Measuring health-related quality of life in chronic obstructive pulmonary disease: properties of the EQ-5D-5L and PROMIS-43 short form.

abstract：BACKGROUND:The rationale for commissioning community pulmonary rehabilitation programmes is based on evidence from randomised clinical trials. However, there are a number of reasons why similar programmes might be less effective outside the environment of a clinical trial. These include a less highly selected patient g...

journal_title：BMC medical research methodology

authors： Goyder EC,Strong M,Green A,Holmes MW,Miles G,Reddington O,Lawson R,Lee A,Basran G

更新日期：2013-08-13 00:00:00

abstract：BACKGROUND:Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease, is a rare disease with extreme between-subject variability, especially with respect to rate of disease progression. This makes modelling a subject's disease progression, which is measured by the ALS Functional Rating Scale (ALSFRS), ver...

journal_title：BMC medical research methodology

authors： Karanevich AG,Statland JM,Gajewski BJ,He J

更新日期：2018-02-06 00:00:00

abstract：BACKGROUND:Patient-reported outcomes (PRO) are important as endpoints in clinical trials and epidemiological studies. Guidelines for the development of PRO instruments and analysis of PRO data have emphasized the need to report methods used for sample size planning. The Raschpower procedure has been proposed for sample...

journal_title：BMC medical research methodology

authors： Blanchin M,Guilleux A,Perrot B,Bonnaud-Antignac A,Hardouin JB,Sébille V

更新日期：2015-03-15 00:00:00

abstract：BACKGROUND:The primary aim of this study was to provide an estimate of effect size for the functional outcome of operative versus non-operative treatment for patients with an acute rupture of the Achilles tendon using accelerated rehabilitation for both groups of patients. The secondary aim was to assess the use of a c...

journal_title：BMC medical research methodology

authors： Kearney RS,Achten J,Parsons NR,Costa ML

更新日期：2011-04-05 00:00:00

abstract：BACKGROUND:To assess cross-cultural validity between Dutch and English versions of the FVQ_CYP, a patient-reported outcome measure developed in the United Kingdom (UK) for children and adolescents with (severe) visual impairment or blindness (VI for brevity) to measure functional vision. METHODS:The 36-item FVQ_CYP wa...

journal_title：BMC medical research methodology

authors： Elsman EBM,Tadić V,Peeters CFW,van Rens GHMB,Rahi JS,van Nispen RMA

更新日期：2019-12-03 00:00:00

abstract：BACKGROUND:Chemotherapy is expected to reduce cancer deaths (CD), while possibly being harmful in terms of non-cancer deaths (NCD) because of toxicity. Peto's log-rank test is popular in the medical literature, but its operating characteristics are barely known. We compared this test to the most common ones in the stat...

journal_title：BMC medical research methodology

authors： Rotolo F,Michiels S

更新日期：2014-05-29 00:00:00

abstract：BACKGROUND:In the present article, we propose an alternative method for dealing with negative affectivity (NA) biases in research, while investigating the association between a deleterious psychosocial environment at work and poor mental health. First, we investigated how strong NA must be to cause an observed correlat...

journal_title：BMC medical research methodology

authors： Arial M,Wild P

更新日期：2011-08-24 00:00:00

abstract：BACKGROUND:The Public Population Project in Genomics (P3G) is an organisation that aims to promote collaboration between researchers in the field of population-based genomics. The main objectives of P3G are to encourage collaboration between researchers and biobankers, optimize study design, promote the harmonization o...

journal_title：BMC medical research methodology

authors： Bennett DA,Little J,Masson LF,Minelli C

更新日期：2011-10-05 00:00:00

abstract：BACKGROUND:Diagnostic tests are performed in a subset of the population who are at higher risk, resulting in undiagnosed cases among those who do not receive the test. This poses a challenge for estimating the prevalence of the disease in the study population, and also for studying the risk factors for the disease. ME...

journal_title：BMC medical research methodology

authors： Zhang N,Cheng S,Ambroggio L,Florin TA,Macaluso M

更新日期：2017-12-12 00:00:00

abstract：BACKGROUND:It is widely recognised that the pursuit of sustainable development cannot be accomplished without addressing inequality, or observed differences between subgroups of a population. Monitoring health inequalities allows for the identification of health topics where major group differences exist, dimensions of...

journal_title：BMC medical research methodology

authors： Hosseinpoor AR,Nambiar D,Schlotheuber A,Reidpath D,Ross Z

更新日期：2016-10-19 00:00:00

abstract：BACKGROUND:In clinical trials, study designs may focus on assessment of superiority, equivalence, or non-inferiority, of a new medicine or treatment as compared to a control. Typically, evidence in each of these paradigms is quantified with a variant of the null hypothesis significance test. A null hypothesis is assume...

journal_title：BMC medical research methodology

authors： van Ravenzwaaij D,Monden R,Tendeiro JN,Ioannidis JPA

更新日期：2019-03-29 00:00:00

abstract：BACKGROUND:The Computer Adaptive Test version of the Community Reintegration of Injured Service Members measure (CRIS-CAT) consists of three scales measuring Extent of, Perceived Limitations in, and Satisfaction with community integration. The CRIS-CAT was developed using item response theory methods. The purposes of t...

journal_title：BMC medical research methodology

authors： Resnik L,Borgia M,Ni P,Pirraglia PA,Jette A

更新日期：2012-09-17 00:00:00

abstract：BACKGROUND:Primary care databases are a major source of data for epidemiological and health services research. However, most studies are based on coded information, ignoring information stored in free text. Using the early presentation of rheumatoid arthritis (RA) as an exemplar, our objective was to estimate the exten...

journal_title：BMC medical research methodology

authors： Ford E,Nicholson A,Koeling R,Tate A,Carroll J,Axelrod L,Smith HE,Rait G,Davies KA,Petersen I,Williams T,Cassell JA

更新日期：2013-08-21 00:00:00

abstract：BACKGROUND:Quantitative survey of research articles, as an application of bibliometrics, is an effective tool for grasping overall trends in various medical research fields. This type of survey has been also applied to infectious disease research; however, previous studies were insufficient as they underestimated artic...

journal_title：BMC medical research methodology

authors： Takahashi-Omoe H,Omoe K,Okabe N

更新日期：2009-10-06 00:00:00

abstract：BACKGROUND:Posttraumatic growth is the positive change resulting from traumatic experiences and is typically assessed with retrospective measures like the Posttraumatic Growth Inventory (PTGI). The PTGI was designed to include reference to a specific traumatic event, making it difficult to implement, without change, in...

journal_title：BMC medical research methodology

authors： Kaur N,Porter B,LeardMann CA,Tobin LE,Lemus H,Luxton DD,Millennium Cohort Study Team.

更新日期：2017-04-20 00:00:00

abstract：BACKGROUND:Competing risks are a common occurrence in survival analysis. They arise when a patient is at risk of more than one mutually exclusive event, such as death from different causes, and the occurrence of one of these may prevent any other event from ever happening. METHODS:There are two main approaches to mode...

journal_title：BMC medical research methodology

authors： Hinchliffe SR,Lambert PC

更新日期：2013-02-06 00:00:00

abstract：BACKGROUND:Longitudinal studies using data collected as part of usual care risk providing biased results if visit times are related to the outcome of interest. Statistical methods for mitigating this bias are available but rarely used. This lack of use could be attributed to a lack of need or to a lack of awareness of ...

journal_title：BMC medical research methodology

authors： Farzanfar D,Abumuamar A,Kim J,Sirotich E,Wang Y,Pullenayegum E

更新日期：2017-09-06 00:00:00

abstract：BACKGROUND:A strong need exists for a validated tool that clearly defines peer review report quality in biomedical research, as it will allow evaluating interventions aimed at improving the peer review process in well-performed trials. We aim to identify and describe existing tools for assessing the quality of peer rev...

journal_title：BMC medical research methodology

authors： Superchi C,González JA,Solà I,Cobo E,Hren D,Boutron I

更新日期：2019-03-06 00:00:00

abstract：BACKGROUND:Disease registers aim to collect information about all instances of a disease or condition in a defined population of individuals. Traditionally methods of operating disease registers have required that notifications of cases be identified by unique identifiers such as social security number or national iden...

journal_title：BMC medical research methodology

authors： Churches T

更新日期：2003-01-06 00:00:00

abstract：BACKGROUND:Many biological variables sampled from human subjects show a diurnal pattern, which poses special demands on the techniques used to analyze such data. Furthermore, most biological variables belong to nonlinear dynamical systems, which may make linear statistical techniques less suitable to analyze their dyna...

journal_title：BMC medical research methodology

authors： Toonen RB,Wardenaar KJ,Bos EH,van Ockenburg SL,de Jonge P

更新日期：2018-03-21 00:00:00

abstract：BACKGROUND:Controlled clinical trials of health care interventions are either explanatory or pragmatic. Explanatory trials test whether an intervention is efficacious; that is, whether it can have a beneficial effect in an ideal situation. Pragmatic trials measure effectiveness; they measure the degree of beneficial ef...

journal_title：BMC medical research methodology

authors： Godwin M,Ruhland L,Casson I,MacDonald S,Delva D,Birtwhistle R,Lam M,Seguin R

更新日期：2003-12-22 00:00:00

abstract：BACKGROUND:Many medicines are dosed to achieve a particular therapeutic range, and monitored using therapeutic drug monitoring (TDM). The evidence base for a therapeutic range can be evaluated using systematic reviews, to ensure it continues to reflect current indications, doses, routes and formulations, as well as upd...

journal_title：BMC medical research methodology

authors： Cooney L,Loke YK,Golder S,Kirkham J,Jorgensen A,Sinha I,Hawcutt D

更新日期：2017-06-02 00:00:00

abstract：BACKGROUND:Dichotomisation of continuous outcomes has been rightly criticised by statisticians because of the loss of information incurred. However to communicate a comparison of risks, dichotomised outcomes may be necessary. Peacock et al. developed a distributional approach to the dichotomisation of normally distribu...

journal_title：BMC medical research methodology

authors： Sauzet O,Ofuya M,Peacock JL

更新日期：2015-04-24 00:00:00

abstract：BACKGROUND:Physical activity is an important determinant of health. Walking is the most common physical activity performed by adults and the presence of sidewalks along roads is a determinant of walking. Geographic information systems (GIS) can be used to measure sidewalks; however, GIS sidewalk data are difficult to a...

journal_title：BMC medical research methodology

authors： Janssen I,Rosu A

更新日期：2012-03-29 00:00:00

abstract：BACKGROUND:The BSI-18 contains the three six-item scales somatization, depression, and anxiety as well as the Global Severity Index (GSI), including all 18 items. The BSI-18 is the latest and shortest of the multidimensional versions of the Symptom-Checklist 90-R, but its psychometric properties have not been sufficien...

journal_title：BMC medical research methodology

authors： Franke GH,Jaeger S,Glaesmer H,Barkmann C,Petrowski K,Braehler E

更新日期：2017-01-26 00:00:00

abstract：BACKGROUND:Information and theory beyond copula concepts are essential to understand the dependence relationship between several marginal covariates distributions. In a therapeutic trial data scheme, most of the time, censoring occurs. That could lead to a biased interpretation of the dependence relationship between ma...

journal_title：BMC medical research methodology

authors： Fontaine C,Daurès JP,Landais P

更新日期：2017-02-15 00:00:00

abstract：BACKGROUND:The use of health-related quality of life (HRQoL) as an endpoint in cancer clinical trials is growing rapidly. Hence, research into the statistical approaches used to analyze HRQoL data is of major importance, and could lead to a better understanding of the impact of treatments on the everyday life and care ...

journal_title：BMC medical research methodology

authors： Barbieri A,Peyhardi J,Conroy T,Gourgou S,Lavergne C,Mollevi C

更新日期：2017-09-26 00:00:00

abstract：BACKGROUND:Although a variety of instruments are available that capture stress experience, the assessment of chronic stress has been hindered by the lack of economical screening instruments. Recently, an English-language version of the Trier Inventory for Chronic Stress (TICS-EN) consisting of 57 items according to a s...

journal_title：BMC medical research methodology

authors： Petrowski K,Braehler E,Schmalbach B,Hinz A,Bastianon C,Ritz T

更新日期：2020-12-16 00:00:00

abstract：BACKGROUND:Recruiting deaf and hard-of-hearing participants, particularly sign language-users, for genetics health service research is challenging due to communication barriers, mistrust toward genetics, and researchers' unfamiliarity with deaf people. Feelings of social exclusion and lack of social cohesion between re...

journal_title：BMC medical research methodology

authors： Kobayashi Y,Boudreault P,Hill K,Sinsheimer JS,Palmer CG

更新日期：2013-11-25 00:00:00

abstract：BACKGROUND:Multistate models have become increasingly useful to study the evolution of a patient's state over time in intensive care units ICU (e.g. admission, infections, alive discharge or death in ICU). In addition, in critically-ill patients, data come from different ICUs, and because observations are clustered int...

journal_title：BMC medical research methodology

authors： Liquet B,Timsit JF,Rondeau V

更新日期：2012-06-15 00:00:00