Abstract:
:A dietary prebiotic is defined as 'a substrate that is selectively utilized by host microorganisms conferring a health benefit'. Although this definition evolved concomitantly with the knowledge and technological developments that accrued in the last twenty years, what qualifies as prebiotic continues to be a matter of debate. In this statement, we report the outcome of a workshop where academic experts working in the field of prebiotic research met with scientists from industry. The workshop covered three main topics: (i) evolution of the prebiotic concept/definition; (ii) the gut modeling in vitro technology PolyFermS to study prebiotic effects; and (iii) the potential novel microbiome-modulating effects associated with vitamins. The future of prebiotic research is very promising. Indeed, the technological developments observed in recent years provide scientists with powerful tools to investigate the complex ecosystem of gut microbiota. Combining multiple in vitro approaches with in vivo studies is key to understanding the mechanisms of action of prebiotics consumption and their potential beneficial effects on the host.
journal_name
Nutrientsjournal_title
Nutrientsauthors
La Fata G,Rastall RA,Lacroix C,Harmsen HJM,Mohajeri MH,Weber P,Steinert REdoi
10.3390/nu9121376subject
Has Abstractpub_date
2017-12-20 00:00:00issue
12issn
2072-6643pii
nu9121376journal_volume
9pub_type
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