Vaccination with Toxoplasma gondii calcium-dependent protein kinase 6 and rhoptry protein 18 encapsulated in poly(lactide-co-glycolide) microspheres induces long-term protective immunity in mice.

abstract：BACKGROUND:Although real-life results of sofosbuvir/simeprevir have been extensively reported from the United States, data from other geographical areas are limited. In the French observational cohort, ANRS CO22 HEPATHER, 9432 patients were given the new oral antivirals from December 2013 to June 30, 2018. We report th...

journal_title：BMC infectious diseases

authors： Laurain A,Metivier S,Haour G,Larrey D,Dorival C,Hezode C,Zoulim F,Marcellin P,Bourliere M,Zarski JP,Thabut D,Alric L,Ganne-Carrie N,Cales P,Bronowicki JP,Riachi G,Geist C,Causse X,Abergel A,Chazouilleres O,Mathuri

更新日期：2019-04-02 00:00:00

abstract：BACKGROUND:Identifying immunogens that induce HIV-1-specific immune responses is a lengthy process that can benefit from computational methods, which predict T-cell epitopes for various HLA types. METHODS:We tested the performance of the NetMHCpan4.0 computational neural network in re-identifying 93 T-cell epitopes th...

journal_title：BMC infectious diseases

authors： Bugembe DL,Ekii AO,Ndembi N,Serwanga J,Kaleebu P,Pala P

更新日期：2020-02-22 00:00:00

abstract：BACKGROUND:HIV self-testing (HIVST) can be performed using directly assisted and unassisted approaches in facilities or communities to reach different populations. The aim of this study was to compare the practicability and effectiveness of the two delivery approaches for HIVST, unassisted HIVST (UH) and directly assis...

journal_title：BMC infectious diseases

authors： Tonen-Wolyec S,Kayembe Tshilumba C,Batina-Agasa S,Marini Djang'eing'a R,Hayette MP,Belec L

更新日期：2020-11-11 00:00:00

abstract：BACKGROUND:A cost effective and efficient diagnostic tool for COVID-19 as near to the point of care (PoC) as possible would be a game changer in the current pandemic. We tested reverse transcription loop mediated isothermal amplification (RT-LAMP), a method which can produce results in under 30 min, alongside standard ...

journal_title：BMC infectious diseases

authors： Österdahl MF,Lee KA,Lochlainn MN,Wilson S,Douthwaite S,Horsfall R,Sheedy A,Goldenberg SD,Stanley CJ,Spector TD,Steves CJ

更新日期：2020-10-20 00:00:00

abstract：BACKGROUND:This retrospective study evaluated the performance of a lipoarabinomannan (LAM)-based immunological method for diagnosing pleural tuberculosis (TB) from pleural effusion samples. Results were compared to those obtained using conventional culture and molecular testing methods. METHODS:Suspected pleural TB pa...

journal_title：BMC infectious diseases

authors： Liang Q,Pang Y,Yang Y,Li H,Guo C,Yang X,Chen X

更新日期：2019-06-21 00:00:00

abstract：BACKGROUND:Amoebic liver abscess is the most common extra intestinal manifestation of amoebiasis in tropical countries. It usually presents with right hypochondrial pain, fever and anorexia. Amoebic liver abscess has gained clinical significance due to the wide variety of clinical presentations which can cause diagnost...

journal_title：BMC infectious diseases

authors： Ratnasamy V,Thirunavukarasu K,Selvam K,Arumugam M

更新日期：2016-12-08 00:00:00

abstract：BACKGROUND:To explore the kinetic changes in virology, specific antibody response and imaging during the clinical course of COVID-19. METHODS:This observational study enrolled 20 patients with COVID-19, who were hospitalized between January 20-April 6, 2020, in the two COVID-19 designated hospitals of Zhoushan, Zhejia...

journal_title：BMC infectious diseases

authors： Wang QJ,Yao YZ,Song JS,Wang Q,Xu LY,Bao ZJ,Mao DW,Zhou JH,Zhang ZE,Wang Y,Li YW,Wang HP,Li L,Pan HY,Zhang GQ,Li SB

更新日期：2020-11-10 00:00:00

abstract：BACKGROUND:Bacterial infections in the genital tract frequently result in morbidity through a variety of inflammation based symptoms. One component of the bacteria that may trigger host inflammatory response is their DNA. CpG motifs in this DNA are known targets for Toll-like receptor 9 (TLR9), which is a pathogen-reco...

journal_title：BMC infectious diseases

authors： Singer M,de Waaij DJ,Morré SA,Ouburg S

更新日期：2015-07-16 00:00:00

abstract：BACKGROUND:The association of Chlamydia pneumoniae with atherosclerosis is controversial. We investigated the presence of C. pneumoniae and other Chlamydia spp. in atheromatous carotid artery tissue. METHODS:Forty elective carotid endarterectomy patients were recruited (27 males, mean age 65 and 13 females mean age 68...

journal_title：BMC infectious diseases

authors： Ong GM,Coyle PV,Barros D'Sa AA,McCluggage WG,Duprex WP,O'Neill HJ,Wyatt DE,Bamford KB,O'Loughlin B,McCaughey C

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:After the onset of HAART, some HIV-infected individuals under treatment present a exacerbated inflammation in response to a latent or a previously treated opportunistic pathogen termed immune reconstitution inflammatory syndrome (IRIS). Few reports of tegumentary leishmaniasis have been described in associat...

journal_title：BMC infectious diseases

authors： Gois L,Badaró R,Schooley R,Grassi MF

更新日期：2015-02-03 00:00:00

abstract：BACKGROUND:Even though remarkable progress for diagnostics of pulmonary TB has been made, it is still a challenge to establish a definitive diagnosis for extrapulmonary TB (EPTB) in clinical practice. Among all the presentations of EPTB, cold abscesses are unusual and deceptive, which are often reported in the chest wa...

journal_title：BMC infectious diseases

authors： Gao W,Zeng Y,Chen W

更新日期：2020-06-12 00:00:00

abstract：BACKGROUND:Self-reported antiretroviral therapy (ART) adherence measures that are associated with plasma viral load (VL) are valuable to clinicians and researchers, but are rarely examined among groups vulnerable to dropping out of care. One-seventh of all those living with HIV pass through incarceration annually and c...

journal_title：BMC infectious diseases

authors： Cunningham WE,Nance RM,Golin CE,Flynn P,Knight K,Beckwith CG,Kuo I,Spaulding A,Taxman FS,Altice F,Delaney JA,Crane HM,Springer SA

更新日期：2019-10-29 00:00:00

abstract：BACKGROUND:Despite the successes of routine national childhood vaccination programmes, measles remains a public health concern. The purpose of this paper is to investigate how patterns of parental attitudes are linked to the decision-making process for or against MMR vaccination. This exploratory study was designed to ...

journal_title：BMC infectious diseases

authors： Weiss C,Schröpfer D,Merten S

更新日期：2016-08-11 00:00:00

abstract：BACKGROUND:Male urethritis is primary sexually transmitted. Northern Territory (NT) has the highest rates of gonococcal infection in Australia and local guidelines recommend empiric treatment with azithromycin and ceftriaxone for all men presenting with urethritis. As gonococcal drug resistance is a growing concern, th...

journal_title：BMC infectious diseases

authors： Chen W,Connor S,Gunathilake M

更新日期：2019-11-21 00:00:00

abstract：BACKGROUND:This multicenter study describes the type-specific prevalence of HPV infection in the general population from central and southern Italy, comparing the data with previously published Italian studies. METHODS:Women aged from 25 to 65 who attended cervical cancer screening in five different Italian regions we...

journal_title：BMC infectious diseases

authors： Giorgi Rossi P,Bisanzi S,Paganini I,Di Iasi A,Angeloni C,Scalisi A,Macis R,Pini MT,Chini F,Carozzi FM,HPV Prevalence Italian Working Group.

更新日期：2010-07-20 00:00:00

abstract：BACKGROUND:The prevalence of diabetes mellitus continues to inexorably rise in the United States and throughout the world. Lower limb amputations are a devastating comorbid complication of diabetes mellitus. Osteomyelitis increases the risk of amputation fourfold and commonly presages death. Antimicrobial therapy for d...

journal_title：BMC infectious diseases

authors： Bessesen MT,Doros G,Henrie AM,Harrington KM,Hermos JA,Bonomo RA,Ferguson RE,Huang GD,Brown ST

更新日期：2020-01-08 00:00:00

abstract：BACKGROUND:The increasing occurrence of multidrug resistant (MDR) bacteria arises at a time when there is a lack of antibiotics active against these pathogens and few new antimicrobials are in the pipelines of the pharmaceutical industry. Treatment of ventilator-associated pneumonia (VAP) caused especially by MDR Gram-...

journal_title：BMC infectious diseases

authors： Garnacho-Montero J,Corcia-Palomo Y,Amaya-Villar R,Martin-Villen L

更新日期：2014-11-28 00:00:00

abstract：:While true antimicrobial resistance to Chlamydia trachomatis is a rare occurrence, repeat chlamydia infections continue to be reported following treatment with a single 1 g dose of azithromycin or week long doxycycline - with considerable more concern about azithromycin treatment failure. While most repeat positive ca...

journal_title：BMC infectious diseases

authors： Kong FY,Hocking JS

更新日期：2015-07-29 00:00:00

abstract：BACKGROUND:The diagnostic accuracy of fine-needle aspiration (FNA) cytology for the diagnosis of tuberculous lymphadenitis (TBLN) is confounded by mimicking cytomorphologic disorders. The objective of this study was to determine whether supplementing FNA cytology with bacteriological methods improves the overall accura...

journal_title：BMC infectious diseases

authors： Abdissa K,Tadesse M,Bezabih M,Bekele A,Apers L,Rigouts L,Abebe G

更新日期：2014-12-31 00:00:00

abstract：BACKGROUND:Several symptoms are classically thought to be suggestive of pertussis in children, but the diagnostic value of these symptoms in adolescent and adult patients is unclear. We evaluated the accuracy of the clinical findings for the early presumptive diagnosis of pertussis in adolescent and adult patients. Fur...

journal_title：BMC infectious diseases

authors： Miyashita N,Akaike H,Teranishi H,Kawai Y,Ouchi K,Kato T,Hayashi T,Okimoto N

更新日期：2013-03-11 00:00:00

abstract：BACKGROUND:The increasing antimalarial drug resistance is a significant hindrance to malaria control and elimination programs. For the last six decades, chloroquine (CQ) plus pyrimethamine remains the first-line treatment for P. vivax malaria. Regions where both P. falciparum and P. vivax co-exist, P. vivax is exposed ...

journal_title：BMC infectious diseases

authors： Kaur H,Sehgal R,Kumar A,Bharti PK,Bansal D,Mohapatra PK,Mahanta J,Sultan AA

更新日期：2020-09-15 00:00:00

abstract：:After publication of the original article [1], the authors would like to add a co-author, Dr. Stephen Pan, who contributed sufficiently to this manuscript. ...

journal_title：BMC infectious diseases

authors： Huang W,Wu D,Ong JJ,Smith MK,Pan S,Yang F,Fu H,Tang W,Tucker JD

更新日期：2020-02-27 00:00:00

abstract：BACKGROUND:Delayed diagnosis and treatment of tuberculosis (TB) results in severe disease and a higher mortality. It also leads to an increased period of infectivity in the community. The objective of this study was to determine the length of delays, and analyze the factors affecting the delay from onset of symptoms of...

journal_title：BMC infectious diseases

authors： Yimer S,Bjune G,Alene G

更新日期：2005-12-12 00:00:00

abstract：BACKGROUND:Acute hepatitis A is a fecal-oral transmitted disease related to inadequate sanitary conditions. In addition to its traditional classification, several outbreaks in the men who have sex with men (MSM) population have resulted in acute hepatitis A being recognized as a sexually transmitted disease. However, f...

journal_title：BMC infectious diseases

authors： Chen NY,Liu ZH,Shie SS,Chen TH,Wu TS

更新日期：2017-06-20 00:00:00

abstract：BACKGROUND:In 2017, an outbreak of onychomadesis occurred in kindergarten H, Hubei province, China. We investigated the field to learn about the magnitude and reason of the outbreak. METHODS:The case definition was that a child with onychomadesis or transverse ridging (Beau's line) in fingernails and toenails without ...

journal_title：BMC infectious diseases

authors： Li D,Wu Y,Xing X,Huang J,Mao A,Liu T,Rao P,Qin W,Zhang L,Feng L,Gao S,Guan X

更新日期：2019-11-26 00:00:00

abstract：BACKGROUND:For a long time, the role of CD8(+) T cells in blood-stage malaria was not considered important because erythrocytes do not express major histocompatibility complex (MHC) class I proteins. While recent evidences suggest that CD8(+) T cells may play an important role during the erythrocytic phase of infection...

journal_title：BMC infectious diseases

authors： Hojo-Souza NS,Pereira DB,Passos LS,Gazzinelli-Guimarães PH,Cardoso MS,Tada MS,Zanini GM,Bartholomeu DC,Fujiwara RT,Bueno LL

更新日期：2015-01-31 00:00:00

abstract：BACKGROUND:The burden of mother-to-child transmission rate of HIV is high and risk factors are common in Ethiopia. This systematic review and meta-analysis intended to provide the pooled estimation of mother-to-child transmission rate and its risk factors in Ethiopia. METHODS:We searched PubMed, Google Scholar, EMBASE...

journal_title：BMC infectious diseases

authors： Endalamaw A,Demsie A,Eshetie S,Habtewold TD

更新日期：2018-06-22 00:00:00

abstract：BACKGROUND:The new HIV treatment guidelines in China recommend antiretroviral therapy (ART) for all people living with HIV, but significant gaps in implementation still exist. Pre-exposure prophylaxis (PrEP) can effectively reduce the risk of HIV transmission among men who have sex with men (MSM). This study assessed t...

journal_title：BMC infectious diseases

authors： Li J,Peng L,Gilmour S,Gu J,Ruan Y,Zou H,Hao C,Hao Y,Lau JT

更新日期：2018-11-28 00:00:00

abstract：BACKGROUND:In order to compare the transmissibility of the 2009 pH1N1 pandemic during successive waves of infections in summer and fall/winter in the Northern Hemisphere, and to assess the temporal changes during the course of the outbreak in relation to the intervention measures implemented, we analyze the epidemiolog...

journal_title：BMC infectious diseases

authors： Hsieh YH,Cheng KF,Wu TN,Li TC,Chen CY,Chen JH,Lin MH,Center for Infectious Education and Research Team.

更新日期：2011-12-02 00:00:00

abstract：BACKGROUND:Kazakhstan remains a high-burden TB prevalence country with a concomitent high-burden of multi-drug resistant tuberculosis. For this reason, we performed an in depth genetic diversity and population structure characterization of Mycobacterium tuberculosis complex (MTC) genetic diversity in Kazakhstan with bo...

journal_title：BMC infectious diseases

authors： Klotoe BJ,Kacimi S,Costa-Conceicão E,Gomes HM,Barcellos RB,Panaiotov S,Haj Slimene D,Sikhayeva N,Sengstake S,Schuitema AR,Akhalaia M,Alenova A,Zholdybayeva E,Tarlykov P,Anthony R,Refrégier G,Sola C

更新日期：2019-06-24 00:00:00