Severe epidemic myalgia with an elevated level of serum interleukin-6 caused by human parechovirus type 3: a case report and brief review of the literature.

Abstract:

BACKGROUND:Human parechovirus type 3 (HPeV-3) is known to cause cold-like symptoms, diarrhea, or severe infections such as sepsis in infants and children. In adults, HPeV-3 infection is rarely diagnosed because the symptoms are generally mild and self-limiting; however, this infection has been linked to epidemic myalgia, regardless of the presence of underlying diseases, immunosuppression, or sex. CASE PRESENTATION:We describe an adult case of severe systemic myalgia and orchiodynia after infection with HPeV-3, which was transmitted from the child of the patient. Interleukin-6 (IL-6) level was found to be elevated in the patient's serum. CONCLUSION:Severe myalgia associated with HPeV-3 infection is potentially caused by an elevated serum level of IL-6.

journal_name

BMC Infect Dis

journal_title

BMC infectious diseases

authors

Nakamura K,Saito K,Hara Y,Aoyagi T,Kitakawa K,Abe Y,Takemura H,Ikeda F,Kaku M,Kanemitsu K

doi

10.1186/s12879-018-3284-5

subject

Has Abstract

pub_date

2018-08-07 00:00:00

pages

381

issue

1

issn

1471-2334

pii

10.1186/s12879-018-3284-5

journal_volume

18

pub_type

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