High mortality by natural and unnatural causes: a 10 year follow up study of patients admitted to a poisoning treatment centre after suicide attempts.

abstract：OBJECTIVE:To independently evaluate the impact of the second phase of the Health Foundation's Safer Patients Initiative (SPI2) on a range of patient safety measures. Design A controlled before and after design. Five substudies: survey of staff attitudes; review of case notes from high risk (respiratory) patients in med...

journal_title：BMJ (Clinical research ed.)

authors： Benning A,Dixon-Woods M,Nwulu U,Ghaleb M,Dawson J,Barber N,Franklin BD,Girling A,Hemming K,Carmalt M,Rudge G,Naicker T,Kotecha A,Derrington MC,Lilford R

更新日期：2011-02-03 00:00:00

abstract：OBJECTIVE:To determine whether inhaled salmeterol, a new long acting inhaled beta adrenergic agonist, reduces nocturnal bronchoconstriction and improves sleep quality in patients with nocturnal asthma. DESIGN:Randomised, double blind, placebo controlled crossover study. SETTING:Hospital outpatient clinics in Edinburg...

journal_title：BMJ (Clinical research ed.)

authors： Fitzpatrick MF,Mackay T,Driver H,Douglas NJ

更新日期：1990-12-15 00:00:00

abstract：OBJECTIVES:To prospectively assess the diagnostic performance of simple ultrasound rules to predict benignity/malignancy in an adnexal mass and to test the performance of the risk of malignancy index, two logistic regression models, and subjective assessment of ultrasonic findings by an experienced ultrasound examiner ...

journal_title：BMJ (Clinical research ed.)

authors： Timmerman D,Ameye L,Fischerova D,Epstein E,Melis GB,Guerriero S,Van Holsbeke C,Savelli L,Fruscio R,Lissoni AA,Testa AC,Veldman J,Vergote I,Van Huffel S,Bourne T,Valentin L

更新日期：2010-12-14 00:00:00

abstract：OBJECTIVE:Although the Polypill concept (proposed in 2003) is promising in terms of benefits for cardiovascular risk management, the potential costs and adverse effects are its main pitfalls. The objective of this study was to identify a tastier and safer alternative to the Polypill: the Polymeal. METHODS:Data on the ...

journal_title：BMJ (Clinical research ed.)

authors： Franco OH,Bonneux L,de Laet C,Peeters A,Steyerberg EW,Mackenbach JP

更新日期：2004-12-18 00:00:00

abstract：OBJECTIVE:To investigate the impact of coexistent psychiatric morbidity on risk of suicide after a suicide attempt. DESIGN:Cohort study with follow-up for 21-31 years. SETTING:Swedish national register based study. PARTICIPANTS:39 685 people (53% women) admitted to hospital for attempted suicide during 1973-82. MAI...

journal_title：BMJ (Clinical research ed.)

authors： Tidemalm D,Långström N,Lichtenstein P,Runeson B

更新日期：2008-11-18 00:00:00

abstract：:Elderly and disabled people have been led to expect great improvements in the quality of community care after April 1993. The choice to live safely at home is to be offered as an alternative to residential care. The financial and organisational relationships are all intended to support this in practice. The Tomlinson ...

journal_title：BMJ (Clinical research ed.)

authors： Jowell T

更新日期：1992-12-05 00:00:00

abstract：OBJECTIVE:To assess the cost effectiveness of different screening strategies for abdominal aortic aneurysm in men, from the perspective of a national health service. SETTING:Screening units at regional hospitals. PARTICIPANTS:Hypothetical cohort of 65 year old men from the general population. MAIN OUTCOME MEASURES:C...

journal_title：BMJ (Clinical research ed.)

authors： Søgaard R,Laustsen J,Lindholt JS

更新日期：2012-07-05 00:00:00

abstract：OBJECTIVE:To estimate trends between 1972-6 and 1996 in the prevalences of asthma and hay fever in adults. DESIGN:Two epidemiological surveys 20 years apart. Identical questions were asked about asthma, hay fever, and respiratory symptoms at each survey. SETTING:Renfrew and Paisley, two towns in the west of Scotland....

journal_title：BMJ (Clinical research ed.)

authors： Upton MN,McConnachie A,McSharry C,Hart CL,Smith GD,Gillis CR,Watt GC

更新日期：2000-07-08 00:00:00

abstract：OBJECTIVE:To conduct a systematic review and meta-analysis of cohort studies of body mass index (BMI) and the risk of all cause mortality, and to clarify the shape and the nadir of the dose-response curve, and the influence on the results of confounding from smoking, weight loss associated with disease, and preclinical...

journal_title：BMJ (Clinical research ed.)

authors： Aune D,Sen A,Prasad M,Norat T,Janszky I,Tonstad S,Romundstad P,Vatten LJ

更新日期：2016-05-04 00:00:00

abstract：OBJECTIVE:To examine how the relaxation of the one child policy and policies to reduce caesarean section rates might have affected trends over time in caesarean section rates and perinatal and pregnancy related mortality in China. DESIGN:Observational study. SETTING:China's National Maternal Near Miss Surveillance Sy...

journal_title：BMJ (Clinical research ed.)

authors： Liang J,Mu Y,Li X,Tang W,Wang Y,Liu Z,Huang X,Scherpbier RW,Guo S,Li M,Dai L,Deng K,Deng C,Li Q,Kang L,Zhu J,Ronsmans C

更新日期：2018-03-05 00:00:00

abstract：OBJECTIVE:To systematically review measures of data quality in electronic patient records (EPRs) in primary care. DESIGN:Systematic review of English language publications, 1980-2001. DATA SOURCES:Bibliographic searches of medical databases, specialist medical informatics databases, conference proceedings, and instit...

journal_title：BMJ (Clinical research ed.)

authors： Thiru K,Hassey A,Sullivan F

更新日期：2003-05-17 00:00:00

abstract：OBJECTIVE:To determine if the macrolide clarithromycin affects mortality and cardiovascular morbidity in patients with stable coronary heart disease. DESIGN:Centrally randomised multicentre trial. All parties at all stages were blinded. Analyses were by intention to treat. SETTING:Five Copenhagen University cardiolog...

journal_title：BMJ (Clinical research ed.)

authors： Jespersen CM,Als-Nielsen B,Damgaard M,Hansen JF,Hansen S,Helø OH,Hildebrandt P,Hilden J,Jensen GB,Kastrup J,Kolmos HJ,Kjøller E,Lind I,Nielsen H,Petersen L,Gluud C,CLARICOR Trial Group.

更新日期：2006-01-07 00:00:00

abstract：OBJECTIVE:To determine whether diurnal variation occurs in the onset of stroke. DESIGN:Community based study over four years. SETTING:Oxfordshire, United Kingdom. SUBJECTS:105,000 people, of whom 675 had a first ever stroke. 545 had a cerebral infarction, 66 had primary intracerebral haemorrhage, 33 had subarachnoid...

journal_title：BMJ (Clinical research ed.)

authors： Wroe SJ,Sandercock P,Bamford J,Dennis M,Slattery J,Warlow C

更新日期：1992-01-18 00:00:00

abstract：OBJECTIVES:To assess the experiences of obstetricians in England and Wales of serum screening for Down's syndrome. DESIGN:Postal questionnaire survey. SUBJECTS:Questionnaires were sent to all practising obstetricians in England and Wales with nonacademic appointments who had not participated in an earlier (randomly s...

journal_title：BMJ (Clinical research ed.)

authors： Green JM

更新日期：1994-09-24 00:00:00

abstract：OBJECTIVE:To evaluate whether follow up of patients with inflammatory bowel disease is better through open access than by routine booked appointments. DESIGN:Pragmatic randomised controlled trial. SETTING:Two district general hospitals in Swansea and Neath, Wales. PARTICIPANTS:180 adults (78 with Crohn's disease, 77...

journal_title：BMJ (Clinical research ed.)

authors： Williams JG,Cheung WY,Russell IT,Cohen DR,Longo M,Lervy B

更新日期：2000-02-26 00:00:00

abstract：OBJECTIVE:To assess adjustment practices for primary outcomes of randomized controlled trials and their impact on the results. DESIGN:Meta-epidemiologic study. DATA SOURCES:25 biomedical journals with the highest impact factor according to Journal Citation Reports 2009. STUDY SELECTION:Randomized controlled trials p...

journal_title：BMJ (Clinical research ed.)

authors： Saquib N,Saquib J,Ioannidis JP

更新日期：2013-07-12 00:00:00

abstract：:Prediction models are developed to aid health care providers in estimating the probability or risk that a specific disease or condition is present (diagnostic models) or that a specific event will occur in the future (prognostic models), to inform their decision making. However, the overwhelming evidence shows that th...

journal_title：BMJ (Clinical research ed.)

authors： Collins GS,Reitsma JB,Altman DG,Moons KG

更新日期：2015-01-07 00:00:00

abstract：OBJECTIVE:To estimate the impact of a national primary care pay for performance scheme, the Quality and Outcomes Framework in England, on emergency hospital admissions for ambulatory care sensitive conditions (ACSCs). DESIGN:Controlled longitudinal study. SETTING:English National Health Service between 1998/99 and 20...

journal_title：BMJ (Clinical research ed.)

authors： Harrison MJ,Dusheiko M,Sutton M,Gravelle H,Doran T,Roland M

更新日期：2014-11-11 00:00:00

abstract：OBJECTIVE:To see whether the issue of AIDS has influenced the observed decline in blood donation in Scotland. DESIGN:Two methods: a quantitative survey using personal interviews based on a questionnaire and a qualitative survey based on group discussions. SETTING:Interviews based on the questionnaire were conducted i...

journal_title：BMJ (Clinical research ed.)

authors： MacAskill SG,Hastings GB,McNeill RE,Gillon J

更新日期：1989-04-15 00:00:00

abstract：OBJECTIVE:To investigate the association between several types of soy products and all cause and cause specific mortality. DESIGN:Population based cohort study. SETTING:Japan Public Health Centre-based Prospective Study, which includes 11 public health centre areas in Japan. PARTICIPANTS:92 915 participants (42 750 ...

journal_title：BMJ (Clinical research ed.)

authors： Katagiri R,Sawada N,Goto A,Yamaji T,Iwasaki M,Noda M,Iso H,Tsugane S,Japan Public Health Center-based Prospective Study Group.

更新日期：2020-01-29 00:00:00

abstract：OBJECTIVE:To determine the incidence of cervical cancer after several negative cervical smear tests at different ages. DESIGN:Prospective observational study of incidence of cervical cancer after the third consecutive negative result based on individual level data in a national registry of histopathology and cytopatho...

journal_title：BMJ (Clinical research ed.)

authors： Rebolj M,van Ballegooijen M,Lynge E,Looman C,Essink-Bot ML,Boer R,Habbema D

更新日期：2009-04-24 00:00:00

abstract：OBJECTIVES:To document the extent to which maternity data are collected and how they are recorded, and to identify problems that may affect their availability throughout the NHS. METHODS:Postal survey in September 1997 with structured questionnaires. SETTING:207 NHS trusts with maternity units in England. PARTICIPAN...

journal_title：BMJ (Clinical research ed.)

authors： Kenney N,Macfarlane A

更新日期：1999-09-04 00:00:00

abstract：OBJECTIVES:To determine whether over the counter cough medicines are effective for acute cough in adults. DESIGN:Systematic review of randomised controlled trials. DATA SOURCES:Search of the Cochrane Acute Respiratory Infections Group specialised register, Cochrane Controlled Trials Register, Medline, Embase, and the...

journal_title：BMJ (Clinical research ed.)

authors： Schroeder K,Fahey T

更新日期：2002-02-09 00:00:00

abstract：OBJECTIVE:To examine the associations between neuraxial anaesthesia or general anaesthesia and clinical outcomes, length of hospital stay, and readmission in adults undergoing lower limb revascularisation surgery. DESIGN:Comparative effectiveness study using linked, validated, population based databases. SETTING:Onta...

journal_title：BMJ (Clinical research ed.)

authors： Roberts DJ,Nagpal SK,Kubelik D,Brandys T,Stelfox HT,Lalu MM,Forster AJ,McCartney CJ,McIsaac DI

更新日期：2020-11-25 00:00:00

abstract：OBJECTIVE:To examine doctors' perspectives about their experiences with handheld computers in clinical practice. DESIGN:Qualitative study of eight focus groups consisting of doctors with diverse training and practice patterns. SETTING:Six practice settings across the United States and two additional focus group sessi...

journal_title：BMJ (Clinical research ed.)

authors： McAlearney AS,Schweikhart SB,Medow MA

更新日期：2004-05-15 00:00:00

abstract：:Diabetic ketoacidosis and hyperosmolar hyperglycemic syndrome (HHS) are life threatening complications that occur in patients with diabetes. In addition to timely identification of the precipitating cause, the first step in acute management of these disorders includes aggressive administration of intravenous fluids wi...

journal_title：BMJ (Clinical research ed.)

authors： Karslioglu French E,Donihi AC,Korytkowski MT

更新日期：2019-05-29 00:00:00

abstract：:The "four principles plus scope" approach provides a simple, accessible, and culturally neutral approach to thinking about ethical issues in health care. The approach, developed in the United States, is based on four common, basic prima facie moral commitments--respect for autonomy, beneficence, nonmaleficence, and ju...

journal_title：BMJ (Clinical research ed.)

authors： Gillon R

更新日期：1994-07-16 00:00:00

abstract：:The identification of the gene for cystic fibrosis has led to the possibility of population based screening for carriers of cystic fibrosis to identify couples at risk of having an affected child. Pilot studies have shown that screening is feasible and does not cause untoward anxiety, though the uptake of testing vari...

journal_title：BMJ (Clinical research ed.)

authors： Modell M

更新日期：1993-10-02 00:00:00

abstract：OBJECTIVE:To assess the role of rhinoviruses in elderly people living in the community. DESIGN:Prospective community based surveillance of elderly people, without intervention. Subjects were telephoned weekly to identify symptomatic upper respiratory tract infections. Symptoms and impact of illnesses were monitored, a...

journal_title：BMJ (Clinical research ed.)

authors： Nicholson KG,Kent J,Hammersley V,Cancio E

更新日期：1996-11-02 00:00:00

abstract：:One hundred and two patients returned structured questionnaires sent to clinics for sickle cell disease in the United Kingdom in order to gain greater insight into the patients' perception of painful crises. Most patients who suffer pain crises experience a prodromal stage that should be investigated further to find o...

journal_title：BMJ (Clinical research ed.)

authors： Murray N,May A

更新日期：1988-08-13 00:00:00