Screening for carriers of cystic fibrosis--a general practitioner's perspective.

abstract：OBJECTIVE:To investigate the effect of immediate feedback from a point of care test for salivary nicotine metabolites in promoting smoking cessation and reduction in tobacco use. DESIGN:Prospective, operator blinded, randomised controlled trial. SETTING:General dental practice, London. PARTICIPANTS:100 adult smokers...

journal_title：BMJ (Clinical research ed.)

authors： Barnfather KD,Cope GF,Chapple IL

更新日期：2005-10-29 00:00:00

abstract：OBJECTIVES:To examine the association of plasma caffeine concentrations during pregnancy with fetal growth and to compare this with relations with reported caffeine intake. DESIGN:Prospective population based study. SETTING:District general hospital, inner London. SUBJECTS:Women booking for delivery between 1982 and...

journal_title：BMJ (Clinical research ed.)

authors： Cook DG,Peacock JL,Feyerabend C,Carey IM,Jarvis MJ,Anderson HR,Bland JM

更新日期：1996-11-30 00:00:00

abstract：OBJECTIVE:To determine the effectiveness of exercise as an intervention in the management of depression. DESIGN:Systematic review and meta-regression analysis of randomised controlled trials obtained from five electronic databases (Medline, Embase, Sports Discus, PsycLIT, Cochrane Library) and through contact with exp...

journal_title：BMJ (Clinical research ed.)

authors： Lawlor DA,Hopker SW

更新日期：2001-03-31 00:00:00

abstract：:Fetomaternal haemorrhage was studied after 68 consecutive fetal intravascular transfusions performed in 20 patients with Rh isoimmunisation. alpha Fetoprotein concentration was assayed in maternal blood taken before, and immediately after each transfusion and three and 24 hours later. An increase of 50% or more in the...

journal_title：BMJ (Clinical research ed.)

authors： Nicolini U,Kochenour NK,Greco P,Letsky EA,Johnson RD,Contreras M,Rodeck CH

更新日期：1988-11-26 00:00:00

abstract：OBJECTIVE:To compare the efficacy of five probiotic preparations recommended to parents in the treatment of acute diarrhoea in children. Design Randomised controlled clinical trial in collaboration with family paediatricians over 12 months. SETTING:Primary care. PARTICIPANTS:Children aged 3-36 months visiting a famil...

journal_title：BMJ (Clinical research ed.)

authors： Canani RB,Cirillo P,Terrin G,Cesarano L,Spagnuolo MI,De Vincenzo A,Albano F,Passariello A,De Marco G,Manguso F,Guarino A

更新日期：2007-08-18 00:00:00

abstract：:The place of balloon dilatation of the aortic valve in the treatment of calcific aortic stenosis is controversial. Thirty two patients (mean age 76) in whom valve replacement was contraindicated were followed up for three to 24 months (mean 8); 25 were in functional class III or IV according to the New York Heart Asso...

journal_title：BMJ (Clinical research ed.)

authors： Sprigings DC,Jackson G,Chambers JB,Monaghan MJ,Thomas SD,Meany TB,Jewitt DE

更新日期：1988-10-22 00:00:00

abstract：OBJECTIVES:To describe the menstrual experience of women referred for menstrual problems, in particular menorrhagia (excessive menstrual loss), and to assess associations with reasons for referral given by their general practitioners, the women's understanding of the reasons for their attendance at the hospital clinics...

journal_title：BMJ (Clinical research ed.)

authors： Warner P,Critchley HO,Lumsden MA,Campbell-Brown M,Douglas A,Murray G

更新日期：2001-07-07 00:00:00

abstract：OBJECTIVE:To characterise the complete case series of influenza A/H7N9 infections as of 27 May 2013, detected by China's national sentinel surveillance system for influenza-like illness. DESIGN:Case series. SETTING:Outpatient clinics and emergency departments of 554 sentinel hospitals across 31 provinces in mainland ...

journal_title：BMJ (Clinical research ed.)

authors： Ip DK,Liao Q,Wu P,Gao Z,Cao B,Feng L,Xu X,Jiang H,Li M,Bao J,Zheng J,Zhang Q,Chang Z,Li Y,Yu J,Liu F,Ni MY,Wu JT,Cowling BJ,Yang W,Leung GM,Yu H

更新日期：2013-06-24 00:00:00

abstract：:An investigation was conducted to determine the vehicle of infection of an outbreak of food poisoning in a large metropolitan building early in 1988. A questionnaire was distributed to 700 people who had eaten in the building during the week of the outbreak, and attack rates for specific food were calculated. Food and...

journal_title：BMJ (Clinical research ed.)

authors： Mitchell E,O'Mahony M,Lynch D,Ward LR,Rowe B,Uttley A,Rogers T,Cunningham DG,Watson R

更新日期：1989-01-14 00:00:00

abstract：:A committee of French bishops has contradicted the Vatican's condemnation of all methods of contraception by acknowledging that condom use may be necessary in order to prevent the spread of HIV and protect against AIDS. The Social Commission of the French Episcopate made this statement in a book entitled AIDS: Societ...

journal_title：BMJ (Clinical research ed.)

authors： Dorozynski A

更新日期：1996-02-24 00:00:00

abstract：:A US organization, Population Action International, is reported in this article to have released findings on the health risks for women in 118 countries. Countries are ranked on 10 indicators, including such indicators as the number of births to women aged under 19 years, the availability of legal abortion, maternal ...

journal_title：BMJ (Clinical research ed.)

authors： Dillner L

更新日期：1995-07-15 00:00:00

abstract：OBJECTIVE:To determine whether rates of suicide changed in Toronto after a barrier was erected at Bloor Street Viaduct, the bridge with the world's second highest annual rate of suicide by jumping after Golden Gate Bridge in San Francisco. DESIGN:Natural experiment. SETTING:City of Toronto and province of Ontario, Ca...

journal_title：BMJ (Clinical research ed.)

authors： Sinyor M,Levitt AJ

更新日期：2010-07-06 00:00:00

abstract：OBJECTIVE:To show the influence of variations in case mix on clinical outcome indicators for patients admitted to hospital with acute stroke. DESIGN:"Before and after" cohort study, with prospective, consecutive identification of patients and prospective follow up; multiple logistic regression analyses to correct for ...

journal_title：BMJ (Clinical research ed.)

authors： Davenport RJ,Dennis MS,Warlow CP

更新日期：1996-06-15 00:00:00

abstract：OBJECTIVE:To investigate the long term effectiveness of integrated disease management delivered in primary care on quality of life in patients with chronic obstructive pulmonary disease (COPD) compared with usual care. DESIGN:24 month, multicentre, pragmatic cluster randomised controlled trial SETTING:40 general prac...

journal_title：BMJ (Clinical research ed.)

authors： Kruis AL,Boland MR,Assendelft WJ,Gussekloo J,Tsiachristas A,Stijnen T,Blom C,Sont JK,Rutten-van Mölken MP,Chavannes NH

更新日期：2014-09-10 00:00:00

abstract：OBJECTIVE:To explore geographical and sociodemographic factors associated with variation in equity in access to total hip and knee replacement surgery. DESIGN:Combining small area estimates of need and provision to explore equity in access to care. SETTING:English census wards. SUBJECTS:Patients throughout England w...

journal_title：BMJ (Clinical research ed.)

authors： Judge A,Welton NJ,Sandhu J,Ben-Shlomo Y

更新日期：2010-08-11 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of an antenatal service using community based breastfeeding peer support workers on initiation of breast feeding. DESIGN:Cluster randomised controlled trial. SETTING:Community antenatal clinics in one primary care trust in a multiethnic, deprived population. PARTICIPANTS:66 ante...

journal_title：BMJ (Clinical research ed.)

authors： MacArthur C,Jolly K,Ingram L,Freemantle N,Dennis CL,Hamburger R,Brown J,Chambers J,Khan K

更新日期：2009-01-30 00:00:00

abstract：OBJECTIVE:To determine the effectiveness of oral rehydration in children with moderate dehydration caused by gastroenteritis, and to compare the complications of oral and intravenous treatment. DESIGN:Randomised controlled trial. SETTING:Emergency department and infectious diseases ward in a large urban teaching hosp...

journal_title：BMJ (Clinical research ed.)

authors： Mackenzie A,Barnes G

更新日期：1991-08-17 00:00:00

abstract：OBJECTIVE:To examine the predictors of long term outcome for patients with the chronic fatigue syndrome. DESIGN:Cohort study. SUBJECTS:139 subjects previously enrolled in two treatment trials; 103 (74%) were reassessed a mean of 3.2 years after start of the trials. SETTING:University hospital referral centre. MAIN ...

journal_title：BMJ (Clinical research ed.)

authors： Wilson A,Hickie I,Lloyd A,Hadzi-Pavlovic D,Boughton C,Dwyer J,Wakefield D

更新日期：1994-03-19 00:00:00

abstract：OBJECTIVE:To compare the efficacy of surgery with disc prosthesis versus non-surgical treatment for patients with chronic low back pain. DESIGN:A prospective randomised multicentre study. SETTING:Five university hospitals in Norway. PARTICIPANTS:173 patients with a history of low back pain for at least one year, Osw...

journal_title：BMJ (Clinical research ed.)

authors： Hellum C,Johnsen LG,Storheim K,Nygaard OP,Brox JI,Rossvoll I,Rø M,Sandvik L,Grundnes O,Norwegian Spine Study Group.

更新日期：2011-05-19 00:00:00

abstract：OBJECTIVES:To determine the prevalence of workplace bullying in an NHS community trust; to examine the association between bullying and occupational health outcomes; and to investigate the relation between support at work and bullying. DESIGN:Questionnaire survey. SETTING:NHS community trust in the south east of Engl...

journal_title：BMJ (Clinical research ed.)

authors： Quine L

更新日期：1999-01-23 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of early treatment for amblyopia in children. DESIGN:Follow up of outcomes of treatment for amblyopia in a randomised controlled trial comparing intensive orthoptic screening at 8, 12, 18, 25, 31, and 37 months (intensive group) with orthoptic screening at 37 months only (control ...

journal_title：BMJ (Clinical research ed.)

authors： Williams C,Northstone K,Harrad RA,Sparrow JM,Harvey I,ALSPAC Study Team.

更新日期：2002-06-29 00:00:00

abstract：:Molecular techniques have revolutionised our knowledge of cell and tissue function in both health and disease. We already have new and powerful treatments based on an understanding of communication between cells by messenger molecules called cytokines. Furthermore, there is great therapeutic promise in defining molecu...

journal_title：BMJ (Clinical research ed.)

authors： Savill J

更新日期：1997-01-18 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of health checks by nurses in reducing risk factors for cardiovascular disease in patients from general practice. DESIGN:Randomised controlled trial. SETTING:Five urban general practices in Bedfordshire. SUBJECTS:2136 patients receiving an initial health check in 1989-91 and sch...

journal_title：BMJ (Clinical research ed.)

authors：

更新日期：1994-01-29 00:00:00

abstract：OBJECTIVES:To identify factors that differentiate between effective and ineffective computerised clinical decision support systems in terms of improvements in the process of care or in patient outcomes. DESIGN:Meta-regression analysis of randomised controlled trials. DATA SOURCES:A database of features and effects of...

journal_title：BMJ (Clinical research ed.)

authors： Roshanov PS,Fernandes N,Wilczynski JM,Hemens BJ,You JJ,Handler SM,Nieuwlaat R,Souza NM,Beyene J,Van Spall HG,Garg AX,Haynes RB

更新日期：2013-02-14 00:00:00

abstract：OBJECTIVE:To investigate differences between hospitals in clinical management of patients admitted with fractured hip and to relate these to mortality at 90 days. DESIGN:A prospective audit of process and outcome of care based on interviews with patients, abstraction from records with standard proforma, and follow up ...

journal_title：BMJ (Clinical research ed.)

authors： Todd CJ,Freeman CJ,Camilleri-Ferrante C,Palmer CR,Hyder A,Laxton CE,Parker MJ,Payne BV,Rushton N

更新日期：1995-04-08 00:00:00

abstract：OBJECTIVE:To assess whether customised mobile phone reminders would improve adherence to therapy and thus decrease virological failure among HIV infected patients starting antiretroviral treatment (ART). DESIGN:Randomised controlled trial among HIV infected patients initiating antiretroviral treatment. SETTING:Three ...

journal_title：BMJ (Clinical research ed.)

authors： Shet A,De Costa A,Kumarasamy N,Rodrigues R,Rewari BB,Ashorn P,Eriksson B,Diwan V,HIVIND Study Team.

更新日期：2014-10-24 00:00:00

abstract：OBJECTIVES:To compare the frequency of discrepancies in retracted reports of clinical trials with those in adjacent unretracted reports in the same journal. DESIGN:Blinded case-control study. SETTING:Journals in PubMed. POPULATION:50 manuscripts, classified on PubMed as retracted clinical trials, paired with 50 adja...

journal_title：BMJ (Clinical research ed.)

authors： Cole GD,Nowbar AN,Mielewczik M,Shun-Shin MJ,Francis DP

更新日期：2015-09-20 00:00:00

abstract：OBJECTIVES:To assess the feasibility and effectiveness of a general practice based, proactive system of asthma care in children. DESIGN:Randomised controlled trial with cluster sampling by general practice. SETTING:General practices in the northern region of the Australian Capital Territory. PARTICIPANTS:174 childre...

journal_title：BMJ (Clinical research ed.)

authors： Glasgow NJ,Ponsonby AL,Yates R,Beilby J,Dugdale P

更新日期：2003-09-20 00:00:00

abstract：OBJECTIVE:To accurately measure the incidence of gastric cancer among patients with gastric precancerous lesions, and to quantify the excess incidence in comparison with people with normal mucosa on endoscopy and a general population. DESIGN:Population based cohort study. SETTING:Population of Sweden using data from ...

journal_title：BMJ (Clinical research ed.)

authors： Song H,Ekheden IG,Zheng Z,Ericsson J,Nyrén O,Ye W

更新日期：2015-07-27 00:00:00

abstract：OBJECTIVES:To explore general practitioners' reasons for recent changes in their prescribing behaviour. DESIGN:Qualitative analysis of semistructured interviews. SETTING:General practice in south east London. SUBJECTS:A heterogeneous sample of 18 general practitioners. RESULTS:Interviewees were able to identify bet...

journal_title：BMJ (Clinical research ed.)

authors： Armstrong D,Reyburn H,Jones R

更新日期：1996-04-13 00:00:00