Estimating required information size by quantifying diversity in random-effects model meta-analyses.

abstract：BACKGROUND:Glaucoma is a leading cause of avoidable blindness worldwide. Open angle glaucoma is the most common type of glaucoma. No randomised controlled trials have been conducted evaluating the effectiveness of glaucoma screening for reducing sight loss. It is unclear what the most appropriate intervention to be eva...

journal_title：BMC medical research methodology

authors： Glaucoma screening Platform Study group.,Burr JM,Campbell MK,Campbell SE,Francis JJ,Greene A,Hernández R,Hopkins D,McCann SK,Vale LD

更新日期：2011-04-21 00:00:00

abstract：BACKGROUND:Epidemiologic studies often struggle to adequately represent populations and outcomes of interest. Differences in methodology, data analysis and research questions often mean that reviews and synthesis of the existing literature have significant limitations. The current paper details our experiences in combi...

journal_title：BMC medical research methodology

authors： Allen J,Inder KJ,Lewin TJ,Attia JR,Kay-Lambkin FJ,Baker AL,Hazell T,Kelly BJ

更新日期：2013-10-05 00:00:00

abstract：BACKGROUND:The aim was to describe a strategy for recruitment of healthy volunteers (HV) to a randomized trial that assessed the efficacy of different telephone techniques to assist HV in performing cardiac massage for vital emergency. Participation in the randomized trial was not financially compensated, however HV we...

journal_title：BMC medical research methodology

authors： Luzurier Q,Damm C,Lion F,Daniel C,Pellerin L,Tavolacci MP

更新日期：2015-01-05 00:00:00

abstract：BACKGROUND:The longitudinal birth cohort study is the preferred design for studies of childhood health, particularly atopic disease. Still, prospective data collection depends on recollection of the medical history since the previous visit representing a potential recall-bias. We aimed to ascertain the quality of infor...

journal_title：BMC medical research methodology

authors： Vissing NH,Jensen SM,Bisgaard H

更新日期：2012-10-22 00:00:00

abstract：BACKGROUND:The term 'inequities' refers to avoidable differences rooted in injustice. This review examined whether or not, and how, quantitative studies identifying inequalities in risk factors and health service utilization for asthma explicitly addressed underlying inequities. Asthma was chosen because recent decades...

journal_title：BMC medical research methodology

authors： Greenwood HL,Edwards N,Hoogbruin A,Kahwa EK,Odhiambo ON,Buong JA

更新日期：2011-07-12 00:00:00

abstract：BACKGROUND:In low-income settings, key outcomes such as biomarkers or clinical assessments are often missing for a substantial proportion of the study population. The aim of this study was to assess the extent to which Heckman-type selection models can create unbiased estimates in such settings. METHODS:We introduce t...

journal_title：BMC medical research methodology

authors： Koné S,Bonfoh B,Dao D,Koné I,Fink G

更新日期：2019-12-09 00:00:00

abstract：BACKGROUND:There are detailed reviews about different recruitment strategies, but not with regard to differences between recruitment of hospital-based versus office-based physicians. Within this study, the two different recruitment schemes are compared. Advantages and disadvantages of different ways of recruitment in r...

journal_title：BMC medical research methodology

authors： Zeissig SR,Weyer-Elberich V,Emrich K,Binder H,Fischbeck S,Imruck BH,Friedrich-Mai P,Beutel ME,Blettner M

更新日期：2017-11-22 00:00:00

abstract：BACKGROUND:In recent months, multiple efforts have sought to characterize COVID-19 social distancing policy responses. These efforts have used various coding frameworks, but many have relied on coding methodologies that may not adequately describe the gradient in social distancing policies as states "re-open." METHODS...

journal_title：BMC medical research methodology

authors： Lane J,Garrison MM,Kelley J,Sarma P,Katz A

更新日期：2020-12-08 00:00:00

abstract：BACKGROUND:The "real" effect size of a medical therapy is constant over time. In contrast, the effect size reported in randomised controlled trials (RCTs) may change over time because the sum of all kinds of bias influencing the reported effectiveness is not necessarily constant. As this would affect the validity of me...

journal_title：BMC medical research methodology

authors： Gehr BT,Weiss C,Porzsolt F

更新日期：2006-05-11 00:00:00

abstract：BACKGROUND:Cluster randomised trials with unequal sized clusters often have lower precision than with clusters of equal size. To allow for this, sample sizes are inflated by a modified version of the design effect for clustering. These inflation factors are valid under the assumption that randomisation is stratified by...

journal_title：BMC medical research methodology

authors： Martin JT,Hemming K,Girling A

更新日期：2019-06-14 00:00:00

abstract：BACKGROUND:The rationale for commissioning community pulmonary rehabilitation programmes is based on evidence from randomised clinical trials. However, there are a number of reasons why similar programmes might be less effective outside the environment of a clinical trial. These include a less highly selected patient g...

journal_title：BMC medical research methodology

authors： Goyder EC,Strong M,Green A,Holmes MW,Miles G,Reddington O,Lawson R,Lee A,Basran G

更新日期：2013-08-13 00:00:00

abstract：BACKGROUND:Evidence-based health care is informed by results of randomized clinical trials (RCTs) and their syntheses in meta-analyses. When the trial outcomes measured are not clearly described in trial publications, knowledge synthesis, translation, and decision-making may be impeded. While heterogeneity in outcomes ...

journal_title：BMC medical research methodology

authors： Monsour A,Mew EJ,Patel S,Chee-A-Tow A,Saeed L,Santos L,Courtney DB,Watson PN,Monga S,Szatmari P,Offringa M,Butcher NJ

更新日期：2020-05-25 00:00:00

abstract：BACKGROUND:Physical activity is an important determinant of health. Walking is the most common physical activity performed by adults and the presence of sidewalks along roads is a determinant of walking. Geographic information systems (GIS) can be used to measure sidewalks; however, GIS sidewalk data are difficult to a...

journal_title：BMC medical research methodology

authors： Janssen I,Rosu A

更新日期：2012-03-29 00:00:00

abstract：BACKGROUND:Observational outcome studies of patients with obstructive sleep apnea (OSA) require adjustment for co-morbidity to produce valid results. The aim of this study was to evaluate whether the combination of administrative data and self-reported data provided a more complete estimate of co-morbidity among patien...

journal_title：BMC medical research methodology

authors： Ronksley PE,Tsai WH,Quan H,Faris P,Hemmelgarn BR

更新日期：2009-07-15 00:00:00

abstract：BACKGROUND:Information and theory beyond copula concepts are essential to understand the dependence relationship between several marginal covariates distributions. In a therapeutic trial data scheme, most of the time, censoring occurs. That could lead to a biased interpretation of the dependence relationship between ma...

journal_title：BMC medical research methodology

authors： Fontaine C,Daurès JP,Landais P

更新日期：2017-02-15 00:00:00

abstract：BACKGROUND:For practical reasons it is not easy to obtain fasting samples in large population health surveys. Non-fasting triglyceride (Tg) values are difficult to interpret. The authors compared the accuracy of statistically corrected non-fasting Tg values with true fasting values and estimated the misclassification o...

journal_title：BMC medical research methodology

authors： Sundvall J,Leiviskä J,Laatikainen T,Peltonen M,Salomaa V,Vanhala M,Korpi-Hyövälti E,Lauronen J,Alfthan G

更新日期：2011-05-10 00:00:00

abstract：BACKGROUND:Collection of buccal cells from saliva for DNA extraction offers a less invasive and convenient alternative to venipuncture blood collection that may increase participation in genetic epidemiologic studies. However, dried blood spot collection, which is also a convenient method, offers a means of collecting ...

journal_title：BMC medical research methodology

authors： Bhatti P,Kampa D,Alexander BH,McClure C,Ringer D,Doody MM,Sigurdson AJ

更新日期：2009-11-13 00:00:00

abstract：BACKGROUND:Greater transparency and, in particular, sharing of patient-level data for further scientific research is an increasingly important topic for the pharmaceutical industry and other organisations who sponsor and conduct clinical trials as well as generally in the interests of patients participating in studies....

journal_title：BMC medical research methodology

authors： Tucker K,Branson J,Dilleen M,Hollis S,Loughlin P,Nixon MJ,Williams Z

更新日期：2016-07-08 00:00:00

abstract：BACKGROUND:Growth Mixture Modeling (GMM) is commonly used to group individuals on their development over time, but convergence issues and impossible values are common. This can result in unreliable model estimates. Constraining variance parameters across classes or over time can solve these issues, but can also serious...

journal_title：BMC medical research methodology

authors： Sijbrandij JJ,Hoekstra T,Almansa J,Peeters M,Bültmann U,Reijneveld SA

更新日期：2020-11-12 00:00:00

abstract：BACKGROUND:This research aims to explore an identified gap in implementation science methodology, that is, how to assess context in implementation research. Context is among the strongest influences on implementation success but is a construct that is poorly understood and reported within the literature. Consequently, ...

journal_title：BMC medical research methodology

authors： Rogers L,De Brún A,McAuliffe E

更新日期：2020-06-15 00:00:00

abstract：BACKGROUND:Missing data are common in medical research, which can lead to a loss in statistical power and potentially biased results if not handled appropriately. Multiple imputation (MI) is a statistical method, widely adopted in practice, for dealing with missing data. Many academic journals now emphasise the importa...

journal_title：BMC medical research methodology

authors： Hayati Rezvan P,Lee KJ,Simpson JA

更新日期：2015-04-07 00:00:00

abstract：BACKGROUND:Patient-reported outcomes (PRO) are important as endpoints in clinical trials and epidemiological studies. Guidelines for the development of PRO instruments and analysis of PRO data have emphasized the need to report methods used for sample size planning. The Raschpower procedure has been proposed for sample...

journal_title：BMC medical research methodology

authors： Blanchin M,Guilleux A,Perrot B,Bonnaud-Antignac A,Hardouin JB,Sébille V

更新日期：2015-03-15 00:00:00

abstract：BACKGROUND:Generic quality of life (QoL) instruments provide important measures of self-reported wellbeing that can be compared across healthy and clinical populations. The aim of this analysis is to validate the ten-item QoL instrument "QOL10", as well as to confirm the validity of the embedded "QOL5" questionnaire an...

journal_title：BMC medical research methodology

authors： Muller AE,Skurtveit S,Clausen T

更新日期：2016-05-23 00:00:00

abstract：BACKGROUND:Route environments can positively influence people's active commuting and thereby contribute to public health. The Active Commuting Route Environment Scale (ACRES) was developed to study active commuters' perceptions of their route environments. However, bicycle commuters represent a small portion of the pop...

journal_title：BMC medical research methodology

authors： Wahlgren L,Schantz P

更新日期：2011-01-17 00:00:00

abstract：BACKGROUND:Randomized controlled trials are the gold-standard for clinical trials. However, randomization is not always feasible. In this article we propose a prospective and adaptive matched case-control trial design assuming that a control group already exists. METHODS:We propose and discuss an interim analysis step...

journal_title：BMC medical research methodology

authors： Weber D,Uhlmann L,Schönenberger S,Kieser M

更新日期：2019-07-16 00:00:00

abstract：BACKGROUND:Systematic reviews (SRs) must be of high quality. The purpose of our research was to compare the methodological and reporting quality of original versus updated Cochrane SRs to determine whether updating had improved these two quality dimensions. METHODS:We identified updated Cochrane SRs published in issue...

journal_title：BMC medical research methodology

authors： Shea B,Boers M,Grimshaw JM,Hamel C,Bouter LM

更新日期：2006-06-13 00:00:00

abstract：BACKGROUND:Health researchers undertake studies which combine qualitative and quantitative methods. Little attention has been paid to the structural issues affecting this mixed methods approach. We explored the facilitators and barriers to undertaking mixed methods studies in health research. METHODS:Face-to-face semi...

journal_title：BMC medical research methodology

authors： O'Cathain A,Nicholl J,Murphy E

更新日期：2009-12-09 00:00:00

abstract：BACKGROUND:The health regulatory focus is an application of Higgins' regulatory focus theory to a health-specific context. It explains individual differences in health motivation, strategies, and behavior. Previous research found the Health Regulatory Focus Scale (HRFS) to be a reliable and valid measure for the constr...

journal_title：BMC medical research methodology

authors： Schmalbach B,Zenger M,Brähler E,Petrowski K

更新日期：2020-03-02 00:00:00

abstract：BACKGROUND:Persistent Pseudomonas aeruginosa (PPA) infection promotes lung function deterioration in children with cystic fibrosis (CF). Although early CF diagnosis through newborn screening (NBS) has been shown to provide nutritional/growth benefit, it is unclear whether NBS lowers the risk of PPA infection and how th...

journal_title：BMC medical research methodology

authors： Wang W,Chen MH,Chiou SH,Lai HC,Wang X,Yan J,Zhang Z

更新日期：2016-09-17 00:00:00

abstract：:Clinical Decision Support Systems (CDSS) provide aid in clinical decision making and therefore need to take into consideration human, data interactions, and cognitive functions of clinical decision makers. The objective of this paper is to introduce a high level reference model that is intended to be used as a foundat...

journal_title：BMC medical research methodology

authors： Zikos D,DeLellis N

更新日期：2018-11-16 00:00:00