Comparative Effectiveness of Generic Atorvastatin and Lipitor® in Patients Hospitalized with an Acute Coronary Syndrome.

abstract：BACKGROUND:MYBPC3 dysfunctions have been proven to induce dilated cardiomyopathy, hypertrophic cardiomyopathy, and/or left ventricular noncompaction; however, the genotype-phenotype correlation between MYBPC3 and restrictive cardiomyopathy (RCM) has not been established. The newly developed next-generation sequencing m...

journal_title：Journal of the American Heart Association

authors： Wu W,Lu CX,Wang YN,Liu F,Chen W,Liu YT,Han YC,Cao J,Zhang SY,Zhang X

更新日期：2015-07-10 00:00:00

abstract：:Background Patients undergoing lead extraction for infected devices have worse outcomes compared with those with noninfected devices. We assessed predictors of in-hospital mortality and procedure-related major adverse events (MAEs) in a large cohort undergoing lead extraction. Methods and Results Deidentified hospital...

journal_title：Journal of the American Heart Association

authors： Aleong RG,Zipse MM,Tompkins C,Aftab M,Varosy P,Sauer W,Kao D

更新日期：2020-04-07 00:00:00

abstract：BACKGROUND:Regression of left ventricular (LV) hypertrophy (LVH) has been a goal in clinical trials. This study tests the external validity of results of clinical trials on LVH regression using a large registry from a tertiary care center, to identify phenotypes less likely to achieve regression of LVH. METHODS AND RE...

journal_title：Journal of the American Heart Association

authors： Lønnebakken MT,Izzo R,Mancusi C,Gerdts E,Losi MA,Canciello G,Giugliano G,De Luca N,Trimarco B,de Simone G

更新日期：2017-03-08 00:00:00

abstract：BACKGROUND:No data are available on the long-term performance of ultrathin strut biodegradable polymer sirolimus-eluting stents (BP-SES). We reported 2-year clinical outcomes of the BIOSCIENCE (Ultrathin Strut Biodegradable Polymer Sirolimus-Eluting Stent Versus Durable Polymer Everolimus-Eluting Stent for Percutaneous...

journal_title：Journal of the American Heart Association

authors： Zbinden R,Piccolo R,Heg D,Roffi M,Kurz DJ,Muller O,Vuilliomenet A,Cook S,Weilenmann D,Kaiser C,Jamshidi P,Franzone A,Eberli F,Jüni P,Windecker S,Pilgrim T

更新日期：2016-03-15 00:00:00

abstract：BACKGROUND:Obesity is closely associated with various cardiovascular diseases (CVDs). Adipose tissue inflammation and perturbation of adipokine secretion may contribute to the pathogenesis of CVD. This study aimed to evaluate whether the 2 most abundant adipokines, adipocyte-fatty acid binding protein (A-FABP) and adip...

journal_title：Journal of the American Heart Association

authors： Chow WS,Tso AW,Xu A,Yuen MM,Fong CH,Lam TH,Lo SV,Tse HF,Woo YC,Yeung CY,Cheung BM,Lam KS

更新日期：2013-01-15 00:00:00

abstract：:Background The 2017 American College of Cardiology (ACC)/American Heart Association (AHA) guidelines lowered the threshold of blood pressure (BP) for hypertension to 130/80 mm Hg. However, the clinical significance of isolated diastolic hypertension (IDH) according to the cutoff value of the 2017 ACC/AHA guidelines wa...

journal_title：Journal of the American Heart Association

authors： Kaneko H,Itoh H,Yotsumoto H,Kiriyama H,Kamon T,Fujiu K,Morita K,Michihata N,Jo T,Takeda N,Morita H,Yasunaga H,Komuro I

更新日期：2020-10-20 00:00:00

abstract：BACKGROUND:Glycosylated proteins partake in multiple cellular processes including inflammation. We hypothesized that GlycA, a novel biomarker of protein glycan N-acetyl groups, is related to incident cardiovascular disease (CVD), and we compared it with high-sensitivity C-reactive protein (hsCRP). METHODS AND RESULTS:...

journal_title：Journal of the American Heart Association

authors： Akinkuolie AO,Buring JE,Ridker PM,Mora S

更新日期：2014-09-23 00:00:00

abstract：BACKGROUND:Extracellular fluid (ECF) excess is an independent predictor of cardiovascular morbidity in patients undergoing dialysis. This study aimed to investigate the relationship between ECF status, which is affected by renal function, and coronary artery calcification (CAC), which is a marker of cardiovascular dise...

journal_title：Journal of the American Heart Association

authors： Park S,Lee CJ,Jhee JH,Yun HR,Kim H,Jung SY,Kee YK,Yoon CY,Park JT,Kim HC,Han SH,Kang SW,Park S,Yoo TH

更新日期：2018-06-30 00:00:00

abstract：:Background Knowledge is scarce regarding how multimorbidity is associated with therapeutic decisions regarding oral anticoagulants (OACs) in patients with atrial fibrillation. Methods and Results We conducted a cross-sectional study of hospitalized patients with atrial fibrillation using the Get With The Guidelines-At...

journal_title：Journal of the American Heart Association

authors： Dalgaard F,Xu H,Matsouaka RA,Russo AM,Curtis AB,Rasmussen PV,Ruwald MH,Fonarow GC,Lowenstern A,Hansen ML,Pallisgaard JL,Alexander KP,Alexander JH,Lopes RD,Granger CB,Lewis WR,Piccini JP,Al-Khatib SM

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Cryoballoon pulmonary vein isolation (PVI) has emerged as an alternative to radiofrequency PVI for atrial fibrillation (AF). Data are lacking to define the rates and predictors of complications, particularly phrenic nerve injury (PNI). METHODS AND RESULTS:We evaluated a single-center prospective registry of...

journal_title：Journal of the American Heart Association

authors： Guhl EN,Siddoway D,Adelstein E,Bazaz R,Mendenhall GS,Nemec J,Saba S,Schwartzman D,Voigt A,Wang NC,Jain SK

更新日期：2016-07-21 00:00:00

abstract：:Background Circulating proteins are exposed to vascular endothelial layer and influence their functions. Among them, adipsin is a member of the trypsin family of peptidases and is mainly secreted from adipocytes, monocytes, and macrophages, catalyzing the rate-limiting step of the alternative complement pathway. Howev...

journal_title：Journal of the American Heart Association

authors： Ohtsuki T,Satoh K,Shimizu T,Ikeda S,Kikuchi N,Satoh T,Kurosawa R,Nogi M,Sunamura S,Yaoita N,Omura J,Aoki T,Tatebe S,Sugimura K,Takahashi J,Miyata S,Shimokawa H

更新日期：2019-12-03 00:00:00

abstract：BACKGROUND:Light chain amyloidosis (AL) is associated with high mortality, especially in patients with advanced cardiovascular involvement. It is caused by toxicity of misfolded light chain proteins (LC) in vascular, cardiac, and other tissues. There is no treatment to reverse LC tissue toxicity. We tested the hypothes...

journal_title：Journal of the American Heart Association

authors： Franco DA,Truran S,Weissig V,Guzman-Villanueva D,Karamanova N,Senapati S,Burciu C,Ramirez-Alvarado M,Blancas-Mejia LM,Lindsay S,Hari P,Migrino RQ

更新日期：2016-06-13 00:00:00

abstract：:Background The "healthy obese" hypothesis suggests the risks associated with excess adiposity are reduced in those with higher muscle quality (mass/strength). Alternative possibilities include loss of muscle quality as people become unwell (reverse causality) or unmeasured confounding. Methods and Results We conducted...

journal_title：Journal of the American Heart Association

authors： Farmer RE,Mathur R,Schmidt AF,Bhaskaran K,Fatemifar G,Eastwood SV,Finan C,Denaxas S,Smeeth L,Chaturvedi N

更新日期：2019-07-02 00:00:00

abstract：:Background Monocular vision loss, attributed to either central retinal artery occlusion ( CRAO ), branch retinal artery occlusion ( BRAO ), or ocular ischemic syndrome ( OIS ), is thought to be associated with an increased prevalence of cerebral infarcts. However, there is a paucity of data substantiating this. We aim...

journal_title：Journal of the American Heart Association

authors： Avery MB,Magal I,Kherani A,Mitha AP

更新日期：2019-02-05 00:00:00

abstract：:See Article Ramkumar et al. ...

journal_title：Journal of the American Heart Association

authors： Braun JD,Kougias P

更新日期：2019-09-03 00:00:00

abstract：BACKGROUND:Left ventricular noncompaction (LVNC) has since been classified as a primary genetic cardiomyopathy, but the genetic basis is not fully evaluated. The aim of the present study was to identify the genetic spectrum using next-generation sequencing and to evaluate genotype-phenotype correlations in LVNC patient...

journal_title：Journal of the American Heart Association

authors： Wang C,Hata Y,Hirono K,Takasaki A,Ozawa SW,Nakaoka H,Saito K,Miyao N,Okabe M,Ibuki K,Nishida N,Origasa H,Yu X,Bowles NE,Ichida F,for LVNC Study Collaborators.

更新日期：2017-08-30 00:00:00

abstract：:See Article Lee et al. ...

journal_title：Journal of the American Heart Association

authors： Hanna P,Zhu C,Rajendran PS,Shivkumar K

更新日期：2019-05-21 00:00:00

abstract：:Background We evaluated a community-engaged stroke preparedness intervention that aimed to increase early hospital arrival and emergency medical services (EMS) utilization among patients with stroke in the South Side of Chicago, Illinois. Methods and Results We compared change in early hospital arrival (<3 hours from ...

journal_title：Journal of the American Heart Association

authors： Prabhakaran S,Richards CT,Kwon S,Wymore E,Song S,Eisenstein A,Brown J,Kandula NR,Mason M,Beckstrom H,Washington KV,Aggarwal NT

更新日期：2020-09-15 00:00:00

abstract：BACKGROUND:Intracerebral hemorrhage (ICH) carries high risk for short-term mortality. We sought to identify race-specific predictors of mortality in ICH patients. METHODS AND RESULTS:We used 2 databases, the Johns Hopkins clinical stroke database and the Nationwide Inpatient Sample (NIS). We included 226 patients with...

journal_title：Journal of the American Heart Association

authors： Faigle R,Marsh EB,Llinas RH,Urrutia VC,Gottesman RF

更新日期：2016-08-16 00:00:00

abstract：BACKGROUND:Impaired generation and signaling of nitric oxide (NO) contribute substantially to cardiovascular (CV) risk (CVR) associated with hypertension, hyperlipidemia, and diabetes mellitus. In our rapidly aging society, advanced age is, in itself, a consistent and independent CVR factor. Many processes involved in ...

journal_title：Journal of the American Heart Association

authors： Sverdlov AL,Ngo DT,Chan WP,Chirkov YY,Horowitz JD

更新日期：2014-08-18 00:00:00

abstract：BACKGROUND:Coronary heart disease and peripheral arterial disease (PAD) affect different vascular territories. Supplementing baseline findings with assays from stored serum, we compared their 20-year predictors. METHODS AND RESULTS:We randomly recruited 15 737 disease-free men and women aged 30 to 75 years across Scot...

journal_title：Journal of the American Heart Association

authors： Tunstall-Pedoe H,Peters SAE,Woodward M,Struthers AD,Belch JJF

更新日期：2017-09-18 00:00:00

abstract：BACKGROUND:Decreased arterial elasticity is a risk factor for several cardiovascular outcomes. Longitudinal data on the effect of physical activity in youth on adult arterial elasticity are limited. The aim of this study was to determine the long-term effects of physical activity in children and young adults on carotid...

journal_title：Journal of the American Heart Association

authors： Pälve KS,Pahkala K,Magnussen CG,Koivistoinen T,Juonala M,Kähönen M,Lehtimäki T,Rönnemaa T,Viikari JS,Raitakari OT

更新日期：2014-04-22 00:00:00

abstract：:Background In this nationwide study, we used the unique Danish registries to estimate the risk of suicide and deliberate self-harm in patients with congenital heart disease (CHD). Methods and Results We identified all Danish citizens receiving a diagnosis of CHD between 1977 and 2007. As a reference cohort, we randoml...

journal_title：Journal of the American Heart Association

authors： Udholm S,Nyboe C,Lundbye-Christensen S,Nordentoft M,Hjortdal VE

更新日期：2020-05-18 00:00:00

abstract：:Background The interrelationships among the different stages of impaired glucose metabolism, insulin resistance, and hypertension are not fully understood. Methods and Results We investigated the impact of insulin resistance, plasma glucose, and serum immunoreactive insulin levels on hypertension in 19 166 participant...

journal_title：Journal of the American Heart Association

authors： Sasaki N,Ozono R,Higashi Y,Maeda R,Kihara Y

更新日期：2020-04-07 00:00:00

abstract：BACKGROUND:Black race has been shown to be a risk factor for amputation in peripheral artery disease (PAD); however, race has been argued to be a marker for socioeconomic status (SES) rather than true disparity. The aim of this study is to study the impact of race and SES on amputation risk in PAD patients. METHODS AN...

journal_title：Journal of the American Heart Association

authors： Arya S,Binney Z,Khakharia A,Brewster LP,Goodney P,Patzer R,Hockenberry J,Wilson PWF

更新日期：2018-01-12 00:00:00

abstract：BACKGROUND:Current American Heart Association/American College of Cardiology guidelines recommend the GRACE (Global Registry of Acute Coronary Events) and TIMI (Thrombolysis in Myocardial Infarction) scores to assess myocardial infarction (MI) prognosis. Changes in the epidemiological characteristics of MI and the avai...

journal_title：Journal of the American Heart Association

authors： Gerber Y,Weston SA,Enriquez-Sarano M,Jaffe AS,Manemann SM,Jiang R,Roger VL

更新日期：2017-10-20 00:00:00

abstract：:Background Both elemental metals and particulate air pollution have been reported to influence adult blood pressure (BP). The aim of this study is to examine which elemental components of particle mass with diameter ≤2.5 μm (PM2.5) are responsible for previously reported associations between PM2.5 and neonatal BP. Met...

journal_title：Journal of the American Heart Association

authors： Zanobetti A,Coull BA,Luttmann-Gibson H,van Rossem L,Rifas-Shiman SL,Kloog I,Schwartz JD,Oken E,Bobb JF,Koutrakis P,Gold DR

更新日期：2021-01-05 00:00:00

abstract：BACKGROUND:The influence of coronary artery disease (CAD) on clinical and echocardiographic outcomes after transcatheter aortic valve replacement (TAVR) is still controversial. We sought to evaluate the impact of CAD severity as measured by the SYNTAX score (SS) on patients undergoing TAVR. METHODS AND RESULTS:A total...

journal_title：Journal of the American Heart Association

authors： Paradis JM,White JM,Généreux P,Urena M,Doshi D,Nazif T,Hahn R,George I,Khalique O,Harjai K,Lasalle L,Labbé BM,DeLarochellière R,Doyle D,Dumont É,Mohammadi S,Leon MB,Rodés-Cabau J,Kodali S

更新日期：2017-02-20 00:00:00

abstract：BACKGROUND:Besides hypertension, obesity and the metabolic syndrome have recently emerged as risk factors for atrial fibrillation. This study sought to delineate the development of an arrhythmogenic substrate for atrial fibrillation in hypertension with and without concomitant obesity and metabolic syndrome. METHODS A...

journal_title：Journal of the American Heart Association

authors： Hohl M,Lau DH,Müller A,Elliott AD,Linz B,Mahajan R,Hendriks JML,Böhm M,Schotten U,Sanders P,Linz D

更新日期：2017-09-17 00:00:00

abstract：BACKGROUND:Cystathionine γ-lyase, cystathionine β-synthase, and 3-mercaptopyruvate sulfurtransferase are endogenous enzymatic sources of hydrogen sulfide (H2S). Functions of H2S are mediated by several targets including ion channels and signaling proteins. Nuclear factor-erythroid 2-related factor 2 is responsible for ...

journal_title：Journal of the American Heart Association

authors： Islam KN,Polhemus DJ,Donnarumma E,Brewster LP,Lefer DJ

更新日期：2015-05-14 00:00:00