Effects of Preoperative Statin on Acute Kidney Injury After Off-Pump Coronary Artery Bypass Grafting.

abstract：BACKGROUND:Epidemiology of myocarditis in childhood is largely unknown. Men are known to have a higher incidence of myocarditis than women in adults aged <50 years, but whether this is true by sex in pediatric age groups is unknown. We set out to study the occurrence and potential sex differences of myocarditis in a ge...

journal_title：Journal of the American Heart Association

authors： Arola A,Pikkarainen E,Sipilä JO,Pykäri J,Rautava P,Kytö V

更新日期：2017-11-18 00:00:00

abstract：:Background Coronary artery disease remains a major cause of death despite better outcomes of ST-segment-elevation myocardial infarction (STEMI). We aimed to analyze data from the Ruti-STEMI registry of in-hospital, 28-day, and 1-year events in patients with STEMI over the past 3 decades in Catalonia, Spain, to assess ...

journal_title：Journal of the American Heart Association

authors： García-García C,Oliveras T,Serra J,Vila J,Rueda F,Cediel G,Labata C,Ferrer M,Carrillo X,Dégano IR,De Diego O,El Ouaddi N,Montero S,Mauri J,Elosua R,Lupón J,Bayes-Genis A,Ruti‐STEMI Investigators †.

更新日期：2020-10-20 00:00:00

abstract：:Background Atrial fibrillation (AF) has been shown to be associated with an increased risk of dementia as well as Alzheimer disease in observational studies. Whether this association reflects causal association is still unclear. The purpose of this study was to examine the causal association of AF with Alzheimer disea...

journal_title：Journal of the American Heart Association

authors： Pan Y,Wang Y,Wang Y

更新日期：2020-01-21 00:00:00

abstract：:Background Crossover dilutes treatment effect and reduces statistical power of intention-to-treat analysis. We examined incidence and impact on cardiac surgery randomized controlled trial (RCT) outcomes of crossover from experimental to control interventions, or vice versa. Methods and Results MEDLINE, EMBASE, and Coc...

journal_title：Journal of the American Heart Association

authors： Gaudino M,Fremes SE,Ruel M,Di Franco A,Di Mauro M,Chikwe J,Frati G,Girardi LN,Taggart DP,Biondi-Zoccai G

更新日期：2019-11-05 00:00:00

abstract：BACKGROUND:The increased adverse cardiac events in women undergoing coronary artery bypass grafting are multifactorial and may include clinical, psychosocial, and biological factors. Potential contributing biological factors could include vascular hyperreactivity of the internal mammary artery (IMA) to endogenous vasoc...

journal_title：Journal of the American Heart Association

authors： Lamin V,Jaghoori A,Jakobczak R,Stafford I,Heresztyn T,Worthington M,Edwards J,Viana F,Stuklis R,Wilson DP,Beltrame JF

更新日期：2018-07-09 00:00:00

abstract：:Background Spontaneously hypertensive rats of the stroke-prone line (SHR-A3) develop hypertensive renal disease as a result of naturally occurring genetic variation. Our prior work identified a single-nucleotide polymorphism unique to SHR-A3 that results in truncation of the carboxy terminus of STIM1. The SHR-B2 line,...

journal_title：Journal of the American Heart Association

authors： Dhande IS,Zhu Y,Kneedler SC,Joshi AS,Hicks MJ,Wenderfer SE,Braun MC,Doris PA

更新日期：2020-03-03 00:00:00

abstract：BACKGROUND:Atherosclerosis is a chronic inflammatory disorder whose development is inversely correlated with high-density lipoprotein concentration. Current therapies involve pharmaceuticals that significantly elevate plasma high-density lipoprotein cholesterol concentrations. Our studies were conducted to investigate ...

journal_title：Journal of the American Heart Association

authors： Kaul S,Xu H,Zabalawi M,Maruko E,Fulp BE,Bluemn T,Brzoza-Lewis KL,Gerelus M,Weerasekera R,Kallinger R,James R,Zhang YS,Thomas MJ,Sorci-Thomas MG

更新日期：2016-11-07 00:00:00

abstract：BACKGROUND:Timely reperfusion after ST-elevation myocardial infarction (STEMI) improves survival. Guidelines recommend primary percutaneous coronary intervention (PPCI) within 90 minutes of arrival at a PCI-capable hospital. The alternative is fibrinolysis within 30 minutes for those in those for whom timely transfer t...

journal_title：Journal of the American Heart Association

authors： Hira RS,Bhatt DL,Fonarow GC,Heidenreich PA,Ju C,Virani SS,Bozkurt B,Petersen LA,Hernandez AF,Schwamm LH,Eapen ZJ,Albert MA,Liang L,Matsouaka RA,Peterson ED,Jneid H

更新日期：2016-10-06 00:00:00

abstract：BACKGROUND:Hispanic persons represent a heterogeneous and growing population of any race with origins in Mexico, the Caribbean, Central America, South America, or other Spanish-speaking countries. Previous studies have documented variation in cardiovascular risk and outcomes among Hispanic subgroups. Few studies have i...

journal_title：Journal of the American Heart Association

authors： Rodriguez F,Hastings KG,Hu J,Lopez L,Cullen M,Harrington RA,Palaniappan LP

更新日期：2017-12-13 00:00:00

abstract：BACKGROUND:The American Heart Association (AHA) recently developed the Cardiovascular Health Index (CVHI), a health metric consisting of 7 modifiable risk factors. The relationship of the CVHI with preclinical markers, such as carotid intima-media thickness (CIMT) has not been assessed. METHODS:We examined 490 male mo...

journal_title：Journal of the American Heart Association

authors： Kulshreshtha A,Goyal A,Veledar E,McClellan W,Judd S,Eufinger SC,Bremner JD,Goldberg J,Vaccarino V

更新日期：2014-01-02 00:00:00

abstract：:Background Normal-flow, low-gradient severe aortic stenosis (NF-LG-SAS), defined by aortic valve area <1 cm2, mean gradient <40 mm Hg, and indexed stroke volume >35 mL/m2, is the most prevalent form of low-gradient aortic stenosis (AS). However, the true severity of AS and the management of NF-LG-SAS are controversial...

journal_title：Journal of the American Heart Association

authors： Chadha G,Bohbot Y,Rusinaru D,Maréchaux S,Tribouilloy C

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Hospital procedures have been associated with cognitive change in older patients. This study aimed to document the prevalence of mild cognitive impairment in individuals undergoing left heart catheterization (LHC) before the procedure and the incidence of cognitive decline to 3 months afterwards. METHODS AN...

journal_title：Journal of the American Heart Association

authors： Scott DA,Evered L,Maruff P,MacIsaac A,Maher S,Silbert BS

更新日期：2018-03-10 00:00:00

abstract：BACKGROUND:It is uncertain whether sex and race affect thrombogenicity in patients with coronary artery disease. We evaluated the effects of sex and race on thrombogenicity in patients with coronary artery disease treated with aspirin. METHODS AND RESULTS:Patients on aspirin therapy for 1 week or longer with known or ...

journal_title：Journal of the American Heart Association

authors： Lev EI,Bliden KP,Jeong YH,Pandya S,Kang K,Franzese C,Tantry US,Gurbel PA

更新日期：2014-10-20 00:00:00

abstract：:Compared with the extensive data on left-sided infective endocarditis (IE), there is much less published information on the features and management of right-sided IE. Right-sided IE accounts for 5% to 10% of all IE cases, and compared with left-sided IE, it is more often associated with intravenous drug use, intracard...

journal_title：Journal of the American Heart Association

authors： Shmueli H,Thomas F,Flint N,Setia G,Janjic A,Siegel RJ

更新日期：2020-08-04 00:00:00

abstract：BACKGROUND:Diminished growth hormone (GH) is associated with impaired endothelial function and fibrinolysis. GH-releasing hormone is the primary stimulus for GH secretion and a substrate of dipeptidyl peptidase-4. We tested the hypothesis that dipeptidyl peptidase-4 inhibition with sitagliptin increases stimulated GH s...

journal_title：Journal of the American Heart Association

authors： Wilson JR,Brown NJ,Nian H,Yu C,Bidlingmaier M,Devin JK

更新日期：2018-02-25 00:00:00

abstract：BACKGROUND:Family history of coronary heart disease (CHD) as well as genetic predisposition to CHD assessed by a genetic risk score (GRS) are predictors of CHD risk. It is, however, uncertain to what extent these risk predictors are mediated by major metabolic pathways. METHODS AND RESULTS:Total effects of self-report...

journal_title：Journal of the American Heart Association

authors： Fritz J,Shiffman D,Melander O,Tada H,Ulmer H

更新日期：2017-03-20 00:00:00

abstract：:BACKGROUND The development of congenital heart disease (CHD) is multifactorial with genetic and environmental influences. We sought to determine the relationship between socioeconomic and environmental factors with the incidence of CHD among live-born infants in California and to determine whether maternal comorbiditi...

journal_title：Journal of the American Heart Association

authors： Peyvandi S,Baer RJ,Chambers CD,Norton ME,Rajagopal S,Ryckman KK,Moon-Grady A,Jelliffe-Pawlowski LL,Steurer MA

更新日期：2020-04-21 00:00:00

abstract：:Background Recent evidence suggests that racial/ethnic differences in circulating levels of free or bioavailable 25-hydroxy vitamin D (25[ OH ]D) rather than total 25( OH )D may explain apparent racial disparities in cardiovascular disease ( CVD ). We prospectively examined black-white differences in the associations ...

journal_title：Journal of the American Heart Association

authors： Zhang X,Tu W,Manson JE,Tinker L,Liu S,Cauley JA,Qi L,Mouton C,Martin LW,Hou L,Song Y

更新日期：2019-02-19 00:00:00

abstract：:Background Recent studies suggest that mavacamten (Myk461), a small myosin-binding molecule, decreases hypercontractility in myocardium expressing hypertrophic cardiomyopathy-causing missense mutations in myosin heavy chain. However, the predominant feature of most mutations in cardiac myosin binding protein-C ( cMyBP...

journal_title：Journal of the American Heart Association

authors： Mamidi R,Li J,Doh CY,Verma S,Stelzer JE

更新日期：2018-09-04 00:00:00

abstract：BACKGROUND:The ventricular fibrillation amplitude spectral area (AMSA) predicts whether an electrical shock could terminate ventricular fibrillation and prompt return of spontaneous circulation. We hypothesized that AMSA can guide more precise timing for effective shock delivery during cardiopulmonary resuscitation. M...

journal_title：Journal of the American Heart Association

authors： Aiello S,Perez M,Cogan C,Baetiong A,Miller SA,Radhakrishnan J,Kaufman CL,Gazmuri RJ

更新日期：2017-11-04 00:00:00

abstract：:Background Autonomic dysregulation represents a hallmark of coronary artery disease (CAD). Therefore, we investigated the effects of exercise-based cardiac rehabilitation (CR) on autonomic function and neuro-cardiovascular stress reactivity in CAD patients. Methods and Results Twenty-two CAD patients (4 women; 62±8 ye...

journal_title：Journal of the American Heart Association

authors： Badrov MB,Wood KN,Lalande S,Sawicki CP,Borrell LJ,Barron CC,Vording JL,Fleischhauer A,Suskin N,McGowan CL,Shoemaker JK

更新日期：2019-09-03 00:00:00

abstract：BACKGROUND:Among the growing numbers of patients with heart failure, up to one half have heart failure with preserved ejection fraction (HFpEF). The lack of effective treatments for HFpEF is a substantial and escalating unmet clinical need-and the lack of HFpEF-specific animal models represents a major preclinical barr...

journal_title：Journal of the American Heart Association

authors： Curl CL,Danes VR,Bell JR,Raaijmakers AJA,Ip WTK,Chandramouli C,Harding TW,Porrello ER,Erickson JR,Charchar FJ,Kompa AR,Edgley AJ,Crossman DJ,Soeller C,Mellor KM,Kalman JM,Harrap SB,Delbridge LMD

更新日期：2018-06-01 00:00:00

abstract：:Background The ODYSSEY OUTCOMES (Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome) trial demonstrated that alirocumab reduced major cardiovascular events. However, because of the hierarchical testing strategy used for the multiple outcomes examined, the observed reduction in all-cause mortality was...

journal_title：Journal of the American Heart Association

authors： Labos C,Brophy JM,Sniderman A,Thanassoulis G

更新日期：2019-10-15 00:00:00

abstract：:Background Meta-analyses are expected to follow a standardized process, and thus, they have become highly formulaic, although there is little evidence that such regimentation yields high-quality results. Methods and Results This article describes the results of a critical examination of 14 published meta-analyses of c...

journal_title：Journal of the American Heart Association

authors： Packer M

更新日期：2019-11-05 00:00:00

abstract：BACKGROUND:Relevant clinical studies have been small and have not convincingly demonstrated whether the perioperative initiation of beta-blockers should be considered in patients with diabetes mellitus undergoing noncardiac surgery. METHODS AND RESULTS:In this nationwide propensity score-matched study, we included pat...

journal_title：Journal of the American Heart Association

authors： Chen RJ,Chu H,Tsai LW

更新日期：2017-01-10 00:00:00

abstract：BACKGROUND:Patients receiving oral anticoagulation in addition to dual-antiplatelet therapy are known to be at high risk for bleeding events; thus, the selection of a drug-eluting stent (DES) versus a bare metal stent (BMS) can have important implications for patients with atrial fibrillation (AF) presenting with acute...

journal_title：Journal of the American Heart Association

authors： Vora AN,Wang TY,Li S,Chiswell K,Hess C,Lopes RD,Rao SV,Peterson ED

更新日期：2017-08-21 00:00:00

abstract：BACKGROUND:In-stent hyperplasia (ISH) may develop in regions of low endothelial shear stress (ESS), but the relationship between the magnitude of low ESS, the extent of ISH, and subsequent clinical events has not been investigated. METHODS AND RESULTS:We assessed the association of poststent ESS with neointimal ISH an...

journal_title：Journal of the American Heart Association

authors： Shishido K,Antoniadis AP,Takahashi S,Tsuda M,Mizuno S,Andreou I,Papafaklis MI,Coskun AU,O'Brien C,Feldman CL,Saito S,Edelman ER,Stone PH

更新日期：2016-09-14 00:00:00

abstract：:See Article Shah et al. ...

journal_title：Journal of the American Heart Association

authors： Winniford MD

更新日期：2019-06-04 00:00:00

abstract：:Background The purpose of this study was to determine whether the presence of antegrade blood flow was related to stroke subtype in patients with acute intracranial large artery occlusion. Methods and Results The prospectively collected data for consecutive patients who had occlusion of the unilateral M1 segment of th...

journal_title：Journal of the American Heart Association

authors： Zhang M,Chen Z,Xu J,Gong X,Shi F,Lou M

更新日期：2020-10-20 00:00:00

abstract：:Background Global fractional flow reserve (FFR) (ie, the sum of the FFR values in the 3 major coronary arteries) is a physiologic correlate of global atherosclerotic burden. The objective of the present study was to investigate the value of global FFR in predicting long-term clinical outcome of patients with stable co...

journal_title：Journal of the American Heart Association

authors： Fournier S,Collet C,Xaplanteris P,Zimmermann FM,Toth GG,Tonino PAL,Pijls NHJ,Colaiori I,Di Gioia G,Barbato E,Jüni P,Fearon WF,De Bruyne B

更新日期：2020-12-15 00:00:00