Blood spots as an alternative to whole blood collection and the effect of a small monetary incentive to increase participation in genetic association studies.

abstract：BACKGROUND:Claims databases are generally considered inadequate for obesity research due to suboptimal capture of body mass index (BMI) measurements. This might not be true for bariatric surgery because of reimbursement requirements and changes in coding systems. We assessed the availability and validity of claims-base...

journal_title：BMC medical research methodology

authors： Li X,Lewis KH,Callaway K,Wharam JF,Toh S

更新日期：2020-09-07 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine the standard tasks performed by clinical research coordinators (CRCs) in oncology clinical trials. METHODS:Forty-one CRCs were anonymously surveyed, using a four-page self-administered questionnaire focused on demographics, qualifications, and professional experien...

journal_title：BMC medical research methodology

authors： Rico-Villademoros F,Hernando T,Sanz JL,López-Alonso A,Salamanca O,Camps C,Rosell R

更新日期：2004-03-25 00:00:00

abstract：BACKGROUND:Dynamic risk models, which incorporate disease-free survival and repeated measurements over time, might yield more accurate predictions of future health status compared to static models. The objective of this study was to develop and apply a dynamic prediction model to estimate the risk of developing type 2 ...

journal_title：BMC medical research methodology

authors： Parast L,Mathews M,Friedberg MW

更新日期：2019-08-14 00:00:00

abstract：BACKGROUND:Evidence-based health care is informed by results of randomized clinical trials (RCTs) and their syntheses in meta-analyses. When the trial outcomes measured are not clearly described in trial publications, knowledge synthesis, translation, and decision-making may be impeded. While heterogeneity in outcomes ...

journal_title：BMC medical research methodology

authors： Monsour A,Mew EJ,Patel S,Chee-A-Tow A,Saeed L,Santos L,Courtney DB,Watson PN,Monga S,Szatmari P,Offringa M,Butcher NJ

更新日期：2020-05-25 00:00:00

abstract：BACKGROUND:General Practitioners (GPs) respond poorly to postal surveys. Consequently there is potential for reduced data quality and bias in the findings. In general population surveys, response to postal questionnaires may be improved by reducing their length and offering incentives. The aim of this study was to inve...

journal_title：BMC medical research methodology

authors： Cottrell E,Roddy E,Rathod T,Thomas E,Porcheret M,Foster NE

更新日期：2015-01-06 00:00:00

abstract：BACKGROUND:Cluster randomised controlled trials (CRCTs) are frequently used in health service evaluation. Assuming an average cluster size, required sample sizes are readily computed for both binary and continuous outcomes, by estimating a design effect or inflation factor. However, where the number of clusters are fix...

journal_title：BMC medical research methodology

authors： Hemming K,Girling AJ,Sitch AJ,Marsh J,Lilford RJ

更新日期：2011-06-30 00:00:00

abstract：BACKGROUND:Diet plays an important role in chronic disease, and the use of dietary pattern analysis has grown rapidly as a way of deconstructing the complexity of nutritional intake and its relation to health. Pattern analysis methods, such as principal component analysis (PCA), have been used to investigate various di...

journal_title：BMC medical research methodology

authors： Zhang F,Tapera TM,Gou J

更新日期：2018-10-29 00:00:00

abstract：BACKGROUND:When multiple endpoints are of interest in evidence synthesis, a multivariate meta-analysis can jointly synthesise those endpoints and utilise their correlation. A multivariate random-effects meta-analysis must incorporate and estimate the between-study correlation (rhoB). METHODS:In this paper we assess ma...

journal_title：BMC medical research methodology

authors： Riley RD,Abrams KR,Sutton AJ,Lambert PC,Thompson JR

更新日期：2007-01-12 00:00:00

abstract：BACKGROUND:Participants in voluntary research present a different demographic profile than those who choose not to participate, affecting the generalizability of many studies. Efforts to evaluate these differences have faced challenges, as little information is available from non-participants. Leveraging data from a re...

journal_title：BMC medical research methodology

authors： Dahrouge S,Armstrong CD,Hogg W,Singh J,Liddy C

更新日期：2019-08-07 00:00:00

abstract：BACKGROUND:The Computer Adaptive Test version of the Community Reintegration of Injured Service Members measure (CRIS-CAT) consists of three scales measuring Extent of, Perceived Limitations in, and Satisfaction with community integration. The CRIS-CAT was developed using item response theory methods. The purposes of t...

journal_title：BMC medical research methodology

authors： Resnik L,Borgia M,Ni P,Pirraglia PA,Jette A

更新日期：2012-09-17 00:00:00

abstract：BACKGROUND:Researchers and policy makers have determined that accounting for productivity costs, or "indirect costs," may be as important as including direct medical expenditures when evaluating the societal value of health interventions. These costs are also important when estimating the global burden of disease. The ...

journal_title：BMC medical research methodology

authors： Menzin J,Marton JP,Menzin JA,Willke RJ,Woodward RM,Federico V

更新日期：2012-06-25 00:00:00

abstract：BACKGROUND:The Patient Reported Outcomes Measurement Information System 43-item short form (PROMIS-43) and the five-level EQ-5D (EQ-5D-5L) are recently developed measures of health-related quality of life (HRQL) that have potentially broad application in evaluating treatments and capturing burden of respiratory-related...

journal_title：BMC medical research methodology

authors： Lin FJ,Pickard AS,Krishnan JA,Joo MJ,Au DH,Carson SS,Gillespie S,Henderson AG,Lindenauer PK,McBurnie MA,Mularski RA,Naureckas ET,Vollmer WM,Lee TA,CONCERT Consortium.

更新日期：2014-06-16 00:00:00

abstract：BACKGROUND:While randomised controlled trials (RCTs) provide high-quality evidence to guide practice, much routine care is not based upon available RCTs. This disconnect between evidence and practice is not sufficiently well understood. This case study explores this relationship using a novel approach. Better understan...

journal_title：BMC medical research methodology

authors： Byrne BE,Rooshenas L,Lambert HS,Blazeby JM

更新日期：2020-05-12 00:00:00

abstract：BACKGROUND:Evidence syntheses, and in particular systematic reviews (SRs), have become one of the cornerstones of evidence-based health care. The Assessment of Multiple Systematic Reviews (AMSTAR) tool has become the most widely used tool for investigating the methodological quality of SRs and is currently undergoing r...

journal_title：BMC medical research methodology

authors： Wegewitz U,Weikert B,Fishta A,Jacobs A,Pieper D

更新日期：2016-08-26 00:00:00

abstract：BACKGROUND:Data on lifetime exposures are often self-reported in epidemiologic studies, sometimes many years after the relevant age. Validity of self-reported data is usually inferred from their agreement with measured values, but few studies directly quantify the likely effects of reporting errors in body size and rep...

journal_title：BMC medical research methodology

authors： Cairns BJ,Liu B,Clennell S,Cooper R,Reeves GK,Beral V,Kuh D

更新日期：2011-01-17 00:00:00

abstract：BACKGROUND:Chronic Obstructive Pulmonary Disease (COPD) is currently the fifth leading cause of death in Australia, and there are marked differences in mortality trends between men and women. In this study, we have sought to model and forecast age related changes in COPD mortality over time for men and women separately...

journal_title：BMC medical research methodology

authors： Erbas B,Ullah S,Hyndman RJ,Scollo M,Abramson M

更新日期：2012-02-21 00:00:00

abstract：BACKGROUND:We demonstrate an application of Group-Based Trajectory Modeling (GBTM) based on the beta distribution. It is offered as an alternative to the normal distribution for modeling continuous longitudinal data that are poorly fit by the normal distribution even with censoring. The primary advantage of the beta di...

journal_title：BMC medical research methodology

authors： Elmer J,Jones BL,Nagin DS

更新日期：2018-11-26 00:00:00

abstract：BACKGROUND:The use of health-related quality of life (HRQoL) as an endpoint in cancer clinical trials is growing rapidly. Hence, research into the statistical approaches used to analyze HRQoL data is of major importance, and could lead to a better understanding of the impact of treatments on the everyday life and care ...

journal_title：BMC medical research methodology

authors： Barbieri A,Peyhardi J,Conroy T,Gourgou S,Lavergne C,Mollevi C

更新日期：2017-09-26 00:00:00

abstract：BACKGROUND:The reporting of randomised controlled trial (RCT) abstracts is of vital importance. The primary objective of this study was to investigate the association between structure format and RCT abstracts' quality of methodology reporting, informed by the current requirement and usage of structure formats by leadi...

journal_title：BMC medical research methodology

authors： Hua F,Walsh T,Glenny AM,Worthington H

更新日期：2018-01-10 00:00:00

abstract：BACKGROUND:Social-environmental data obtained from the US Census is an important resource for understanding health disparities, but rarely is the full dataset utilized for analysis. A barrier to incorporating the full data is a lack of solid recommendations for variable selection, with researchers often hand-selecting ...

journal_title：BMC medical research methodology

authors： Handorf E,Yin Y,Slifker M,Lynch S

更新日期：2020-12-10 00:00:00

abstract：BACKGROUND:Sero- prevalence studies often have a problem of missing data. Few studies report the proportion of missing data and even fewer describe the methods used to adjust the results for missing data. The objective of this review was to determine the analytical methods used for analysis in HIV surveys with missing ...

journal_title：BMC medical research methodology

authors： Mosha NR,Aluko OS,Todd J,Machekano R,Young T

更新日期：2020-03-14 00:00:00

abstract：BACKGROUND:Motivational Interviewing (MI), Brief Advice (BA) and Health Education (HE) are established smoking cessation induction methods for smokers with low desire to quit. Although randomized controlled trials (RCT's) have been frequently used to assess these interventions the temporal efficacy and effectiveness of...

journal_title：BMC medical research methodology

authors： Bani-Yaghoub M,Elhomani A,Catley D

更新日期：2018-06-13 00:00:00

abstract：BACKGROUND:It is widely recognised that the pursuit of sustainable development cannot be accomplished without addressing inequality, or observed differences between subgroups of a population. Monitoring health inequalities allows for the identification of health topics where major group differences exist, dimensions of...

journal_title：BMC medical research methodology

authors： Hosseinpoor AR,Nambiar D,Schlotheuber A,Reidpath D,Ross Z

更新日期：2016-10-19 00:00:00

abstract：BACKGROUND:Both scientists and the public routinely refer to randomized controlled trials (RCTs) as being the 'gold standard' of scientific evidence. Although there is no question that placebo-controlled RCTs play a significant role in the evaluation of new pharmaceutical treatments, especially when it is important to ...

journal_title：BMC medical research methodology

authors： Kaplan BJ,Giesbrecht G,Shannon S,McLeod K

更新日期：2011-05-11 00:00:00

abstract：BACKGROUND:When conducting a meta-analysis of a continuous outcome, estimated means and standard deviations from the selected studies are required in order to obtain an overall estimate of the mean effect and its confidence interval. If these quantities are not directly reported in the publications, they must be estima...

journal_title：BMC medical research methodology

authors： Kwon D,Reis IM

更新日期：2015-08-12 00:00:00

abstract：BACKGROUND:Quantitative survey of research articles, as an application of bibliometrics, is an effective tool for grasping overall trends in various medical research fields. This type of survey has been also applied to infectious disease research; however, previous studies were insufficient as they underestimated artic...

journal_title：BMC medical research methodology

authors： Takahashi-Omoe H,Omoe K,Okabe N

更新日期：2009-10-06 00:00:00

abstract：BACKGROUND:Although in health services survey research we strive for a high response rate, this must be balanced against the need to recruit participants ethically and considerately, particularly in surveys with a sensitive nature. In survey research there are no established recommendations to guide recruitment approac...

journal_title：BMC medical research methodology

authors： Hunt KJ,Shlomo N,Addington-Hall J

更新日期：2013-01-11 00:00:00

abstract：BACKGROUND:Two most important considerations in evaluation of survival prediction models are 1) predictability - ability to predict survival risks accurately and 2) reproducibility - ability to generalize to predict samples generated from different studies. We present approaches for assessment of reproducibility of sur...

journal_title：BMC medical research methodology

authors： Chen HC,Chen JJ

更新日期：2013-02-20 00:00:00

abstract：BACKGROUND:Missing data are common in medical research, which can lead to a loss in statistical power and potentially biased results if not handled appropriately. Multiple imputation (MI) is a statistical method, widely adopted in practice, for dealing with missing data. Many academic journals now emphasise the importa...

journal_title：BMC medical research methodology

authors： Hayati Rezvan P,Lee KJ,Simpson JA

更新日期：2015-04-07 00:00:00

abstract：BACKGROUND:Precise predictions of incidence and mortality rates due to breast cancer (BC) are required for planning of public health programs as well as for clinical services. A number of approaches has been established for prediction of mortality using stochastic models. The performance of these models intensely depen...

journal_title：BMC medical research methodology

authors： Mubarik S,Hu Y,Yu C

更新日期：2020-12-09 00:00:00