Abstract：
:Endocrine disruptors (EDCs) have been associated with the increased incidence of metabolic disorders. In this work, we conducted a systematic review of the literature in order to identify the current knowledge of the interactions between EDCs in food, the gut microbiota, and metabolic disorders in order to shed light on this complex triad. Exposure to EDCs induces a series of changes including microbial dysbiosis and the induction of xenobiotic pathways and associated genes, enzymes, and metabolites involved in EDC metabolism. The products and by-products released following the microbial metabolism of EDCs can be taken up by the host; therefore, changes in the composition of the microbiota and in the production of microbial metabolites could have a major impact on host metabolism and the development of diseases. The remediation of EDC-induced changes in the gut microbiota might represent an alternative course for the treatment and prevention of metabolic diseases.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Gálvez-Ontiveros Y,Páez S,Monteagudo C,Rivas Adoi
10.3390/nu12041158subject
Has Abstractpub_date
2020-04-21 00:00:00issue
4issn
2072-6643pii
nu12041158journal_volume
12pub_type
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