Abstract:
:The hypothesized effect of vitamin D on C-reactive protein (CRP) has received substantial attention as a potential means to alleviate the risk for cardiovascular disease. However, observational studies have been inconsistent in their reporting of associations between serum 25-hydroxyvitamin D (25(OH)D) and CRP concentrations, and trials and meta analyses have been inconsistent in their conclusions regarding the effect of vitamin D supplementation on CRP concentrations. These supplementation trials were mostly conducted among patients with more or less inflammatory complications and did not consider potential distinctive effects by weight status. To further our understanding of the potential influences of vitamin D on CRP, we analyzed longitudinal observations of 6755 participants of a preventative health program. On average, serum 25(OH)D concentrations increased from 88.3 to 121.0 nmol/L and those of CRP decreased from 1.7 to 1.6 mg/L between baseline and follow up. Relative to obese participants without temporal increases in 25(OH)D, those who showed improvements of <25, 25-50, 50-75, and more than 75 nmol/L at follow up were 0.57 (95% confidence interval: 0.37-0.88), 0.54 (0.34-0.85), 0.49 (0.30-0.80), and 0.48 (0.29-0.78) times as likely to have elevated CRP concentrations (≥1 mg/L), respectively. These associations were less pronounced and not statistically significant for normal weight and overweight participants. Herewith, the findings suggest that promotion of adequate serum 25(OH)D concentrations among obese individuals along with healthy lifestyles may alleviate the public health burden associated with cardiovascular disease.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Mastroeni SS,Munasinghe LL,Pham TM,Loehr SA,Ekwaru JP,Mastroeni MF,Veugelers PJdoi
10.3390/nu8110696subject
Has Abstractpub_date
2016-11-04 00:00:00issue
11issn
2072-6643pii
nu8110696journal_volume
8pub_type
杂志文章相关文献
Nutrients文献大全abstract::The purpose of this paper was to conduct a systematic review and a meta-analysis of studies examining the acute effects of caffeine ingestion on measures of rowing performance. Crossover and placebo-controlled experiments that investigated the effects of caffeine ingestion on measures of rowing performance were includ...
journal_title:Nutrients
pub_type: 杂志文章,meta分析
doi:10.3390/nu12020434
更新日期:2020-02-08 00:00:00
abstract::As the population of the United States continues to age, it has become increasingly more important to recognize the food intake and eating habits of older adults. The objective of this study was to describe the food group intake, factors predicting food group intake, and the food choices of community-dwelling Kansans,...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu2121297
更新日期:2010-12-01 00:00:00
abstract::The association between breakfast quality and total diet quality of children and adolescents ((1-17.9 years (n = 1570)) from the National Dietary Survey on the Child and Adolescent Population in Spain (ENALIA) was analyzed. Dietary information was collected using two non-consecutive one-day food diaries (1-10 years ol...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12123772
更新日期:2020-12-08 00:00:00
abstract::Celiac disease (CD) is a chronic immune-mediated disorder, characterized by enhanced paracellular permeability across the intestinal epithelium. The complex system of intercellular junctions, including tight junctions (TJs) and adherens junctions (AJs), seals together the epithelial cells to form a continuous layer. T...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10111698
更新日期:2018-11-07 00:00:00
abstract::Fructose consumption by rodents modulates both hepatic and intestinal lipid metabolism and gluconeogenesis. We have previously demonstrated that in utero exposure to dexamethasone (DEX) interacts with fructose consumption during adult life to exacerbate hepatic steatosis in rats. The aim of this study was to clarify i...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12103062
更新日期:2020-10-07 00:00:00
abstract::Advances in web and mobile technologies have created efficiencies relating to collection, analysis and interpretation of dietary intake data. This study compared the impact of two levels of nutrition support: (1) low personalization, comprising a web-based personalized nutrition feedback report generated using the Aus...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12113334
更新日期:2020-10-29 00:00:00
abstract::In adults, fermentation of high amylose maize starch (HAMS), a resistant starch (RS), has a prebiotic effect. Were such a capacity to exist in infants, intake of RS might programme the gut microbiota during a critical developmental period. This study aimed to determine if infant faecal inocula possess the capacity to ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11061345
更新日期:2019-06-14 00:00:00
abstract::A number of recent trials have demonstrated positive effects of dietary supplementation with the omega-3 polyunsaturated fatty acids (n-3 PUFAs), docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) on measures of cognitive function in healthy young and older adults. One potential mechanism by which EPA, and DHA...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu8020086
更新日期:2016-02-09 00:00:00
abstract:BACKGROUND:Hereditary fructose intolerance (HFI) is a rare genetic disorder of fructose metabolism due to aldolase B enzyme deficiency. Treatment consists of fructose, sorbitol, and sucrose (FSS)-free diet. We explore possible correlations between daily fructose traces intake and liver injury biomarkers on a long-term ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11102397
更新日期:2019-10-07 00:00:00
abstract::In this study, we investigated the beneficial effects of milk biofortified with antioxidants on the health of children. Two experiments were conducted: experiment one evaluated the milk of 24 Jersey dairy cows (450 ± 25 kg of body weight (BW); 60 ± 30 days in milk dry matter intake (DIM)) given different diet treatmen...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu11061218
更新日期:2019-05-29 00:00:00
abstract::Awareness and knowledge of nutrient-dense foods are important for older adults to help them make dietary choices that support a food-first approach to healthy aging. This is especially important since age is a major risk factor for chronic disease and the proportion of older adults in North America is increasing. Bean...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11112680
更新日期:2019-11-05 00:00:00
abstract:BACKGROUND AND AIMS:The study compares the essential amino acid (EAA) composition of different parenteral nutrition (PN) mixtures with whey protein EAA profile and the theoretical daily EAA requirements (set by WHO/FAO/UNU or IAAO method). According to the individual EAA profile, the potential effect of several PN mixt...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10121937
更新日期:2018-12-06 00:00:00
abstract::Malathion (MT) and chlorpyrifos (CPF) are immunotoxic organophosphate pesticides that are used extensively in agriculture worldwide. Dietary polyphenols protect against a variety of toxins. In this study, walnut polyphenol extract (WPE) prevents MT- or CPF-induced toxicity to splenic lymphocytes in vitro. WPE promotes...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12030616
更新日期:2020-02-27 00:00:00
abstract:BACKGROUND:Zinc is an indispensable element, being involved in many biological processes. Correspondingly, insufficient zinc intake in early youth can detrimentally affect the function of a growing body. The aim of this study was to determine zinc content in breast milk among lactating women in Latvia and factors (mate...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10101438
更新日期:2018-10-05 00:00:00
abstract::Vitamin A or retinol which is the natural precursor of several biologically active metabolites can be considered the most multifunctional vitamin in mammals. Its deficiency is currently, along with protein malnutrition, the most serious and common nutritional disorder worldwide. It is necessary for normal embryonic de...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu6114984
更新日期:2014-11-10 00:00:00
abstract::The main objective of the study was to investigate the effect of MID during late pregnancy, assessed by the thyroid-stimulating hormone (TSH) concentration at neonatal screening, on cognitive development of preschool children. A retrospective cohort study including 311 Belgian preschool children of 4-6 years old was c...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu7115450
更新日期:2015-11-02 00:00:00
abstract::Dietary protein restriction has beneficial impacts on metabolic health. B0AT1 (SLC6A19) is the major transporter of neutral amino acids at the intestinal epithelia and absorbs the bulk of the diet-derived neutral amino acids from the intestinal lumen. It also reabsorbs neutral amino acids in the renal proximal tubules...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11092024
更新日期:2019-08-29 00:00:00
abstract::Intermittent energy restriction combined with a Mediterranean diet (IER+MED) has shown promise to reduce body fat and insulin resistance. In the Multiethnic Cohort Adiposity Phenotype Study, Japanese Americans had the highest visceral adipose tissue (VAT) when adjusting for total adiposity. We conducted this pilot stu...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu11061386
更新日期:2019-06-20 00:00:00
abstract::The mango leaf extract rich in mangiferin Zynamite® improves exercise performance when combined with luteolin or quercetin ingested at least 48 h prior to exercise. To determine whether a single dose of Zynamite® administered 1 h before exercise increases repeated-sprint performance, 20 men and 20 women who were physi...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11112592
更新日期:2019-10-28 00:00:00
abstract::To clarify the anti-obesity effect of Allomyrina dichotoma larvae (ADL), we previously reported that ADL block adipocyte differentiation on 3T3-L1 cell lines through downregulation of transcription factors, such as peroxisome proliferator-activated receptor-γ (PPARG) and CCAAT/enhancer binding protein-α (CEBPA). In th...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu7031978
更新日期:2015-03-17 00:00:00
abstract::Dietary polyphenols are multi-target compounds that have been considered promising candidates in strategies for the mitigation of neurological diseases, acting particularly through reduction of microglia-driven neuroinflammation. In this study, an anthocyanin-rich extract obtained from Portuguese blueberries was subje...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12123670
更新日期:2020-11-28 00:00:00
abstract::Metabolically healthy (MH) and metabolically unhealthy (MUH) phenotypes can be present in any subject independently of their body mass index (BMI). However, factors related to the presence of these phenotypes are poorly understood. Therefore, the aim of this cross-sectional study is to describe the prevalence and char...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10040447
更新日期:2018-04-04 00:00:00
abstract::Polygonatum sibiricum (PS) rhizome, which contains glyceryl-1-monolinoleate as its primary active component, has been shown to improve insomnia in animal models. Based on these findings, we aimed to investigate the safety and efficacy of PS rhizome extract in improving sleep quality in individuals with mild insomnia. ...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu11081719
更新日期:2019-07-25 00:00:00
abstract::(1) Introduction: Current evidence on managing infants under six months with growth failure or other nutrition-related risk is sparse and low quality. This review aims to inform research priorities to fill this evidence gap, focusing on breastfeeding practices. (2) Methods: We searched PubMed, CINAHL Plus, and Cochran...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12072044
更新日期:2020-07-09 00:00:00
abstract::NutritionDay (nDay) is a project established by the Medical University of Vienna and the European Society for Clinical Nutrition and Metabolism (ESPEN) to audit the nutritional status of hospitalized patients and nursing home residents. This study aimed to evaluate nDay data describing the prevalence of hospital malnu...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu13010263
更新日期:2021-01-18 00:00:00
abstract::Anemia and micronutrient (MN) deficiencies in pregnant women are associated with adverse pregnancy outcomes. In Niger, 58.6% of pregnant women are anemic; however, MN statuses are unknown. The study objectives were to estimate the prevalence of MN deficiencies among pregnant women in Zinder, Niger and explore associat...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9050430
更新日期:2017-04-26 00:00:00
abstract::Craniofacial development requires extremely fine-tuned developmental coordination of multiple specialized tissues. It has been evidenced that a folate deficiency (vitamin B9), or its synthetic form, folic acid (FA), in maternal diet could trigger multiple craniofacial malformations as oral clefts, tongue, or mandible ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu13010251
更新日期:2021-01-16 00:00:00
abstract::Vitamin A insufficiency has profound adverse effects on embryonic development. Major advances in understanding the role of vitamin A in vertebrate heart formation have been made since the discovery that the vitamin A active form, all-trans-retinoic acid, regulates many genes, including developmental genes. Among the e...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu2050532
更新日期:2010-05-01 00:00:00
abstract::Normal maternal thyroid function during pregnancy is essential for fetal development and depends upon an adequate supply of iodine. Little is known about how iodine status is associated with preterm birth and small for gestational age (SGA) in mildly iodine insufficient populations. Our objective was to evaluate assoc...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11112573
更新日期:2019-10-25 00:00:00
abstract::The biologically active form of vitamin D3, 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3), modulates innate and adaptive immunity via genes regulated by the transcription factor vitamin D receptor (VDR). In order to identify the key vitamin D target genes involved in these processes, transcriptome-wide datasets were compare...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12041140
更新日期:2020-04-19 00:00:00