Abstract：
:Although remote ischemic preconditioning (RIPC) has been shown to have renoprotective effects, few studies have assessed the effects of RIPC on renal function in living kidney donors. This study investigated whether RIPC performed in living kidney donors could improve residual renal function in donors and outcomes in recipients following kidney transplantation. The donors were randomized into a control group (n = 85) and a RIPC group (n = 85). The recipients were included according to the matched donors. Serum creatinine (sCr) concentrations and estimated glomerular filtration rate (eGFR) were compared between control and RIPC groups in donors and recipients. Delayed graft function, acute rejection, and graft failure within one year after transplantation were evaluated in recipients. sCr was significantly increased in the control group (mean, 1.13; 95% confidence interval (CI), 1.07-1.18) than the RIPC group (1.01; 95% CI, 0.95-1.07) (p = 0.003) at discharge. Donors with serum creatinine >1.4 mg/dL at discharge had higher prevalence of chronic kidney disease (n = 6, 26.1%) than donors with a normal serum creatinine level (n = 8, 5.4%) (p = 0.003) after one year. sCr concentrations and eGFR were similar in the RIPC and control groups of recipients over the one-year follow-up period. Among recipients, no outcome variables differed significantly in the RIPC and control groups. RIPC was effective in improving early renal function in kidney donors but did not improve renal function in recipients.
journal_name
J Clin Medjournal_title
Journal of clinical medicineauthors
Bang JY,Kim SG,Oh J,Kim SO,Go YJ,Hwang GS,Song JGdoi
10.3390/jcm8050713subject
Has Abstractpub_date
2019-05-20 00:00:00issue
5issn
2077-0383pii
jcm8050713journal_volume
8pub_type
杂志文章abstract：:Pain in Sickle Cell Disease (SCD) is a major comorbidity and unique with acute pain due to recurrent and episodic vaso-occlusive crises as well as chronic pain, which can span an individual's entire life. Opioids are the mainstay treatment for pain in SCD. Due to recent health crises raised by adverse effects includin...
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更新日期：2020-09-27 00:00:00
abstract：:This study assessed the efficacy of intraoperative high-dose intravenous iron therapy in facilitating recovery from postoperative anemia and reducing the transfusion rate in patients with total knee and total hip arthroplasty. This prospective randomized controlled study involved 58 subjects. Group F received 1000 mg ...
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更新日期：2019-10-13 00:00:00
abstract：:In the past two decades, multiple studies have been undertaken to elucidate the genetic cause of the predisposition to mismatch repair (MMR)-proficient nonpolyposis colorectal cancer (CRC). Here, we present the proposed candidate genes according to their involvement in specific pathways considered relevant in heredita...
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更新日期：2020-06-23 00:00:00
abstract：:Preterm birth (PTB, <37 weeks) is the leading cause of death in children <5 years of age. Early risk prediction for PTB would enable early monitoring and intervention. However, such prediction models have been rarely reported, especially in low- and middle-income areas. We used data on a number of easily accessible pr...
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journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
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更新日期：2020-02-21 00:00:00
abstract：PURPOSE:To investigate the value of visual acuity and patient-perceived visual function test when subretinal drusenoid deposits (SDD) are incorporated into the classification of age-related macular degeneration (AMD). A total of 50 participants were recruited into the study in these groups: healthy ageing (n = 11), int...
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更新日期：2020-09-01 00:00:00
abstract：:The aim of the study was to investigate ultrasound tissue characterization of carotid plaques in subjects with and without diabetes type 1 (T1D). B-mode carotid ultrasound was performed to assess the presence and type of plaque in a group of 340 subjects with and 304 without T1D, all of them without cardiovascular dis...
journal_title：Journal of clinical medicine
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更新日期：2019-03-28 00:00:00
abstract：:The non-consensual sharing of an intimate image is a serious breach of a person's right to privacy and can lead to severe psychosocial consequences. However, little research has been conducted on the reasons for consuming intimate pictures that have been shared non-consensually. This study aims to investigate how the ...
journal_title：Journal of clinical medicine
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更新日期：2019-05-17 00:00:00
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更新日期：2019-04-13 00:00:00
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更新日期：2020-03-24 00:00:00
abstract：BACKGROUND:The clinical practice shows that many low-dose ACTH-stimulation tests have a false positive result. The aim of the study was to determine the diagnostic accuracy of a low-dose ACTH-stimulation test in the diagnosis of adrenal insufficiency and to define its optimal cut-off. METHODS:We analyzed data from 103...
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更新日期：2019-06-05 00:00:00
abstract：BACKGROUND:Due to its unknown etiology, the objective diagnosis and therapeutics of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) are still challenging. Generally, the patient-reported outcome (PRO) is the major strategy driving treatment response because the patient is the most important judge of whether...
journal_title：Journal of clinical medicine
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更新日期：2020-10-28 00:00:00
abstract：:The aim of this systematic review and meta-analysis was to evaluate the clinical performance of tooth-borne partial and full-coverage fixed dental prosthesis fabricated using hybrid polymer and ceramic CAD/CAM materials regarding their biologic, technical and esthetical outcomes. PICOS search strategy was applied usin...
journal_title：Journal of clinical medicine
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更新日期：2020-07-04 00:00:00
abstract：:Clinically, in young immunocompetent adults, Epstein-Barr virus (EBV) usually manifests as infectious mononucleosis (IM). Typical clinical findings of EBV IM include fever, profound fatigue, pharyngitis, bilateral posterior cervical adenopathy, and splenomegaly. Respiratory involvement with EBV IM may occur, but is di...
journal_title：Journal of clinical medicine
pub_type：
doi：10.3390/jcm6090083
更新日期：2017-09-04 00:00:00
abstract：:Fertility preservation in trans women is a crucial but thus far neglected component in the gender confirming treatment in Germany. It is difficult for trans women to access reproductive health care because centers offering treatment, psychological guidance, gender confirming surgery, as well as reproductive health ser...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm8050730
更新日期：2019-05-22 00:00:00
abstract：:The diagnosis of small-bowel tumors is challenging due to their low incidence, nonspecific presentation, and limitations of traditional endoscopic techniques. In our study, we examined the utility of the mucosal protrusion angle in differentiating between true submucosal masses and bulges of the small bowel on video c...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8040418
更新日期：2019-03-27 00:00:00
abstract：BACKGROUND:The Glasgow-Blatchford Score (GBS) is one of the most widely used scoring systems for predicting clinical outcomes for gastrointestinal bleeding (GIB). However, the clinical significance of the GBS in predicting GIB in patients with heart failure (HF) remains unclear. METHODS AND RESULTS:We conducted a pros...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9124083
更新日期：2020-12-17 00:00:00
abstract：:Multiple myeloma (MM) is a hematological malignancy with a poor prognosis, characterized by clonal proliferation of plasma cells in the bone marrow (BM). Relapse due to undetected minimal residual disease (MRD) is the leading cause of death among patients with MM. This review summarizes the methods and prognostic valu...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm6100091
更新日期：2017-09-25 00:00:00
abstract：:In the past, numerous non-operative treatments for adolescent idiopathic scoliosis (AIS), including exercise, physical therapy, electrical stimulation, and brace treatment, have been tried to delay or prevent the curve progression. Of these, brace treatment is the only option that is widely accepted and has demonstrat...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm7060136
更新日期：2018-06-04 00:00:00
abstract：:Joint bleeding represents the most commonly reported type of hemorrhage in patients affected by hemophilia. Although the widespread use of prophylaxis has been able to significantly reduce the onset of arthropathy, it has been shown that a non-negligible percentage of patients develop degenerative changes in their joi...
journal_title：Journal of clinical medicine
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doi：10.3390/jcm6080077
更新日期：2017-07-31 00:00:00
abstract：BACKGROUND:Our study aims to perform a meta-analysis of benefits and risks associated with the use of non-vitamin K oral anticoagulants (NOAC) versus vitamin K antagonists (VKA) in patients with a percutaneous coronary intervention (PCI) with a particular focus on the combination type: dual vs. dual antithrombotic ther...
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pub_type： 杂志文章
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更新日期：2020-04-14 00:00:00
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journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm8081197
更新日期：2019-08-11 00:00:00
abstract：:Postoperative ileus is one of the most important and common complications after abdominal surgery. This single-blind randomized clinical trial study was conducted with the aim of evaluating the effect of oral pyridostigmine (60 mg) on the duration and frequency of response to the treatment of ileus after abdominal sur...
journal_title：Journal of clinical medicine
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更新日期：2018-05-06 00:00:00
abstract：:Duchenne muscular dystrophy (DMD), the most severe form of dystrophinopathy, is quite homogeneous with regards to its causative biochemical defect, i.e., complete dystrophin deficiency, but not so much with regards to its phenotype. For instance, muscle weakness progresses to the loss of independent ambulation at a va...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
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更新日期：2019-05-10 00:00:00
abstract：OBJECTIVE:To investigate the risk and risk factors for suicide attempt by patients with regular migraines (RM) and status migrainosus (SM) in Taiwan. METHODS:We analyzed a subset of the National Health Insurance Research Database of Taiwan and enrolled patients (≥20 years old) who had ever received a diagnosis of RM o...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm7090269
更新日期：2018-09-11 00:00:00
abstract：:The main risk factor for primary open-angle glaucoma (POAG) is increased intraocular pressure (IOP). It is of interest that about half of the patients have an IOP within the normal range (normal-tension glaucoma, NTG). Additionally, there is a group of patients with a high IOP but no glaucomatous neurodegeneration (oc...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
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更新日期：2020-09-15 00:00:00
abstract：:Acute retinal necrosis (ARN) is a rare viral endophthalmitis, and human herpesvirus is the principal pathogen. Early diagnosis and treatment are critical to avoid visual impairment by ARN, and pars plana vitrectomy (PPV) is required in advanced cases. In this study, we evaluated the transition of viral load in ocular ...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9041204
更新日期：2020-04-22 00:00:00
abstract：:(1) Background: Omega-3 fatty acids (ω3FAs) are known to improve protein anabolism, increase the sensitivity to anabolic stimuli, decrease lipogenesis, and stimulate lipid oxidation. We aim to investigate whether ω3FAs are associated with the prevalence of sarcopenic obesity (SO). (2) Methods: Data were obtained from ...
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更新日期：2020-11-27 00:00:00
abstract：:Molecular mechanisms and pathological features of p-Cresyl sulfate (PCS)-induced uremic lung injury (ULI) in chronic kidney disease (CKD) remain unclear. We analyzed pleural effusions (PE) from CKD and non-CKD patients for uremic toxins, reactive oxygen species (ROS), and chemotactic cytokines. Correlations between PE...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm7090266
更新日期：2018-09-09 00:00:00
