Aerosol immunization by alginate coated mycobacterium (BCG/MIP) particles provide enhanced immune response and protective efficacy than aerosol of plain mycobacterium against M.tb. H37Rv infection in mice.

abstract：BACKGROUND:On 18 August 2015, Kyegegwa District reported eight deaths during a measles outbreak to the Uganda Ministry of Health (MoH). We investigated this death cluster to verify the cause, identify risk factors, and inform public health interventions. METHODS:We defined a probable measles case as onset of fever and...

journal_title：BMC infectious diseases

authors： Mafigiri R,Nsubuga F,Ario AR

更新日期：2017-07-03 00:00:00

abstract：BACKGROUND:Patients with HIV infection are at risk of co-infection with HBV, as the routes of transmission are shared and thus immunization with HBV vaccine could be protective in them. The aim of the present study was to assess the efficacy of recombinant vaccine in treatment-naive HIV positive patients and healthy co...

journal_title：BMC infectious diseases

authors： Pasricha N,Datta U,Chawla Y,Singh S,Arora SK,Sud A,Minz RW,Saikia B,Singh H,James I,Sehgal S

更新日期：2006-03-30 00:00:00

abstract：BACKGROUND:Rapid diagnostic tests (RDTs) are alternative methods for microscopy in the diagnosis of malaria in resource limited settings. Among commercially available RDTs, CareStart™ Malaria test was found to show reliable results. This study evaluated the performance of CareStart™ Malaria Combo test kit in Northweste...

journal_title：BMC infectious diseases

authors： Feleke DG,Tarko S,Hadush H

更新日期：2017-06-06 00:00:00

abstract：BACKGROUND:The new HIV treatment guidelines in China recommend antiretroviral therapy (ART) for all people living with HIV, but significant gaps in implementation still exist. Pre-exposure prophylaxis (PrEP) can effectively reduce the risk of HIV transmission among men who have sex with men (MSM). This study assessed t...

journal_title：BMC infectious diseases

authors： Li J,Peng L,Gilmour S,Gu J,Ruan Y,Zou H,Hao C,Hao Y,Lau JT

更新日期：2018-11-28 00:00:00

abstract：BACKGROUND:Implant-related infections, including those of peri-prosthetic joint (PJIs), osteosynthesis and other biomaterials, are biofilm-related. Pathogen identification is considered the diagnostic benchmark; however, the presence of bacterial biofilms makes pathogen detection with traditional microbiological techni...

journal_title：BMC infectious diseases

authors： Romanò CL,Trentinaglia MT,De Vecchi E,Logoluso N,George DA,Morelli I,Drago L

更新日期：2018-04-02 00:00:00

abstract：BACKGROUND:Pneumocystis jirovecii pneumonia (PJP) can be challenging to diagnose, often requiring bronchoscopy. Since most patients suspected of PJP undergo imaging, we hypothesized that the findings of these studies could help estimate the probability of disease prior to invasive testing. METHODS:We created a cohort ...

journal_title：BMC infectious diseases

authors： Hsu JM,Hass A,Gingras MA,Chong J,Costiniuk C,Ezer N,Fraser RS,McDonald EG,Lee TC

更新日期：2020-07-10 00:00:00

abstract：BACKGROUND:To investigate a possible role of Cefditoren, a recently marketed in Greece third-generation oral cephalosporin in urinary infections of outpatients. METHODS:During a multicenter survey of Enterobacteriaceae causing UTIs in outpatients during 2005-2007, Cefditoren MICs were determined by agar dilution metho...

journal_title：BMC infectious diseases

authors： Hatzaki D,Poulakou G,Katsarolis I,Lambri N,Souli M,Deliolanis I,Nikolopoulos GK,Lebessi E,Giamarellou H

更新日期：2012-09-25 00:00:00

abstract：BACKGROUND:Cytomegalovirus (CMV) pneumonitis has been shown to be associated with lymphocytic alveolitis after lung transplantation. In the present study, we investigated a series of bronchoalveolar (BAL) and blood samples, collected in the absence of rejection or acute infectious episodes. in order -1: to evaluate int...

journal_title：BMC infectious diseases

authors： Stéphan F,Bernaudin JF,Cesari D,Fajac A,Grenet D D,Caubarrere I,Stern M

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Australia is developing a chlamydia screening program. This study aimed to determine the attitudes of young women to the introduction of chlamydia screening in Australian General Practice. METHODS:In-depth face-to-face interviews with 24 young women from across Victoria, Australia, attending a randomly sele...

journal_title：BMC infectious diseases

authors： Pavlin NL,Parker R,Fairley CK,Gunn JM,Hocking J

更新日期：2008-05-09 00:00:00

abstract：BACKGROUND:Brucellosis is a zoonotic disease caused by brucella. It has been an increasing trend in recent years (Wang H, Xu WM, Zhu KJ, Zhu SJ, Zhang HF, Wang J, Yang Y, Shao FY, Jiang NM, Tao ZY, Jin HY, Tang Y, Huo LL, Dong F, Li ZJ, Ding H, Liu ZG, Emerg Microbes Infect 9:889-99, 2020). Brucellosis is capable to in...

journal_title：BMC infectious diseases

authors： Geng L,Feng Y,Li D,Nan N,Ma K,Tang X,Li X

更新日期：2020-09-07 00:00:00

abstract：BACKGROUND:Prion diseases are caused by the accumulation of an aberrantly folded isoform of the prion protein, designated PrPSc. In a cell-based assay, quinacrine inhibits the conversion of normal host prion protein (PrPC) to PrPSc at a half-maximal concentration of 300 nM. While these data suggest that quinacrine may ...

journal_title：BMC infectious diseases

authors： Yung L,Huang Y,Lessard P,Legname G,Lin ET,Baldwin M,Prusiner SB,Ryou C,Guglielmo BJ

更新日期：2004-11-29 00:00:00

abstract：:Following publication. ...

journal_title：BMC infectious diseases

authors： Almeida A,Codeço C,Luz PM

更新日期：2019-03-04 00:00:00

abstract：BACKGROUND:Low serum selenium has been associated with lower CD4 counts and greater mortality among HIV-1-seropositive individuals, but most studies have not controlled for serum albumin and the presence of an acute phase response. METHODS:A cross-sectional study was conducted to evaluate relationships between serum s...

journal_title：BMC infectious diseases

authors： Drain PK,Baeten JM,Overbaugh J,Wener MH,Bankson DD,Lavreys L,Mandaliya K,Ndinya-Achola JO,McClelland RS

更新日期：2006-05-19 00:00:00

abstract：BACKGROUND:Granulysin (GNLY) is produced by human lymphocyte subpopulations and exhibits antimicrobial activity against Mycobacterium tuberculosis. We examined the association between GNLY levels in blood and latent tuberculosis (TB) infection. METHODS:Latency of TB infection among Vietnamese healthcare workers was es...

journal_title：BMC infectious diseases

authors： Thuong PH,Tam DB,Sakurada S,Hang NT,Hijikata M,Hong LT,Ngoc PT,Anh PT,Cuong VC,Matsushita I,Lien LT,Keicho N

更新日期：2016-10-18 00:00:00

abstract：BACKGROUND:Tuberculosis (TB) continues to be a public health challenge in Saudi Arabia, particularly for the elderly. This study was conducted to estimate mortality per 1000 person-year among TB and resistant TB cases and to identifying factors associated with mortality. METHODS:This is a retrospective cohort study of...

journal_title：BMC infectious diseases

authors： Aljadani R,Ahmed AE,Al-Jahdali H

更新日期：2019-05-16 00:00:00

abstract：BACKGROUND:Infection with cagA-positive, cagA EPIYA motif ABD type, and vacA s1, m1, and i1 genotype strains of Helicobacter pylori is associated with an exacerbated inflammatory response and increased risk of gastroduodenal diseases. However, it is unclear whether the prevalence and virulence factor genotypes found in...

journal_title：BMC infectious diseases

authors： Sahara S,Sugimoto M,Vilaichone RK,Mahachai V,Miyajima H,Furuta T,Yamaoka Y

更新日期：2012-09-21 00:00:00

abstract：BACKGROUND:NOD2, an intracellular pathogen recognition sensor, modulates innate defences to muropeptides derived from various bacterial species, including Mycobacterium tuberculosis (MTB). Experimentally, NOD2 attenuates two key putative mycobactericidal mechanisms. TNF-alpha synthesis is markedly reduced in MTB-antige...

journal_title：BMC infectious diseases

authors： Lala S,Dheda K,Chang JS,Huggett JF,Kim LU,Johnson MA,Rook GA,Keshav S,Zumla A

更新日期：2007-08-16 00:00:00

abstract：BACKGROUND:Oxidative stress plays a vital role in the pathogenesis of both Sickle Cell Disease (SCD) and Plasmodium falciparum malaria. However, there are limited studies on the effect of P. falciparum malaria infection on oxidative stress in SCD patients. METHODS:A cross-sectional study was undertaken to compare leve...

journal_title：BMC infectious diseases

authors： Atiku SM,Louise N,Kasozi DM

更新日期：2019-07-09 00:00:00

abstract：BACKGROUND:Cytopenias are the most common HIV-associated hematological abnormality. Cytopenias have been associated with several factors including sex, race/ethnicity, geographical location and comorbidities such as tuberculosis, hepatitis B infection, fever and oral candidiasis. Cytopenias become more prevalent as HIV...

journal_title：BMC infectious diseases

authors： Kyeyune R,Saathoff E,Ezeamama AE,Löscher T,Fawzi W,Guwatudde D

更新日期：2014-09-10 00:00:00

abstract：BACKGROUND:Diagnostic tests are generally used in situations with similar pre-test probability of disease to where they were developed. When these tests are applied in situations with very different pre-test probabilities of disease, it is informative to model the likely implications of known characteristics of test pe...

journal_title：BMC infectious diseases

authors： van Kampen SC,Anthony RM,Klatser PR

更新日期：2010-04-12 00:00:00

abstract：BACKGROUND:Egypt ranks fifth for the burden of viral hepatitis worldwide. As part of Egypt's renewed national strategy for the elimination of viral hepatitis, surveillance for acute viral hepatitis (AVH) was re-established during 2014-2017 to describe the current epidemiology and associated risk factors, and changes fr...

journal_title：BMC infectious diseases

authors： Talaat M,Afifi S,Reaves EJ,Abu Elsood H,El-Gohary A,Refaey S,Hammad R,Abdel Fadeel M,Kandeel A

更新日期：2019-02-14 00:00:00

abstract：BACKGROUND:Although a dramatic decrease in AIDS progression has been observed after Highly Active Anti Retroviral Therapy (HAART) in both low- and high-resource settings, few data support that fact in low-resource settings.This study describes the incidence of AIDS-defining illnesses (ADI) after HAART initiation and an...

journal_title：BMC infectious diseases

authors： De Beaudrap P,Etard JF,Diouf A,Ndiaye I,Ndèye GF,Sow PS,Ndèye KC,Ecochard R,Delaporte E,ANRS 1215 Study Group.

更新日期：2010-06-19 00:00:00

abstract：BACKGROUND:COVID-19 is novel infectious disease with an evolving understanding of its epidemiology and clinical manifestations. Severe cases developed life-threatening complications, such as respiratory failure, shock, and multiple organs dysfunction. Immunocompromised patients often present atypical presentations of v...

journal_title：BMC infectious diseases

authors： Zhang JC,Yu XH,Ding XH,Ma HY,Cai XQ,Kang SC,Xiang DW

更新日期：2020-10-19 00:00:00

abstract：BACKGROUND:Large scale administration of the anthelminthic drug praziquantel (PZQ) to at-risk populations is the cornerstone of schistosomiasis control, although persisting high prevalence of infections in some areas and growing concerns of PZQ resistance have revealed the limitations of this strategy. Most studies ass...

journal_title：BMC infectious diseases

authors： Hoekstra PT,Casacuberta Partal M,Amoah AS,van Lieshout L,Corstjens PLAM,Tsonaka S,Assaré RK,Silué KD,Meité A,N'Goran EK,N'Gbesso YK,Roestenberg M,Knopp S,Utzinger J,Coulibaly JT,van Dam GJ

更新日期：2018-12-14 00:00:00

abstract：BACKGROUND:Cryptococcus gattii is known to be an etiologic agent of human cryptococcosis, particularly in immunocompetent persons. C. gattii infection usually involves the central nervous system, the respiratory tract, or may be disseminated. Here we report an atypical manifestation of C. gattii infection in a patient ...

journal_title：BMC infectious diseases

authors： Dhitinanmuang W,Chongtrakool P,Jitmuang A

更新日期：2018-06-04 00:00:00

abstract：BACKGROUND:Kynurenine/Tryptophan ratio (KTR) is increased in HIV infection, and linked to immune activation. We hypothesized that early cART initiation results in lower KTR compared to late initiation. Furthermore, we hypothesized that KTR prior to cART is a predictor of the magnitude of subsequent reduction in immune ...

journal_title：BMC infectious diseases

authors： Gelpi M,Hartling HJ,Ueland PM,Ullum H,Trøseid M,Nielsen SD

更新日期：2017-05-16 00:00:00

abstract：BACKGROUND:Over the past several years, new diagnostic techniques have been developed to allow for the rapid detection of multidrug resistant tuberculosis. The GenoType MTBDRplus test is a deoxyribonucleic acid (DNA) strip assay which uses polymerase chain reaction (PCR) and hybridization to detect genetic mutations in...

journal_title：BMC infectious diseases

authors： Anek-Vorapong R,Sinthuwattanawibool C,Podewils LJ,McCarthy K,Ngamlert K,Promsarin B,Varma JK

更新日期：2010-05-20 00:00:00

abstract：BACKGROUND:Lemierre's syndrome presents a classic clinical picture, the pathophysiology of which remains obscure. Attempts have been made to trace genetic predispositions that modify the host detection of pathogen or the resultant systemic reaction. CASE PRESENTATION:A 17-year old female, with no previous medical hist...

journal_title：BMC infectious diseases

authors： Constantin JM,Mira JP,Guerin R,Cayot-Constantin S,Lesens O,Gourdon F,Romaszko JP,Linval P,Laurichesse H,Bazin JE

更新日期：2006-07-17 00:00:00

abstract：BACKGROUND:The differential expression of virulence genes is often used by microbial pathogens in adapting to the environment of their host. The differential expression of such sets of genes can be regulated by RNA polymerase sigma factors. Some sigma factors are differentially expressed, which can provide a means to i...

journal_title：BMC infectious diseases

authors： McLendon MM,Shinnick TM

更新日期：2003-07-11 00:00:00

abstract：BACKGROUND:A vaccine matched to a newly emerged pandemic influenza virus would require a production time of at least 6 months with current proven techniques, and so could only be used reactively after the peak of the pandemic. A pre-pandemic vaccine, although probably having lower efficacy, could be produced and used p...

journal_title：BMC infectious diseases

authors： Halder N,Kelso JK,Milne GJ

更新日期：2014-05-16 00:00:00