Dynamic investigation for evaluation of calcium metabolism and parathyroid function.

Abstract:

:Differently from other metabolic conditions, most of calcium metabolism disorders are diagnosed through simple detection of both serum and urinary excretion (24-h urine collection), levels of calcium, total and ionized form, and phosphate, and of calciotropic hormone serum levels, such as calcitonin, PTH and vitamin D metabolites. For the diagnosis and clinical monitoring of some metabolic bone diseases, such as osteoporosis and Paget's disease, the assessment of bone turnover is offering a useful tool for the evaluation of the therapeutic response in affected individuals. Markers of bone formation are represented by bone alkaline phosphatase and osteocalcin, while principal bone resorption markers are represented by pyridinoline, deoxypyridinoline and crosslinks of collagen N-telopeptide, both in the 24-h and fasting second morning urine collection. Only in selected conditions, here briefly reviewed, dynamic tests can offer an interpretation on the pathogenetic events causing a disorder of calcium metabolism.

journal_name

J Endocrinol Invest

authors

Cioppi F,Falchetti A,Masi L,Brandi ML

keywords:

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

83-91

issue

7 Suppl

eissn

0391-4097

issn

1720-8386

journal_volume

26

pub_type

杂志文章,评审
  • Portal, hepatic and peripheral insulin immunoreactive substances before and after removal of an insulinoma.

    abstract::Plasma insulin immunoreactivity (IRI) results from high molecular weight substances with insulin immunoreactivity (HWIRI), proinsulin (PI) and insulin (I). Their respective concentrations and percentages of IRI were determined preoperatively in the hepatic and peripheral circulations and after surgery in the latter tw...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03350520

    authors: Villaume C,Beck B,Pointel JP,Drouin P,Debry G

    更新日期:1982-09-01 00:00:00

  • Simple radioimmunological assay of anti-alpha-galactosyl antibody (anti-Gal): application to autoimmune thyroid diseases and thyroid-associated ophthalmopathy.

    abstract::Two radioimmunological techniques for the measurement of anti-alpha-galactosyl (anti-Gal) antibodies were developed and we demonstrated that this antibody is present in the serum of most untreated patients with Graves' disease, thyroid-associated ophthalmopathy (TAO) and autoimmune thyroiditis. Thyrotropin-binding inh...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03349806

    authors: Winand RJ,Winand-Devigne J,Cox C,Caulier C,Meurisse M

    更新日期:1995-11-01 00:00:00

  • Thyroid ultrasonography related to clinical and laboratory findings in patients with silent thyroiditis.

    abstract::We summarized the clinical course of 10 patients with silent thyroiditis and evaluated the clinical usefulness of ultrasonography, in combination with clinical and laboratory findings, for the differentiation from Graves' disease. Serum T3 and T4 were increased in all cases, and the ratio of T3/T4 (ng/micrograms) was ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03348732

    authors: Miyakawa M,Tsushima T,Onoda N,Etoh M,Isozaki O,Arai M,Shizume K,Demura H

    更新日期:1992-04-01 00:00:00

  • Adult subjects with Prader-Willi syndrome show more low-grade systemic inflammation than matched obese subjects.

    abstract:AIM:Adult subjects with Prader-Willi syndrome (PWS) may show several conditions that are associated with an activation of innate immunity such as obesity, deficient GH secretion or hypogonadism. Our aim was to study whether obese adult PWS subjects show an additional low-grade systemic inflammation (LGSI) in relation t...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03345585

    authors: Caixàs A,Giménez-Palop O,Broch M,Vilardell C,Megía A,Simón I,Giménez-Pérez G,Mauricio D,Vendrell J,Richart C,González-Clemente JM

    更新日期:2008-02-01 00:00:00

  • Solubilized TSH-receptor: its usefulness for the radioligand receptor assay for TSH and TSH-displacing antibody.

    abstract::The usefulness of solubilized TSH-receptor for measuring TSH and TSH-displacing antibodies (TDA) in a radioligand receptor assay (RRA) was investigated. Crude thyroid membranes were solubilized with Triton X-100. A soluble protein fraction was isolated by DEAE-Sephadex A-50 ion-exchange chromatography. The binding of ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03350444

    authors: Kotulla P,Schleusener H

    更新日期:1981-04-01 00:00:00

  • Effects of sex steroids on expression of adenylyl cyclase messenger RNA in rat uterus.

    abstract::The aim of our study was to investigate the effects of estradiol (E2) and/or progesterone (P4) bilateral ovariectomized rats on gene expressions of adenylyl cyclases (AC2, AC4, AC6, AC9). Non-pregnant (NP) Wister rats (between post-natal 10 and 12 weeks) and normal pregnant rats (between postnatal 10 and 14 weeks) wer...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347203

    authors: Asano K,Okawa T,Matsuoka I,Suzuki Y,Sato A

    更新日期:2005-04-01 00:00:00

  • Corticotropin-releasing factor and adrenal function in major depression.

    abstract::We investigated ACTH and cortisol responses after ovine CRF injection (1 microgram/kg one bolus) in a group of 11 drug-free patients suffering from major depression. When compared to sex- and age-matched normal controls, our depressed patients showed: Higher ACTH basal values (p less than 0.002); higher cortisol basal...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03350921

    authors: Nerozzi D,Bersani G,Melia E,Magnani A,Antonozzi I,Frajese G

    更新日期:1988-11-01 00:00:00

  • The growth hormone response to hexarelin in patients with Prader-Willi syndrome.

    abstract::Hexarelin (Hex) is a synthetic hexapeptide with potent GH-releasing activity in both animals and men. Aim of this study was to evaluate the GH response to a maximal dose of Hex and GH-releasing hormone (GHRH) in a group of patients with Prader-Willi syndrome (PWS). Seven patients (4 boys and 3 girls, age 2.4-14.2 yr) ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347335

    authors: Cappa M,Raguso G,Palmiotto T,Faedda A,Gurreri F,Neri G,Deghenghi R,Loche S

    更新日期:1998-09-01 00:00:00

  • Growth hormone treatment in non-growth hormone-deficient short children.

    abstract::The unlimited availability of GH obtained by recombinant DNA technology has allowed optimization of treatment in GH-deficient (GHD) children. At the same time it has prompted a number of studies in conditions not characterized by GHD such as Turner syndrome, intrauterine growth retardation, chronic renal failure and o...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:10.1007/BF03345367

    authors: Loche S,Casini MR,Ubertini GM,Cappa M

    更新日期:2005-02-01 00:00:00

  • A study on the hyperinsulinism of late pregnancy.

    abstract::Much research has demonstrated that in late pregnancy glucose administration causes a marked increase of peripheral insulin levels. To ascertain whether this particular increase is due to increased insulin secretion and/or to reduced hepatic insulin removal, we measured blood glucose, plasma C-peptide and plasma insul...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347933

    authors: Piva I,Erle G,Thiella M,Lora L,Strazzabosco M,Sicolo N,Federspil G

    更新日期:1991-11-01 00:00:00

  • Estriol affects prolactin and LH secretion in rats.

    abstract::The effects of estriol on serum prolactin (PRL) and LH levels, on the pituitary response to TRH and LHRH and on the synthesis and release of PRL from the anterior pituitary gland were investigated in female rats. The increase of serum PRL levels after estradiol administration was found to be associated with an increas...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03349902

    authors: Diaz MC,Seilicovich A,Duvilanski BH,Siseles N,Lasaga M,Debeljuk L

    更新日期:1989-01-01 00:00:00

  • Circulating ghrelin levels as function of gender, pubertal status and adiposity in childhood.

    abstract::Ghrelin, a natural GH secretagogue, exerts remarkable endocrine and non-endocrine activities such as orexigenic effect and modulation of the endocrine and metabolic response to variations in energy balance. Ghrelin levels have been reported to be negatively associated to insulin secretion, enhanced in anorexia and red...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03344026

    authors: Bellone S,Rapa A,Vivenza D,Castellino N,Petri A,Bellone J,Me E,Broglio F,Prodam F,Ghigo E,Bona G

    更新日期:2002-05-01 00:00:00

  • Dyshormonogenetic goiter: presence of an inhibitor of normal human thyroid peroxidase.

    abstract::A dialyzable, thermostable inhibitor of normal thyroid peroxidase (TPO), with UV absorption maximum at 250-260 nm, was found in the digitonized, washed particulate fraction of two dyshormonogenetic goiters. No intrinsic TPO iodide-oxidation activity was detectable in either of these goiters, and their TPO iodination a...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03349651

    authors: Rosenthal D,Carvalho-Guimarães DP,Knobel M,Medeiros-Neto GA

    更新日期:1990-12-01 00:00:00

  • Premature pubarche, ovarian hyperandrogenism, hyperinsulinism and the polycystic ovary syndrome: from a complex constellation to a simple sequence of prenatal onset.

    abstract::Adolescent girls with a history of premature pubarche have an increased incidence of functional ovarian hyperandrogenism [a form of polycystic ovary syndrome (PCOS)] at adolescence, which is usually associated with hyperinsulinemia and dyslipemia. The hyperinsulinemia and lipid disturbances can often be detected in th...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:10.1007/BF03350781

    authors: Ibáñez L,de Zegher F,Potau N

    更新日期:1998-10-01 00:00:00

  • Resistance to somatostatin analogs in acromegaly: an evolving concept?

    abstract::The aim of acromegaly treatment is to control the disease by suppressing GH hyperactivity and reducing the size or impeding the growth of the pituitary GH secreting mass. Over recent years, many studies have emphasized the role of SS analogs in the treatment of acromegaly. In fact, SS analogs have been demonstrated to...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:10.1007/BF03349183

    authors: Gola M,Bonadonna S,Mazziotti G,Amato G,Giustina A

    更新日期:2006-01-01 00:00:00

  • Effect of the somatostatin analog D-Trp8,D-Cys14 on glucose insulin, pancreatic glucagon and growth hormone plasma levels in acromegalics and mild diabetics.

    abstract::The effect of the somatostatin analog (GHRIH-A) D-Trp8, D-Cys14 on plasma levels of growth hormone, pancreatic glucagon, insulin and glucose was studied in four acromegalic patients and in four maturity-onset mild diabetics. Acromegalics received a bolus iv injection of 25 microgram of GHRIH-A, followed by a continuou...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03348250

    authors: Trovati M,Massara F,Camanni F,Molinatti GM,Lorenzati R,Pagano GF

    更新日期:1980-04-01 00:00:00

  • Lipid profile and nutritional intake in children and adolescents with Type 1 diabetes improve after a structured dietician training to a Mediterranean-style diet.

    abstract:AIM:To evaluate if nutritional intakes and lipid profile fulfill international guidelines and recommendations before and after a structured dietician training to a Mediterranean- style diet in an Italian pediatric population with Type 1 diabetes. METHODS:A 6-month prospective cohort study. Baseline and after-intervent...

    journal_title:Journal of endocrinological investigation

    pub_type: 临床试验,杂志文章

    doi:10.3275/7755

    authors: Cadario F,Prodam F,Pasqualicchio S,Bellone S,Bonsignori I,Demarchi I,Monzani A,Bona G

    更新日期:2012-02-01 00:00:00

  • Predictors of electrocardiographic abnormalities in type 1 Diabetes: the Wisconsin Epidemiologic Study of Diabetic Retinopathy.

    abstract:PURPOSE:To determine the incidence and determinants of developing abnormalities on the 12-lead electrocardiogram (ECG) in persons with type 1 diabetes. METHODS:We evaluated the distribution of ECG abnormalities and risk factors for developing new abnormalities in 266 (mean age = 44 years ± 9.0; 50 % female) people wit...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-016-0564-z

    authors: O'Neal WT,Lee KE,Soliman EZ,Klein R,Klein BE

    更新日期:2017-03-01 00:00:00

  • Androstenedione, 17 beta-estradiol and progesterone plasma levels in gonadotropins induction of ovulation.

    abstract::A comparison of peripheral patterns of androstenedione (A), 17 beta-estradiol (E2) and progesterone (P) is reported in ten infertile women during HMG-HCG induction of ovulation, in order to assess the site of ovarian secretion of plasma A and the possible influence on conception. Evidence for both the follicular and l...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03351016

    authors: Scirpa P,Mango D,Montemurro A,Battaglia F,Cantafio L

    更新日期:1984-08-01 00:00:00

  • Reversible cerebral ischemia in patients with pheochromocytoma.

    abstract::Cerebral ischemia and symptoms of stroke can occur as a rare manifestation in patients with pheochromocytoma. We describe a 45-year-old woman who was admitted because of a right-sided hemiparesis due to an ischemic lesion in the left hypothalamus. The clinical diagnosis of a pheochromocytoma was proven by highly eleva...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03343544

    authors: Lehmann FS,Weiss P,Ritz R,Harder F,Staub JJ

    更新日期:1999-03-01 00:00:00

  • Sex-dependency of hepatic alcohol metabolizing enzymes.

    abstract::In mature female rats the administration of testosterone led to a striking reduction of hepatic alcohol dehydrogenase activity, whereas the hepatic microsomal ethanol oxidizing system as well as catalase were both increased in activity under these experimental conditions. Conversely, estradiol left the activities of a...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03348330

    authors: Teschke R,Wiese B

    更新日期:1982-07-01 00:00:00

  • Increased prevalence of primary hyperparathyroidism in treated breast cancer.

    abstract:UNLABELLED:Hypercalcemia occurring in patients with advanced breast cancer (BC) is generally due to osteolytic metastases or to the activity of circulating tumor-derived products. In these conditions, the production of endogenous PTH is reduced. The frequency of hypercalcemia due to primary hyperparathyroidism in breas...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03343867

    authors: Fierabracci P,Pinchera A,Miccoli P,Conte PF,Vignali E,Zaccagnini M,Marcocci C,Giani C

    更新日期:2001-05-01 00:00:00

  • Role of serotoninergic receptors in gonadotropin secretion in male rats.

    abstract::Experimental data concerning the role of serotonin (5-HT) in the control of gonadotropins secretion remain controversial: different receptors subtypes should mediate the serotoninergic action. In the present work we analyzed in prepubertal and adult male rats the FSH and LH responses after administration of the follow...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347993

    authors: Pinilla L,Tena-Sempere M,Aguilar E

    更新日期:1997-07-01 00:00:00

  • Meal intake similarly reduces circulating concentrations of octanoyl and total ghrelin in humans.

    abstract:UNLABELLED:ABSTRACT. Several data show that meal intake and nutritional status regulate circulating ghrelin concentrations in humans. Ghrelin mainly circulates in two different forms: octanoyl and des-octanoyl ghrelin. Most circulating ghrelin is des-octanoyl ghrelin which is considered inactive because it lacks endocr...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:

    authors: Lucidi P,Murdolo G,Di Loreto C,Parlanti N,De Cicco A,Ranchelli A,Fatone C,Taglioni C,Fanelli C,Santeusanio F,De Feo P

    更新日期:2004-05-01 00:00:00

  • Subclinical hypothyroidism: the state of the art.

    abstract::Subclinical hypothyroidism (SH) is a common clinical problem, particularly in adulthood and the elderly. Its prevalence is conditioned by several etiological and risk factors. The highest age- and sex-specific rates are in women over 60. SH may be associated with manifestations of mild thyroid failure, which may rever...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:10.1007/BF03345571

    authors: Arrigo T,Wasniewska M,Crisafulli G,Lombardo F,Messina MF,Rulli I,Salzano G,Valenzise M,Zirilli G,De Luca F

    更新日期:2008-01-01 00:00:00

  • Improvement of iodine deficiency after iodine supplementation in schoolchildren of Azerbaijan was accompanied by hypo and hyperthyrotropinemia and increased title of thyroid autoantibodies.

    abstract:OBJECTIVE:In the mountainous areas of Azerbaijan the schoolchildren suffer from severe Iodine Deficiency (ID) with median Urinary iodine excretion (UIE) 36 mcg/l and prevalence of goiter 99% (estimated by US). In a population of 293,000 schoolchildren aged 8-14 y.o. we administered capsules containing 190 mg of iodized...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:

    authors: Markou KB,Georgopoulos NA,Makri M,Vlasopoulou B,Anastasiou E,Vagenakis GA,Kouloubi K,Theodosopoulos N,Lazarou N,Veizis A,Sakellaropoulos G,Vagenakis AG

    更新日期:2003-01-01 00:00:00

  • Pheochromocytoma combined with pre-clinical Cushing's syndrome in the same adrenal gland.

    abstract::Pheochromocytoma (PHEO) occasionally associates with pathological lesions of the adrenal cortex. In most of them, ectopic adrenocorticotropic hormone (ACTH) produced by PHEO resulted in bilateral adrenocortical hyperplasia. The coexistence of PHEO and pre-clinical Cushing's syndrome (PCS) of the same adrenal gland has...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347247

    authors: Erem C,Hacihasanoglu A,Ersöz HO,Reis AK,Calik A,Ukinç K,Koçak M

    更新日期:2005-06-01 00:00:00

  • Gene variants associated to malignant thyroid disease in familial adenomatous polyposis: a novel APC germline mutation.

    abstract:BACKGROUND AND AIM:Familial adenomatous polyposis (FAP) is an autosomal inherited syndrome characterized by hundreds to thousands colorectal adenomatous polyps with oncological transformation lifetime risk of 100%. FAP is mainly associated with mutations in APC (autosomal dominant inheritance) or MUTYH (autosomal reces...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03346656

    authors: Martayan A,Sanchez-Mete L,Baldelli R,Falvo E,Barnabei A,Conti L,Giacomini P,Appetecchia M,Stigliano V

    更新日期:2010-10-01 00:00:00

  • Longitudinal study on goiter prevalence and goitrogen factors in northeastern Sicily.

    abstract::A longitudinal study was carried out in an area of endemic goiter of north-eastern Sicily. Three different surveys (in 1977, 1983 and 1994) evaluated the epidemiological prevalence of goiter in schoolchildren of the endemic area (towns of Bronte, Troina and Maniaci) in comparison to an iodine sufficient control area (...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03349031

    authors: Regalbuto C,Squatrito S,La Rosa GL,Cercabene G,Ippolito A,Tita P,Salamone S,Vigneri R

    更新日期:1996-10-01 00:00:00

  • Impact of age on plasma vaspin concentration in a group of normal Chinese people.

    abstract:PURPOSE:Visceral adipose tissue-derived serine protease inhibitor (vaspin) is an adipocytokine with insulin-sensitizing effects. Accumulating data implied that vaspin represents a compensatory mechanism but it is unknown how vaspin change during ageing. This study was designed to examine the correlation between plasma ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-016-0533-6

    authors: Xu X,Wen J,Lu Y,Ji H,Zhuang J,Su Y,Liu B,Li H,Xu Y

    更新日期:2017-02-01 00:00:00