Implantable Ventricular Assist Device Use and Outcomes in People With End-Stage Renal Disease.

abstract：:Background The aim of the present study was to investigate the efficacy and safety of antiplatelet (aspirin plus cilostazol) dual therapy for patients with noncardioembolic stroke within 48 hours of symptom onset. Methods and Results The ADS (Acute Aspirin Plus Cilostazol Dual Therapy for Non-Cardiogenic Stroke Patien...

journal_title：Journal of the American Heart Association

authors： Aoki J,Iguchi Y,Urabe T,Yamagami H,Todo K,Fujimoto S,Idomari K,Kaneko N,Iwanaga T,Terasaki T,Tanaka R,Yamamoto N,Tsujino A,Nomura K,Abe K,Uno M,Okada Y,Matsuoka H,Yamagata S,Yamamoto Y,Yonehara T,Inoue T,Yagit

更新日期：2019-08-06 00:00:00

abstract：:Background Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiomyopathy. Current guidelines endorse management in expert centers, but patient socioeconomic status can affect access to specialty care. The effect of socioeconomic status and specialty care access on HCM outcomes has not been examined. Me...

journal_title：Journal of the American Heart Association

authors： Thomas A,Papoutsidakis N,Spatz E,Testani J,Soucier R,Chou J,Ahmad T,Darr U,Hu X,Li F,Chen ME,Bellumkonda L,Sumathipala A,Jacoby D

更新日期：2020-02-04 00:00:00

abstract：BACKGROUND:Cardiac mesenchymal cell (CMC) administration improves cardiac function in animal models of heart failure. Although the precise mechanisms remain unclear, transdifferentiation and paracrine signaling are suggested to underlie their cardiac reparative effects. We have shown that histone deacetylase 1 (HDAC1) ...

journal_title：Journal of the American Heart Association

authors： Moore JB 4th,Zhao J,Fischer AG,Keith MCL,Hagan D,Wysoczynski M,Bolli R

更新日期：2017-07-05 00:00:00

abstract：:Compared with the extensive data on left-sided infective endocarditis (IE), there is much less published information on the features and management of right-sided IE. Right-sided IE accounts for 5% to 10% of all IE cases, and compared with left-sided IE, it is more often associated with intravenous drug use, intracard...

journal_title：Journal of the American Heart Association

authors： Shmueli H,Thomas F,Flint N,Setia G,Janjic A,Siegel RJ

更新日期：2020-08-04 00:00:00

abstract：BACKGROUND:Higher circulatory corin in patients with cardiac diseases is associated with improved cardiovascular outcomes, and chronic cardiac dysfunction is a well-known cause of progressive renal dysfunction. This study aimed to determine the role of serum corin in predicting short-term and long-term renal outcomes a...

journal_title：Journal of the American Heart Association

authors： Yang SF,Chou RH,Li SY,Huang SS,Huang PH

更新日期：2018-05-04 00:00:00

abstract：BACKGROUND:Cardiovascular clinical trials depend on patient enrollment. Enrollment rates appear inadequate, but little is known about how frequently patients accept or decline offers of enrollment. The objective of this study was to assess trends and predictors of patient acceptance of offers to enroll in clinical tria...

journal_title：Journal of the American Heart Association

authors： Kerkhoff LA,Butler J,Kelkar AA,Shore S,Speight CD,Wall LK,Dickert NW

更新日期：2016-06-17 00:00:00

abstract：BACKGROUND:Contemporary rates of oral anticoagulant (OAC) therapy and associated outcomes among patients undergoing percutaneous coronary intervention (PCI) have been poorly described. METHODS AND RESULTS:Using data from an integrated health care system from 2009 to 2014, we identified patients on OACs within 30 days ...

journal_title：Journal of the American Heart Association

authors： Secemsky EA,Butala NM,Kartoun U,Mahmood S,Wasfy JH,Kennedy KF,Shaw SY,Yeh RW

更新日期：2016-10-17 00:00:00

abstract：:Background This study was performed to characterize the metabolic, functional, and structural cardiac changes in a canine model of radiation-induced heart disease by serial in vivo imaging and ex vivo analyses. Methods and Results Thirty-six dogs were randomly assigned to control or irradiated groups at 3 time points ...

journal_title：Journal of the American Heart Association

authors： Yan R,Li X,Song J,Guo M,Cai H,Wu Z,Wu P,Li L,Yang M,Wang Y,Li S

更新日期：2020-09-15 00:00:00

abstract：:Background NT-proBNP (N-terminal pro-B-type natriuretic peptide) improves the discriminatory ability of risk-prediction models in type 2 diabetes mellitus (T2DM) but is not yet used in clinical practice. We assessed the discriminatory strength of NT-proBNP by itself for death and cardiovascular events in high-risk pat...

journal_title：Journal of the American Heart Association

authors： Malachias MVB,Jhund PS,Claggett BL,Wijkman MO,Bentley-Lewis R,Chaturvedi N,Desai AS,Haffner SM,Parving HH,Prescott MF,Solomon SD,De Zeeuw D,McMurray JJV,Pfeffer MA

更新日期：2020-10-20 00:00:00

abstract：:Background The overall goal of this longitudinal study was to determine if the Black population has decreased myocardial function, which has the potential to lead to the early development of congestive heart failure, compared with the White population. Methods and Results A total of 673 subjects were evaluated over a ...

journal_title：Journal of the American Heart Association

authors： Kapuku G,Howie M,Ghosh S,Doshi V,Bykhovsky M,Ange B,Halbert JD,Robinson V,Bagi Z,Harshfield G,George V

更新日期：2021-01-18 00:00:00

abstract：BACKGROUND:The renin-angiotensin system has a pivotal role in the pathophysiology of visceral obesity. Angiotensin II type 1 receptor (AT1R) is a major player in the signal transduction of the renin-angiotensin system, and the overactivation of this signaling contributes to the progression of visceral obesity. We have ...

journal_title：Journal of the American Heart Association

authors： Azushima K,Ohki K,Wakui H,Uneda K,Haku S,Kobayashi R,Haruhara K,Kinguchi S,Matsuda M,Maeda A,Toya Y,Yamashita A,Umemura S,Tamura K

更新日期：2017-03-06 00:00:00

abstract：:Background Pregnancy increases the risk of acute myocardial infarction (AMI). The purpose of this study was to examine timing and risk factors for AMI in pregnancy and poor outcome. Methods and Results National Inpatient Sample (2003-2015) was screened in pregnancy, labor and delivery, and postpartum. There were 11 29...

journal_title：Journal of the American Heart Association

authors： Balgobin CA,Zhang X,Lima FV,Avila C,Parikh PB,Yang J,Stergiopoulos K

更新日期：2020-11-03 00:00:00

abstract：:Background Impaired heart rate variability (HRV) is associated with increased mortality in sinus rhythm. However, HRV has not been systematically assessed in patients with atrial fibrillation (AF). We hypothesized that parameters of HRV may be predictive of cardiovascular death in patients with AF. Methods and Results...

journal_title：Journal of the American Heart Association

authors： Hämmerle P,Eick C,Blum S,Schlageter V,Bauer A,Rizas KD,Eken C,Coslovsky M,Aeschbacher S,Krisai P,Meyre P,Vesin JM,Rodondi N,Moutzouri E,Beer J,Moschovitis G,Kobza R,Di Valentino M,Corino VDA,Laureanti R,Mainardi L

更新日期：2020-08-04 00:00:00

abstract：:Background We aim to generate a line of "universal donor" human induced pluripotent stem cells (hi PSC s) that are nonimmunogenic and, therefore, can be used to derive cell products suitable for allogeneic transplantation. Methods and Results hi PSC s carrying knockout mutations for 2 key components (β2 microglobulin ...

journal_title：Journal of the American Heart Association

authors： Mattapally S,Pawlik KM,Fast VG,Zumaquero E,Lund FE,Randall TD,Townes TM,Zhang J

更新日期：2018-12-04 00:00:00

abstract：BACKGROUND:It is uncertain whether sex and race affect thrombogenicity in patients with coronary artery disease. We evaluated the effects of sex and race on thrombogenicity in patients with coronary artery disease treated with aspirin. METHODS AND RESULTS:Patients on aspirin therapy for 1 week or longer with known or ...

journal_title：Journal of the American Heart Association

authors： Lev EI,Bliden KP,Jeong YH,Pandya S,Kang K,Franzese C,Tantry US,Gurbel PA

更新日期：2014-10-20 00:00:00

abstract：:Background Normal-flow, low-gradient severe aortic stenosis (NF-LG-SAS), defined by aortic valve area <1 cm2, mean gradient <40 mm Hg, and indexed stroke volume >35 mL/m2, is the most prevalent form of low-gradient aortic stenosis (AS). However, the true severity of AS and the management of NF-LG-SAS are controversial...

journal_title：Journal of the American Heart Association

authors： Chadha G,Bohbot Y,Rusinaru D,Maréchaux S,Tribouilloy C

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Gluteofemoral fat mass has been associated with improved cardiovascular disease risk factors. It is not clear if loss of this protective fat during weight loss partially negates the effect of loss of visceral fat. The aim of this study was to examine regional fat loss in a large weight-loss cohort from one c...

journal_title：Journal of the American Heart Association

authors： Clifton PM

更新日期：2018-04-04 00:00:00

abstract：BACKGROUND:Different sleep-disordered breathing (SDB) phenotypes, including coexisting obstructive and central sleep apnea (OSA-CSA), have not yet been characterized in a large sample of patients with heart failure and reduced ejection fraction (HFrEF) receiving guideline-based therapies. Therefore, the aim of the pres...

journal_title：Journal of the American Heart Association

authors： Arzt M,Oldenburg O,Graml A,Erdmann E,Teschler H,Wegscheider K,Suling A,Woehrle H,SchlaHF Investigators.

更新日期：2017-11-29 00:00:00

abstract：BACKGROUND:The 4-variable risk score from University of California, Los Angeles (UCLA) demonstrated superior discrimination in advanced heart failure, compared to established risk scores. However, the model has not been externally validated, and its suitability as a selection tool for heart transplantation (HT) and lef...

journal_title：Journal of the American Heart Association

authors： Sartipy U,Goda A,Mancini DM,Lund LH

更新日期：2014-06-06 00:00:00

abstract：:Background In the 2000s, adults with HIV had a higher risk for atherosclerotic cardiovascular disease (ASCVD) compared with those without HIV. There is uncertainty if this excess risk still exists in the United States given changes in antiretroviral therapies and increased statin use. Methods and Results We compared t...

journal_title：Journal of the American Heart Association

authors： Rosenson RS,Hubbard D,Monda KL,Reading SR,Chen L,Dluzniewski PJ,Burkholder GA,Muntner P,Colantonio LD

更新日期：2020-01-07 00:00:00

abstract：:Background We evaluated a community-engaged stroke preparedness intervention that aimed to increase early hospital arrival and emergency medical services (EMS) utilization among patients with stroke in the South Side of Chicago, Illinois. Methods and Results We compared change in early hospital arrival (<3 hours from ...

journal_title：Journal of the American Heart Association

authors： Prabhakaran S,Richards CT,Kwon S,Wymore E,Song S,Eisenstein A,Brown J,Kandula NR,Mason M,Beckstrom H,Washington KV,Aggarwal NT

更新日期：2020-09-15 00:00:00

abstract：:The use of extracorporeal cardiopulmonary resuscitation (E-CPR) for the treatment of patients with out-of-hospital cardiac arrest who do not respond to conventional cardiopulmonary resuscitation CPR) has increased significantly in the past 10 years, in response to case reports and observational studies reporting encou...

journal_title：Journal of the American Heart Association

authors： Dennis M,Lal S,Forrest P,Nichol A,Lamhaut L,Totaro RJ,Burns B,Sandroni C

更新日期：2020-05-18 00:00:00

abstract：BACKGROUND:Many patients requiring a pacemaker have persistent hypertension with systolic blood pressures above recommended levels. We evaluated a pacemaker-based Programmable Hypertension Control (PHC) therapy that uses a sequence of variably timed shorter and longer atrioventricular intervals. METHODS AND RESULTS:Pa...

journal_title：Journal of the American Heart Association

authors： Neuzil P,Merkely B,Erglis A,Marinskis G,de Groot JR,Schmidinger H,Rodriguez Venegas M,Voskuil M,Sturmberger T,Petru J,Jongejan N,Aichinger J,Kamzola G,Aidietis A,Gellér L,Mraz T,Osztheimer I,Mika Y,Evans S,Burkhoff

更新日期：2017-12-23 00:00:00

abstract：:Background Isotemporal substitution examines the effect on health outcomes of replacing sedentary time with light-intensity physical activity or moderate-to-vigorous intensity physical activity; however, existing studies are limited by cross-sectional study designs. Methods and Results Participants were 1922 adults fr...

journal_title：Journal of the American Heart Association

authors： Whitaker KM,Pettee Gabriel K,Buman MP,Pereira MA,Jacobs DR Jr,Reis JP,Gibbs BB,Carnethon MR,Staudenmayer J,Sidney S,Sternfeld B

更新日期：2019-01-08 00:00:00

abstract：:Background The digital transformation of medical data provides opportunities to perform digital population health surveillance and identify people inadequately managed in usual care. We leveraged the electronic health records of a large health system to identify patients with markedly elevated blood pressure and chara...

journal_title：Journal of the American Heart Association

authors： Lu Y,Huang C,Mahajan S,Schulz WL,Nasir K,Spatz ES,Krumholz HM

更新日期：2020-04-07 00:00:00

abstract：BACKGROUND:Patients with heart failure with preserved ejection fraction (HFpEF) exhibit a range of cardiovascular phenotypic profiles modified by several common comorbidities. In particular, patients with HFpEF tend to be older; however, it is unclear whether the effects of cardiovascular aging per se modify the expres...

journal_title：Journal of the American Heart Association

authors： Nanayakkara S,Haykowsky M,Mariani J,Van Empel V,Maeder MT,Vizi D,Kaye DM

更新日期：2017-09-22 00:00:00

abstract：:Background Reduced miR-133a was previously found to be associated with thoracic aortic ( TA ) dilation, as seen in aneurysm disease. Because wall tension increases with vessel diameter (Law of Laplace), this study tested the hypothesis that elevated tension led to the reduction of miR-133a in the TA . Methods and Resu...

journal_title：Journal of the American Heart Association

authors： Akerman AW,Blanding WM,Stroud RE,Nadeau EK,Mukherjee R,Ruddy JM,Zile MR,Ikonomidis JS,Jones JA

更新日期：2019-01-08 00:00:00

abstract：:Background Some, but not all, studies report associations between shift work and hypertension, suggesting that particular subgroups may be at risk. We examined moderating effects of sleep duration and circadian preference on the relationship between shift work and new blood pressure (BP) medicine use at follow-up. Met...

journal_title：Journal of the American Heart Association

authors： Riegel B,Daus M,Lozano AJ,Malone SK,Patterson F,Hanlon AL

更新日期：2019-10-15 00:00:00

abstract：BACKGROUND:Kawasaki disease (KD) is a pediatric vasculitis with coronary artery aneurysm (CAA) as a major complication. Controversy exists about cardiovascular risk later in life. The aim of our study was to evaluate whether KD patients are at increased risk, as assessed by carotid intima-media thickness (cIMT). METHO...

journal_title：Journal of the American Heart Association

authors： Dietz SM,Tacke CE,de Groot E,Kuipers IM,Hutten BA,Kuijpers TW,Dutch Kawasaki Study Groupten BergeMaartjeBiezeveldMaarten H.BruijnMartijnDelemarreLuçan C.DolmanKoert M.FilippiniLuc H.P.M.HendriksTomMaingay‐VisserDianne A.P.G.F.NoordzijJeroen

更新日期：2016-07-05 00:00:00

abstract：BACKGROUND:Microparticles (MPs) are circulating membrane particles of less than a micrometer in diameter shed from endothelial and blood cells. Recent literature suggests that MPs are not just functionally inert cell debris but may possess biological functions and mediate the communication between vascular cells. As a ...

journal_title：Journal of the American Heart Association

authors： Horn P,Cortese-Krott MM,Amabile N,Hundsdörfer C,Kröncke KD,Kelm M,Heiss C

更新日期：2012-12-31 00:00:00