Vascular Calcification as an Underrecognized Risk Factor for Frailty in 1783 Community-Dwelling Elderly Individuals.

abstract：:Background Although many patients with coronary artery disease are using statins before off-pump coronary artery bypass grafting ( OPCAB ) following current guidelines, recent studies have raised concerns regarding adverse effects of preoperative statins on postoperative kidney function. We evaluated the effects of pr...

journal_title：Journal of the American Heart Association

authors： Park J,Lee JH,Kim KA,Lee SH,Lee YT,Kim WS,Min JJ

更新日期：2019-04-02 00:00:00

abstract：:Background Characterizing associations of sleep characteristics with blood-glucose-level factors among blacks may clarify the underlying mechanisms of impaired glucose metabolism and help identify treatment targets to prevent diabetes mellitus in blacks. Methods and Results Cross-sectional analyses were conducted in 7...

journal_title：Journal of the American Heart Association

authors： Yano Y,Gao Y,Johnson DA,Carnethon M,Correa A,Mittleman MA,Sims M,Mostofsky E,Wilson JG,Redline S

更新日期：2020-05-05 00:00:00

abstract：:Background Cardiac hypertrophy has been recognized as an important independent risk factor for the development of heart failure and increases the risk of cardiac morbidity and mortality. A disintegrin and metalloprotease 23 (ADAM23), a member of ADAM family, is involved in cancer and neuronal differentiation. Although...

journal_title：Journal of the American Heart Association

authors： Xiang M,Luo H,Wu J,Ren L,Ding X,Wu C,Chen J,Chen S,Zhang H,Yu L,Zou Y,Xu H,Ye P,Chen M,Xia J

更新日期：2018-09-18 00:00:00

abstract：BACKGROUND:There is accumulating evidence that serum levels of non-high-density lipoprotein cholesterol (non-HDL-C) are a more accurate predictor of cardiovascular outcomes when compared with low-density lipoprotein cholesterol. However, we recently found that higher serum concentrations of triglycerides are associated...

journal_title：Journal of the American Heart Association

authors： Chang TI,Streja E,Ko GJ,Naderi N,Rhee CM,Kovesdy CP,Kashyap ML,Vaziri ND,Kalantar-Zadeh K,Moradi H

更新日期：2018-06-09 00:00:00

abstract：:Background The management of the cardiorenal syndrome in advanced heart failure is challenging, and the role of inotropic drugs has not been fully defined. Our aim was to compare the renal effects of levosimendan versus dobutamine in patients with heart failure and renal impairment. Methods and Results In a randomized...

journal_title：Journal of the American Heart Association

authors： Lannemyr L,Ricksten SE,Rundqvist B,Andersson B,Bartfay SE,Ljungman C,Dahlberg P,Bergh N,Hjalmarsson C,Gilljam T,Bollano E,Karason K

更新日期：2018-08-21 00:00:00

abstract：:Background Hyperhomocysteinemia is a risk factor for ischemic stroke; however, a targeted treatment strategy is lacking partly because of limited understanding of the causal role of homocysteine in cerebrovascular pathogenesis. Methods and Results In a genetic model of cystathionine beta synthase (CBS) deficiency, we ...

journal_title：Journal of the American Heart Association

authors： Gu SX,Sonkar VK,Katare PB,Kumar R,Kruger WD,Arning E,Bottiglieri T,Lentz SR,Dayal S

更新日期：2020-02-18 00:00:00

abstract：BACKGROUND:The impact of dispatcher-assisted bystander cardiopulmonary resuscitation (CPR) on neurological outcomes in children is unclear. We investigated whether dispatcher-assisted bystander CPR shows favorable neurological outcomes (Cerebral Performance Category scale 1 or 2) in children with out-of-hospital cardia...

journal_title：Journal of the American Heart Association

authors： Goto Y,Maeda T,Goto Y

更新日期：2014-04-30 00:00:00

abstract：BACKGROUND:Although generic medications are approved based on bioequivalence with brand-name medications, there remains substantial concern regarding their clinical effectiveness and safety. Lipitor(®), available as generic atorvastatin, is one of the most commonly prescribed statins. Therefore, we compared the effecti...

journal_title：Journal of the American Heart Association

authors： Jackevicius CA,Tu JV,Krumholz HM,Austin PC,Ross JS,Stukel TA,Koh M,Chong A,Ko DT

更新日期：2016-04-19 00:00:00

abstract：BACKGROUND:Little is known about causality and pathological mechanism underlying association of postinfarct fever with myocardial injury in patients with ST-segment elevation myocardial infarction. METHODS AND RESULTS:In 276 patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocar...

journal_title：Journal of the American Heart Association

authors： Jang WJ,Yang JH,Song YB,Chun WJ,Oh JH,Park YH,Lee MR,Hwang JK,Hwang JW,Hahn JY,Choi SH,Lee SC,Choe YH,Gwon HC

更新日期：2017-04-24 00:00:00

abstract：BACKGROUND:Pediatric syncope is common. Cardiac causes are rarely found. We describe and assess a pragmatic approach to these patients first seen by a pediatric cardiologist in the New England region, using Standardized Clinical Assessment and Management Plans (SCAMPs). METHODS AND RESULTS:Ambulatory patients aged 7 t...

journal_title：Journal of the American Heart Association

authors： Paris Y,Toro-Salazar OH,Gauthier NS,Rotondo KM,Arnold L,Hamershock R,Saudek DE,Fulton DR,Renaud A,Alexander ME,New England Congenital Cardiology Association (NECCA).

更新日期：2016-02-19 00:00:00

abstract：:Background Hospitals in the United States vary in their use of intensive care units (ICUs) for hemodynamically stable patients with non-ST-segment-elevation myocardial infarction (NSTEMI). The association between ICU use and long-term outcomes after NSTEMI is unknown. Methods and Results Using data from the National C...

journal_title：Journal of the American Heart Association

authors： Fanaroff AC,Chen AY,van Diepen S,Peterson ED,Wang TY

更新日期：2020-03-17 00:00:00

abstract：BACKGROUND:People with end-stage renal disease (ESRD) are at risk for advanced heart failure, but little is known about use and outcomes of durable mechanical circulatory support in this setting. We examined use and outcomes of implantable ventricular assist devices (VADs) in a national ESRD cohort. METHODS AND RESULT...

journal_title：Journal of the American Heart Association

authors： Walther CP,Niu J,Winkelmayer WC,Cheema FH,Nair AP,Morgan JA,Fedson SE,Deswal A,Navaneethan SD

更新日期：2018-07-06 00:00:00

abstract：:Background To determine if accelerometer measured sedentary behavior (SED), light-intensity physical activity (LPA), and moderate-to-vigorous-intensity physical activity (MVPA) in midlife is prospectively associated with cognitive function. Methods and Results Participants were 1970 adults enrolled in the CARDIA (Coro...

journal_title：Journal of the American Heart Association

authors： Whitaker KM,Zhang D,Pettee Gabriel K,Ahrens M,Sternfeld B,Sidney S,Jacobs DR Jr,Palta P,Yaffe K

更新日期：2021-01-20 00:00:00

abstract：:Background Coronary artery disease remains a major cause of death despite better outcomes of ST-segment-elevation myocardial infarction (STEMI). We aimed to analyze data from the Ruti-STEMI registry of in-hospital, 28-day, and 1-year events in patients with STEMI over the past 3 decades in Catalonia, Spain, to assess ...

journal_title：Journal of the American Heart Association

authors： García-García C,Oliveras T,Serra J,Vila J,Rueda F,Cediel G,Labata C,Ferrer M,Carrillo X,Dégano IR,De Diego O,El Ouaddi N,Montero S,Mauri J,Elosua R,Lupón J,Bayes-Genis A,Ruti‐STEMI Investigators †.

更新日期：2020-10-20 00:00:00

abstract：:Background Bleeding is a common, morbid, and costly complication of percutaneous coronary intervention. While bleeding avoidance strategies ( BAS ) are effective, they are used paradoxically less in patients at high risk of bleeding. Whether a patient-centered approach to specifically increase the risk-concordant use ...

journal_title：Journal of the American Heart Association

authors： Amin AP,Miller S,Rahn B,Caruso M,Pierce A,Sorensen K,Kurz H,Zajarias A,Bach R,Singh J,Lasala JM,Kulkarni H,Crimmins-Reda P

更新日期：2018-11-06 00:00:00

abstract：BACKGROUND:Although choline metabolism has been associated with atherosclerotic heart disease, less research attention has been paid to the associations of choline and its oxidative metabolite betaine with cardiac arrhythmias. METHODS AND RESULTS:We evaluated associations of plasma concentrations and dietary intakes o...

journal_title：Journal of the American Heart Association

authors： Zuo H,Svingen GFT,Tell GS,Ueland PM,Vollset SE,Pedersen ER,Ulvik A,Meyer K,Nordrehaug JE,Nilsen DWT,Bønaa KH,Nygård O

更新日期：2018-04-12 00:00:00

abstract：:Background Atrial fibrillation (AF) has been shown to be associated with an increased risk of dementia as well as Alzheimer disease in observational studies. Whether this association reflects causal association is still unclear. The purpose of this study was to examine the causal association of AF with Alzheimer disea...

journal_title：Journal of the American Heart Association

authors： Pan Y,Wang Y,Wang Y

更新日期：2020-01-21 00:00:00

abstract：:Background Global fractional flow reserve (FFR) (ie, the sum of the FFR values in the 3 major coronary arteries) is a physiologic correlate of global atherosclerotic burden. The objective of the present study was to investigate the value of global FFR in predicting long-term clinical outcome of patients with stable co...

journal_title：Journal of the American Heart Association

authors： Fournier S,Collet C,Xaplanteris P,Zimmermann FM,Toth GG,Tonino PAL,Pijls NHJ,Colaiori I,Di Gioia G,Barbato E,Jüni P,Fearon WF,De Bruyne B

更新日期：2020-12-15 00:00:00

abstract：BACKGROUND:Heart failure is a highly prevalent cardiovascular complication among patients receiving long-term hemodialysis, but the benefits of carvedilol, bisoprolol, and metoprolol controlled release/extended release on the outcomes of these patients remain unclear. In this study, we address the use of these 3 β-bloc...

journal_title：Journal of the American Heart Association

authors： Tang CH,Wang CC,Chen TH,Hong CY,Sue YM

更新日期：2016-01-06 00:00:00

abstract：BACKGROUND:Fatty acids constitute the critical components of cell structure and function, and dysregulation of fatty acid composition may exert diverging vascular effects including proliferation, migration, and differentiation of vascular smooth muscle cells (VSMCs). However, direct evidence for this hypothesis has bee...

journal_title：Journal of the American Heart Association

authors： Sunaga H,Matsui H,Anjo S,Syamsunarno MR,Koitabashi N,Iso T,Matsuzaka T,Shimano H,Yokoyama T,Kurabayashi M

更新日期：2016-11-23 00:00:00

abstract：:Background For individuals with an out-of-hospital cardiac arrest (OHCA), survival may be influenced by the neighborhood in which the arrest occurs. Methods and Results Within the national CARES (Cardiac Arrest Registry to Enhance Survival) registry, we identified 169 502 patients with OHCA from 2013 to 2017. On the b...

journal_title：Journal of the American Heart Association

authors： Chan PS,McNally B,Vellano K,Tang Y,Spertus JA

更新日期：2020-02-18 00:00:00

abstract：:Background Pharmacists-led medication reviews (MRs) are claimed to be effective for the control of cardiovascular diseases; however, the evidence in the literature is conflicting. The main objective of this meta-analysis was to analyze the impact of pharmacist-led MRs on cardiovascular disease risk factors overall and...

journal_title：Journal of the American Heart Association

authors： Martínez-Mardones F,Fernandez-Llimos F,Benrimoj SI,Ahumada-Canale A,Plaza-Plaza JC,S Tonin F,Garcia-Cardenas V

更新日期：2019-11-19 00:00:00

abstract：BACKGROUND:The natural history of coronary artery aneurysms (CAA) after intravenous immunoglobulin (IVIG) treatment in the United States is not well described. We describe the natural history of CAA in US Kawasaki disease (KD) patients and identify factors associated with major adverse cardiac events (MACE) and CAA reg...

journal_title：Journal of the American Heart Association

authors： Friedman KG,Gauvreau K,Hamaoka-Okamoto A,Tang A,Berry E,Tremoulet AH,Mahavadi VS,Baker A,deFerranti SD,Fulton DR,Burns JC,Newburger JW

更新日期：2016-09-15 00:00:00

abstract：BACKGROUND:The structure of the aorta is considered to influence exercise systolic blood pressure (SBP) response, which, in turn, might impact upon adverse outcomes. The current study sought to investigate the relationship of aortic calcification and exercise SBP with adverse outcomes among elderly individuals. METHOD...

journal_title：Journal of the American Heart Association

authors： Cho IJ,Chang HJ,Cho I,Heo R,Lee SE,Shim CY,Hong GR,Chung N

更新日期：2016-04-22 00:00:00

abstract：BACKGROUND:Platelet activation can lead to enhanced oxidative stress, inflammatory response, and endothelial dysfunction. To quantify the effects of platelet inhibition on endothelial function, we assessed platelet activity of healthy persons before and after clopidogrel administration and evaluated its effects on endo...

journal_title：Journal of the American Heart Association

authors： Salimi S,Lewis JP,Yerges-Armstrong LM,Mitchell BD,Saeed F,O'Connell JR,Perry JA,Ryan KA,Shuldiner AR,Parsa A

更新日期：2016-10-31 00:00:00

abstract：:Background Exposure to chronic psychosocial stress is a risk factor for atherosclerosis-based cardiovascular disease. We previously demonstrated the increased expressions of cathepsin S (CatS) in atherosclerotic lesions. Whether CatS participates directly in stress-related neointimal hyperplasia has been unknown. Meth...

journal_title：Journal of the American Heart Association

authors： Wang H,Meng X,Piao L,Inoue A,Xu W,Yu C,Nakamura K,Hu L,Sasaki T,Wu H,Unno K,Umegaki H,Murohara T,Shi GP,Kuzuya M,Cheng XW

更新日期：2019-07-16 00:00:00

abstract：BACKGROUND:No data are available on the long-term performance of ultrathin strut biodegradable polymer sirolimus-eluting stents (BP-SES). We reported 2-year clinical outcomes of the BIOSCIENCE (Ultrathin Strut Biodegradable Polymer Sirolimus-Eluting Stent Versus Durable Polymer Everolimus-Eluting Stent for Percutaneous...

journal_title：Journal of the American Heart Association

authors： Zbinden R,Piccolo R,Heg D,Roffi M,Kurz DJ,Muller O,Vuilliomenet A,Cook S,Weilenmann D,Kaiser C,Jamshidi P,Franzone A,Eberli F,Jüni P,Windecker S,Pilgrim T

更新日期：2016-03-15 00:00:00

abstract：:We, the Editors of the Journal of the American Heart Association, sincerely regret the publication of the article "Diversity, Inclusion, and Equity: Evolution of Race and Ethnicity Considerations for the Cardiology Workforce in the United States of America From 1969 to 2019".1 We are aware that the publication of this...

journal_title：Journal of the American Heart Association

authors： London B,Ahmad F,Eitzman DT,Gupta AK,Jneid H,Peterson P,Remme CA,Rice K,Schelbert EB,Simon MA,Sullivan LM,Weinberg JM

更新日期：2020-10-20 00:00:00

abstract：BACKGROUND:To address the lack of knowledge regarding the long-term risk of intracranial hemorrhage (ICH) after acute myocardial infarction (AMI), the aims of this study were to: (1) investigate the incidence, time trends, and predictors of ICH in a large population within 1 year of discharge after AMI; (2) investigate...

journal_title：Journal of the American Heart Association

authors： Graipe A,Binsell-Gerdin E,Söderström L,Mooe T

更新日期：2015-12-11 00:00:00

abstract：:Background Duchenne muscular dystrophy (DMD) is a neuromuscular disorder caused by mutations within the dystrophin gene. DMD is characterized by progressive skeletal muscle degeneration and atrophy and progressive cardiomyopathy. It has been observed the severity of cardiomyopathy varies in patients with DMD. Methods ...

journal_title：Journal of the American Heart Association

authors： Jiang X,Shao Y,Araj FG,Amin AA,Greenberg BM,Drazner MH,Xing C,Mammen PPA

更新日期：2020-10-20 00:00:00