Red blood cell glutathione peroxidase activity in female nulligravid and pregnant rats.

Abstract:

BACKGROUND:The alterations of the glutathione peroxidase enzyme complex system occur in physiological conditions such as aging and oxidative stress consequent to strenuous exercise. METHODS:Authors optimize the spectrophotometric method to measure glutathione peroxidase activity in rat red blood cell membranes. RESULTS:The optimization, when applied to age paired rats, both nulligravid and pregnant, shows that pregnancy induces, at seventeen d of pregnancy, an increase of both reactive oxygen substance concentration in red blood cells and membrane glutathione peroxidase activity. CONCLUSION:The glutathione peroxidase increase in erythrocyte membranes is induced by systemic oxidative stress long lasting rat pregnancy.

journal_name

Reprod Biol Endocrinol

authors

Gallo G,Martino G

doi

10.1186/1477-7827-7-7

subject

Has Abstract

pub_date

2009-01-26 00:00:00

pages

7

issn

1477-7827

pii

1477-7827-7-7

journal_volume

7

pub_type

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