhang Q,Zhang H,Jiang Y,Xue B,Diao Z,Ding L,Zhen X,Sun H,Yan G,Hu Y

更新日期：2015-03-26 00:00:00

abstract：BACKGROUND:Polo-like kinase 1 (Plk1), as a characteristic regulator in meiosis, organizes multiple biological events of cell division. Although Plk1 has been implicated in various functions in somatic cell mitotic processes, considerably less is known regarding its function during the transition from metaphase I (MI) t...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zhang Z,Chen C,Ma L,Yu Q,Li S,Abbasi B,Yang J,Rui R,Ju S

更新日期：2017-08-29 00:00:00

abstract：BACKGROUND:Endocrine mechanisms governing canine reproductive function remain still obscure. Progesterone (P4) of luteal origin is required for maintenance of pregnancy. Corpora lutea (CL) are gonadotrop-independent during the first third of dioestrus; afterwards prolactin (PRL) is the primary luteotropic factor. Inter...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Kowalewski MP,Michel E,Gram A,Boos A,Guscetti F,Hoffmann B,Aslan S,Reichler I

更新日期：2011-08-03 00:00:00

abstract：:Establishment and maintenance of pregnancy in the pig involves intricate communication between the developing conceptuses and the maternal endometrium. This process occurs during trophoblast elongation which is spaciotemporally associated with conceptus synthesis and release of IL1B concomitant with pregnancy-specific...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Ross JW,Ashworth MD,Mathew D,Reagan P,Ritchey JW,Hayashi K,Spencer TE,Lucy M,Geisert RD

更新日期：2010-04-28 00:00:00

abstract：:Cloning mammals by nuclear transfer is a powerful technique that is quickly advancing the development of genetically defined animal models. However, the overall efficiency of nuclear transfer is still very low and several hurdles remain before the power of this technique will be fully harnessed. Among these hurdles in...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Li X,Li Z,Jouneau A,Zhou Q,Renard JP

更新日期：2003-11-07 00:00:00

abstract：BACKGROUND:The purpose of this study was to test the hypothesis that menstruation is associated with a higher concentration of endometrial cells in peritoneal fluid(PF) and with increased white and red blood cell concentration in PF when compared to nonmenstrual phases of the cycle. METHODS:PF was obtained at laparosc...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Bokor A,Debrock S,Drijkoningen M,Goossens W,Fülöp V,D'Hooghe T

更新日期：2009-10-30 00:00:00

abstract：BACKGROUND:Adequate maternal nutrition during gestation is requisite for fetal nutrition and development. While a large group of epidemiological studies indicate poor fetal nutrition increases heart disease risk and mortality in later life, little work has focused on the effects of impaired maternal nutrition on fetal ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gilbert JS,Lang AL,Nijland MJ

更新日期：2005-07-14 00:00:00

abstract：:Although much is known about the reproductive biology of pond-breeding frogs, there is comparatively little information about terrestrial-breeding anurans, a highly successful and diverse group. This study investigates the activation and in vitro fertilization of eggs of the Puerto Rican coqui frog obtained by hormona...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Toro E,Michael SF

更新日期：2004-08-05 00:00:00

abstract：BACKGROUND:Low functional ovarian reserve (LFOR) has been associated with hypoandrogenemia and increased embryo aneuploidy, while androgen supplementation has been reported to improve aneuploidy rates. We, therefore, assessed whether in infertile women undergoing in vitro fertilization (IVF) androgen concentrations are...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gleicher N,McCulloh DH,Kushnir VA,Ganguly N,Barad DH,Goldman KN,Kushnir MM,Albertini DF,Grifo JA

更新日期：2015-05-06 00:00:00

abstract：BACKGROUND:Endometriosis is an estrogen dependent, inflammatory disorder occurring in 5-10% of reproductive-aged women. Women with endometriosis have a lower body mass index (BMI) and decreased body fat compared to those without the disease, yet few studies have focused on the metabolic abnormalities in adipose tissue ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zolbin MM,Mamillapalli R,Nematian SE,Goetz L,Taylor HS

更新日期：2019-04-15 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the effects of vitrification on morpho-functional parameters (blastomere/chromatin integrity and bioenergy/oxidative potential) of mouse preimplantation embryos. METHODS:In vivo produced mouse (4/16-cell, morulae and blastocyst-stage) embryos were randomly divided into ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Martino NA,Dell'aquila ME,Cardone RA,Somoskoi B,Lacalandra GM,Cseh S

更新日期：2013-04-03 00:00:00

abstract：BACKGROUND:Coordinated differentiation of the endometrial compartments in the second half of the menstrual cycle is a prerequisite for the establishment of pregnancy. Endometrial stromal cells (ESC) decidualize under the influence of ovarian progesterone to accommodate implantation of the blastocyst and support establi...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Samalecos A,Reimann K,Wittmann S,Schulte HM,Brosens JJ,Bamberger AM,Gellersen B

更新日期：2009-07-20 00:00:00

abstract：BACKGROUND:Through this prospective study, we aimed to explore the change of molecular modification after the transient scrotal hyperthermia on human sperm. METHODS:Ten healthy subjects selected with strict screening criteria underwent testicular warming in a 43 °C water bath for 30 min a day for 10 consecutive days. ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Wu YQ,Rao M,Hu SF,Ke DD,Zhu CH,Xia W

更新日期：2020-08-12 00:00:00

abstract：BACKGROUND:Male factor infertility is quite common as 30-50% of infertility cases are due to sperm defects. The high sperm DNA fragmentation is one of the causes of male factor infertility. Many factors cause sperm DNA fragmentation and could be testicular or post-testicular. The purpose of this study was to assess rel...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Al Omrani B,Al Eisa N,Javed M,Al Ghedan M,Al Matrafi H,Al Sufyan H

更新日期：2018-05-19 00:00:00

abstract：:We have investigated the effects of indomethacin (IM), a non-steroidal anti-inflammatory drug, and the role of prostaglandins on the accumulation of leukocytes in the rat ovary during the periovulatory period. Adult cycling rats were injected sc with 1 mg of IM in olive oil or vehicle on the morning of proestrus. Some...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gaytán F,Morales C,Bellido C,Tarradas E,Sánchez-Criado JE

更新日期：2003-02-14 00:00:00

abstract：BACKGROUND:In early pregnancy, increased plasma levels of the endocannabinoid anandamide (AEA) are associated with miscarriage through mechanisms that might affect the developing placenta or maternal decidua. METHODS:In this study, we compare AEA levels in failed and viable pregnancies with the levels of the trophobla...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Taylor AH,Finney M,Lam PM,Konje JC

更新日期：2011-11-29 00:00:00

abstract：BACKGROUND:The full maturational capability of mammalian oocytes is accompanied by nuclear and cytoplasmic modifications, which are associated with proliferation and differentiation of surrounding cumulus cells. These events are regulated on molecular level by the expression of target genes involved in signal transduct...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Budna J,Rybska M,Ciesiółka S,Bryja A,Borys S,Kranc W,Wojtanowicz-Markiewicz K,Jeseta M,Sumelka E,Bukowska D,Antosik P,Brüssow KP,Bruska M,Nowicki M,Zabel M,Kempisty B

更新日期：2017-06-02 00:00:00

abstract：BACKGROUND:Wolfram Syndrome (WS) is an autosomal recessive disorder characterised by non-autoimmune diabetes mellitus, optic atrophy, cranial diabetes insipidus and sensorineural deafness. Some reports have described hypogonadism in male WS patients. The aim of our study was to find out whether Wfs1 deficient (Wfs1KO) ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Noormets K,Kõks S,Kavak A,Arend A,Aunapuu M,Keldrimaa A,Vasar E,Tillmann V

更新日期：2009-08-10 00:00:00

abstract：BACKGROUND:With infertility populations rapidly aging, treatments improving pregnancy chances assume increasing clinical importance. Dehydroepiandrosterone (DHEA) has been reported to improve pregnancy rates and lower miscarriage rates in women with diminished ovarian function. This study was planned to evaluate whethe...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Tartagni M,Cicinelli MV,Baldini D,Tartagni MV,Alrasheed H,DeSalvia MA,Loverro G,Montagnani M

更新日期：2015-03-09 00:00:00

abstract：BACKGROUND:During the estrous cycle, the rat uterine endometrium undergoes many changes such as cell proliferation and apoptosis. If implantation occurs, stromal cells differentiate into decidual cells and near the end of pregnancy, a second wave of apoptosis occurs. This process called decidual regression, is tightly ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Caron PL,Fréchette-Frigon G,Shooner C,Leblanc V,Asselin E

更新日期：2009-08-05 00:00:00