Systematic Review and Meta-Analysis of Medication Reviews Conducted by Pharmacists on Cardiovascular Diseases Risk Factors in Ambulatory Care.

abstract：:Background Prevalence of peripheral artery disease ( PAD ) is significantly higher among blacks as compared with non-Hispanic whites, but the role of cigarette smoking in PAD is understudied in blacks. We aimed to evaluate the relationship between cigarette smoking and PAD in blacks in the (JHS) Jackson Heart Study. M...

journal_title：Journal of the American Heart Association

authors： Clark D 3rd,Cain LR,Blaha MJ,DeFilippis AP,Mentz RJ,Kamimura D,White WB,Butler KR,Robertson RM,Bhatnagar A,Butler J,Correa A,Benjamin EJ,Hall ME

更新日期：2019-02-05 00:00:00

abstract：BACKGROUND:Recent studies using stress-rest perfusion cardiovascular magnetic resonance (CMR) demonstrated a close correlation between myocardial ischemia and reduced fractional flow reserve (FFR). However, its diagnostic concordance may be reduced in patients with multivessel disease. We sought to evaluate the concord...

journal_title：Journal of the American Heart Association

authors： Nakamori S,Sakuma H,Dohi K,Ishida M,Tanigawa T,Yamada A,Takase S,Nakajima H,Sawai T,Masuda J,Nagata M,Ichikawa Y,Kitagawa K,Fujii E,Yamada N,Ito M

更新日期：2018-01-26 00:00:00

abstract：BACKGROUND:Atherosclerosis is a chronic inflammatory disorder whose development is inversely correlated with high-density lipoprotein concentration. Current therapies involve pharmaceuticals that significantly elevate plasma high-density lipoprotein cholesterol concentrations. Our studies were conducted to investigate ...

journal_title：Journal of the American Heart Association

authors： Kaul S,Xu H,Zabalawi M,Maruko E,Fulp BE,Bluemn T,Brzoza-Lewis KL,Gerelus M,Weerasekera R,Kallinger R,James R,Zhang YS,Thomas MJ,Sorci-Thomas MG

更新日期：2016-11-07 00:00:00

abstract：BACKGROUND:Oxidative stress is implicated in the etiology of coronary heart disease (CHD). New measures to capture oxidative stress are warranted. Fluorescent oxidation products (FlOPs) can be measured in plasma and have been shown to reflect levels of oxidative stress and to predict risk of CHD in men over 6 years of ...

journal_title：Journal of the American Heart Association

authors： Jensen MK,Wang Y,Rimm EB,Townsend MK,Willett W,Wu T

更新日期：2013-10-08 00:00:00

abstract：BACKGROUND:Excess accumulation of abdominal subcutaneous (SAT) and visceral adipose tissue (VAT) is associated with adverse levels of adipokines and cardiovascular disease risk. Whether fat quality is associated with adipokines has not been firmly established. This study examined the association between abdominal SAT a...

journal_title：Journal of the American Heart Association

authors： Lee JJ,Pedley A,Hoffmann U,Massaro JM,Keaney JF Jr,Vasan RS,Fox CS

更新日期：2016-02-29 00:00:00

abstract：:Background In the 2000s, adults with HIV had a higher risk for atherosclerotic cardiovascular disease (ASCVD) compared with those without HIV. There is uncertainty if this excess risk still exists in the United States given changes in antiretroviral therapies and increased statin use. Methods and Results We compared t...

journal_title：Journal of the American Heart Association

authors： Rosenson RS,Hubbard D,Monda KL,Reading SR,Chen L,Dluzniewski PJ,Burkholder GA,Muntner P,Colantonio LD

更新日期：2020-01-07 00:00:00

abstract：:Background We evaluated a community-engaged stroke preparedness intervention that aimed to increase early hospital arrival and emergency medical services (EMS) utilization among patients with stroke in the South Side of Chicago, Illinois. Methods and Results We compared change in early hospital arrival (<3 hours from ...

journal_title：Journal of the American Heart Association

authors： Prabhakaran S,Richards CT,Kwon S,Wymore E,Song S,Eisenstein A,Brown J,Kandula NR,Mason M,Beckstrom H,Washington KV,Aggarwal NT

更新日期：2020-09-15 00:00:00

abstract：BACKGROUND:A high consumption of omega-3 long-chain polyunsaturated fatty acids, and particularly docosahexaenoic acid (DHA), has been suggested to reduce the risk of cardiovascular disease (CVD). However, while DHA supplementation may have benefits for secondary prevention, few studies have investigated the role of DH...

journal_title：Journal of the American Heart Association

authors： Singhal A,Lanigan J,Storry C,Low S,Birbara T,Lucas A,Deanfield J

更新日期：2013-07-01 00:00:00

abstract：:Background Meta-analyses are expected to follow a standardized process, and thus, they have become highly formulaic, although there is little evidence that such regimentation yields high-quality results. Methods and Results This article describes the results of a critical examination of 14 published meta-analyses of c...

journal_title：Journal of the American Heart Association

authors： Packer M

更新日期：2019-11-05 00:00:00

abstract：:Background Cardiovascular disease incidence, prevalence, morbidity, and mortality have declined in the past several decades; however, disparities persist among subsets of the population. Notably, blacks have not experienced the same improvements on the whole as whites. Furthermore, frequent reports of relatively poore...

journal_title：Journal of the American Heart Association

authors： Islam SJ,Kim JH,Topel M,Liu C,Ko YA,Mujahid MS,Sims M,Mubasher M,Ejaz K,Morgan-Billingslea J,Jones K,Waller EK,Jones D,Uppal K,Dunbar SB,Pemu P,Vaccarino V,Searles CD,Baltrus P,Lewis TT,Quyyumi AA,Taylor H

更新日期：2020-05-05 00:00:00

abstract：BACKGROUND:Family history of coronary heart disease (CHD) as well as genetic predisposition to CHD assessed by a genetic risk score (GRS) are predictors of CHD risk. It is, however, uncertain to what extent these risk predictors are mediated by major metabolic pathways. METHODS AND RESULTS:Total effects of self-report...

journal_title：Journal of the American Heart Association

authors： Fritz J,Shiffman D,Melander O,Tada H,Ulmer H

更新日期：2017-03-20 00:00:00

abstract：:Despite numerous advances in the prevention and treatment of atherosclerosis, cardiovascular disease remains a leading cause of morbidity and mortality. Novel and inexpensive interventions that can contribute to the primary and secondary prevention of cardiovascular disease are of interest. Numerous studies have repor...

journal_title：Journal of the American Heart Association

authors： Levine GN,Lange RA,Bairey-Merz CN,Davidson RJ,Jamerson K,Mehta PK,Michos ED,Norris K,Ray IB,Saban KL,Shah T,Stein R,Smith SC Jr,American Heart Association Council on Clinical Cardiology; Council on Cardiovascular and Stroke Nur

更新日期：2017-09-28 00:00:00

abstract：:Background Detection of flow reserve ( FR ) by dobutamine stress echocardiography is used for risk stratification in low-gradient aortic stenosis ( AS ). Prognostic significance of dobutamine stress echocardiography in the transcatheter aortic valve replacement era is unclear. We aimed to assess the current relevance ...

journal_title：Journal of the American Heart Association

authors： Sato K,Sankaramangalam K,Kandregula K,Bullen JA,Kapadia SR,Krishnaswamy A,Mick S,Rodriguez LL,Grimm RA,Menon V,Desai MY,Svensson LG,Griffin BP,Popović ZB

更新日期：2019-03-19 00:00:00

abstract：BACKGROUND:Low high-density lipoprotein (HDL) levels are major predictors of cardiovascular (CV) events, even in patients on statin treatment with low-density lipoprotein (LDL) at target. In animal models HDLs protect LDL from oxidation and blunt platelet activation. Our study aimed to examine whether HDL levels are re...

journal_title：Journal of the American Heart Association

authors： Vazzana N,Ganci A,Cefalù AB,Lattanzio S,Noto D,Santoro N,Saggini R,Puccetti L,Averna M,Davì G

更新日期：2013-04-04 00:00:00

abstract：:Background Atrial fibrillation (AF) has been shown to be associated with an increased risk of dementia as well as Alzheimer disease in observational studies. Whether this association reflects causal association is still unclear. The purpose of this study was to examine the causal association of AF with Alzheimer disea...

journal_title：Journal of the American Heart Association

authors： Pan Y,Wang Y,Wang Y

更新日期：2020-01-21 00:00:00

abstract：:Background The current study aims to validate the accuracy of 3-dimensional speckle-tracking echocardiography (3D-STE) in evaluating biventricular functions against the accuracy of cardiac magnetic resonance (CMR) and to explore the comprehensive characteristics and normal values for 3D-biventricular functions in tran...

journal_title：Journal of the American Heart Association

authors： Lv Q,Sun W,Wang J,Wu C,Li H,Shen X,Liang B,Dong N,Li Y,Zhang L,Xie M

更新日期：2020-05-18 00:00:00

abstract：:Background Several lipid-lowering therapies reduce CRP (C-reactive protein) independently of LDL-C (low-density lipoprotein cholesterol) reduction, but the association between CRP parameters and benefits from more-intensive LDL-C lowering is inconclusive. We aimed to determine whether the benefits of more- versus less...

journal_title：Journal of the American Heart Association

authors： Zhang XL,Lan RF,Zhang XW,Xu W,Wang L,Kang LN,Xu B

更新日期：2019-08-20 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea is associated with high blood pressure. The magnitude of blood pressure effects from sleep apnea treatment is unclear. We aimed to determine the effect of mandibular advancement device therapy on ambulatory nighttime and daytime blood pressure in women and men with daytime sleepiness ...

journal_title：Journal of the American Heart Association

authors： Rietz H,Franklin KA,Carlberg B,Sahlin C,Marklund M

更新日期：2018-06-21 00:00:00

abstract：BACKGROUND:Fatty acids constitute the critical components of cell structure and function, and dysregulation of fatty acid composition may exert diverging vascular effects including proliferation, migration, and differentiation of vascular smooth muscle cells (VSMCs). However, direct evidence for this hypothesis has bee...

journal_title：Journal of the American Heart Association

authors： Sunaga H,Matsui H,Anjo S,Syamsunarno MR,Koitabashi N,Iso T,Matsuzaka T,Shimano H,Yokoyama T,Kurabayashi M

更新日期：2016-11-23 00:00:00

abstract：BACKGROUND:Heart failure is a highly prevalent cardiovascular complication among patients receiving long-term hemodialysis, but the benefits of carvedilol, bisoprolol, and metoprolol controlled release/extended release on the outcomes of these patients remain unclear. In this study, we address the use of these 3 β-bloc...

journal_title：Journal of the American Heart Association

authors： Tang CH,Wang CC,Chen TH,Hong CY,Sue YM

更新日期：2016-01-06 00:00:00

abstract：:Background Genetic testing in pediatric primary dilated cardiomyopathy (DCM) patients has identified numerous disease-causing variants, but few studies have evaluated genetic testing outcomes in this population in the context of patient and familial clinical data or assessed the clinical implications of temporal chang...

journal_title：Journal of the American Heart Association

authors： Quiat D,Witkowski L,Zouk H,Daly KP,Roberts AE

更新日期：2020-06-02 00:00:00

abstract：BACKGROUND:Metropolitan versus nonmetropolitan status and area median income may independently affect care for and outcomes of acute coronary syndromes. We sought to determine whether location of care modifies the association among area income, receipt of cardiac catheterization, and mortality following an acute corona...

journal_title：Journal of the American Heart Association

authors： Fabreau GE,Leung AA,Southern DA,James MT,Knudtson ML,Ghali WA,Ayanian JZ

更新日期：2016-02-23 00:00:00

abstract：BACKGROUND:NO bioavailability has not been systematically examined in congenital heart disease (CHD). To assess NO in patients with CHD, we measured nasal NO (nNO) generated by the nasal epithelia, given blood NO is difficult to measure (half-life, <2 ms). Given NO's role in hemodynamic regulation and the association o...

journal_title：Journal of the American Heart Association

authors： Adams PS,Zahid M,Khalifa O,Feingold B,Lo CW

更新日期：2017-12-06 00:00:00

abstract：:Background While high levels of lipids and lipid variability are established risk factors for atherosclerotic cardiovascular disease, their roles in the development of atrial fibrillation (AF) are unclear, with previous studies suggesting a "cholesterol paradox." Methods and Results A nationwide population-based cohor...

journal_title：Journal of the American Heart Association

authors： Lee HJ,Lee SR,Choi EK,Han KD,Oh S

更新日期：2019-12-03 00:00:00

abstract：BACKGROUND:Beta-blockers (BB) are recommended in secondary prevention of acute myocardial infarction (AMI), but adherence to prescription medication is a recognized problem. Most literature on the consequences of poor adherence to prescribed BB is limited by the possibility of "healthy adherer bias" and better-designed...

journal_title：Journal of the American Heart Association

authors： Di Bartolomeo S,Marino M,Guastaroba P,Valent F,De Palma R

更新日期：2015-01-07 00:00:00

abstract：BACKGROUND:Cystathionine γ-lyase, cystathionine β-synthase, and 3-mercaptopyruvate sulfurtransferase are endogenous enzymatic sources of hydrogen sulfide (H2S). Functions of H2S are mediated by several targets including ion channels and signaling proteins. Nuclear factor-erythroid 2-related factor 2 is responsible for ...

journal_title：Journal of the American Heart Association

authors： Islam KN,Polhemus DJ,Donnarumma E,Brewster LP,Lefer DJ

更新日期：2015-05-14 00:00:00

abstract：BACKGROUND:Few studies have evaluated the association between secondhand smoke (SHS) and subclinical cardiovascular disease among ethnically diverse populations. This study assesses the impact of SHS on inflammation and atherosclerosis (carotid intima-media thickness, coronary artery calcification, and peripheral arter...

journal_title：Journal of the American Heart Association

authors： Jones MR,Magid HS,Al-Rifai M,McEvoy JW,Kaufman JD,Hinckley Stukovsky KD,Szklo M,Polak J,Burke GL,Post WS,Blaha MJ,Navas-Acien A

更新日期：2016-12-19 00:00:00

abstract：BACKGROUND:Respiratory muscle weakness contributes to exercise intolerance in patients with heart failure with a preserved ejection fraction (HFpEF)-a condition characterized by multiple comorbidities with few proven treatments. We aimed, therefore, to provide novel insight into the underlying diaphragmatic alterations...

journal_title：Journal of the American Heart Association

authors： Bowen TS,Brauer D,Rolim NPL,Bækkerud FH,Kricke A,Ormbostad Berre AM,Fischer T,Linke A,da Silva GJ,Wisloff U,Adams V

更新日期：2017-10-24 00:00:00

abstract：:Background Global fractional flow reserve (FFR) (ie, the sum of the FFR values in the 3 major coronary arteries) is a physiologic correlate of global atherosclerotic burden. The objective of the present study was to investigate the value of global FFR in predicting long-term clinical outcome of patients with stable co...

journal_title：Journal of the American Heart Association

authors： Fournier S,Collet C,Xaplanteris P,Zimmermann FM,Toth GG,Tonino PAL,Pijls NHJ,Colaiori I,Di Gioia G,Barbato E,Jüni P,Fearon WF,De Bruyne B

更新日期：2020-12-15 00:00:00

abstract：:Background Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiomyopathy. Current guidelines endorse management in expert centers, but patient socioeconomic status can affect access to specialty care. The effect of socioeconomic status and specialty care access on HCM outcomes has not been examined. Me...

journal_title：Journal of the American Heart Association

authors： Thomas A,Papoutsidakis N,Spatz E,Testani J,Soucier R,Chou J,Ahmad T,Darr U,Hu X,Li F,Chen ME,Bellumkonda L,Sumathipala A,Jacoby D

更新日期：2020-02-04 00:00:00