Onset of persistent pseudomonas aeruginosa infection in children with cystic fibrosis with interval censored data.

abstract：BACKGROUND:The lack of suitable and reliable scales to measure self-reported health and health behaviour among people with intellectual disabilities (ID) is an important methodological challenge in health research. This study, which was undertaken together with co-researchers with ID, explores possibilities for self-re...

journal_title：BMC medical research methodology

authors： Vlot-van Anrooij K,Tobi H,Hilgenkamp TIM,Leusink GL,Naaldenberg J

更新日期：2018-07-16 00:00:00

abstract：BACKGROUND:It is widely recognised that the pursuit of sustainable development cannot be accomplished without addressing inequality, or observed differences between subgroups of a population. Monitoring health inequalities allows for the identification of health topics where major group differences exist, dimensions of...

journal_title：BMC medical research methodology

authors： Hosseinpoor AR,Nambiar D,Schlotheuber A,Reidpath D,Ross Z

更新日期：2016-10-19 00:00:00

abstract：BACKGROUND:Syntheses of qualitative studies can inform health policy, services and our understanding of patient experience. Meta-ethnography is a systematic seven-phase interpretive qualitative synthesis approach well-suited to producing new theories and conceptual models. However, there are concerns about the quality ...

journal_title：BMC medical research methodology

authors： France EF,Ring N,Thomas R,Noyes J,Maxwell M,Jepson R

更新日期：2014-11-19 00:00:00

abstract：BACKGROUND:The Public Population Project in Genomics (P3G) is an organisation that aims to promote collaboration between researchers in the field of population-based genomics. The main objectives of P3G are to encourage collaboration between researchers and biobankers, optimize study design, promote the harmonization o...

journal_title：BMC medical research methodology

authors： Bennett DA,Little J,Masson LF,Minelli C

更新日期：2011-10-05 00:00:00

abstract：BACKGROUND:Both scientists and the public routinely refer to randomized controlled trials (RCTs) as being the 'gold standard' of scientific evidence. Although there is no question that placebo-controlled RCTs play a significant role in the evaluation of new pharmaceutical treatments, especially when it is important to ...

journal_title：BMC medical research methodology

authors： Kaplan BJ,Giesbrecht G,Shannon S,McLeod K

更新日期：2011-05-11 00:00:00

abstract：BACKGROUND:Multilevel models for non-normal outcomes are widely used in medical and health sciences research. While methods for interpreting fixed effects are well-developed, methods to quantify and interpret random cluster variation and compare it with other sources of variation are less established. Random cluster va...

journal_title：BMC medical research methodology

authors： Glorioso TJ,Grunwald GK,Ho PM,Maddox TM

更新日期：2018-07-06 00:00:00

abstract：BACKGROUND:Chronic Obstructive Pulmonary Disease (COPD) is currently the fifth leading cause of death in Australia, and there are marked differences in mortality trends between men and women. In this study, we have sought to model and forecast age related changes in COPD mortality over time for men and women separately...

journal_title：BMC medical research methodology

authors： Erbas B,Ullah S,Hyndman RJ,Scollo M,Abramson M

更新日期：2012-02-21 00:00:00

abstract：BACKGROUND:Few studies have compared methods to correct for retest effects or practice effects in settings where an acute event could influence test performance, such as major surgery. Our goal in this study was to evaluate the use of different methods to correct for the effects of practice or retest on repeated test a...

journal_title：BMC medical research methodology

authors： Racine AM,Gou Y,Fong TG,Marcantonio ER,Schmitt EM,Travison TG,Inouye SK,Jones RN

更新日期：2018-07-03 00:00:00

abstract：BACKGROUND:Although some nonparametric methods have been proposed in the literature to test for the equality of median survival times for censored data in medical research, in general they have inflated type I error rates, which make their use limited in practice, especially when the sample sizes are small. METHODS:In...

journal_title：BMC medical research methodology

authors： Chen Z,Zhang G

更新日期：2016-03-16 00:00:00

abstract：BACKGROUND:In a random effects meta-analysis model, true treatment effects for each study are routinely assumed to follow a normal distribution. However, normality is a restrictive assumption and the misspecification of the random effects distribution may result in a misleading estimate of overall mean for the treatmen...

journal_title：BMC medical research methodology

authors： Yamaguchi Y,Maruo K,Partlett C,Riley RD

更新日期：2017-07-19 00:00:00

abstract：BACKGROUND:Physical activity is an important determinant of health. Walking is the most common physical activity performed by adults and the presence of sidewalks along roads is a determinant of walking. Geographic information systems (GIS) can be used to measure sidewalks; however, GIS sidewalk data are difficult to a...

journal_title：BMC medical research methodology

authors： Janssen I,Rosu A

更新日期：2012-03-29 00:00:00

abstract：BACKGROUND:It has been demonstrated that the enclosure of money with a mailed questionnaire increases the response rate significantly. We evaluated scratch lottery tickets as an alternative to cash. METHODS:1500 randomly selected Norwegians between the ages of 40 and 65 years were sent a short questionnaire. 250 recei...

journal_title：BMC medical research methodology

authors： Finsen V,Storeheier AH

更新日期：2006-04-28 00:00:00

abstract：BACKGROUND:There is increasing awareness that meta-analyses require a sufficiently large information size to detect or reject an anticipated intervention effect. The required information size in a meta-analysis may be calculated from an anticipated a priori intervention effect or from an intervention effect suggested b...

journal_title：BMC medical research methodology

authors： Wetterslev J,Thorlund K,Brok J,Gluud C

更新日期：2009-12-30 00:00:00

abstract：BACKGROUND:Epidemiologic studies often struggle to adequately represent populations and outcomes of interest. Differences in methodology, data analysis and research questions often mean that reviews and synthesis of the existing literature have significant limitations. The current paper details our experiences in combi...

journal_title：BMC medical research methodology

authors： Allen J,Inder KJ,Lewin TJ,Attia JR,Kay-Lambkin FJ,Baker AL,Hazell T,Kelly BJ

更新日期：2013-10-05 00:00:00

abstract：BACKGROUND:Interventions in occupational health often target worksites rather than individuals. The objective of this paper is to describe the (lack of) stability in units of analysis in occupational health and safety intervention projects directed toward worksites. METHODS:A case study approach is used to describe na...

journal_title：BMC medical research methodology

authors： Olsen O,Albertsen K,Nielsen ML,Poulsen KB,Gron SM,Brunnberg HL

更新日期：2008-06-13 00:00:00

abstract：BACKGROUND:Dichotomisation of continuous outcomes has been rightly criticised by statisticians because of the loss of information incurred. However to communicate a comparison of risks, dichotomised outcomes may be necessary. Peacock et al. developed a distributional approach to the dichotomisation of normally distribu...

journal_title：BMC medical research methodology

authors： Sauzet O,Ofuya M,Peacock JL

更新日期：2015-04-24 00:00:00

abstract：BACKGROUND:Clinical quality registries and other systems that conduct routine post-discharge surveillance of patient outcomes following surgery may have difficulty surveying patients who have limited proficiency in the language of the healthcare provider. Interpreter proxies (family and carers) are often used due to li...

journal_title：BMC medical research methodology

authors： Xue D,Churches T,Armstrong E,Mittal R,Naylor JM,Harris IA

更新日期：2019-11-14 00:00:00

abstract：BACKGROUND:A recent paper found that terminal digits of statistical values in Nature deviated significantly from an equiprobable distribution, indicating errors or inconsistencies in rounding. This finding, as well as the discovery that a large percentage of p values were inconsistent with reported test statistics, led...

journal_title：BMC medical research methodology

authors： Jeng M

更新日期：2006-09-13 00:00:00

abstract：BACKGROUND:The initial vanguard cohort of the U.S. National Children's Study was a pregnancy and birth cohort study that sought to enroll some women prior to pregnancy, and to assess exposures early in pregnancy. METHODS:During the recruitment phase (2009-2010), geographically based sampling was used to recruit women ...

journal_title：BMC medical research methodology

authors： Stanford JB,Brenner R,Fetterer D,Palmer L,Schoendorf KC,U.S. National Children’s Study.

更新日期：2015-09-24 00:00:00

abstract：BACKGROUND:We would expect information on adverse drug reactions in randomised clinical trials to be easily retrievable from specific searches of electronic databases. However, complete retrieval of such information may not be straightforward, for two reasons. First, not all clinical drug trials provide data on the fre...

journal_title：BMC medical research methodology

authors： Derry S,Loke YK,Aronson JK

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Outcomes in observational studies may not best estimate those expected in the HIV vaccine efficacy trials. We compared retention in Simulated HIV Vaccine Efficacy Trials (SiVETs) and observational cohorts drawn from two key populations in Uganda. METHODS:Two SiVETs were nested within two observational cohor...

journal_title：BMC medical research methodology

authors： Abaasa A,Todd J,Nash S,Mayanja Y,Kaleebu P,Fast PE,Price M

更新日期：2020-02-12 00:00:00

abstract：BACKGROUND:Health researchers undertake studies which combine qualitative and quantitative methods. Little attention has been paid to the structural issues affecting this mixed methods approach. We explored the facilitators and barriers to undertaking mixed methods studies in health research. METHODS:Face-to-face semi...

journal_title：BMC medical research methodology

authors： O'Cathain A,Nicholl J,Murphy E

更新日期：2009-12-09 00:00:00

abstract：BACKGROUND:Evidence syntheses, and in particular systematic reviews (SRs), have become one of the cornerstones of evidence-based health care. The Assessment of Multiple Systematic Reviews (AMSTAR) tool has become the most widely used tool for investigating the methodological quality of SRs and is currently undergoing r...

journal_title：BMC medical research methodology

authors： Wegewitz U,Weikert B,Fishta A,Jacobs A,Pieper D

更新日期：2016-08-26 00:00:00

abstract：BACKGROUND:The Computer Adaptive Test version of the Community Reintegration of Injured Service Members measure (CRIS-CAT) consists of three scales measuring Extent of, Perceived Limitations in, and Satisfaction with community integration. The CRIS-CAT was developed using item response theory methods. The purposes of t...

journal_title：BMC medical research methodology

authors： Resnik L,Borgia M,Ni P,Pirraglia PA,Jette A

更新日期：2012-09-17 00:00:00

abstract：BACKGROUND:A key component of the implementation process is identifying potential barriers and facilitators that need to be addressed. The Theoretical Domains Framework (TDF) is one of the most commonly used frameworks for this purpose. When applying the TDF, it is critical to understand the context in which behaviours...

journal_title：BMC medical research methodology

authors： Etherington N,Rodrigues IB,Giangregorio L,Graham ID,Hoens AM,Kasperavicius D,Kelly C,Moore JE,Ponzano M,Presseau J,Sibley KM,Straus S

更新日期：2020-06-26 00:00:00

abstract：BACKGROUND:The COVID-19 pandemic has evolved into one of the most impactful health crises in modern history, compelling researchers to explore innovative ways to efficiently collect public health data in a timely manner. Social media platforms have been explored as a research recruitment tool in other settings; however...

journal_title：BMC medical research methodology

authors： Ali SH,Foreman J,Capasso A,Jones AM,Tozan Y,DiClemente RJ

更新日期：2020-05-13 00:00:00

abstract：BACKGROUND:Studies in both paediatric and psychiatric settings often experience problems in recruitment. This can compromise the ability of the study to recruit to target, meaning studies are potentially underpowered. It can also result in a biased sample if a non-representative group are selectively recruited. Recruit...

journal_title：BMC medical research methodology

authors： Loades ME,Smith L,Higson-Sweeney N,Beasant L,Stallard P,Kessler D,Crawley E

更新日期：2019-04-27 00:00:00

abstract：BACKGROUND:Many medicines are dosed to achieve a particular therapeutic range, and monitored using therapeutic drug monitoring (TDM). The evidence base for a therapeutic range can be evaluated using systematic reviews, to ensure it continues to reflect current indications, doses, routes and formulations, as well as upd...

journal_title：BMC medical research methodology

authors： Cooney L,Loke YK,Golder S,Kirkham J,Jorgensen A,Sinha I,Hawcutt D

更新日期：2017-06-02 00:00:00

abstract：BACKGROUND:Surveys are established methods for collecting population data that are unavailable from other sources; however, response rates to surveys are declining. A number of methods have been identified to increase survey returns yet response rates remain low. This paper evaluates the impact of five selected methods...

journal_title：BMC medical research methodology

authors： Harrison S,Henderson J,Alderdice F,Quigley MA

更新日期：2019-03-20 00:00:00

abstract：BACKGROUND:Estimating the incidence of medical conditions using claims data often requires constructing a prevalence period that predates an event of interest, for instance the diagnosis of cancer, to exclude those with pre-existing conditions from the incidence risk set. Those conditions missed during the prevalence p...

journal_title：BMC medical research methodology

authors： Griffiths RI,O'Malley CD,Herbert RJ,Danese MD

更新日期：2013-03-06 00:00:00