Incidence of cervical cancer after several negative smear results by age 50: prospective observational study.

abstract：:A doctor who performed an abortion in Poland faces two years in prison and the loss of his medical license for up to 10 years if he is found guilty of violating the new abortion laws introduced in 1993 after a lengthy campaign by the Catholic church and the Christian Democratic Union party. The new laws permit aborti...

journal_title：BMJ (Clinical research ed.)

authors： Gajewski M

更新日期：1995-06-17 00:00:00

abstract：OBJECTIVES:To investigate potential determinants of severe hypoglycaemia, including baseline characteristics, in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial and the association of severe hypoglycaemia with levels of glycated haemoglobin (haemoglobin A(1C)) achieved during therapy. DESIGN:Post ...

journal_title：BMJ (Clinical research ed.)

authors： Miller ME,Bonds DE,Gerstein HC,Seaquist ER,Bergenstal RM,Calles-Escandon J,Childress RD,Craven TE,Cuddihy RM,Dailey G,Feinglos MN,Ismail-Beigi F,Largay JF,O'Connor PJ,Paul T,Savage PJ,Schubart UK,Sood A,Genuth S,ACC

更新日期：2010-01-08 00:00:00

abstract：:This article presents a study on the sexual lifestyle of long distance lorry drivers in India. Using a questionnaire survey method, a total of 5709 consecutive long distance lorry drivers were interviewed by three trained investigators between March 1994 and August 1994. Results showed that 87% (4949 men) of subject...

journal_title：BMJ (Clinical research ed.)

authors： Rao KS,Pilli RD,Rao AS,Chalam PS

更新日期：1999-01-16 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of an integrated care programme, combining a patient directed and a workplace directed intervention, for patients with chronic low back pain. DESIGN:Population based randomised controlled trial. SETTING:Primary care (10 physiotherapy practices, one occupational health service, ...

journal_title：BMJ (Clinical research ed.)

authors： Lambeek LC,van Mechelen W,Knol DL,Loisel P,Anema JR

更新日期：2010-03-16 00:00:00

abstract：OBJECTIVE:To determine whether low dose aspirin protects women aged 65 or more against cognitive decline. DESIGN:Cohort study within both arms of the women's health study, a randomised, double blind, placebo controlled trial of low dose aspirin for the primary prevention of cardiovascular disease and cancer, 1992-5. ...

journal_title：BMJ (Clinical research ed.)

authors： Kang JH,Cook N,Manson J,Buring JE,Grodstein F

更新日期：2007-05-12 00:00:00

abstract：OBJECTIVE:To evaluate the association between migraine and cognitive decline among women. DESIGN:Prospective cohort study. SETTING:Women's Health Study, United States. PARTICIPANTS:6349 women aged 65 or older enrolled in the Women's Health Study who provided information about migraine status at baseline and particip...

journal_title：BMJ (Clinical research ed.)

authors： Rist PM,Kang JH,Buring JE,Glymour MM,Grodstein F,Kurth T

更新日期：2012-08-08 00:00:00

abstract：OBJECTIVES:To compare the effectiveness of in vitro fertilisation with single embryo transfer or in vitro fertilisation in a modified natural cycle with that of intrauterine insemination with controlled ovarian hyperstimulation in terms of a healthy child. DESIGN:Multicentre, open label, three arm, parallel group, ran...

journal_title：BMJ (Clinical research ed.)

authors： Bensdorp AJ,Tjon-Kon-Fat RI,Bossuyt PM,Koks CA,Oosterhuis GJ,Hoek A,Hompes PG,Broekmans FJ,Verhoeve HR,de Bruin JP,van Golde R,Repping S,Cohlen BJ,Lambers MD,van Bommel PF,Slappendel E,Perquin D,Smeenk JM,Pelinck MJ,

更新日期：2015-01-09 00:00:00

abstract：OBJECTIVES:To identify the extent of HIV infection and injecting drug use among female streetworking prostitutes in Glasgow; to estimate the size of the female streetworking prostitute population in the city; and to estimate the number of HIV positive women working as prostitutes on the streets in Glasgow. DESIGN:Obse...

journal_title：BMJ (Clinical research ed.)

authors： McKeganey N,Barnard M,Leyland A,Coote I,Follet E

更新日期：1992-10-03 00:00:00

abstract：OBJECTIVE:To evaluate the primary care communications initiative, which introduced NHSnet to primary care in Scotland. DESIGN:Semi-structured telephone interviews, postal questionnaire. SETTING:All 15 Scottish health boards, random sample of 1 in 3 of all Scottish general practices. PARTICIPANTS:Information manageme...

journal_title：BMJ (Clinical research ed.)

authors： Willmot M,Sullivan F

更新日期：2000-10-07 00:00:00

abstract：OBJECTIVES:To assess the experiences of obstetricians in England and Wales of serum screening for Down's syndrome. DESIGN:Postal questionnaire survey. SUBJECTS:Questionnaires were sent to all practising obstetricians in England and Wales with nonacademic appointments who had not participated in an earlier (randomly s...

journal_title：BMJ (Clinical research ed.)

authors： Green JM

更新日期：1994-09-24 00:00:00

abstract：OBJECTIVE:To determine whether poor reporting of methods in randomised controlled trials reflects on poor methods. DESIGN:Observational study. SETTING:Reports of randomised controlled trials conducted by the Radiation Therapy Oncology Group since its establishment in 1968. PARTICIPANTS:The Radiation Therapy Oncology...

journal_title：BMJ (Clinical research ed.)

authors： Soares HP,Daniels S,Kumar A,Clarke M,Scott C,Swann S,Djulbegovic B,Radiation Therapy Oncology Group.

更新日期：2004-01-03 00:00:00

abstract：OBJECTIVE:This study updates work published in 1998, which found that of 47 rating instruments appearing on websites offering health information, 14 described how they were developed, five provided instructions for use, and none reported the interobserver reliability and construct validity of the measurements. DESIGN:...

journal_title：BMJ (Clinical research ed.)

authors： Gagliardi A,Jadad AR

更新日期：2002-03-09 00:00:00

abstract：OBJECTIVE:To assess body shape trajectories in early and middle life in relation to risk of mortality. DESIGN:Prospective cohort study. SETTING:Nurses' Health Study and Health Professionals Follow-up Study. POPULATION:80 266 women and 36 622 men who recalled their body shape at ages 5, 10, 20, 30, and 40 years and p...

journal_title：BMJ (Clinical research ed.)

authors： Song M,Hu FB,Wu K,Must A,Chan AT,Willett WC,Giovannucci EL

更新日期：2016-05-04 00:00:00

abstract：OBJECTIVE:To assess whether sleep apnoea syndrome is an independent risk factor for hypertension. DESIGN:Population study. SETTING:Sleep clinic in Toronto. PARTICIPANTS:2,677 adults, aged 20-85 years, referred to the sleep clinic with suspected sleep apnoea syndrome. OUTCOME MEASURES:Medical history, demographic da...

journal_title：BMJ (Clinical research ed.)

authors： Lavie P,Herer P,Hoffstein V

更新日期：2000-02-19 00:00:00

abstract：OBJECTIVE:To determine the appropriateness of referrals from general practice to hospital outpatient departments. DESIGN:Prospective audit of referrals from a group practice over one year. SETTING:Six handed practice in a southern coastal town. SUBJECTS:All patients referred during the study period for whom a copy o...

journal_title：BMJ (Clinical research ed.)

authors： Emmanuel J,Walter N

更新日期：1989-09-16 00:00:00

abstract：OBJECTIVE:To determine the prevalence of sexually transmitted diseases in patients with normal and abnormal cervical smears. DESIGN:A prospective study of asymptomatic women with normal cervical smears attending their general practitioner and newly referred patients with abnormal smears attending a colposcopy clinic. ...

journal_title：BMJ (Clinical research ed.)

authors： Smith JR,Murdoch J,Carrington D,Frew CE,Dougall AJ,MacKinnon H,Baillie D,Byford DM,Forrest CA,Davis JA

更新日期：1991-01-12 00:00:00

abstract：OBJECTIVES:To assess the performance of a panel of common single nucleotide polymorphisms (genotypes) associated with type 2 diabetes in distinguishing incident cases of future type 2 diabetes (discrimination), and to examine the effect of adding genetic information to previously validated non-genetic (phenotype based)...

journal_title：BMJ (Clinical research ed.)

authors： Talmud PJ,Hingorani AD,Cooper JA,Marmot MG,Brunner EJ,Kumari M,Kivimäki M,Humphries SE

更新日期：2010-01-14 00:00:00

abstract：:Cancers of unknown primary (CUPs) are histologically confirmed, metastatic malignancies with a primary tumor site that is unidentifiable on the basis of standard evaluation and imaging studies. CUP comprises 2-5% of all diagnosed cancers worldwide and is characterized by early and aggressive metastasis. Current standa...

journal_title：BMJ (Clinical research ed.)

authors： Lee MS,Sanoff HK

更新日期：2020-12-07 00:00:00

abstract：OBJECTIVE:To assess whether using intensive blood pressure targets leads to lower blood pressure in a community population of people with prevalent cerebrovascular disease. DESIGN:Open label randomised controlled trial. SETTING:99 general practices in England, with participants recruited in 2009-11. PARTICIPANTS:Peo...

journal_title：BMJ (Clinical research ed.)

authors： Mant J,McManus RJ,Roalfe A,Fletcher K,Taylor CJ,Martin U,Virdee S,Greenfield S,Hobbs FD

更新日期：2016-02-24 00:00:00

abstract：OBJECTIVE:To examine the relation between energy intake in childhood and adult mortality from cancer. STUDY DESIGN:Cohort study. SETTING:16 rural and urban centres in England and Scotland. SUBJECTS:3834 people who took part in Lord Boyd Orr's Carnegie survey of family diet and health in prewar Britain between 1937 a...

journal_title：BMJ (Clinical research ed.)

authors： Frankel S,Gunnell DJ,Peters TJ,Maynard M,Davey Smith G

更新日期：1998-02-14 00:00:00

abstract：STUDY QUESTION:What are the long term trends in the total (live births, fetal deaths, and terminations of pregnancy for fetal anomaly) and live birth prevalence of neural tube defects (NTD) in Europe, where many countries have issued recommendations for folic acid supplementation but a policy for mandatory folic acid f...

journal_title：BMJ (Clinical research ed.)

authors： Khoshnood B,Loane M,de Walle H,Arriola L,Addor MC,Barisic I,Beres J,Bianchi F,Dias C,Draper E,Garne E,Gatt M,Haeusler M,Klungsoyr K,Latos-Bielenska A,Lynch C,McDonnell B,Nelen V,Neville AJ,O'Mahony MT,Queisser-Luf

更新日期：2015-11-24 00:00:00

abstract：OBJECTIVE:To determine whether failure to adequately adjust for a reported 40% misclassification of use of in vitro fertilisation (IVF) as reported in a Swedish study could have led to a false finding that folic acid increases dizygotic twinning. DESIGN:Modelling with population based data. SETTING:Swedish vital reco...

journal_title：BMJ (Clinical research ed.)

authors： Berry RJ,Kihlberg R,Devine O

更新日期：2005-04-09 00:00:00

abstract：OBJECTIVE:To assess general practitioners' decisions to request lumbar spine radiographs according to the guidelines of the Royal College of Radiologists. DESIGN:Prospective questionnaire survey of outpatients attending for lumbar spine radiography. SETTING:London community hospital. SUBJECTS:100 consecutive adult o...

journal_title：BMJ (Clinical research ed.)

authors： Halpin SF,Yeoman L,Dundas DD

更新日期：1991-10-05 00:00:00

abstract：:Two patients with acute major, disabling cerebral infarction with presumed middle cerebral artery occlusion were treated with the clot specific thrombolytic agent tissue plasminogen activator roughly three and a half hours after the onset of symptoms. Both patients had a normal computed tomography (CT) scan before tre...

journal_title：BMJ (Clinical research ed.)

authors： Koudstaal PJ,Stibbe J,Vermeulen M

更新日期：1988-12-17 00:00:00

abstract：OBJECTIVE:To increase understanding of how the prison environment influences the mental health of prisoners and prison staff. DESIGN:Qualitative study with focus groups. SETTING:A local prison in southern England. PARTICIPANTS:Prisoners and prison staff. RESULTS:Prisoners reported that long periods of isolation wit...

journal_title：BMJ (Clinical research ed.)

authors： Nurse J,Woodcock P,Ormsby J

更新日期：2003-08-30 00:00:00

abstract：OBJECTIVES:To determine the clinical and radiological features of severe acute respiratory syndrome (SARS) and to evaluate the accuracy of the World Health Organization's guidelines on defining cases of SARS. DESIGN:Prospective observational study. SETTING:A newly set up SARS screening clinic in the emergency departm...

journal_title：BMJ (Clinical research ed.)

authors： Rainer TH,Cameron PA,Smit D,Ong KL,Hung AN,Nin DC,Ahuja AT,Si LC,Sung JJ

更新日期：2003-06-21 00:00:00

abstract：OBJECTIVES:To determine clinical correlates and outcome of hypoxaemia in children admitted to hospital with an acute lower respiratory tract infection. DESIGN:Prospective cohort study. SETTING:Paediatric wards of the Royal Victoria Hospital and the hospital of the Medical Research Council's hospital in Banjul, the Ga...

journal_title：BMJ (Clinical research ed.)

authors： Usen S,Weber M,Mulholland K,Jaffar S,Oparaugo A,Omosigho C,Adegbola R,Greenwood B

更新日期：1999-01-09 00:00:00

abstract：:Objective To determine whether educational attainment is a causal risk factor in the development of coronary heart disease.Design Mendelian randomisation study, using genetic data as proxies for education to minimise confounding.Setting The main analysis used genetic data from two large consortia (CARDIoGRAMplusC4D an...

journal_title：BMJ (Clinical research ed.)

authors： Tillmann T,Vaucher J,Okbay A,Pikhart H,Peasey A,Kubinova R,Pajak A,Tamosiunas A,Malyutina S,Hartwig FP,Fischer K,Veronesi G,Palmer T,Bowden J,Davey Smith G,Bobak M,Holmes MV

更新日期：2017-08-30 00:00:00

abstract：OBJECTIVE:To examine the associations of a vegetarian diet and dietary fibre intake with risk of diverticular disease. DESIGN:Prospective cohort study. SETTING:The EPIC-Oxford study, a cohort of mainly health conscious participants recruited from around the United Kingdom. PARTICIPANTS:47,033 men and women living in...

journal_title：BMJ (Clinical research ed.)

authors： Crowe FL,Appleby PN,Allen NE,Key TJ

更新日期：2011-07-19 00:00:00

abstract：OBJECTIVE:To compare the efficacy of five probiotic preparations recommended to parents in the treatment of acute diarrhoea in children. Design Randomised controlled clinical trial in collaboration with family paediatricians over 12 months. SETTING:Primary care. PARTICIPANTS:Children aged 3-36 months visiting a famil...

journal_title：BMJ (Clinical research ed.)

authors： Canani RB,Cirillo P,Terrin G,Cesarano L,Spagnuolo MI,De Vincenzo A,Albano F,Passariello A,De Marco G,Manguso F,Guarino A

更新日期：2007-08-18 00:00:00