Unexplained Dyspnea in a Young Adult with Epstein-Barr Virus Infectious Mononucleosis: Pulmonary Involvement or Co-Infection with Mycoplasma pneumoniae Pneumonia?

abstract：:The aim of this systematic review with meta-analysis was to investigate the available literature on transoral approaches in the treatment of hypopharyngeal squamous cell carcinoma, with a special focus on transoral robotic surgery (TORS). A systematic review was conducted according to the PRISMA (preferred reporting i...

journal_title：Journal of clinical medicine

authors： De Virgilio A,Iocca O,Malvezzi L,Di Maio P,Pellini R,Ferreli F,Cugini G,Colombo G,Spriano G

更新日期：2019-02-18 00:00:00

abstract：:Immune checkpoint inhibitors (ICI) have revolutionised cancer therapy. However, they have been effective in only a small subset of patients and a principal mechanism underlying immune-refractoriness is a 'cold' tumour microenvironment, that is, lack of a T-cell-rich, spontaneously inflamed phenotype. As such, there is...

journal_title：Journal of clinical medicine

authors： Motedayen Aval L,Pease JE,Sharma R,Pinato DJ

更新日期：2020-10-16 00:00:00

abstract：:Many studies have shown a global efficacy of laparoscopic surgery for patients with endometriosis in reducing painful symptoms and improving quality of life (QoL) in the short and long-term. The aim of this study was to analyze the different trajectories of long-term evolution in QoL and symptoms following surgical tr...

journal_title：Journal of clinical medicine

authors： Comptour A,Lambert C,Chauvet P,Figuier C,Gremeau AS,Canis M,Pereira B,Bourdel N

更新日期：2020-07-31 00:00:00

abstract：:(1) Background: We evaluated macular ganglion cell layer-inner plexiform layer (GCL-IPL) thickness in patients with primary macula-off rhegmatogenous retinal detachment (RRD) treated with scleral buckling (SB) or pars plana vitrectomy (PPV) using spectral domain optical coherence tomography (SD-OCT). (2) Methods: In t...

journal_title：Journal of clinical medicine

authors： Gharbiya M,Albanese GM,Plateroti AM,Marcelli M,Marenco M,Lambiase A

更新日期：2020-05-10 00:00:00

abstract：:Our study aimed to clarify the neuroimaging correlates of suicide attempt by comparing differences in functional magnetic resonance imaging (fMRI) among depressed suicide attempters, depressed patients without suicide attempt history, and healthy controls through comprehensive and novel fMRI analyses and methods in th...

journal_title：Journal of clinical medicine

authors： Weng JC,Chou YS,Tsai YH,Lee CT,Hsieh MH,Chen VC

更新日期：2019-11-14 00:00:00

abstract：:In the SImplification of Medications Prescribed to Long-tErm care Residents (SIMPLER) cluster-randomized controlled trial, we evaluated the impact of structured medication regimen simplification on medication administration times, falls, hospitalization, and mortality at 8 residential aged care facilities (RACFs) at 1...

journal_title：Journal of clinical medicine

authors： Sluggett JK,Hopkins RE,Chen EY,Ilomäki J,Corlis M,Van Emden J,Hogan M,Caporale T,Ooi CE,Hilmer SN,Bell JS

更新日期：2020-04-08 00:00:00

abstract：BACKGROUND:Ocular involvement in Psoriatic Arthritis (PsA) patients is mainly associated with uveitis but there remains a paucity of data on dry eye and retinal abnormalities. We aimed to analyze dry eye and subclinical retinal abnormalities in a cohort of PsA patients sine-psoriasis (PsO). METHODS:PsA patients sine-P...

journal_title：Journal of clinical medicine

authors： Chimenti MS,Triggianese P,Salandri G,Conigliaro P,Canofari C,Caso F,Costa L,Nucci C,Aiello F,Cesareo M,Perricone R

更新日期：2020-03-06 00:00:00

abstract：BACKGROUND:For acute adnexal torsion of pregnant women, appropriate treatment based on an accurate diagnosis is especially important for fertility preservation and timely treatment. The 2017 American College of Obstetricians and Gynecologists (ACOG) Committee Opinion No. 723 announced its practice-changing guidelines t...

journal_title：Journal of clinical medicine

authors： Lee JH,Roh HJ,Ahn JW,Kim JS,Choi JY,Lee SJ,Lee SH

更新日期：2020-07-13 00:00:00

abstract：:Major depression disorder (MDD) is the most prevalent psychiatric comorbid condition in cocaine use disorder (CUD). The comorbid MDD might be primary-MDD (CUD-primary-MDD) or cocaine-induced MDD (CUD-induced-MDD), and their accurate diagnoses and treatment is a challenge for improving prognoses. This study aimed to as...

journal_title：Journal of clinical medicine

authors： Fonseca F,Mestre-Pintó JI,Gómez-Gómez À,Martinez-Sanvisens D,Rodríguez-Minguela R,Papaseit E,Pérez-Mañá C,Langohr K,Valverde O,Pozo ÓJ,Farré M,Torrens M,On Behalf Of Neurodep Group

更新日期：2020-12-19 00:00:00

abstract：:In excess of three quarters of patients with psoriatic arthritis (PsA) have preceding psoriasis (PsO), which offers a clinical biomarker for the recognition of early PsA. Numerous surveys have shown a remarkably high frequency of clinically occult musculoskeletal symptoms in psoriasis patients. Imaging studies, partic...

journal_title：Journal of clinical medicine

authors： Savage L,Tinazzi I,Zabotti A,Laws PM,Wittmann M,McGonagle D

更新日期：2020-10-12 00:00:00

abstract：:Pigmented villonodular synovitis (PVNS) of the ankle is a very rare, locally aggressive, proliferative disorder. Although surgical excision represents the standard curative treatment, the PVNS relapse rate is high. We present our study of five young athletes (range 20-36 years) with a histopathological diagnosis of PV...

journal_title：Journal of clinical medicine

authors： Iakovou I,Symeonidis P,Kotrotsios D,Giannoula E,Sachpekidis C

更新日期：2020-02-22 00:00:00

abstract：:Liver transplantation is increasingly dependent on the use of extended criteria donors (ECD) to increase the organ donor pool and address rising demand. This has necessitated the adoption of innovative technologies and strategies to protect these higher-risk grafts from the deleterious effects of traditional preservat...

journal_title：Journal of clinical medicine

authors： Dengu F,Abbas SH,Ebeling G,Nasralla D

更新日期：2020-04-07 00:00:00

abstract：:Approximately 5% of patients with IgA nephropathy (IgAN) exhibit mild mesangial lesions with acute onset nephrotic syndrome and diffuse foot process effacement representative of minimal change disease (MCD). It is not clear whether these unusual cases of IgAN with MCD (IgAN-MCD) are variant types of IgAN or coincident...

journal_title：Journal of clinical medicine

authors： Cho WH,Park SH,Choi SK,Jung SW,Jeong KH,Kim YG,Moon JY,Lim SJ,Sung JY,Jhee JH,Chin HJ,Choi BS,Lee SH

更新日期：2020-08-12 00:00:00

abstract：:Rhinosinusitis (RS) is a common disease in children, significantly affecting their quality of life. Chronic rhinosinusitis (CRS) is frequently linked to other respiratory diseases, including asthma. Children affected by CRS may be candidates for surgery in the case of failure of maximal medical therapy comprising thre...

journal_title：Journal of clinical medicine

authors： Torretta S,Guastella C,Ibba T,Gaffuri M,Pignataro L

更新日期：2019-05-15 00:00:00

abstract：:The 2018 update of the Global Strategy for Asthma Management and Prevention does not mention fatigue-related symptoms. Nevertheless, patients with asthma frequently report tiredness, lack of energy, and daytime sleepiness. Quantitative research regarding the prevalence of fatigue in asthmatic patients is lacking. This...

journal_title：Journal of clinical medicine

authors： Van Herck M,Spruit MA,Burtin C,Djamin R,Antons J,Goërtz YMJ,Ebadi Z,Janssen DJA,Vercoulen JH,Peters JB,Thong MSY,Otker J,Coors A,Sprangers MAG,Muris JWM,Wouters EFM,van 't Hul AJ

更新日期：2018-11-23 00:00:00

abstract：:The relationship between serum uric acid (SUA) and hypertension has been a subject of increasing interest since the 1870 discovery by Frederick Akbar Mahomed. Several epidemiological studies have shown a strong association between high SUA levels and the presence or the development of hypertension. Genetic analyses ha...

journal_title：Journal of clinical medicine

authors： Piani F,Cicero AFG,Borghi C

更新日期：2021-01-24 00:00:00

abstract：:The diagnosis of hereditary hemorrhagic telangiectasia (HHT) is based on the Curaçao criteria: epistaxis, telangiectases, arteriovenous malformations in internal organs, and family history. Genetically speaking, more than 90% of HHT patients show mutations in ENG or ACVRL1/ALK1 genes, both belonging to the TGF-β/BMP9 ...

journal_title：Journal of clinical medicine

authors： Albiñana V,Cuesta AM,Rojas-P I,Gallardo-Vara E,Recio-Poveda L,Bernabéu C,Botella LM

更新日期：2020-06-06 00:00:00

abstract：:Actinic cheilitis (AC) is one of the most frequent pathologies to affect the lips. Studies show that the most commonplace oral malignancy, squamous cell carcinoma (SCC), often emerges from AC lesions. Invasive diagnostic techniques performed on the lips carry a high risk of complications, but reflectance confocal micr...

journal_title：Journal of clinical medicine

authors： Lupu M,Caruntu A,Boda D,Caruntu C

更新日期：2020-06-25 00:00:00

abstract：:This phase II randomized controlled trial tested whether intracoronary autologous CD34+ cell therapy could further improve left ventricular (LV) systolic function in patients with diffuse coronary artery disease (CAD) with relatively preserved LV ejection fraction (defined as LVEF >40%) unsuitable for coronary interve...

journal_title：Journal of clinical medicine

authors： Sung PH,Li YC,Lee MS,Hsiao HY,Ma MC,Pei SN,Chiang HJ,Lee FY,Yip HK

更新日期：2020-04-07 00:00:00

abstract：:The purpose of this study was to report on the clinical usefulness of the Liver Disease Quality of Life Instrument (LDQOL) 1.0, which was prospectively measured in chronic hepatitis B patients. We regularly followed up with patients with chronic hepatitis B between 2008 and 2010 who were enrolled in the study, and the...

journal_title：Journal of clinical medicine

authors： Ha Y,Hwang S,Chon YE,Kim MN,Lee JH,Hwang SG

更新日期：2019-05-10 00:00:00

abstract：BACKGROUND:Nine percent of all cases of tuberculosis are bone and joint tuberculosis (BJTB). BJTB occurs in two main forms: spinal (STB) and extraspinal (ESTB). The aim of this study was to compare STB with ESTB in terms of diagnosis, treatment and outcomes. METHODS:We collected demographic, clinical, microbiological,...

journal_title：Journal of clinical medicine

authors： Guillouzouic A,Andrejak C,Peuchant O,Hery-Arnaud G,Hamdad F,Lanotte P,Gaborit B,Bernard L,Bémer P

更新日期：2020-08-05 00:00:00

abstract：:The burden of illness related to diabetes and its complications is exceedingly high and growing globally. Systematic approaches to managing chronic care are needed to address the complex nature of the disease, taking into account health system structures. This study presents data collected from interviews with physici...

journal_title：Journal of clinical medicine

authors： Bazzano AN,Wharton MK,Monnette A,Nauman E,Price-Haywood E,Glover C,Dominick P,Malone P,Hu G,Shi L

更新日期：2018-11-20 00:00:00

abstract：:Acute kidney injury (AKI) is a frequent complication of hospitalized patients with infective endocarditis (IE). Further, AKI in the setting of IE is associated with high morbidity and mortality. We aimed to examine the incidence, clinical parameters, and hospital costs associated with AKI in hospitalized patients with...

journal_title：Journal of clinical medicine

authors： Ortiz-Soriano V,Donaldson K,Du G,Li Y,Lambert J,Cleland D,Thornton A,Fanucchi LC,Huaman MA,Neyra JA

更新日期：2019-06-27 00:00:00

abstract：:We investigated the prognostic value of standard electroencephalography, a 30-min recording using 21 electrodes on the scalp, during the early post-cardiac arrest period, and evaluated the performance of electroencephalography findings combined with other clinical features for predicting favourable outcomes in comatos...

journal_title：Journal of clinical medicine

authors： Kim YJ,Kim MJ,Koo YS,Kim WY

更新日期：2020-04-13 00:00:00

abstract：:Attention deficit hyperactivity disorder (ADHD) is a frequent neurodevelopmental disorder that often persists into adulthood. Methylphenidate (MPH) is the first-line treatment for ADHD; however, despite its wide usage, little is known about its neurometabolic effects. Until now, no randomized and blinded clinical tria...

journal_title：Journal of clinical medicine

authors： Maier S,Tebartz van Elst L,Philipsen A,Lange T,Feige B,Glauche V,Nickel K,Matthies S,Alm B,Sobanski E,Domschke K,Perlov E,Endres D

更新日期：2020-08-11 00:00:00

abstract：:Thyroid hormones (THs) exert pleiotropic effects in different mammalian organs, including gonads. Genetic and non-genetic factors, such as ageing and environmental stressors (e.g., low-iodine intake, exposure to endocrine disruptors, etc.), can alter T4/T3 synthesis by the thyroid. In any case, peripheral T3, controll...

journal_title：Journal of clinical medicine

authors： Colella M,Cuomo D,Giacco A,Mallardo M,De Felice M,Ambrosino C

更新日期：2020-06-01 00:00:00

abstract：:The idea of right heart catheterization (RHC) grew in the milieu of modern thinking about the cardiovascular system, influenced by the experiments of William Harvey, which were inspired by the treatises of Greek philosophers like Aristotle and Gallen, who made significant contributions to the subject. RHC was first di...

journal_title：Journal of clinical medicine

authors： Kubiak GM,Ciarka A,Biniecka M,Ceranowicz P

更新日期：2019-08-28 00:00:00

abstract：:This study evaluated the efficacy of Lactobacillus acidophilus YT1 (MENOLACTO) for alleviating menopausal symptoms. This study was a multi-center, randomized, double-blinded, placebo-controlled clinical trial involving female subjects (ages: 40-60 years) with menopausal symptoms and a Kupperman index (KMI) score ≥ 20....

journal_title：Journal of clinical medicine

authors： Lim EY,Lee SY,Shin HS,Lee J,Nam YD,Lee DO,Lee JY,Yeon SH,Son RH,Park CL,Heo YH,Kim YT

更新日期：2020-07-09 00:00:00

abstract：:(1) Despite many years of research, melanoma still remains a big challenge for modern medicine. The purpose of this article is to review publicly available clinical trials to find trends regarding the number of trials, their location, and interventions including the most frequently studied drugs and their combinations...

journal_title：Journal of clinical medicine

authors： Wróbel S,Przybyło M,Stępień E

更新日期：2019-03-15 00:00:00

abstract：:The burden of cardiovascular disease and death in chronic kidney disease (CKD) outpaces that of the other diseases and is not adequately described by traditional risk factors alone. Diminished activity of paraoxonase (PON)-1 is associated with increased oxidant stress, a common feature underlying the pathogenesis of C...

journal_title：Journal of clinical medicine

authors： Mohammed CJ,Xie Y,Brewster PS,Ghosh S,Dube P,Sarsour T,Kleinhenz AL,Crawford EL,Malhotra D,James RW,Kalra PA,Haller ST,Kennedy DJ

更新日期：2019-07-15 00:00:00