Abstract：
BACKGROUND:COVID-19 is novel infectious disease with an evolving understanding of its epidemiology and clinical manifestations. Severe cases developed life-threatening complications, such as respiratory failure, shock, and multiple organs dysfunction. Immunocompromised patients often present atypical presentations of viral infected diseases. CASE PRESENTATION:We report newly diagnosed HIV infections in two patients with COVID-19 in China. In our two cases, both patients with elevated IL-6 received Tocilizumab treatment, but did not present obvious therapeutic effect. CONCLUSIONS:These cases highlight possible co-detection of known immunocompromised diseases such as HIV. The two cases we reported stressed the risk of misdiagnosis, especially during the pandemic of an infectious disease and the importance of extended testing even if in immune-compromised condition the immune state may be ignored.
journal_name
BMC Infect Disjournal_title
BMC infectious diseasesauthors
Zhang JC,Yu XH,Ding XH,Ma HY,Cai XQ,Kang SC,Xiang DWdoi
10.1186/s12879-020-05480-ysubject
Has Abstractpub_date
2020-10-19 00:00:00pages
771issue
1issn
1471-2334pii
10.1186/s12879-020-05480-yjournal_volume
20pub_type
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