Abstract：
:Fertility preservation in trans women is a crucial but thus far neglected component in the gender confirming treatment in Germany. It is difficult for trans women to access reproductive health care because centers offering treatment, psychological guidance, gender confirming surgery, as well as reproductive health services are scarce in Germany. Legal, social, or financial issues as well as individual patient comorbidities prevent trans women from receiving appropriate counselling. This review provides an overview on options of fertility preservation in trans women. We consider recent publications on testicular regression at the time of gender confirming surgery demonstrating presence of sperm or at least spermatogonia in the majority of tissues. This may open options for cryopreservation of sperm or testicular stem cells in trans women even at the final stage of transition. Hence, standardized urological procedures (i.e., sperm cryopreservation after masturbation or sperm extraction from the testicular tissue) and experimental approaches (cryopreservation of testicular tissue with undifferentiated spermatogonia) can be offered best at the initiation but also during the gender confirming process. However, counselling early in the gender confirming process increases the chances of fertility preservation because gender confirming hormone therapy has an impact on spermatogenesis.
journal_name
J Clin Medjournal_title
Journal of clinical medicineauthors
Schneider F,Scheffer B,Dabel J,Heckmann L,Schlatt S,Kliesch S,Neuhaus Ndoi
10.3390/jcm8050730subject
Has Abstractpub_date
2019-05-22 00:00:00issue
5issn
2077-0383pii
jcm8050730journal_volume
8pub_type
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journal_title：Journal of clinical medicine
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journal_title：Journal of clinical medicine
pub_type： 社论
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更新日期：2021-01-06 00:00:00
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更新日期：2020-06-29 00:00:00
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更新日期：2020-04-24 00:00:00
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更新日期：2020-02-22 00:00:00
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更新日期：2019-12-10 00:00:00
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doi：10.3390/jcm9082475
更新日期：2020-08-01 00:00:00
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journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9041243
更新日期：2020-04-24 00:00:00
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journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9123816
更新日期：2020-11-25 00:00:00
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journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm7120467
更新日期：2018-11-22 00:00:00
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journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8030295
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND:In mildly to moderately malnourished adolescent patients with anorexia nervosa (AN), accelerated refeeding protocols using higher initial calory supply coupled with phosphate supplements were not associated with a higher incidence of refeeding syndrome (RS). It is unclear whether this is also a feasible appr...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9051535
更新日期：2020-05-19 00:00:00
abstract：PURPOSE:Evasion of the immune system by cancer cells allows for the progression of tumors. Antitumor immunotherapy has shown remarkable effects in a diverse range of cancers. The aim of this study was to determine the clinicopathological significance of human epidermal growth factor receptor 2 (HER2), indoleamine 2,3-d...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9051265
更新日期：2020-04-27 00:00:00
abstract：INTRODUCTION:The inherent immunosuppression of uremia increases the susceptibility of hemodialysis patients to infection. There is still limited evidence on hemodialysis patients and COVID-19. The clinical and analytical spectrum and treatment responses and mortality are poorly characterized. MATERIAL AND METHODS:Clin...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9072264
更新日期：2020-07-16 00:00:00
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journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
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journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9041238
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pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2021-01-18 00:00:00
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pub_type： 杂志文章
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journal_title：Journal of clinical medicine
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journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
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更新日期：2021-01-21 00:00:00
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pub_type： 杂志文章
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更新日期：2020-06-04 00:00:00
abstract：:There is a large body of research showing that psychological treatment can be effectively delivered via the internet, and Digital Mental Health Services (DMHS) are now delivering those interventions in routine care. However, not all attempts to translate these research outcomes into routine care have been successful. ...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8081239
更新日期：2019-08-17 00:00:00
abstract：BACKGROUND AND AIMS:Data from clinical trials suggest that biological drugs may improve the outcomes in Crohn's disease (CD) by reducing the need for surgery or hospitalization. The aim of this study is to evaluate the time-trends of the use of biological drugs and other treatments for CD, and its relationship with out...
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更新日期：2020-09-08 00:00:00
