Painful crises in sickle cell disease--patients' perspectives.

Abstract:

:One hundred and two patients returned structured questionnaires sent to clinics for sickle cell disease in the United Kingdom in order to gain greater insight into the patients' perception of painful crises. Most patients who suffer pain crises experience a prodromal stage that should be investigated further to find out if prophylaxis is possible. Cold, exertion, and tiredness were the most important precipitating factors. Despite the increase in the amount of knowledge about sickle cell disease in recent years, and though 29 out of 88 patients (30-40%) believed that medical services were improving, 33 out of 88 (30-40%) were still experiencing long delays in being treated in hospital. A third of patients do not seem to receive adequate pain relief.

journal_name

BMJ

authors

Murray N,May A

doi

10.1136/bmj.297.6646.452

subject

Has Abstract

pub_date

1988-08-13 00:00:00

pages

452-4

issue

6646

eissn

0959-8138

issn

1756-1833

journal_volume

297

pub_type

杂志文章
  • Period trends in rate of suicide in first 28 days after discharge from psychiatric hospital in Scotland, 1968-92.

    abstract:OBJECTIVE:To examine period trends in the rate of suicide in the first 28 days after discharge from psychiatric hospital. DESIGN:Cohort study of patients discharged from psychiatric hospital. SETTING:Scotland. SUBJECTS:All patients aged 15-84 who were discharged from Scottish psychiatric hospitals during 1968 to 199...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章

    doi:10.1136/bmj.311.7001.357

    authors: Geddes JR,Juszczak E

    更新日期:1995-08-05 00:00:00

  • Proactive asthma care in childhood: general practice based randomised controlled trial.

    abstract:OBJECTIVES:To assess the feasibility and effectiveness of a general practice based, proactive system of asthma care in children. DESIGN:Randomised controlled trial with cluster sampling by general practice. SETTING:General practices in the northern region of the Australian Capital Territory. PARTICIPANTS:174 childre...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/bmj.327.7416.659

    authors: Glasgow NJ,Ponsonby AL,Yates R,Beilby J,Dugdale P

    更新日期:2003-09-20 00:00:00

  • Incidence of cancer among Finnish airline cabin attendants, 1967-92.

    abstract:OBJECTIVE:To assess whether occupational exposure among commercial airline cabin attendants are associated with risk of cancer. DESIGN:Record linkage study. SETTING:Finland. SUBJECTS-1577 female and 187 male cabin attendants who had worked for the Finnish airline companies. MAIN OUTCOME MEASURE:Standardised incidenc...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章

    doi:10.1136/bmj.311.7006.649

    authors: Pukkala E,Auvinen A,Wahlberg G

    更新日期:1995-09-09 00:00:00

  • Household based treatment of drinking water with flocculant-disinfectant for preventing diarrhoea in areas with turbid source water in rural western Kenya: cluster randomised controlled trial.

    abstract:OBJECTIVE:To compare the effect on prevalence of diarrhoea and mortality of household based treatment of drinking water with flocculant-disinfectant, sodium hypochlorite, and standard practices in areas with turbid water source in Africa. DESIGN:Cluster randomised controlled trial over 20 weeks. SETTING:Family compou...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1136/bmj.38512.618681.E0

    authors: Crump JA,Otieno PO,Slutsker L,Keswick BH,Rosen DH,Hoekstra RM,Vulule JM,Luby SP

    更新日期:2005-09-03 00:00:00

  • Group cognitive behavioural courses may reduce fatigue from rheumatoid arthritis.

    abstract::The studyHewlett S, Almeida C, Ambler N, et al. Reducing arthritis fatigue impact: two-year randomised controlled trial of cognitive behavioural approaches by rheumatology teams (RAFT). Ann Rheum Dis 2019;78:465-72.Hewlett S, Almeida C, Ambler N, et al. Group cognitive behavioural programme to reduce the impact of rhe...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章,随机对照试验

    doi:10.1136/bmj.m512

    authors: Cook R,Davidson P,Martin R,NIHR Dissemination Centre.

    更新日期:2020-03-06 00:00:00

  • What worries parents when their preschool children are acutely ill, and why: a qualitative study.

    abstract:OBJECTIVE:To identify and explore parents' concerns when young children become acutely ill. DESIGN:Qualitative study making use of semi-structured one to one and group interviews with parents of preschool children. SETTING:Disadvantaged inner city community. SUBJECTS:95 parents of preschool children. RESULTS:Fever,...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章

    doi:10.1136/bmj.313.7063.983

    authors: Kai J

    更新日期:1996-10-19 00:00:00

  • Content and quality of 2000 controlled trials in schizophrenia over 50 years.

    abstract:OBJECTIVE:To provide a comprehensive survey of the content and quality of intervention studies relevant to the treatment of schizophrenia. DESIGN:Data were extracted from 2000 trials on the Cochrane Schizophrenia Group's register. MAIN OUTCOME MEASURES:Type and date of publication, country of origin, language, size o...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章

    doi:10.1136/bmj.317.7167.1181

    authors: Thornley B,Adams C

    更新日期:1998-10-31 00:00:00

  • Accuracy of mini peak flow meters in indicating changes in lung function in children with asthma.

    abstract:OBJECTIVE:To assess whether mini flow meters used to measure peak expiratory flow can track changes in lung function and indicate clinically important changes. DESIGN:Comparison of measurements with a spirometer and different brands of mini flow meter; the meters were allocated to subjects haphazardly. SUBJECTS:12 bo...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 临床试验,杂志文章

    doi:10.1136/bmj.308.6928.572

    authors: Sly PD,Cahill P,Willet K,Burton P

    更新日期:1994-02-26 00:00:00

  • Association between Apgar scores of 7 to 9 and neonatal mortality and morbidity: population based cohort study of term infants in Sweden.

    abstract:OBJECTIVE:To investigate associations between Apgar scores of 7, 8, and 9 (versus 10) at 1, 5, and 10 minutes, and neonatal mortality and morbidity. DESIGN:Population based cohort study. SETTING:Sweden. PARTICIPANTS:1 551 436 non-malformed live singleton infants, born at term (≥37 weeks' gestation) between 1999 and ...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章

    doi:10.1136/bmj.l1656

    authors: Razaz N,Cnattingius S,Joseph KS

    更新日期:2019-05-07 00:00:00

  • Setting priorities, can Britain learn from Sweden?

    abstract::The Swedish government recently published a report on priorities in health care. It was written by a cross party group of politicians and drew extensively on the views of the public, health professionals, experience of earlier local exercises in priority setting, and research based evidence. It laid down an ethical fr...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章

    doi:10.1136/bmj.312.7032.691

    authors: McKee M,Figueras J

    更新日期:1996-03-16 00:00:00

  • Making an advance directive.

    abstract::The introduction in Britain of advance directives--which allow a person to state in advance of becoming incompetent that they wish to take part in treatment decisions when no longer mentally competent--has now been advocated by the medical and legal establishments. The practical application of directives relating to h...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章

    doi:10.1136/bmj.310.6974.236

    authors: Robertson GS

    更新日期:1995-01-28 00:00:00

  • Consumers' estimation of calorie content at fast food restaurants: cross sectional observational study.

    abstract:OBJECTIVE:To investigate estimation of calorie (energy) content of meals from fast food restaurants in adults, adolescents, and school age children. DESIGN:Cross sectional study of repeated visits to fast food restaurant chains. SETTING:89 fast food restaurants in four cities in New England, United States: McDonald's...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章

    doi:10.1136/bmj.f2907

    authors: Block JP,Condon SK,Kleinman K,Mullen J,Linakis S,Rifas-Shiman S,Gillman MW

    更新日期:2013-05-23 00:00:00

  • Secondary prevention of coronary heart disease in older patients after the national service framework: population based study.

    abstract:OBJECTIVE:To examine the extent of uptake of medication for secondary prevention of coronary heart disease in older British men and women before (1998-2001) and after (2003) the implementation of the national service framework. DESIGN:Two population based, longitudinal studies of men and women aged 60-79 in 1998-2001,...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章,多中心研究

    doi:10.1136/bmj.38704.770127.BE

    authors: Ramsay SE,Whincup PH,Lawlor DA,Papacosta O,Lennon LT,Thomas MC,Ebrahim S,Morris RW

    更新日期:2006-01-21 00:00:00

  • Commodes: inconvenient conveniences.

    abstract:OBJECTIVES:To investigate use of commodes and attitudes of users and carers to them. DESIGN:Interview with semi-structured questionnaire of subjects supplied with commodes from Leeds community appliance centre. SUBJECTS:140 users of a commode and 105 of their carers. RESULTS:Main reasons for being supplied with a co...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章

    doi:10.1136/bmj.307.6914.1258

    authors: Naylor JR,Mulley GP

    更新日期:1993-11-13 00:00:00

  • Outcomes of elective surgery undertaken in independent sector treatment centres and NHS providers in England: audit of patient outcomes in surgery.

    abstract:OBJECTIVE:To compare characteristics of patients and outcomes after elective surgery in independent sector treatment centres (ISTCs) and NHS providers. DESIGN:Follow-up study with outcomes reported by patients three to six months after surgery. SETTING:25 ISTCs and 72 NHS providers in England. Population Consecutive ...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章

    doi:10.1136/bmj.d6404

    authors: Chard J,Kuczawski M,Black N,van der Meulen J,POiS Audit Steering Committee.

    更新日期:2011-10-19 00:00:00

  • An adult with a neck lump.

    abstract::A 40 year old man presents with a 1 cm tender soft swelling in the lateral neck region. This developed seven days after the onset of a tonsillitis episode that has now resolved. He has a 20 pack-year smoking history and consumes minimal alcohol. Examination is otherwise normal. ...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章

    doi:10.1136/bmj.f5473

    authors: Dwivedi RC,Masterson L,Alam M,Jani P

    更新日期:2013-10-28 00:00:00

  • Influence of maternal age at delivery and birth order on risk of type 1 diabetes in childhood: prospective population based family study. Bart's-Oxford Family Study Group.

    abstract:OBJECTIVES:To examine the influence of parental age at delivery and birth order on subsequent risk of childhood diabetes. DESIGN:Prospective population based family study. SETTING:Area formerly administered by the Oxford Regional Health Authority. PARTICIPANTS:1375 families in which one child or more had diabetes. O...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章

    doi:10.1136/bmj.321.7258.420

    authors: Bingley PJ,Douek IF,Rogers CA,Gale EA

    更新日期:2000-08-12 00:00:00

  • Incidence of cervical cancer after several negative smear results by age 50: prospective observational study.

    abstract:OBJECTIVE:To determine the incidence of cervical cancer after several negative cervical smear tests at different ages. DESIGN:Prospective observational study of incidence of cervical cancer after the third consecutive negative result based on individual level data in a national registry of histopathology and cytopatho...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章,多中心研究

    doi:10.1136/bmj.b1354

    authors: Rebolj M,van Ballegooijen M,Lynge E,Looman C,Essink-Bot ML,Boer R,Habbema D

    更新日期:2009-04-24 00:00:00

  • Effects of preventive home visits to elderly people living in the community: systematic review.

    abstract:OBJECTIVE:To assess the effects of preventive home visits to elderly people living in the community. DESIGN:Systematic review. SETTING:15 trials retrieved from Medline, Embase, and the Cochrane controlled trial register. MAIN OUTCOME MEASURES:Physical function, psychosocial function, falls, admissions to institution...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章,评审

    doi:10.1136/bmj.320.7237.754

    authors: van Haastregt JC,Diederiks JP,van Rossum E,de Witte LP,Crebolder HF

    更新日期:2000-03-18 00:00:00

  • Effect of routine zinc supplementation on pneumonia in children aged 6 months to 3 years: randomised controlled trial in an urban slum.

    abstract:OBJECTIVES:To evaluate the effect of daily zinc supplementation in children on the incidence of acute lower respiratory tract infections and pneumonia. DESIGN:Double masked, randomised placebo controlled trial. SETTING:A slum community in New Delhi, India. PARTICIPANTS:2482 children aged 6 to 30 months. INTERVENTIO...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/bmj.324.7350.1358

    authors: Bhandari N,Bahl R,Taneja S,Strand T,Mølbak K,Ulvik RJ,Sommerfelt H,Bhan MK

    更新日期:2002-06-08 00:00:00

  • Improving generalist end of life care: national consultation with practitioners, commissioners, academics, and service user groups.

    abstract:OBJECTIVE:To identify major concerns of national and local importance in the provision, commissioning, research, and use of generalist end of life care. DESIGN:A national consultation and prioritising exercise using a modified form of the nominal group technique. PARTICIPANTS:Healthcare practitioners, commissioners, ...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章,多中心研究

    doi:10.1136/bmj.a1720

    authors: Shipman C,Gysels M,White P,Worth A,Murray SA,Barclay S,Forrest S,Shepherd J,Dale J,Dewar S,Peters M,White S,Richardson A,Lorenz K,Koffman J,Higginson IJ

    更新日期:2008-10-01 00:00:00

  • The demand for neonatal intensive care.

    abstract::In a one year prospective study within the Trent Regional Health Authority the demand for neonatal intensive care was estimated to be 1.1 cots per 1000 births. Intensive care level 1 (as defined by the British Paediatric Association and British Association for Perinatal Paediatrics) was determined by two separate tech...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章

    doi:10.1136/bmj.299.6711.1305

    authors: Field DJ,Hodges S,Mason E,Burton P,Yates J,Wale S

    更新日期:1989-11-25 00:00:00

  • Absorption of non-haem iron from food during normal pregnancy.

    abstract:OBJECTIVE:To determine whether the increased iron demands of pregnancy could be met by increased absorption from dietary sources. DESIGN AND SETTING:Longitudinal prospective study in the research unit of a maternity hospital. SUBJECTS:12 normal pregnant women. INTERVENTIONS:At 12, 24, and 36 weeks' gestation (within...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章

    doi:10.1136/bmj.309.6947.79

    authors: Barrett JF,Whittaker PG,Williams JG,Lind T

    更新日期:1994-07-09 00:00:00

  • Other cities, same problems.

    abstract::London's health care problems, particularly underfunding, are mirrored in other major cities in the United Kingdom and abroad. None has found the perfect solution, but the debates on the Tomlinson report provide an opportunity to review how to manage the three major areas of service provision, medical education, and r...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章

    doi:10.1136/bmj.306.6871.199

    authors: Maxwell R

    更新日期:1993-01-16 00:00:00

  • Exposure to low dose computed tomography for lung cancer screening and risk of cancer: secondary analysis of trial data and risk-benefit analysis.

    abstract::Objective To estimate the cumulative radiation exposure and lifetime attributable risk of cancer incidence associated with lung cancer screening using annual low dose computed tomography (CT).Design Secondary analysis of data from a lung cancer screening trial and risk-benefit analysis.Setting 10 year, non-randomised,...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章

    doi:10.1136/bmj.j347

    authors: Rampinelli C,De Marco P,Origgi D,Maisonneuve P,Casiraghi M,Veronesi G,Spaggiari L,Bellomi M

    更新日期:2017-02-08 00:00:00

  • Cardiovascular safety of central nervous system stimulants in children and adolescents: population based cohort study.

    abstract:OBJECTIVES:To evaluate the cardiac safety of central nervous system stimulants in children and adolescents. DESIGN:Population based retrospective cohort study. SETTING:Automated healthcare claims data from 1,219,847 children and young people eligible for 28 state Medicaid programmes from 1999 to 2006 linked to the So...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章

    doi:10.1136/bmj.e4627

    authors: Winterstein AG,Gerhard T,Kubilis P,Saidi A,Linden S,Crystal S,Zito J,Shuster JJ,Olfson M

    更新日期:2012-07-18 00:00:00

  • Lifestyle changes may be more important than drugs for mild hypertension.

    abstract::The studySheppard JP, Stevens S, Stevens R, Martin U, Mant J, Hobbs R, McManus R. Benefits and harms of antihypertensive treatment in low-risk patients with mild hypertension.Published on 1 December 2018 JAMA Intern Med 2018;178:1626-34.This project was funded by a grant from the National Institute for Health Research...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章

    doi:10.1136/bmj.l571

    authors: Cook R,Lamont T,Martin R,NIHR Dissemination Centre.

    更新日期:2019-02-15 00:00:00

  • Cumulative funnel plots for the early detection of interoperator variation: retrospective database analysis of observed versus predicted results of percutaneous coronary intervention.

    abstract:OBJECTIVE:To use funnel plots and cumulative funnel plots to compare in-hospital outcome data for operators undertaking percutaneous coronary interventions with predicted results derived from a validated risk score to allow for early detection of variation in performance. DESIGN:Analysis of prospectively collected dat...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章

    doi:10.1136/bmj.39512.529120.BE

    authors: Kunadian B,Dunning J,Roberts AP,Morley R,Twomey D,Hall JA,Sutton AG,Wright RA,Muir DF,de Belder MA

    更新日期:2008-04-26 00:00:00

  • Tea drinking habits and oesophageal cancer in a high risk area in northern Iran: population based case-control study.

    abstract:OBJECTIVE:To investigate the association between tea drinking habits in Golestan province, northern Iran, and risk of oesophageal squamous cell carcinoma. DESIGN:Population based case-control study. In addition, patterns of tea drinking and temperature at which tea was drunk were measured among healthy participants in...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章

    doi:10.1136/bmj.b929

    authors: Islami F,Pourshams A,Nasrollahzadeh D,Kamangar F,Fahimi S,Shakeri R,Abedi-Ardekani B,Merat S,Vahedi H,Semnani S,Abnet CC,Brennan P,Møller H,Saidi F,Dawsey SM,Malekzadeh R,Boffetta P

    更新日期:2009-03-26 00:00:00

  • Mobile phone use and risk of glioma in adults: case-control study.

    abstract:OBJECTIVE:To investigate the risk of glioma in adults in relation to mobile phone use. DESIGN:Population based case-control study with collection of personal interview data. SETTING:Five areas of the United Kingdom. PARTICIPANTS:966 people aged 18 to 69 years diagnosed with a glioma from 1 December 2000 to 29 Februa...

    journal_title:BMJ (Clinical research ed.)

    pub_type: 杂志文章,多中心研究

    doi:10.1136/bmj.38720.687975.55

    authors: Hepworth SJ,Schoemaker MJ,Muir KR,Swerdlow AJ,van Tongeren MJ,McKinney PA

    更新日期:2006-04-15 00:00:00