Abstract:
:Sarcopenia is a geriatric syndrome with a significant impact on older patients' quality of life, morbidity and mortality. Despite the new available criteria, its early diagnosis remains difficult, highlighting the necessity of looking for a valid muscle wasting biomarker. Myostatin, a muscle mass negative regulator, is one of the potential candidates. The aim of this work is to point out various factors affecting the potential of myostatin as a biomarker of muscle wasting. Based on the literature review, we can say that recent studies produced conflicting results and revealed a number of potential confounding factors influencing their use in sarcopenia diagnosing. These factors include physiological variables (such as age, sex and physical activity) as well as a variety of disorders (including heart failure, metabolic syndrome, kidney failure and inflammatory diseases) and differences in laboratory measurement methodology. Our conclusion is that although myostatin alone might not prove to be a feasible biomarker, it could become an important part of a recently proposed panel of muscle wasting biomarkers. However, a thorough understanding of the interrelationship of these markers, as well as establishing a valid measurement methodology for myostatin and revising current research data in the light of new criteria of sarcopenia, is needed.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Baczek J,Silkiewicz M,Wojszel ZBdoi
10.3390/nu12082401subject
Has Abstractpub_date
2020-08-11 00:00:00issue
8issn
2072-6643pii
nu12082401journal_volume
12pub_type
杂志文章,评审相关文献
Nutrients文献大全abstract::Pre-sleep whey protein intake has been shown to improve overnight muscle protein synthesis, muscle size and strength, and muscle recovery. Despite a growing interest in alternative protein sources, such as plant-based protein, there is no evidence regarding the efficacy of plant-based proteins consumed pre-sleep. Ther...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12072049
更新日期:2020-07-10 00:00:00
abstract::Life-course diet patterns may impact risk of disease, but little is known about dietary trends with aging. In a retrospective longitudinal analysis we estimated lifetime intake of animal products and adherence to vegetarian dietary patterns among 51,082 Adventist Health Study-2 (AHS-2) subjects using data from a relia...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9101118
更新日期:2017-10-13 00:00:00
abstract::The Mediterranean diet (MD) is recognized as one of the healthiest dietary patterns and has benefits such as improving glycaemic control among patients with type 2 diabetes (T2DM). Our aim is to assess the effectiveness of a multifactorial intervention to improve adherence to the MD, diet quality and biomedical parame...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu11010162
更新日期:2019-01-14 00:00:00
abstract::Obesity is associated with food and eating addiction (FA), but the biobehavioral markers of this condition are poorly understood. To characterize FA, we recruited 18 healthy controls and overweight/obese adults with (n = 31) and without (n = 17) FA (H-C, FAOB, NFAOB, respectively) to assess alpha brain asymmetry at re...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12113563
更新日期:2020-11-20 00:00:00
abstract::Obesity is a significant health problem world-wide, particularly in developed nations. Vitamin D deficiency is pandemic, and has been implicated in a wide variety of disease states. This paper seeks to examine the consistently reported relationship between obesity and low vitamin D concentrations, with reference to th...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu5030949
更新日期:2013-03-20 00:00:00
abstract:BACKGROUND AND AIM:Preliminary evaluation of a wild green oat extract (WGOE) (Neuravena(®) ELFA(®)955, Frutarom, Switzerland) revealed an acute cognitive benefit of supplementation. This study investigated whether regular daily WGOE supplementation would result in sustained cognitive improvements. METHOD:A 12-week ran...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu4050331
更新日期:2012-05-01 00:00:00
abstract::Osteoarthritis (OA) is considered one of the most common joint disorders worldwide and its prevalence is constantly increasing due to the global longevity and changes in eating habits and lifestyle. In this context, the role of gut microbiota (GM) in the pathogenesis of OA is still unclear. Perturbation of GM biodiver...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12020574
更新日期:2020-02-22 00:00:00
abstract::The prevention of iodine deficiency through salt iodization has been recognized as a global success story, and China stands at the forefront of this achievement with one of the most successful programs in the world. High level political commitment, national mandatory legislation, a state-managed edible salt industry a...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu9040361
更新日期:2017-04-05 00:00:00
abstract::Sedentary habits during childhood are associated with adverse health outcomes. The aim of this work was to cluster lifestyle behaviors and metabolic biomarkers to establish different patterns in children. Their physical and sedentary activities were evaluated by accelerometry, and questionnaires that included lifestyl...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12051288
更新日期:2020-05-01 00:00:00
abstract::The circadian rhythm of urinary sodium excretion is related to the diurnal blood pressure regulation (BP) and the nocturnal dipping pattern. The renal sodium excretion expressed as daytime/nighttime ratio impacts BP, but a limited number of studies have investigated this topic to date. In this cross-sectional study, w...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12072013
更新日期:2020-07-07 00:00:00
abstract::Bile acids play an active role in fat metabolism and, in high-fat diets, elevated concentrations of fecal bile acids may be related to an increased risk of colorectal cancer. This study investigated concentrations of fecal and serum bile acids in 36 vegans and 36 omnivores. The reduced rank regression was used to iden...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12010047
更新日期:2019-12-23 00:00:00
abstract::This study was designed to assess the effect of a dairy-based recovery beverage on post-exercise appetite and energy intake in active females. Thirteen active females completed three trials in a crossover design. Participants completed 60 min of cycling at 65% V̇O2peak, before a 120 min recovery period. On completion ...
journal_title:Nutrients
pub_type: 临床试验,杂志文章
doi:10.3390/nu8060355
更新日期:2016-06-08 00:00:00
abstract::A dietary prebiotic is defined as 'a substrate that is selectively utilized by host microorganisms conferring a health benefit'. Although this definition evolved concomitantly with the knowledge and technological developments that accrued in the last twenty years, what qualifies as prebiotic continues to be a matter o...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9121376
更新日期:2017-12-20 00:00:00
abstract::High consumption of fructose and high-fructose corn syrup is related to the development of obesity-associated metabolic diseases, which have become the most relevant diet-induced diseases. However, the influences of a high-fructose diet on gut microbiota are still largely unknown. We therefore examined the effect of s...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12113444
更新日期:2020-11-10 00:00:00
abstract::Postprandial hyperglycemia interferes with vascular reactivity and is a strong predictor of cardiovascular disease. Macronutrient preloads reduce postprandial hyperglycemia in subjects with impaired glucose tolerance (IGT) or type 2 diabetes (T2D), but the effect on endothelial function is unknown. Therefore, we exami...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12072053
更新日期:2020-07-10 00:00:00
abstract::The Special Issue "Food Choice and Nutrition" deals with the relationship between the food choices of different population groups or consumer segments and its impact on the nutritional status, improvement of dietary quality, food and nutrition-related behaviour, food preferences, taste education, sensory characteristi...
journal_title:Nutrients
pub_type: 社论
doi:10.3390/nu12020502
更新日期:2020-02-16 00:00:00
abstract::As the demand for food increases with exponential growth in the world population, it is imperative that we understand how to make livestock production as efficient as possible in the face of decreasing available natural resources. Moreover, it is important that livestock are able to meet their metabolic demands and su...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu7053497
更新日期:2015-05-13 00:00:00
abstract::Objectives: To evaluate in patients admitted for stroke: (1) The frequency of hyperglycaemia associated with enteral nutrition (EN). (2) The risk of morbidity and mortality associated with the development of this type of hyperglycaemia. METHODS:A longitudinal observational study was conducted in 115 non-diabetic pati...
journal_title:Nutrients
pub_type:
doi:10.3390/nu11050996
更新日期:2019-04-30 00:00:00
abstract:BACKGROUND:Inflammatory bowel disease (IBD) patients may be at risk of vitamin B12 and folate insufficiencies, as these micronutrients are absorbed in the small intestine, which is affected by IBD. However, a consensus has not been reached on the association between IBD and serum folate and vitamin B12 concentrations. ...
journal_title:Nutrients
pub_type: 杂志文章,meta分析,评审
doi:10.3390/nu9040382
更新日期:2017-04-13 00:00:00
abstract::The association of dietary cholesterol intake with dyslipidemia and subtypes is controversial. This study aimed to examine the association of dietary cholesterol intake with dyslipidemia and subtypes in Chinese adults. Using data from the China Health and Nutrition Survey (CHNS) in 2015, the present study selected 438...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11122885
更新日期:2019-11-27 00:00:00
abstract::Dietary assessment is important for monitoring and evaluating population intakes. Online tools can reduce the level of participant burden and the time taken to complete records, compared with other methods. The study aimed to field test an online dietary recall tool (Intake24) to test the suitability for collecting di...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10111690
更新日期:2018-11-06 00:00:00
abstract::Susceptibility to develop hypertension may be established during early stages of life that include the intrauterine period, infancy and childhood. We recently showed that blood pressure increased when rats reached adulthood when sucrose was ingested for a short-term critical window from postnatal day 12 to 28 in the r...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11020309
更新日期:2019-02-01 00:00:00
abstract::Breastfeeding is natural and the optimal basis of infant nutrition and development, with many benefits for maternal health. Human milk is a dynamic fluid fulfilling an infant's specific nutritional requirements and guiding the growth, developmental, and physiological processes of the infant. Human milk is considered u...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12071952
更新日期:2020-06-30 00:00:00
abstract::Probiotics possibly affect local and systemic immune reactions and maintain the intestinal immune homeostasis in healthy individuals and patients with diseases such as irritable bowel syndrome (IBS). In this single-center, blinded trial, we enrolled 40 individuals (20 patients with IBS and 20 healthy individuals) whos...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12061706
更新日期:2020-06-07 00:00:00
abstract::We previously performed a 4 week interventional trial that suggested that continuous intake of rosemary extract improves the mood states, fatigue, and cognitive function of working generation healthy adult Japanese men. However, the severity of depression in participants in our previous study was relatively mild. Ther...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12113551
更新日期:2020-11-20 00:00:00
abstract::The objective of this study was to inform consumer-facing dietary guidance by (1) adapting the current University of North Carolina at Chapel Hill (UNC) food processing framework to include a home processing (HP) component and (2) pilot testing the adapted version using a nationally representative sample of foods cons...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12082373
更新日期:2020-08-08 00:00:00
abstract::Dietary flavonoids are vasoactive phytochemicals with promising anti-inflammatory properties. We aimed to assess the associations between baseline intakes of six commonly consumed flavonoid subclasses and 10-year incidence of age-related hearing loss. At baseline, 1691 participants aged 50+ years had information on di...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12113297
更新日期:2020-10-28 00:00:00
abstract::The snacking prevalence, frequency of daily snack consumption, and the contribution of snacks to daily energy intake have substantially increased globally. The aim of this study was to examine the patterns of snack consumption among a representative sample of Canadians aged 2 and older. Nationally representative dieta...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11051152
更新日期:2019-05-23 00:00:00
abstract::Epidemiological studies have provided ambiguous evidence on the association between vitamin E and esophageal cancer risk. To resolve this controversy, we performed this meta-analysis. The literature was searched by using Excerpta Medica Database (EMBASE), PubMed, the Web of Science, and the Cochrane Library from the i...
journal_title:Nutrients
pub_type: 杂志文章,meta分析
doi:10.3390/nu10070801
更新日期:2018-06-21 00:00:00
abstract::The hypothesized effect of vitamin D on C-reactive protein (CRP) has received substantial attention as a potential means to alleviate the risk for cardiovascular disease. However, observational studies have been inconsistent in their reporting of associations between serum 25-hydroxyvitamin D (25(OH)D) and CRP concent...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu8110696
更新日期:2016-11-04 00:00:00