Self-reported measures in health research for people with intellectual disabilities: an inclusive pilot study on suitability and reliability.

abstract：BACKGROUND:Due to limited duration of follow up in clinical trials of cancer treatments, estimates of lifetime survival benefits are typically derived using statistical extrapolation methods. To justify the method used, a range of approaches have been proposed including statistical goodness-of-fit tests and comparing e...

journal_title：BMC medical research methodology

authors： Bullement A,Willis A,Amin A,Schlichting M,Hatswell AJ,Bharmal M

更新日期：2020-05-06 00:00:00

abstract：BACKGROUND:Retaining participants in cohort studies with multiple follow-up waves is difficult. Commonly, researchers are faced with the problem of missing data, which may introduce biased results as well as a loss of statistical power and precision. The STROBE guidelines von Elm et al. (Lancet, 370:1453-1457, 2007); V...

journal_title：BMC medical research methodology

authors： Karahalios A,Baglietto L,Carlin JB,English DR,Simpson JA

更新日期：2012-07-11 00:00:00

abstract：BACKGROUND:Two most important considerations in evaluation of survival prediction models are 1) predictability - ability to predict survival risks accurately and 2) reproducibility - ability to generalize to predict samples generated from different studies. We present approaches for assessment of reproducibility of sur...

journal_title：BMC medical research methodology

authors： Chen HC,Chen JJ

更新日期：2013-02-20 00:00:00

abstract：BACKGROUND:Many biological variables sampled from human subjects show a diurnal pattern, which poses special demands on the techniques used to analyze such data. Furthermore, most biological variables belong to nonlinear dynamical systems, which may make linear statistical techniques less suitable to analyze their dyna...

journal_title：BMC medical research methodology

authors： Toonen RB,Wardenaar KJ,Bos EH,van Ockenburg SL,de Jonge P

更新日期：2018-03-21 00:00:00

abstract：BACKGROUND:Persistent Pseudomonas aeruginosa (PPA) infection promotes lung function deterioration in children with cystic fibrosis (CF). Although early CF diagnosis through newborn screening (NBS) has been shown to provide nutritional/growth benefit, it is unclear whether NBS lowers the risk of PPA infection and how th...

journal_title：BMC medical research methodology

authors： Wang W,Chen MH,Chiou SH,Lai HC,Wang X,Yan J,Zhang Z

更新日期：2016-09-17 00:00:00

abstract：BACKGROUND:Joint models of longitudinal and time-to-event data are increasingly used to perform individual dynamic prediction of a risk of event. However the difficulty to perform inference in nonlinear models and to calculate the distribution of individual parameters has long limited this approach to linear mixed-effe...

journal_title：BMC medical research methodology

authors： Desmée S,Mentré F,Veyrat-Follet C,Sébastien B,Guedj J

更新日期：2017-07-17 00:00:00

abstract：BACKGROUND:Diagnostic tests are performed in a subset of the population who are at higher risk, resulting in undiagnosed cases among those who do not receive the test. This poses a challenge for estimating the prevalence of the disease in the study population, and also for studying the risk factors for the disease. ME...

journal_title：BMC medical research methodology

authors： Zhang N,Cheng S,Ambroggio L,Florin TA,Macaluso M

更新日期：2017-12-12 00:00:00

abstract：BACKGROUND:Competing risks are a common occurrence in survival analysis. They arise when a patient is at risk of more than one mutually exclusive event, such as death from different causes, and the occurrence of one of these may prevent any other event from ever happening. METHODS:There are two main approaches to mode...

journal_title：BMC medical research methodology

authors： Hinchliffe SR,Lambert PC

更新日期：2013-02-06 00:00:00

abstract：BACKGROUND:Within cancer care, dynamic evaluations of the loss in expectation of life provides useful information to patients as well as physicians. The loss of lifetime function yields the conditional loss in expectation of life given survival up to a specific time point. Due to the inevitable censoring in time-to-eve...

journal_title：BMC medical research methodology

authors： Jakobsen LH,Andersson TM,Biccler JL,El-Galaly TC,Bøgsted M

更新日期：2019-01-28 00:00:00

abstract：BACKGROUND:Modern modelling techniques may potentially provide more accurate predictions of binary outcomes than classical techniques. We aimed to study the predictive performance of different modelling techniques in relation to the effective sample size ("data hungriness"). METHODS:We performed simulation studies bas...

journal_title：BMC medical research methodology

authors： van der Ploeg T,Austin PC,Steyerberg EW

更新日期：2014-12-22 00:00:00

abstract：BACKGROUND:Family members are increasingly involved in the care of cancer patients, however many are not prepared for this challenging role. Intervention-based studies are valuable to inform the most appropriate and effective support for caregivers. Barriers in the recruitment of patient/caregiver dyads exist but the r...

journal_title：BMC medical research methodology

authors： Heckel L,Gunn KM,Livingston PM

更新日期：2018-11-21 00:00:00

abstract：BACKGROUND:Typically, randomization software should allow users to exert control over the different aspects of randomization including block design, provision of unique identifiers and control over the format and type of program output. While some of these characteristics have been addressed by available software, none...

journal_title：BMC medical research methodology

authors： Saghaei M

更新日期：2004-11-09 00:00:00

abstract：BACKGROUND:International clinical trials are now rapidly expanding into Asia. However, the proportion of global trials is higher in South Korea compared to Japan despite implementation of similar governmental support in both countries. The difference in clinical trial environment might influence the respective physicia...

journal_title：BMC medical research methodology

authors： Ito-Ihara T,Hong JH,Kim OJ,Sumi E,Kim SY,Tanaka S,Narita K,Hatta T,Choi EK,Choi KJ,Miyagawa T,Minami M,Murayama T,Yokode M

更新日期：2013-10-25 00:00:00

abstract：BACKGROUND:In recent months, multiple efforts have sought to characterize COVID-19 social distancing policy responses. These efforts have used various coding frameworks, but many have relied on coding methodologies that may not adequately describe the gradient in social distancing policies as states "re-open." METHODS...

journal_title：BMC medical research methodology

authors： Lane J,Garrison MM,Kelley J,Sarma P,Katz A

更新日期：2020-12-08 00:00:00

abstract：BACKGROUND:One of the biggest challenges for population health studies is the recruitment of participants. Questions that investigators have asked are "who volunteers for studies?" and "does recruitment method influence characteristics of the samples?" The purpose of this paper was to compare sample characteristics of ...

journal_title：BMC medical research methodology

authors： Leung BM,McDonald SW,Kaplan BJ,Giesbrecht GF,Tough SC

更新日期：2013-12-06 00:00:00

abstract：BACKGROUND:While randomised controlled trials (RCTs) provide high-quality evidence to guide practice, much routine care is not based upon available RCTs. This disconnect between evidence and practice is not sufficiently well understood. This case study explores this relationship using a novel approach. Better understan...

journal_title：BMC medical research methodology

authors： Byrne BE,Rooshenas L,Lambert HS,Blazeby JM

更新日期：2020-05-12 00:00:00

abstract：BACKGROUND:There is a recognised need to build primary care medication adherence services which are tailored to patients' needs. Continuous quality improvement of such services requires a regular working method of measuring adherence in order to monitor effectiveness. Self report has been considered the method of choic...

journal_title：BMC medical research methodology

authors： Garfield S,Clifford S,Eliasson L,Barber N,Willson A

更新日期：2011-11-03 00:00:00

abstract：BACKGROUND:Multistate models have become increasingly useful to study the evolution of a patient's state over time in intensive care units ICU (e.g. admission, infections, alive discharge or death in ICU). In addition, in critically-ill patients, data come from different ICUs, and because observations are clustered int...

journal_title：BMC medical research methodology

authors： Liquet B,Timsit JF,Rondeau V

更新日期：2012-06-15 00:00:00

abstract：BACKGROUND:Patient-reported outcome (PRO) measures play a key role in the advancement of patient-centered care research. The accuracy of inferences, relevance of predictions, and the true nature of the associations made with PRO data depend on the validity of these measures. Errors inherent to self-report measures can ...

journal_title：BMC medical research methodology

authors： Dowling NM,Bolt DM,Deng S,Li C

更新日期：2016-05-26 00:00:00

abstract：BACKGROUND:The Behavioral Risk Factor Surveillance System (BRFSS) is a network of health-related telephone surveys--conducted by all 50 states, the District of Columbia, and participating US territories-that receive technical assistance from CDC. Data users often aggregate BRFSS state samples for national estimates wit...

journal_title：BMC medical research methodology

authors： Iachan R,Pierannunzi C,Healey K,Greenlund KJ,Town M

更新日期：2016-11-15 00:00:00

abstract：BACKGROUND:In randomised controlled trials, the assumption of independence of individual observations is fundamental to the design, analysis and interpretation of studies. However, in individually randomised trials in primary care, this assumption may be violated because patients are naturally clustered within primary ...

journal_title：BMC medical research methodology

authors： Stuart B,Becque T,Moore M,Little P

更新日期：2020-04-15 00:00:00

abstract：BACKGROUND:Multilevel models for non-normal outcomes are widely used in medical and health sciences research. While methods for interpreting fixed effects are well-developed, methods to quantify and interpret random cluster variation and compare it with other sources of variation are less established. Random cluster va...

journal_title：BMC medical research methodology

authors： Glorioso TJ,Grunwald GK,Ho PM,Maddox TM

更新日期：2018-07-06 00:00:00

abstract：BACKGROUND:The Patient Reported Outcomes Measurement Information System 43-item short form (PROMIS-43) and the five-level EQ-5D (EQ-5D-5L) are recently developed measures of health-related quality of life (HRQL) that have potentially broad application in evaluating treatments and capturing burden of respiratory-related...

journal_title：BMC medical research methodology

authors： Lin FJ,Pickard AS,Krishnan JA,Joo MJ,Au DH,Carson SS,Gillespie S,Henderson AG,Lindenauer PK,McBurnie MA,Mularski RA,Naureckas ET,Vollmer WM,Lee TA,CONCERT Consortium.

更新日期：2014-06-16 00:00:00

abstract：BACKGROUND:Primary care databases are a major source of data for epidemiological and health services research. However, most studies are based on coded information, ignoring information stored in free text. Using the early presentation of rheumatoid arthritis (RA) as an exemplar, our objective was to estimate the exten...

journal_title：BMC medical research methodology

authors： Ford E,Nicholson A,Koeling R,Tate A,Carroll J,Axelrod L,Smith HE,Rait G,Davies KA,Petersen I,Williams T,Cassell JA

更新日期：2013-08-21 00:00:00

abstract：BACKGROUND:Surveys are established methods for collecting population data that are unavailable from other sources; however, response rates to surveys are declining. A number of methods have been identified to increase survey returns yet response rates remain low. This paper evaluates the impact of five selected methods...

journal_title：BMC medical research methodology

authors： Harrison S,Henderson J,Alderdice F,Quigley MA

更新日期：2019-03-20 00:00:00

abstract：BACKGROUND:The development of risk prediction models is of increasing importance in medical research - their use in practice, however, is rare. Among other reasons this might be due to the fact that thorough validation is often lacking. This study focuses on two Bayesian approaches of how to validate a prediction rule ...

journal_title：BMC medical research methodology

authors： Held U,Bové DS,Steurer J,Held L

更新日期：2012-07-20 00:00:00

abstract：BACKGROUND:Crowding in the emergency department (ED) is associated with increased mortality, increased treatment cost, and reduced quality of care. Crowding arises when demand exceed resources in the ED and a first sign may be increasing waiting time. We aimed to quantify predictors for departure from the ED, and relat...

journal_title：BMC medical research methodology

authors： Eiset AH,Kirkegaard H,Erlandsen M

更新日期：2019-03-29 00:00:00

abstract：BACKGROUND:Self-administered questionnaires are becoming increasingly common in general practice. Much research has explored methods to increase response rates but comparatively few studies have explored the effect of questionnaire administration on reported answers. METHODS:The aim of this study was to determine the ...

journal_title：BMC medical research methodology

authors： Desborough JA,Butters P,Bhattacharya D,Holland RC,Wright DJ

更新日期：2008-06-27 00:00:00

abstract：BACKGROUND:Polypharmacy can be either beneficial or harmful to children. We conducted a scoping review to examine the concept of pediatric polypharmacy: its definition, prevalence, extent and gaps in research. In this manuscript, we report our transdisciplinary scoping review methodology. METHODS:After establishing a ...

journal_title：BMC medical research methodology

authors： Bakaki PM,Staley J,Liu R,Dawson N,Golchin N,Horace A,Johnson H,Waldron J,Winterstein A,Kleinman LC,Bolen SD

更新日期：2018-10-04 00:00:00

abstract：BACKGROUND:Studies examining incident heart failure (HF) have been limited to select populations. To examine incident HF with broader generalizability, there is need to assemble a HF-free cohort using a geographically-diverse sample. We aimed to develop and validate a simple medication-based strategy for assembling a H...

journal_title：BMC medical research methodology

authors： Goyal P,Mefford MT,Chen L,Sterling MR,Durant RW,Safford MM,Levitan EB

更新日期：2020-03-04 00:00:00