Suitability of measures of self-reported medication adherence for routine clinical use: a systematic review.

abstract：BACKGROUND:To provide empirical evidence about prevalence, reporting and handling of missing outcome data in systematic reviews with network meta-analysis and acknowledgement of their impact on the conclusions. METHODS:We conducted a systematic survey including all published systematic reviews of randomized controlled...

journal_title：BMC medical research methodology

authors： Spineli LM,Yepes-Nuñez JJ,Schünemann HJ

更新日期：2018-10-24 00:00:00

abstract：BACKGROUND:There is increasing awareness that meta-analyses require a sufficiently large information size to detect or reject an anticipated intervention effect. The required information size in a meta-analysis may be calculated from an anticipated a priori intervention effect or from an intervention effect suggested b...

journal_title：BMC medical research methodology

authors： Wetterslev J,Thorlund K,Brok J,Gluud C

更新日期：2009-12-30 00:00:00

abstract：BACKGROUND:In low-income settings, key outcomes such as biomarkers or clinical assessments are often missing for a substantial proportion of the study population. The aim of this study was to assess the extent to which Heckman-type selection models can create unbiased estimates in such settings. METHODS:We introduce t...

journal_title：BMC medical research methodology

authors： Koné S,Bonfoh B,Dao D,Koné I,Fink G

更新日期：2019-12-09 00:00:00

abstract：BACKGROUND:Chemotherapy is expected to reduce cancer deaths (CD), while possibly being harmful in terms of non-cancer deaths (NCD) because of toxicity. Peto's log-rank test is popular in the medical literature, but its operating characteristics are barely known. We compared this test to the most common ones in the stat...

journal_title：BMC medical research methodology

authors： Rotolo F,Michiels S

更新日期：2014-05-29 00:00:00

abstract：BACKGROUND:Cancer relapses may be useful to predict the risk of death. To take into account relapse information, the Landmark approach is popular. As an alternative, we propose the joint frailty model for a recurrent event and a terminal event to derive dynamic predictions of the risk of death. METHODS:The proposed pr...

journal_title：BMC medical research methodology

authors： Mauguen A,Rachet B,Mathoulin-Pélissier S,Lawrence GM,Siesling S,MacGrogan G,Laurent A,Rondeau V

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:In clinical trials, study designs may focus on assessment of superiority, equivalence, or non-inferiority, of a new medicine or treatment as compared to a control. Typically, evidence in each of these paradigms is quantified with a variant of the null hypothesis significance test. A null hypothesis is assume...

journal_title：BMC medical research methodology

authors： van Ravenzwaaij D,Monden R,Tendeiro JN,Ioannidis JPA

更新日期：2019-03-29 00:00:00

abstract：BACKGROUND:Quantitative Microbial Risk Assessment (QMRA), a modelling approach, is used to assess health risks. Inputs into the QMRA process include data that characterise the intensity, frequency and duration of exposure to risk(s). Data gaps for water exposure assessment include the duration and frequency of urban no...

journal_title：BMC medical research methodology

authors： O'Toole JE,Sinclair MI,Leder K

更新日期：2009-11-09 00:00:00

abstract：BACKGROUND:In many studies the information of patients who are dying in the hospital is censored when examining the change in length of hospital stay (cLOS) due to hospital-acquired infections (HIs). While appropriate estimators of cLOS are available in literature, the existence of the bias due to censoring of deaths w...

journal_title：BMC medical research methodology

authors： Rahman S,von Cube M,Schumacher M,Wolkewitz M

更新日期：2018-05-30 00:00:00

abstract：BACKGROUND:Claims databases are generally considered inadequate for obesity research due to suboptimal capture of body mass index (BMI) measurements. This might not be true for bariatric surgery because of reimbursement requirements and changes in coding systems. We assessed the availability and validity of claims-base...

journal_title：BMC medical research methodology

authors： Li X,Lewis KH,Callaway K,Wharam JF,Toh S

更新日期：2020-09-07 00:00:00

abstract：BACKGROUND:International clinical trials are now rapidly expanding into Asia. However, the proportion of global trials is higher in South Korea compared to Japan despite implementation of similar governmental support in both countries. The difference in clinical trial environment might influence the respective physicia...

journal_title：BMC medical research methodology

authors： Ito-Ihara T,Hong JH,Kim OJ,Sumi E,Kim SY,Tanaka S,Narita K,Hatta T,Choi EK,Choi KJ,Miyagawa T,Minami M,Murayama T,Yokode M

更新日期：2013-10-25 00:00:00

abstract：BACKGROUND:Diabetes-related lower limb amputations are associated with considerable morbidity and mortality and are usually preceded by foot ulceration. The available systematic reviews of aggregate data are compromised because the primary studies report both adjusted and unadjusted estimates. As adjusted meta-analyses...

journal_title：BMC medical research methodology

authors： Crawford F,Anandan C,Chappell FM,Murray GD,Price JF,Sheikh A,Simpson CR,Maxwell M,Stansby GP,Young MJ,Abbott CA,Boulton AJ,Boyko EJ,Kastenbauer T,Leese GP,Monami M,Monteiro-Soares M,Rith-Najarian SJ,Veves A,Coates N

更新日期：2013-02-15 00:00:00

abstract：BACKGROUND:Researchers and policy makers have determined that accounting for productivity costs, or "indirect costs," may be as important as including direct medical expenditures when evaluating the societal value of health interventions. These costs are also important when estimating the global burden of disease. The ...

journal_title：BMC medical research methodology

authors： Menzin J,Marton JP,Menzin JA,Willke RJ,Woodward RM,Federico V

更新日期：2012-06-25 00:00:00

abstract：BACKGROUND:It is notoriously difficult to recruit patients to randomised controlled trials in primary care. This is particularly true when the disease process under investigation occurs relatively infrequently and must be investigated during a brief time window. Bell's palsy, an acute unilateral paralysis of the facial...

journal_title：BMC medical research methodology

authors： McKinstry B,Hammersley V,Daly F,Sullivan F

更新日期：2007-03-28 00:00:00

abstract：BACKGROUND:Multistate models have become increasingly useful to study the evolution of a patient's state over time in intensive care units ICU (e.g. admission, infections, alive discharge or death in ICU). In addition, in critically-ill patients, data come from different ICUs, and because observations are clustered int...

journal_title：BMC medical research methodology

authors： Liquet B,Timsit JF,Rondeau V

更新日期：2012-06-15 00:00:00

abstract：BACKGROUND:Regular and timely monitoring of blood glucose (BG) levels in hospitalized patients with diabetes mellitus is crucial to optimizing inpatient glycaemic control. However, methods to quantify timeliness as a measurement of quality of care are lacking. We propose an analytical approach that utilizes BG measurem...

journal_title：BMC medical research methodology

authors： Chen Y,Kao SL,Tai ES,Wee HL,Khoo EY,Ning Y,Salloway MK,Deng X,Tan CS

更新日期：2016-04-08 00:00:00

abstract：BACKGROUND:In a random effects meta-analysis model, true treatment effects for each study are routinely assumed to follow a normal distribution. However, normality is a restrictive assumption and the misspecification of the random effects distribution may result in a misleading estimate of overall mean for the treatmen...

journal_title：BMC medical research methodology

authors： Yamaguchi Y,Maruo K,Partlett C,Riley RD

更新日期：2017-07-19 00:00:00

abstract：BACKGROUND:The lack of suitable and reliable scales to measure self-reported health and health behaviour among people with intellectual disabilities (ID) is an important methodological challenge in health research. This study, which was undertaken together with co-researchers with ID, explores possibilities for self-re...

journal_title：BMC medical research methodology

authors： Vlot-van Anrooij K,Tobi H,Hilgenkamp TIM,Leusink GL,Naaldenberg J

更新日期：2018-07-16 00:00:00

abstract：BACKGROUND:The ethical, methodological, and technical aspects of pediatric research, often results in complications and delays in implementation. Our objective was to identify factors associated with the implementation duration of hospital-based pediatric studies. METHODS:All hospital-based pediatric studies sponsored...

journal_title：BMC medical research methodology

authors： Meier-Girard D,Tibi A,Abdoul H,Prot-Labarthe S,Brion F,Bourdon O,Alberti C

更新日期：2016-03-29 00:00:00

abstract：BACKGROUND:The longitudinal birth cohort study is the preferred design for studies of childhood health, particularly atopic disease. Still, prospective data collection depends on recollection of the medical history since the previous visit representing a potential recall-bias. We aimed to ascertain the quality of infor...

journal_title：BMC medical research methodology

authors： Vissing NH,Jensen SM,Bisgaard H

更新日期：2012-10-22 00:00:00

abstract：BACKGROUND:The systematic collection of high-quality mortality data is a prerequisite in designing relevant drowning prevention programmes. This descriptive study aimed to assess the quality (i.e., level of specificity) of cause-of-death reporting using ICD-10 drowning codes across 69 countries. METHODS:World Health O...

journal_title：BMC medical research methodology

authors： Lu TH,Lunetta P,Walker S

更新日期：2010-04-08 00:00:00

abstract：BACKGROUND:Multiple imputation is frequently used to deal with missing data in healthcare research. Although it is known that the outcome should be included in the imputation model when imputing missing covariate values, it is not known whether it should be imputed. Similarly no clear recommendations exist on: the util...

journal_title：BMC medical research methodology

authors： Kontopantelis E,White IR,Sperrin M,Buchan I

更新日期：2017-01-09 00:00:00

abstract：BACKGROUND:Longitudinal studies using data collected as part of usual care risk providing biased results if visit times are related to the outcome of interest. Statistical methods for mitigating this bias are available but rarely used. This lack of use could be attributed to a lack of need or to a lack of awareness of ...

journal_title：BMC medical research methodology

authors： Farzanfar D,Abumuamar A,Kim J,Sirotich E,Wang Y,Pullenayegum E

更新日期：2017-09-06 00:00:00

abstract：BACKGROUND:Statistical time series derived from administrative data sets form key indicators in measuring progress in addressing disadvantage in Aboriginal and Torres Strait Islander populations in Australia. However, inconsistencies in the reporting of Indigenous status can cause difficulties in producing reliable ind...

journal_title：BMC medical research methodology

authors： Lawrence D,Christensen D,Mitrou F,Draper G,Davis G,McKeown S,McAullay D,Pearson G,Zubrick SR

更新日期：2012-07-02 00:00:00

abstract：BACKGROUND:In randomised controlled trials, the assumption of independence of individual observations is fundamental to the design, analysis and interpretation of studies. However, in individually randomised trials in primary care, this assumption may be violated because patients are naturally clustered within primary ...

journal_title：BMC medical research methodology

authors： Stuart B,Becque T,Moore M,Little P

更新日期：2020-04-15 00:00:00

abstract：BACKGROUND:Multiple Imputation as usually implemented assumes that data are Missing At Random (MAR), meaning that the underlying missing data mechanism, given the observed data, is independent of the unobserved data. To explore the sensitivity of the inferences to departures from the MAR assumption, we applied the meth...

journal_title：BMC medical research methodology

authors： Héraud-Bousquet V,Larsen C,Carpenter J,Desenclos JC,Le Strat Y

更新日期：2012-06-08 00:00:00

abstract：BACKGROUND:While randomised controlled trials (RCTs) provide high-quality evidence to guide practice, much routine care is not based upon available RCTs. This disconnect between evidence and practice is not sufficiently well understood. This case study explores this relationship using a novel approach. Better understan...

journal_title：BMC medical research methodology

authors： Byrne BE,Rooshenas L,Lambert HS,Blazeby JM

更新日期：2020-05-12 00:00:00

abstract：BACKGROUND:Models of hepatitis C virus (HCV) kinetics are increasingly used to estimate and to compare in vivo drug's antiviral effectiveness of new potent anti-HCV agents. Viral kinetic parameters can be estimated using non-linear mixed effect models (NLMEM). Here we aimed to evaluate the performance of this approach ...

journal_title：BMC medical research methodology

authors： Laouénan C,Guedj J,Mentré F

更新日期：2013-04-25 00:00:00

abstract：BACKGROUND:Generic quality of life (QoL) instruments provide important measures of self-reported wellbeing that can be compared across healthy and clinical populations. The aim of this analysis is to validate the ten-item QoL instrument "QOL10", as well as to confirm the validity of the embedded "QOL5" questionnaire an...

journal_title：BMC medical research methodology

authors： Muller AE,Skurtveit S,Clausen T

更新日期：2016-05-23 00:00:00

abstract：BACKGROUND:Estimating the incidence of medical conditions using claims data often requires constructing a prevalence period that predates an event of interest, for instance the diagnosis of cancer, to exclude those with pre-existing conditions from the incidence risk set. Those conditions missed during the prevalence p...

journal_title：BMC medical research methodology

authors： Griffiths RI,O'Malley CD,Herbert RJ,Danese MD

更新日期：2013-03-06 00:00:00

abstract：BACKGROUND:Cross-cultural research with patient-reported outcomes measures (PROMs) assumes that the PROM in the target language will measure the same construct in the same way as the PROM in the source language. Yet translation methods are rarely used to qualitatively maximise construct equivalence or to describe the i...

journal_title：BMC medical research methodology

authors： Hawkins M,Cheng C,Elsworth GR,Osborne RH

更新日期：2020-05-26 00:00:00