Abstract:
BACKGROUND:Although some nonparametric methods have been proposed in the literature to test for the equality of median survival times for censored data in medical research, in general they have inflated type I error rates, which make their use limited in practice, especially when the sample sizes are small. METHODS:In this paper, we propose a new nonparametric test with a simple test statistic to compare median survival times. RESULTS:The results from our comprehensive simulation study show the new test controls type I error rate very well under all situations considered, even for small sample sizes. In addition, it has comparable detecting power compared to existing methods. Another advantage of the proposed test is its relatively simple formula that requires less computation. CONCLUSIONS:We propose a new statistical method for comparing survival curves based on their medians. The new method can be easily implemented and applied to censored event time data.
journal_name
BMC Med Res Methodoljournal_title
BMC medical research methodologyauthors
Chen Z,Zhang Gdoi
10.1186/s12874-016-0133-3subject
Has Abstractpub_date
2016-03-16 00:00:00pages
33issn
1471-2288pii
10.1186/s12874-016-0133-3journal_volume
16pub_type
杂志文章abstract:BACKGROUND:Disease registers aim to collect information about all instances of a disease or condition in a defined population of individuals. Traditionally methods of operating disease registers have required that notifications of cases be identified by unique identifiers such as social security number or national iden...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-3-1
更新日期:2003-01-06 00:00:00
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journal_title:BMC medical research methodology
pub_type: 杂志文章
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journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-14-46
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journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-019-0726-8
更新日期:2019-04-24 00:00:00
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journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-017-0352-2
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journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-017-0308-6
更新日期:2017-02-14 00:00:00
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pub_type: 杂志文章
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journal_title:BMC medical research methodology
pub_type: 杂志文章
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更新日期:2011-05-11 00:00:00
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journal_title:BMC medical research methodology
pub_type: 杂志文章
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更新日期:2013-12-06 00:00:00
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pub_type: 杂志文章
doi:10.1186/1471-2288-8-39
更新日期:2008-06-13 00:00:00
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journal_title:BMC medical research methodology
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更新日期:2019-04-27 00:00:00
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journal_title:BMC medical research methodology
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doi:10.1186/1471-2288-9-66
更新日期:2009-09-29 00:00:00
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journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-017-0339-z
更新日期:2017-04-20 00:00:00
abstract:BACKGROUND:The development of risk prediction models is of increasing importance in medical research - their use in practice, however, is rare. Among other reasons this might be due to the fact that thorough validation is often lacking. This study focuses on two Bayesian approaches of how to validate a prediction rule ...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-12-99
更新日期:2012-07-20 00:00:00
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journal_title:BMC medical research methodology
pub_type: 杂志文章,评审
doi:10.1186/s12874-015-0022-1
更新日期:2015-04-07 00:00:00
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journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-4-6
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journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-13-95
更新日期:2013-07-24 00:00:00
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journal_title:BMC medical research methodology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12874-018-0642-3
更新日期:2018-12-22 00:00:00
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journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-018-0485-y
更新日期:2018-03-21 00:00:00
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journal_title:BMC medical research methodology
pub_type: 杂志文章,评审
doi:10.1186/1471-2288-14-101
更新日期:2014-08-30 00:00:00
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journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-10-81
更新日期:2010-09-17 00:00:00
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journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-017-0382-9
更新日期:2017-07-17 00:00:00
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journal_title:BMC medical research methodology
pub_type: 杂志文章
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更新日期:2019-05-22 00:00:00
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journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-01106-8
更新日期:2020-09-07 00:00:00
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