Abstract：
:Probiotics are linked to positive regulatory effects on the immune system. The aim of the study was to examine the association between the exposure of probiotics via dietary supplements or via infant formula by the age of 1 year and the development of celiac disease autoimmunity (CDA) and celiac disease among a cohort of 6520 genetically susceptible children. Use of probiotics during the first year of life was reported by 1460 children. Time-to-event analysis was used to examine the associations. Overall exposure of probiotics during the first year of life was not associated with either CDA (n = 1212) (HR 1.15; 95%CI 0.99, 1.35; p = 0.07) or celiac disease (n = 455) (HR 1.11; 95%CI 0.86, 1.43; p = 0.43) when adjusting for known risk factors. Intake of probiotic dietary supplements, however, was associated with a slightly increased risk of CDA (HR 1.18; 95%CI 1.00, 1.40; p = 0.043) compared to children who did not get probiotics. It was concluded that the overall exposure of probiotics during the first year of life was not associated with CDA or celiac disease in children at genetic risk.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Uusitalo U,Andren Aronsson C,Liu X,Kurppa K,Yang J,Liu E,Skidmore J,Winkler C,Rewers MJ,Hagopian WA,She JX,Toppari J,Ziegler AG,Akolkar B,Norris JM,Virtanen SM,Krischer JP,Agardh D,TEDDY Study Group.doi
10.3390/nu11081790subject
Has Abstractpub_date
2019-08-02 00:00:00issue
8issn
2072-6643pii
nu11081790journal_volume
11pub_type
杂志文章相关文献
Nutrients文献大全abstract：:The present study evaluated the reliability of equations using spot urine (SU) samples in the estimation of 24-hour urine sodium excretion (24-HUNa). Equations estimating 24-HUNa from SU samples were derived from first-morning SU of 101 participants (52.4 ± 11.1 years, range 24-70 years). Equations developed by us and...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu6062360
更新日期：2014-06-20 00:00:00
abstract：:The circadian rhythm of urinary sodium excretion is related to the diurnal blood pressure regulation (BP) and the nocturnal dipping pattern. The renal sodium excretion expressed as daytime/nighttime ratio impacts BP, but a limited number of studies have investigated this topic to date. In this cross-sectional study, w...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12072013
更新日期：2020-07-07 00:00:00
abstract：BACKGROUND:Several natural products have been reported to elicit beneficial effects against neurodegenerative disorders due to their vitamin E contents. However, the neuroprotective efficacy of palm oil or its tocotrienol-rich fraction (TRF) from the pre-clinical cell and animal studies have not been systematically rev...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12020521
更新日期：2020-02-18 00:00:00
abstract：:[6S]-5-methyltetrahydrofolic acid (MTHF) is a proposed replacement for folic acid (FA) in diets and prenatal supplements. This study compared the effects of these two forms on maternal metabolism and hypothalamic gene expression. Pregnant Wistar rats received an AIN-93G diet with recommended FA (1X, 2 mg/kg, control),...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu13010048
更新日期：2020-12-25 00:00:00
abstract：:In addition to exhibiting antioxidant properties, conjugated linoleic acid (CLA) and vitamin E may modulate gene expression of endogenous antioxidant enzymes. Depending on cellular microenvironments, such modulation reflects either antioxidant or prooxidant outcomes. Although epidemiological/experimental studies have ...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu2070725
更新日期：2010-07-01 00:00:00
abstract：:High sugar intake in childhood has been linked to obesity. However, the role of macronutrient substitutions and associations with metabolic health remain unclear. We examined associations of carbohydrate intake and its subtypes with body composition and metabolic health among 3573 children participating in a populatio...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12071940
更新日期：2020-06-30 00:00:00
abstract：:Angiopoietin-like protein 4 (ANGPTL-4) regulates lipidic metabolism and affects energy homeostasis. However, its function in children with obesity remains unknown. We investigated plasma ANGPTL-4 levels in children and its relationship with body mass index (BMI) and different lipidic parameters such as free fatty acid...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11061340
更新日期：2019-06-14 00:00:00
abstract：:Chronic hyperglycemia increases oxidative stress, activates inflammatory pathways and reduces nerve growth factor (NGF) among diabetic patients, which contribute to development of diabetic peripheral neuropathy (DPN). Tocotrienol-Rich Vitamin E (Tocovid) possesses potent antioxidant and anti-inflammatory properties wh...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12051522
更新日期：2020-05-23 00:00:00
abstract：:Blood concentration of vitamin A (VA), which is present as different molecules, i.e., mainly retinol and provitamin A carotenoids, plus retinyl esters in the postprandial period after a VA-containing meal, is affected by numerous factors: dietary VA intake, VA absorption efficiency, efficiency of provitamin A caroteno...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu9030246
更新日期：2017-03-08 00:00:00
abstract：BACKGROUND:The aim of this study was to investigate total water intake (TWI) from water, beverages and foods among Italian adults and the elderly. METHODS:Data of 2607 adults and the elderly, aged 18-75 years from the last national food consumption survey, INRAN-SCAI 2005-06, were used to evaluate the TWI. The INRAN-S...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu8110674
更新日期：2016-10-26 00:00:00
abstract：:Socio-economic status (SES) has an impact on food consumption in developing countries. However, the impact of SES on dietary patterns in Filipino school-aged children is currently unknown. The aim of this study was to fill this knowledge gap, using data from the 2013 National Nutrition Survey. Dietary intake of 11,691...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11122910
更新日期：2019-12-02 00:00:00
abstract：:Selenium (Se) is an essential micronutrient known for its antioxidant properties and health benefits, attributed to its presence in selenoproteins as the amino acid, selenocysteine. Selenocysteine lyase (Scly) catalyzes hydrolysis of selenocysteine to selenide and alanine, facilitating re-utilization of Se for de novo...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu10020159
更新日期：2018-01-31 00:00:00
abstract：:High sugar-sweetened beverage (SSB) consumption has been linked with obesity. The present study examined the associations between adolescent SSB intake and body mass index (BMI), waist circumference (WC), and overweight status in early adulthood, and modelled the association of alternative beverage substitution with B...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11122928
更新日期：2019-12-03 00:00:00
abstract：:4-Hydroxy-3-methoxycinnamic acid (HMCA), a hydroxycinnamic acid derivative, is abundant in fruits and vegetables, including oranges, carrots, rice bran, and coffee beans. Several beneficial effects of HMCA have been reported, including improvement of metabolic abnormalities in animal models and human studies. However,...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11051036
更新日期：2019-05-09 00:00:00
abstract：:Dietary supplements (DSs) and nutritional supplements (NSs) can enhance performance, recovery or training adaptations, however, some substances, dosages, and usage protocols are unsafe. Knowledge of the type and extent of use within populations enables strategies to be formulated to promote safe and effective use (whe...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11071462
更新日期：2019-06-27 00:00:00
abstract：:A growing literature is dedicated to the understanding of carotenoid beneficial health effects. However, the absorption process of this broad family of molecules is still poorly understood. These highly lipophilic plant metabolites are usually weakly absorbed. It was long believed that β-carotene absorption (the princ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11040838
更新日期：2019-04-13 00:00:00
abstract：:As the population is aging rapidly, there is a strong increase in the number of individuals with chronic disease and physical limitations. The decrease in skeletal muscle mass and function (sarcopenia) and the increase in fat mass (obesity) are important contributors to the development of physical limitations, which a...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu10050605
更新日期：2018-05-12 00:00:00
abstract：:Selenoneine is a novel organic selenium compound markedly found in the blood, muscles, and other tissues of fish. This study aimed to determine whether selenoneine attenuates hepatocellular injury and hepatic steatosis in a mouse model of non-alcoholic fatty liver disease (NAFLD). Mice lacking farnesoid X receptor (FX...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12061898
更新日期：2020-06-26 00:00:00
abstract：:Iron is an essential micronutrient that is involved in many functions in humans, as it plays a critical role in the growth and development of the central nervous system, among others. Premature and low birth weight infants have higher iron requirements due to increased postnatal growth compared to that of term infants...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11051090
更新日期：2019-05-16 00:00:00
abstract：:Vitamin D deficiency has been associated with depressive symptoms and reduced physical functioning. The aim of the study was to characterize the relationship between polymorphisms of the vitamin D receptor (VDR) gene and the quality of life in patients with autoimmune hepatitis (AIH) and primary biliary cholangitis (P...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12082244
更新日期：2020-07-27 00:00:00
abstract：:This scoping review examines the interaction of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) and genetic variants of various types of cancers. A comprehensive search was performed to identify controlled and observational studies conducted through August 2017. Eighteen unique studies were included: breast...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu12061647
更新日期：2020-06-02 00:00:00
abstract：:The objective of this study was to examine the relationship between different sleep parameters and energy and macronutrient intake in school-aged children. A total of 203 children 6 to 9 years of age participated in this cross-sectional study. Anthropometric measurements were taken first. Diet was assessed with 3-day ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11112568
更新日期：2019-10-24 00:00:00
abstract：:Egg-yolk based supplements have demonstrated biological effects. We have developed a novel processed egg-yolk (PEY) complement, and we have tested whether it has inflammation modulatory properties. These were evaluated in a lipopolysaccharide (LPS)-challenge in 1-month male rats by in vivo circulating cytokine profile...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12092699
更新日期：2020-09-04 00:00:00
abstract：:Home Artificial Nutrition (HAN) is a safe and efficacious technique that insures children's reintegration into the family, society and school. Epidemiological data on paediatric HAN in Italy are not available. AIM:to detect the prevalence and incidence of Home Parenteral Nutrition (HPN) and Home Enteral Nutrition (HE...
journal_title：Nutrients
pub_type： 杂志文章,多中心研究
doi：10.3390/nu10091311
更新日期：2018-09-16 00:00:00
abstract：:This study examined the relationship between diet quality scores and cardiometabolic risk factors in regionally-dwelling older Australian adults with increased cardiovascular risk. This study was a cross-sectional analysis of demographic, anthropometric, and cardiometabolic risk factor data from 458 participants of th...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12030860
更新日期：2020-03-23 00:00:00
abstract：:Low diet quality is a driver of general and micronutrient malnutrition in urban and rural areas. The objective was to compare malnutrition and micronutrient deficiencies linked to dietary intake among urban and rural schoolchildren from food insecure settings in Kenya. The cross-sectional study was conducted among urb...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12010207
更新日期：2020-01-13 00:00:00
abstract：:Gut microbiota composition is influenced by environmental factors and has been shown to impact body metabolism. OBJECTIVE:To assess the gut microbiota profile before and after Roux-en-Y gastric bypass (RYGB) and the correlation with food intake and postoperative type 2 diabetes remission (T2Dr). DESIGN:Gut microbiot...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12020278
更新日期：2020-01-21 00:00:00
abstract：:Globally, the prevalence of obesity is increasing which subsequently increases the risk of the development of obesity-related chronic diseases. Low-grade chronic inflammation and dysregulated adipose tissue inflammatory mediator/adipokine secretion are well-established in obesity, and these factors increase the risk o...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu6114760
更新日期：2014-10-30 00:00:00
abstract：:This study aimed to investigate the potential of cabbage-apple juice, fermented by Lactobacillus plantarum EM isolated from kimchi, to protect against obesity and dyslipidemia that are induced by a high-fat diet in a rat model. Male rats were fed a modified AIN-93M high-fat diet (HFD), the same diet supplemented with ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12041135
更新日期：2020-04-18 00:00:00
abstract：:Human milk oligosaccharides (HMOs) are multifunctional carbohydrates naturally present in human milk that act as prebiotics, prevent pathogen binding and infections, modulate the immune system and may support brain development in infants. HMOs composition is very individualized and differences in HMOs concentrations m...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11061358
更新日期：2019-06-17 00:00:00
