Abstract:
:Despite cardioprotective effects of a healthy diet in the general population, few studies have investigated this relationship in individuals with type 1 diabetes, who are at elevated risks of cardiovascular disease (CVD) due to hyperglycemia. The objective of this study was to examine the association of CVD biomarkers with overall diet quality, as measured by the Healthy Eating Index-2015 (HEI-2015), and its dietary components in youth with type 1 diabetes. Youth with type 1 diabetes (n = 136, 8⁻16.9 years) were enrolled in an 18-month behavioral nutrition intervention trial. Dietary intake from three-day diet records, CVD biomarkers (total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C); triglycerides (TG), C-reactive protein (CRP), 8-iso-prostaglandin-F2alpha (8-iso-PGF2α), systolic and diastolic blood pressure (SBP and DBP, respectively), and glycated hemoglobin (HbA1c) were assessed at baseline, 6, 12 and 18 months. Linear mixed-effects models estimated associations of dietary intake with CVD biomarkers, adjusting for HbA1c and other covariates. Separate models estimated associations of time-varying change in dietary intake with time-varying change in CVD biomarkers. HEI-2015 was not associated with CVD biomarkers, but whole grain intake was inversely associated with TC, HDL-C and DBP, and a greater increase in whole fruit intake was associated with lower DBP. Added sugar, saturated fat and polyunsaturated fat were positively related to serum TG, HDL-C, and DBP, respectively. Findings suggest that the intake of specific dietary components, including whole grains, whole fruits, added sugar and PUFA, may influence cardiometabolic health in youth with type 1 diabetes, independent of glycemic control.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Sanjeevi N,Lipsky LM,Nansel TRdoi
10.3390/nu10101552subject
Has Abstractpub_date
2018-10-19 00:00:00issue
10issn
2072-6643pii
nu10101552journal_volume
10pub_type
杂志文章相关文献
Nutrients文献大全abstract::Poor nutritional status is common among human immunodeficiency virus (HIV)-infected patients including vitamin D (vitD₃) deficiency. We conducted a double-blinded, randomized, and placebo-controlled trial in Addis Ababa, Ethiopia, to investigate if daily nutritional supplementation with vitD₃ (5000 IU) and phenylbutyr...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu11010133
更新日期:2019-01-10 00:00:00
abstract::Carotenoids are diet-dependent milk components that are important for the visual and cognitive development of an infant. This study determined β-carotene, lycopene and lutein + zeaxanthin in breastmilk and its associations with dietary intake from healthy Polish mothers in the first six months of lactation. Concentrat...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11010193
更新日期:2019-01-18 00:00:00
abstract::Glycemic control and weight reduction are primary goals for the management of overweight and obese type 2 diabetes mellitus (T2DM). Effective management cannot be achieved without an appropriate diet. Our study aimed to evaluate the short- and long-term effects of oat intake and develop a reasonable dietary plan for o...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu8090549
更新日期:2016-09-07 00:00:00
abstract::Women with polycystic ovary syndrome (PCOS) are at an increased risk of developing insulin resistance and abdominal obesity in the state of an improper diet balance. Leptin is a peptide considered to be a satiety hormone that plays an important role in the long-term energy balance, whereas ghrelin is a hormone that co...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12092753
更新日期:2020-09-10 00:00:00
abstract::The Mediterranean diet (MD) is recognized as one of the healthiest dietary patterns and has benefits such as improving glycaemic control among patients with type 2 diabetes (T2DM). Our aim is to assess the effectiveness of a multifactorial intervention to improve adherence to the MD, diet quality and biomedical parame...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu11010162
更新日期:2019-01-14 00:00:00
abstract::Dermatitis herpetiformis (DH) is a common extraintestinal manifestation of coeliac disease presenting with itchy papules and vesicles on the elbows, knees, and buttocks. Overt gastrointestinal symptoms are rare. Diagnosis of DH is easily confirmed by immunofluorescence biopsy showing pathognomonic granular immunoglobu...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu10050602
更新日期:2018-05-12 00:00:00
abstract::After enforcement of a new food labeling law in 2016, Chile exhibits a greater offer to reduced sugar products with addition of non-nutritive sweeteners (NNS). Many of these products are consumed by children, who are at greater risk of reaching the acceptable daily intake (ADI) of these food additives. The objective o...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12061594
更新日期:2020-05-29 00:00:00
abstract::The rating of perceived exertion (RPE) indicates the feeling of fatigue. However, hypoxia worsens the condition and can worsen RPE. We evaluated whether carbohydrate and glutamine supplementation alters RPE and physiological markers in running at 70% peak oxygen uptake until exhaustion in a simulated altitude of 4500 ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12123797
更新日期:2020-12-11 00:00:00
abstract::Obesity is a condition of rising prevalence worldwide, with important socioeconomic implications, being considered as a growing public health concern. Frequently, obesity brings other complications in addition to itself-like Type 2 Diabetes Mellitus (T2DM)-sharing origin, risk factors and pathophysiological mechanisms...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12092749
更新日期:2020-09-09 00:00:00
abstract::Breastfeeding is natural and the optimal basis of infant nutrition and development, with many benefits for maternal health. Human milk is a dynamic fluid fulfilling an infant's specific nutritional requirements and guiding the growth, developmental, and physiological processes of the infant. Human milk is considered u...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12071952
更新日期:2020-06-30 00:00:00
abstract::A cross-over study was conducted in 16 healthy adult volunteers to describe the urinary excretion of polyphenols from date seeds and investigate the antioxidant effect after consumption of different doses of date seeds powder (DSP), bread (DSB) and extract (DSE). After 12 h of fasting, one of the six treatments (0.25 ...
journal_title:Nutrients
pub_type: 临床试验,杂志文章
doi:10.3390/nu11102489
更新日期:2019-10-16 00:00:00
abstract::Various aspects of protein intake are thought to be crucial for the prevention of sarcopenia in older adults. Information about the day-to-day variation in these aspects is lacking. Our objective was to examine whether daily protein intake, protein distribution across meals, number of meals providing adequate protein,...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10091217
更新日期:2018-09-03 00:00:00
abstract::Omega-3 long-chain polyunsaturated fatty acids play a central role in neuronal growth and in the development of the human brain, since they are essential elements which depend on intake through diet to ensure an adequate amount. Fish and seafood are the main dietary sources of these fatty acids in Spain and in other c...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12113455
更新日期:2020-11-11 00:00:00
abstract::Dietary protein sources have profound effects on children and young animals, and are important for the gut barrier function and immune resilience. Milk and soy are the main sources of protein for children and young animals after weaning. The objective of this study was to compare the effects of dairy and soy proteins ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12092739
更新日期:2020-09-08 00:00:00
abstract::Probiotics are linked to positive regulatory effects on the immune system. The aim of the study was to examine the association between the exposure of probiotics via dietary supplements or via infant formula by the age of 1 year and the development of celiac disease autoimmunity (CDA) and celiac disease among a cohort...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11081790
更新日期:2019-08-02 00:00:00
abstract::Since 1998, the U.S. has mandated folic acid (FA) fortification of certain grain products to reduce the risk of neural tube defects. Folate intake and red blood cell (RBC) folate concentrations increased substantially post-intervention, although recent studies raise concerns about the level of ongoing benefit. This st...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9090994
更新日期:2017-09-08 00:00:00
abstract::The purpose of this study was to examine the impact of a sport nutrition education and life-skills intervention on sport nutrition knowledge (SNK), attitudes/beliefs and dietary behaviors relevant to sport nutrition among high school (HS) soccer players. Three assessments were done over the 2-year intervention (baseli...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10111636
更新日期:2018-11-02 00:00:00
abstract::Polyphenols (PPs) are the naturally occurring bioactive components in fruits and vegetables, and they are the most abundant antioxidant in the human diet. Studies are suggesting that ingestion of PPs might be helpful to ameliorate metabolic syndromes that may contribute in the prevention of several chronic disorders l...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu13010206
更新日期:2021-01-12 00:00:00
abstract::The lack of effective treatment for chronic discomfort without negative side effects highlights the need for alternative treatments. Pain Bloc-R is a natural health product composed of vitamins B6, B12, D, white willow bark extract, Angelica root extract, acetyl L-carnitine HCl, caffeine, L-theanine, Benfotiamine, and...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12061831
更新日期:2020-06-19 00:00:00
abstract::This investigation examined the impact of Montmorency tart cherry concentrate (MC) on physiological indices of oxidative stress, inflammation and muscle damage across 3 days simulated road cycle racing. Trained cyclists (n = 16) were divided into equal groups and consumed 30 mL of MC or placebo (PLA), twice per day fo...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu6020829
更新日期:2014-02-21 00:00:00
abstract::This study sought to elucidate the multi-level factors that influence behaviors underlying high childhood stunting and widespread micronutrient deficiencies in Kiribati. This two-phase formative research study had an emergent and iterative design using the socio-ecological model as the guiding theoretical framework. P...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11061330
更新日期:2019-06-13 00:00:00
abstract::Disordered eating in adolescents who participate in sports is an issue of great concern. However, very few studies have examined the prevalence of sport-related determinants of disturbed eating attitudes and behaviours (DEABs) in sport-involved adolescents. The present study aims to assess body image and DEABs in the ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11123061
更新日期:2019-12-14 00:00:00
abstract::Vitamin K is a composite term referring to a group of fat-soluble vitamins that function as a cofactor for the enzyme γ-glutamyl carboxylase (GGCX), which activates a number of vitamin K-dependent proteins (VKDPs) involved in haemostasis and vascular and bone health. Accumulating evidence demonstrates that chronic kid...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu11010168
更新日期:2019-01-14 00:00:00
abstract::Congenital sucrase-isomaltase deficiency (CSID) is an autosomal recessive disorder of carbohydrate maldigestion and malabsorption caused by mutations in the sucrase-isomaltase (SI) gene. SI, together with maltase-glucoamylase (MGAM), belongs to the enzyme family of disaccharidases required for breakdown of -glycosidi...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11102290
更新日期:2019-09-25 00:00:00
abstract::One-anastomosis gastric bypass is a promising type of bariatric surgery, but it may lead to a deficiency in important nutrients, such as fatty acids. The short-term effects of one-anastomosis gastric bypass on serum fatty acids have not been studied thus far. Therefore, the aim of this study was to determine the effec...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12010187
更新日期:2020-01-09 00:00:00
abstract::The Australian front-of-pack labelling system, Health Star Rating (HSR), does not include whole grain (WG) in its algorithm, but uses dietary fibre (DF), despite Dietary Guidelines recommending WG over refined grain (RG) foods. This study aimed to determine how effectively HSR differentiates WG and RG foods. Product l...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11020415
更新日期:2019-02-15 00:00:00
abstract::The sex differences in malnutrition and hypertension during adolescence is largely inconclusive. There is also a paucity of data on the sex-specific correlates of malnutrition and hypertension for adolescents. Hence, this study aimed to assess the association between malnutrition, pre-hypertension/hypertension (PHH) a...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12092737
更新日期:2020-09-08 00:00:00
abstract::The present study compares the bioavailability of vitamin B12 (B12) of dairy products or synthetic B12, using the pig as an experimental model for humans. Eleven pigs were used in a cross-over design to assess the net portal drained viscera (PDV) flux of blood plasma B12 after ingestion of tofu (TF; devoid of B12), Sw...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10091134
更新日期:2018-08-21 00:00:00
abstract::Maternal nutrition and lifestyle in pregnancy are important modifiable factors for both maternal and offspring's health. Although the Mediterranean diet has beneficial effects on health, recent studies have shown low adherence in Europe. This study aimed to assess the Mediterranean diet adherence in 266 pregnant women...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12082179
更新日期:2020-07-22 00:00:00
abstract::Lutein is the predominant carotenoid in the developing primate brain and retina, and may have important functional roles. However, its bioaccumulation pattern during early development is not understood. In this pilot study, we investigated whether carotenoid supplementation of infant formula enhanced lutein tissue dep...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9010051
更新日期:2017-01-10 00:00:00