CAPN 7 promotes the migration and invasion of human endometrial stromal cell by regulating matrix metalloproteinase 2 activity.

abstract：BACKGROUND:Adrenomedullin (ADM), a novel vasorelaxant peptide, was found in human/rat ovaries. The present study investigated the interaction of ADM and endothelin-1 (ET-1) in follicles and newly formed corpora lutea (CL) and the actions of ADM on progesterone production in CL during pregnancy. METHODS:The peptide and...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Li L,O WS,Tang F

更新日期：2011-08-09 00:00:00

abstract：BACKGROUND:Polycystic Ovary Syndrome (PCOS) is the most common gynecological endocrinopathy in women of reproductive age. Despite its heavy burden on female reproduction and general health, there is no study regarding PCOS prevalence in Palestine. This study aims to establish prevalence of PCOS among female university ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Musmar S,Afaneh A,Mo'alla H

更新日期：2013-05-20 00:00:00

abstract：BACKGROUND:We demonstrated that E2 conjugated to BSA (E2BSA) induces a rapid membrane-initiated inhibition of LH secretion followed hours later by a slight increase in LH secretion. Whether these actions of E2BSA are restricted to the pituitary gland and whether the membrane-initiated pathway of E2BSA contributes to th...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Arreguin-Arevalo JA,Ashley RL,Wagenmaker ER,Oakley AE,Karsch FJ,Nett TM

更新日期：2010-05-10 00:00:00

abstract：:Gonadotropin-primed immature rats (GPIR) constitute a widely used model for the study of ovulation. Although the equivalence between the ovulatory process in immature and adult rats is generally assumed, the morphological and functional characteristics of ovulation in immature rats have been scarcely considered. We de...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gaytan M,Bellido C,Morales C,Gonzalez-Padilla M,Sanchez-Criado JE,Gaytan F

更新日期：2004-09-03 00:00:00

abstract：BACKGROUND:Hatching is crucial for mammalian embryo implantation, since difficulties during this process can lead to implantation failure, ectopic pregnancy and consequent infertility. Despite years of intensive researches, how internal and external factors affecting embryo hatch are still largely unclear. METHODS:The...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zhan S,Cao S,Du H,Sun Y,Li L,Ding C,Zheng H,Huang J

更新日期：2018-04-21 00:00:00

abstract：:During the follicular phase of the primate menstrual cycle, a single follicle usually matures to the preovulatory stage and releases its oocyte for fertilization and the potential establishment of pregnancy. In assisted reproductive technology procedures, it is desirable to override the natural process of follicle sel...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zeleznik AJ

更新日期：2004-06-16 00:00:00

abstract：BACKGROUND:ATF6α, one of the sensor proteins in the stress signaling pathway of the endoplasmic reticulum, is located in the membrane of the endoplasmic reticulum. To date, the physiological function of ATF6α in the process of embryo implantation has not been reported. METHODS:In this study, the expression pattern of ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Xiong Y,Li W,Lin P,Wang L,Wang N,Chen F,Li X,Wang A,Jin Y

更新日期：2016-10-07 00:00:00

abstract：BACKGROUND:Antagonists of growth hormone-releasing hormone (GHRH) are being developed for the treatment of various human cancers. METHODS:MTT assay was used to test the proliferation of SKOV3 and CaOV3. The splice variant expression of GHRH receptors was examined by RT-PCR. The expression of protein in signal pathway ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Guo J,Schally AV,Zarandi M,Varga J,Leung PC

更新日期：2010-05-28 00:00:00

abstract：BACKGROUND:Methadone is the therapeutic agent of choice for the treatment of opiate addiction in pregnancy. The co-consumption (heroin, cocaine) which may influence the effects of methadone is frequent. Therefore, the impact of cocaine and heroin on the placental transfer of methadone and the placental tissue was inves...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Malek A,Obrist C,Wenzinger S,von Mandach U

更新日期：2009-06-11 00:00:00

abstract：BACKGROUND:Despite being born with a significant number of primordial cells which representing the ancestor cells of the germ-line, women experience a depletion of ovarian reserve and sub-fertility mid-way into their healthy lives. The poor ovarian response is a substantial limiting factor amplified with higher materna...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Khan HL,Bhatti S,Suhail S,Gul R,Awais A,Hamayun H,Enver F,Abbas S,Hassan Z,Nisar R,Sardar S,Asif W

更新日期：2019-02-11 00:00:00

abstract：BACKGROUND:TGF-beta is a multifunctional growth factor involved in regulating a variety of cellular activities. Unlike mammals, the function of TGF-beta in the reproduction of lower vertebrates, such as fish, is not clear. Recently, we showed that TGF-beta1 inhibits gonadotropin- and 17alpha, 20beta-dihydroxyprogestero...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Kohli G,Clelland E,Peng C

更新日期：2005-09-30 00:00:00

abstract：BACKGROUND:Progesterone plays an important role in the proliferation and differentiation of human endometrial cells (hECs). Large-dose treatment with progesterone has been used for treatment of endometrial proliferative disorders. However, the mechanisms behind remain unknown. METHODS:To investigate the role of cyclin...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Tang L,Zhang Y,Pan H,Luo Q,Zhu XM,Dong MY,Leung PC,Sheng JZ,Huang HF

更新日期：2009-12-07 00:00:00

abstract：BACKGROUND:Endocrine mechanisms governing canine reproductive function remain still obscure. Progesterone (P4) of luteal origin is required for maintenance of pregnancy. Corpora lutea (CL) are gonadotrop-independent during the first third of dioestrus; afterwards prolactin (PRL) is the primary luteotropic factor. Inter...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Kowalewski MP,Michel E,Gram A,Boos A,Guscetti F,Hoffmann B,Aslan S,Reichler I

更新日期：2011-08-03 00:00:00

abstract：BACKGROUND:Endometriosis is an estrogen dependent, inflammatory disorder occurring in 5-10% of reproductive-aged women. Women with endometriosis have a lower body mass index (BMI) and decreased body fat compared to those without the disease, yet few studies have focused on the metabolic abnormalities in adipose tissue ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zolbin MM,Mamillapalli R,Nematian SE,Goetz L,Taylor HS

更新日期：2019-04-15 00:00:00

abstract：BACKGROUND:Brain-derived ectonucleoside triphosphate diphosphohydrolases (NTPDases) have been known as plasma membrane-incorporated enzymes with their ATP-hydrolyzing domain outside of the cell. As such, these enzymes are thought to regulate purinergic intercellular signaling by hydrolyzing ATP to ADP-AMP, thus regulat...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zsarnovszky A,Bartha T,Frenyo LV,Diano S

更新日期：2009-06-16 00:00:00

abstract：BACKGROUND:Claudin-4 (CLDN4) is one of several proteins that act as molecular mediators of embryo implantation. Recently, we examined immunolabeling of leukemia inhibitory factor (LIF) in the endometrial tissue of 52 IVF patients, and found that LIF staining intensity was strongly correlated with successful pregnancy i...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Serafini PC,Silva ID,Smith GD,Motta EL,Rocha AM,Baracat EC

更新日期：2009-04-19 00:00:00

abstract：BACKGROUND:Meta-analysis revealed that embryo placement 20 mm from the fundal endometrial surface resulted in higher pregnancy rate, ongoing pregnancy rate, and live birth rate compared with placement 10 mm from the fundal endometrial surface. Pregnancy and implantation rates according to relative position were higher ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Kwon H,Choi DH,Kim EK

更新日期：2015-07-29 00:00:00

abstract：:Sexual health is strictly related with general health in both genders. In presence of a sexual dysfunction, the expert in sexual medicine aims to discover the specific weight of the physical and psychological factors can cause or con-cause the sexual problem. At the same time, a sexual dysfunction can represent a mark...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Mollaioli D,Ciocca G,Limoncin E,Di Sante S,Gravina GL,Carosa E,Lenzi A,Jannini EAF

更新日期：2020-02-17 00:00:00

abstract：:The present study evaluates the participation of the vagus nerve in pre-pubertal rats with unilateral ovariectomy on puberty onset, and on progesterone, testosterone and estradiol serum levels, and the compensatory responses of the ovary. Unilateral vagotomy did not modify the onset of puberty in unilaterally ovariect...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Morales L,Ricardo B,Bolaños A,Chavira R,Domínguez R

更新日期：2007-06-13 00:00:00

abstract：BACKGROUND:To evaluate the association between leukocytes (polymorphonuclear granulocytes -PMNL) and semen parameters at different leukocyte concentrations. METHODS:This was a retrospective clinical study at a university hospital andrology clinic. Semen samples from infertile men were analyzed for sperm morphology and...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Lackner JE,Agarwal A,Mahfouz R,du Plessis SS,Schatzl G

更新日期：2010-02-05 00:00:00

abstract：BACKGROUND:Several medical conditions can affect and disrupt human sexuality. The alteration of sexuality in these medical conditions often hinder effective communication and empathy between the patients and their sexual partners because of cultural attitudes, social norms and negative feelings such as anxiety and guil...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Amidu N,Owiredu WK,Woode E,Appiah R,Quaye L,Gyasi-Sarpong CK

更新日期：2010-10-13 00:00:00

abstract：BACKGROUND:Limitations in our current knowledge of normative physiologic changes in thyroid function during the periconception window narrow our ability to establish an optimal approach to screening and diagnosis of thyroid disease in pregnant women. The objective of this study was to characterize changes in thyroid fu...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Balthazar U,Steiner AZ

更新日期：2012-03-21 00:00:00

abstract：BACKGROUND:Several kinds of anti-oxidants have drawn a lot of intention for their benefits on vascular protection. In addition, it has been demonstrated that exercise training could improve endothelial function by up-regulating endothelial nitric oxide synthase (eNOS) protein. Therefore, the present study aims to inves...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Eksakulkla S,Suksom D,Siriviriyakul P,Patumraj S

更新日期：2009-09-07 00:00:00

abstract：BACKGROUND:Stereology is an established method to extrapolate three-dimensional quantities from two-dimensional images. It was applied to placentation in the mouse, but not yet for other rodents. Herein, we provide the first study on quantitative placental development in a sigmodontine rodent species with relatively si...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Favaron PO,Mess AM,de Oliveira MF,Gabory A,Miglino MA,Chavatte-Palmer P,Tarrade A

更新日期：2013-02-21 00:00:00

abstract：BACKGROUND:To examine the effects of IVF, ICSI and FET, as well as in vitro culture, on the safety of offspring, this study was conducted from the perspective of genetic imprinting to investigate whether assisted reproductive technology would influence the parental and maternal imprinting genes. METHODS:Eighteen foetu...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Ji M,Wang X,Wu W,Guan Y,Liu J,Wang J,Liu W,Shen C

更新日期：2018-07-05 00:00:00

abstract：:Human spermatozoa generate low levels of reactive oxygen species in order to stimulate key events, such as tyrosine phosphorylation, associated with sperm capacitation. However, if the generation of these potentially pernicious oxygen metabolites becomes elevated for any reason, spermatozoa possess a limited capacity ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Baker MA,Aitken RJ

更新日期：2005-11-29 00:00:00

abstract：BACKGROUND:To assess the amount of variability in ovarian follicular growth rate and maximum follicular diameter related to different centers, women and cycles of the same women in a multicenter observational study of follicular growth. METHODS:Secondary analysis of a prospective cohort study from eight centers in Eur...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Mikolajczyk RT,Stanford JB,Ecochard R

更新日期：2008-12-10 00:00:00

abstract：BACKGROUND:Secreted protein of Ly-6 domain 1 (SOLD1), a secretory-type member of the Ly-6 superfamily, is expressed in both fetal and maternal tissues throughout gestation. SOLD1 mRNA is expressed in the endometrium and in trophoblast mononucleate and binucleate cells, suggesting it plays an important role not only in ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Awad M,Koshi K,Kizaki K,Takahashi T,Hashizume K

更新日期：2014-06-21 00:00:00

abstract：BACKGROUND:Embryo selection has been an integral feature of in vitro fertilization (IVF) almost since its inception. Since the advent of extended blastocyst stage embryo culture, and especially with increasing popularity of elective single embryo transfer (eSET), the concept of embryo selection has increasingly become ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gleicher N,Kushnir VA,Barad DH

更新日期：2015-01-11 00:00:00

abstract：BACKGROUND:In animals, low levels of vitamin D are associated with estrus cycle disturbances, but there are virtually no human data. We examined the association of 25-hydroxyvitamin D (25(OH)D) (a biomarker for vitamin D status) with menstrual cycle characteristics. METHODS:Women aged 35-44 were randomly selected from...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Jukic AM,Steiner AZ,Baird DD

更新日期：2015-03-11 00:00:00