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Defining Pre-Clinical Psoriatic Arthritis in an Integrated Dermato-Rheumatology Environment.

Abstract：

:In excess of three quarters of patients with psoriatic arthritis (PsA) have preceding psoriasis (PsO), which offers a clinical biomarker for the recognition of early PsA. Numerous surveys have shown a remarkably high frequency of clinically occult musculoskeletal symptoms in psoriasis patients. Imaging studies, particularly ultrasound, show a high prevalence of subclinical enthesitis and other inflammatory changes in psoriasis subjects. Since a serum biomarker, such as the case of anti-citrullinated protein antibodies (ACPA) in rheumatoid arthritis, neither exists nor seems biologically plausible at this point, this article explores how integration of rheumatological and dermatological assessment can be facilitated for the early recognition of potential PsA. Given that scalp disease is a PsA predictor, but may be managed in the community, then a particular need to access this group is needed. An integrated approach between rheumatology and dermatology can involve joint clinics, parallel clinics with discussion of relevant cases or virtual contact between specialties. Early therapy evaluation and integrated strategies have considerable implications for minimizing suffering and joint damage in PsA.

journal_name

J Clin Med

journal_title

Journal of clinical medicine

authors

Savage L,Tinazzi I,Zabotti A,Laws PM,Wittmann M,McGonagle D

doi

10.3390/jcm9103262

subject

Has Abstract

pub_date

2020-10-12 00:00:00

issue

10

issn

2077-0383

pii

jcm9103262

journal_volume

9

pub_type

杂志文章,评审

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