Simple radioimmunological assay of anti-alpha-galactosyl antibody (anti-Gal): application to autoimmune thyroid diseases and thyroid-associated ophthalmopathy.

abstract：:The IGFs are ubiquitous and have pleoitropic effects. They are critical for normal growth and development, and for normal functioning of adult tissues. A liver-specific gene-deletion knockout of the IGF-I gene resulted in a mouse model with reduced circulating IGF-I levels, that led to insulin resistance due to the se...

journal_title：Journal of endocrinological investigation

authors： Yakar S,Pennisi P,Kim CH,Zhao H,Toyoshima Y,Gavrilova O,LeRoith D

更新日期：2005-01-01 00:00:00

abstract：PURPOSE:Primary hyperparathyroidism has deleterious effects on health and causes nephrolithiasis and osteoporosis. However, it remains unclear whether parathyroidectomy benefits kidney function among patients with primary hyperparathyroidism. METHODS:In this retrospective study, patients with primary hyperparathyroidi...

journal_title：Journal of endocrinological investigation

authors： Liang CC,Yeh HC,Lo YC,Chou CY,Yen TH,Tsai HC,Hsu SP,Kuo CC

更新日期：2020-07-29 00:00:00

abstract：:In normal man 1,25 (OH)2-vitamin D3 [1,25 (OH)2D] increases both basal and TRH-stimulated prolactinemia; this effect is completely reversible by the calcium antagonist nifedipine. Similarly the 1,25 (OH)2D-induced hypercalcemia is totally inhibited by nifedipine. These findings suggest that both biological effects of ...

journal_title：Journal of endocrinological investigation

authors： Verbeelen D,Vanhaelst L,Fuss M,Van Steirteghem AC

更新日期：1985-04-01 00:00:00

abstract：:We studied the effects of high doses of methimazole (MMI) or propylthiouracil (PTU) on thyroid-stimulating antibody (TSAb), antithyroid microsomal (MCHA) and antithyroglobulin (TGHA) levels in Graves' disease and Hashimoto's thyroiditis. Thirty Graves' hyperthyroid patients were treated for 14 +/- 8 months (mean +/- S...

journal_title：Journal of endocrinological investigation

authors： Romaldini JH,Werner MC,Rodrigues HF,Teixeira VL,Werner RS,Farah CS,Bromberg N

更新日期：1986-06-01 00:00:00

abstract：:Cimetidine, an H2 receptor antagonist, is a potent stimulant of PRL secretion in normal women. In the present study, the PRL response to cimetidine was studied in 34 normal pregnant women and their fetuses during labor. Serum maternal PRL levels increased significantly after the acute iv injection of 400 mg cimetidine...

journal_title：Journal of endocrinological investigation

authors： Messinis IE,Tsirkas N,Diamantis K,Vasakos S,Tsolas O,Lolis D

更新日期：1988-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS) are well-recognized complications of obesity. This study was designed to evaluate the role of the UCP1 -3826 A>G polymorphism, adiponectin levels, leptin/adiponectin ratio (L/A), and main biochemical parameters in 102 unrelated se...

journal_title：Journal of endocrinological investigation

authors： Labruna G,Pasanisi F,Nardelli C,Tarantino G,Vitale DF,Bracale R,Finelli C,Genua MP,Contaldo F,Sacchetti L

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:The significance of vitamin D deficiency in the incidence of bone fractures in children has been under investigated. Here, we aimed to associate serum 25-hydroxyvitamin D levels and fractures in Saudi children. MATERIALS AND METHODS:This cross-sectional study was conducted in 1022 Saudi children without fra...

journal_title：Journal of endocrinological investigation

authors： Al-Daghri NM,Aljohani N,Rahman S,Sabico S,Al-Attas OS,Alokail MS,Al-Ajlan A,Chrousos GP

更新日期：2016-10-01 00:00:00

abstract：:Male to female sex reversal results from failure of testis development. Mutations in the SRY gene or in other genes involved in the sexual differentiation pathway are considered to cause XY gonadal dysgenesis. The majority of the mutations in the SRY described so far are located within the SRY coding region, mainly in...

journal_title：Journal of endocrinological investigation

authors： Assumpção JG,Ferraz LF,Benedetti CE,Maciel-Guerra AT,Guerra G Jr,Marques-de-Faria AP,Baptista MT,de Mello MP

更新日期：2005-07-01 00:00:00

abstract：:Measurement of serum Tg using ultrasensitive assays is proposed to replace TSH-stimulated Tg measurement in the follow-up of differentiated thyroid cancer (DTC). Aim of our study was to verify this possibility using two ultrasensitive Tg assays. We selected 215 DTC patients with undetectable (<1 ng/ml) basal serum Tg ...

journal_title：Journal of endocrinological investigation

authors： Castagna MG,Tala Jury HP,Cipri C,Belardini V,Fioravanti C,Pasqui L,Sestini F,Theodoropoulou A,Pacini F

更新日期：2011-09-01 00:00:00

abstract：:Endothelins (ETs) are potent vasoconstrictive peptides released from the endothelium and other tissues, which act on target cells by receptorial calcium-mediated mechanisms. ET-1 levels are increased in diabetes, and observations suggest the involvement of ETs in the pathogenesis of diabetic angiopathy. However, it is...

journal_title：Journal of endocrinological investigation

authors： De Carlo E,Milanesi A,Martini C,Maffei P,Sicolo N,Scandellari C

更新日期：2000-04-01 00:00:00

abstract：:In a 12-yr-old boy growth arrest occurred after severe head trauma. Evaluation of pituitary endocrine function revealed isolated growth hormone (GH) deficiency. Lack of GH response to GH-releasing factor indicated that the responsible lesion was most likely to be localized in the pituitary gland. GH substitution resul...

journal_title：Journal of endocrinological investigation

authors： Eichler I,Frisch H,Eichler HG,Soukop W

更新日期：1988-06-01 00:00:00

abstract：:We report the case of a 17-year-old girl presenting short stature (height 149 cm, below the 3rd percentile), obesity (weight 83.5 kg, body mass index 37 kg/m2) and secondary amenorrhea, in whom endocrinological evaluation disclosed an absolute lack of GH responsiveness to both suprapituitary challenges and repetitive ...

journal_title：Journal of endocrinological investigation

authors： Scacchi M,Alé G,Silvestri P,Cavagnini F

更新日期：1995-05-01 00:00:00

abstract：PURPOSE:Cold exposure activates the hypothalamus-pituitary-thyroid (HPT) axis, response blunted by previous acute stress or corticosterone administration. Chronic stressors can decrease serum T3 concentration, and thyrotropin-releasing hormone (Trh) expression in the paraventricular nucleus (PVN), but impact on the res...

journal_title：Journal of endocrinological investigation

authors： Castillo-Campos A,Gutiérrez-Mata A,Charli JL,Joseph-Bravo P

更新日期：2020-07-30 00:00:00

abstract：PURPOSE:Spinal cord injury (SCI) affects sexual health of both male and female, but little attention has been given to sexuality of SCI women. Similar to penile erection, vaginal lubrication represents a neurovascular event and then both denervation and vascular damage might contribute to its impairment. Nevertheless, ...

journal_title：Journal of endocrinological investigation

authors： D'Andrea S,Castellini C,Paladino V,Totaro M,Felzani G,Francavilla S,Francavilla F,Barbonetti A

更新日期：2020-07-01 00:00:00

abstract：:In 1992 a significant relationship between bone turnover and the vitamin D receptor (VDR) genotype was reported in Australian subjects of UK-Irish decent. Since then, several groups have investigated the relationship between VDR and other bone-related genotypes, bone mass and bone turnover in several populations. Howe...

journal_title：Journal of endocrinological investigation

authors： Sheehan D,Bennett T,Cashman KD

更新日期：2001-04-01 00:00:00

abstract：PURPOSE:The review focused on the role that media reporting plays in the level of public awareness about osteoporosis and its influence on osteoporosis treatment decisions. METHODS:We reviewed the literature on the role of media on three main aspects influencing patient adherence to osteoporosis treatment: the awarene...

journal_title：Journal of endocrinological investigation

authors： Cipriani C,Pepe J,Minisola S,Lewiecki EM

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:Polycystic ovary syndrome (PCOS) was associated with a number of polymorphisms of genes involved in insulin signaling. So far, they have been studied separately. The aim of this study was to verify the impact of the coexistence of two polymorphisms of insulin signaling. METHODS:One hundred consecutive PCOS wom...

journal_title：Journal of endocrinological investigation

authors： Pappalardo MA,Vita R,Di Bari F,Le Donne M,Trimarchi F,Benvenga S

更新日期：2017-04-01 00:00:00

abstract：:The present experiments were undertaken to study the effect of complete food removal on body weight, pituitary growth hormone (GH), plasma GH and glucose concentration in male and female Wistar rats. Plasma and pituitary GH levels were measured by means of a specific radioimmunoassay. Plasma glucose concentration decr...

journal_title：Journal of endocrinological investigation

authors： Gonzalez C,Jolin T

更新日期：1981-01-01 00:00:00

abstract：:To investigate whether chronic endogenous hypercalcemia influences TSH and/or PRL release from pituitary thyrotrophs and lactotrophs in man, 10 patients with endogenous hypercalcemia, due either to cancer or to primary hyperparathyroidism, were injected with 25 micrograms TRH iv. The TSH and PRL responses were compare...

journal_title：Journal of endocrinological investigation

authors： Röjdmark S,Edström E,Nordlund M

更新日期：1984-12-01 00:00:00

abstract：:Human gonadotropins are widely used for induction of ovulation in the treatment of anovulatory infertility and for induction of multiple follicular development (MFD) in in vitro fertilization (IVF), gamete intrafallopian transfer (GIFT), and artificial insemination with husband's semen (AIH) programs. Reported is a pa...

journal_title：Journal of endocrinological investigation

authors： Mais V,Melis GB,Antinori D,Paoletti AM,Strigini F,Guerriero S,de Ruggiero A,Fioretti P

更新日期：1990-10-01 00:00:00

abstract：:A longitudinal study was carried out in an area of endemic goiter of north-eastern Sicily. Three different surveys (in 1977, 1983 and 1994) evaluated the epidemiological prevalence of goiter in schoolchildren of the endemic area (towns of Bronte, Troina and Maniaci) in comparison to an iodine sufficient control area (...

journal_title：Journal of endocrinological investigation

authors： Regalbuto C,Squatrito S,La Rosa GL,Cercabene G,Ippolito A,Tita P,Salamone S,Vigneri R

更新日期：1996-10-01 00:00:00

abstract：:An abnormal regulation of the hypothalamic-pituitary-adrenal (HPA) axis is associated with risk factors for cardiovascular disease and Type 2 diabetes mellitus. The objective of this study was to examine if morning saliva cortisols show similar associations. Twenty-eight men, all 53 yr of age, delivered during an ordi...

journal_title：Journal of endocrinological investigation

authors： Wallerius S,Rosmond R,Ljung T,Holm G,Björntorp P

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors determine a wide reduction of LDL cholesterol, greater than other lipid-lowering agents. The present meta-analysis is aimed at the assessment of PCSK9 inhibitors effect on LDL Cholesterol, cardiovascular morbidity and all-cause mortali...

journal_title：Journal of endocrinological investigation

authors： Dicembrini I,Giannini S,Ragghianti B,Mannucci E,Monami M

更新日期：2019-09-01 00:00:00

abstract：:Established methods for definitive ablation of autonomous thyroid nodules are surgery and radioiodine. Since it has been demonstrated that percutaneous ethanol injection can inactivate parathyroid adenomas and small hepatocellular carcinomas, we started a trial of this treatment in patients with autonomous thyroid nod...

journal_title：Journal of endocrinological investigation

authors： Paracchi A,Ferrari C,Livraghi T,Reschini E,Macchi RM,Bergonzi M,Raineri P

更新日期：1992-05-01 00:00:00

abstract：:Whole-body vibration is reported to increase muscle performance, bone mineral density and stimulate the secretion of lipolytic and protein anabolic hormones, such as GH and testosterone, that might be used for the treatment of obesity. To date, as no controlled trial has examined the effects of vibration exercise on t...

journal_title：Journal of endocrinological investigation

authors： Di Loreto C,Ranchelli A,Lucidi P,Murdolo G,Parlanti N,De Cicco A,Tsarpela O,Annino G,Bosco C,Santeusanio F,Bolli GB,De Feo P

更新日期：2004-04-01 00:00:00

abstract：:According to recent studies showing the presence of estrogens receptors (ERs) in the human female lower urinary tract, we performed ER and progesterone receptor (PR) assays in fresh frozen and paraffin embedded biopsies taken from the urinary bladder. Fourteen females undergoing endoscopy during staging for gynecologi...

journal_title：Journal of endocrinological investigation

authors： Pacchioni D,Revelli A,Casetta G,Cassoni P,Piana P,Tizzani A,Bussolati G,Massobrio M

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Thyroid-stimulating hormone (TSH) plays an important role in the regulation of lipid metabolism. However, little is known about the role that exosomes play in the process of TSH-induced lipotoxicity in non-alcoholic fatty liver disease (NAFLD). As a preliminary step, the present study set out to investigate ...

journal_title：Journal of endocrinological investigation

authors： Ma S,Shao S,Yang C,Yao Z,Gao L,Chen W

更新日期：2020-09-01 00:00:00

abstract：:A study of the effects of salmon calcitonin (sCT) infusion on blood sugar and serum insulin levels under basal conditions and after intravenous glucose load in normal subjects is reported. Under basal conditions, a 30 min infusion of sCT at approximately a rate of 1 U/min produced a highly significant increase in the ...

journal_title：Journal of endocrinological investigation

authors： Petralito A,Lunetta M,Liuzzo A,Fiore CE,Heynen G

更新日期：1979-04-01 00:00:00

abstract：:Diagnosis of endogenous hyperinsulinism caused by insulinoma is based on confirmation of hypoglycemia during the symptoms associated to elevated insulin levels. Patients with insulinoma may demonstrate an excessive insulin response and subsequent hypoglycemia after 1 mg of glucagon iv injection. Glucagon test was perf...

journal_title：Journal of endocrinological investigation

authors： Felício JS,Martins CL,Mileo KB,Semer M,Kalinin L,Nery M,Machado MC,Liberman B

更新日期：2012-06-01 00:00:00

abstract：:Osteoporosis is a multifactorial chronic disease that may become even more prevalent and more of a public health problem in the decades to come. Recent research has indicated that a number of macro- and micronutrients are involved in the development of bone health. In the past decade it became evident that vitamin K p...

journal_title：Journal of endocrinological investigation

authors： Francucci CM,Rilli S,Fiscaletti P,Boscaro M

更新日期：2007-01-01 00:00:00